htw
@heniek-htw.bsky.social
Look deep, patiently into nature & then you will understand everything better.
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htw
@heniek-htw.bsky.social
· Nov 14
Broken circadian clock: The emerging neuro-immune link connecting depression to cancer
This review systemically describes the fundamental mechanisms of #circadian clocks and the interacting relationships among broken circadian clock, #cancer & #depression.
👇
www.sciencedirect.com/science/arti...
This review systemically describes the fundamental mechanisms of #circadian clocks and the interacting relationships among broken circadian clock, #cancer & #depression.
👇
www.sciencedirect.com/science/arti...
Human tissues emit ultra-weak biophotons across a 200-900 nm spectrum at approximately 10⁻¹⁶ W/m² intensity. Emissions originate from radiative decay of electronically excited species generated primarily via oxidative metabolic processes, ROS reactions during mitochondrial respiration
November 23, 2025 at 6:08 PM
Human tissues emit ultra-weak biophotons across a 200-900 nm spectrum at approximately 10⁻¹⁶ W/m² intensity. Emissions originate from radiative decay of electronically excited species generated primarily via oxidative metabolic processes, ROS reactions during mitochondrial respiration
Reposted by htw
Being born with two X chromosomes brings a host of health benefits, and recognising this could lead to personalised medical treatments for men and women.
Women have supercharged immune systems and we now know why
Being born with two X chromosomes brings a host of health benefits, and recognising this could lead to personalised medical treatments for men and women
www.newscientist.com
November 22, 2025 at 7:11 PM
Being born with two X chromosomes brings a host of health benefits, and recognising this could lead to personalised medical treatments for men and women.
#Depression severity in adolescents correlates with #circadian desynchronization. These findings reveal the potential value of PER and SCN-OFC connectivity as biomarkers for MDD in adolescents.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 6:54 PM
#Depression severity in adolescents correlates with #circadian desynchronization. These findings reveal the potential value of PER and SCN-OFC connectivity as biomarkers for MDD in adolescents.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Light-induced conformational switching and magnetic sensitivity of Drosophila cryptochrome
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 6:44 PM
Light-induced conformational switching and magnetic sensitivity of Drosophila cryptochrome
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Knowledgebase of Circadian-Related Risk Factors for Cancer Pathogenesis and Personalized Medicine
bioinf.org.cn:9876
bioinf.org.cn:9876
bioinf.org.cn
November 22, 2025 at 6:06 PM
Knowledgebase of Circadian-Related Risk Factors for Cancer Pathogenesis and Personalized Medicine
bioinf.org.cn:9876
bioinf.org.cn:9876
This meta-analysis revealed significant negative association between suboptimal #sleep & poorer #mentalhealth (r=−0.20, 95% CI [−0.23, −0.16]), with subjective sleep quality (β=0.11–0.19) and sleep schedule regularity (β=0.08) emerging as stronger predictors than objective sleep duration (β=0.05).
Unpacking Sleep and Mental Health Disparities Across Childhood and Adolescence: A Meta-Analytic and Systematic Review
Children and adolescents from racial and ethnic minority and socioeconomically disadvantaged backgrounds are at greater risk for health disparities. T…
www.sciencedirect.com
November 22, 2025 at 6:04 PM
This meta-analysis revealed significant negative association between suboptimal #sleep & poorer #mentalhealth (r=−0.20, 95% CI [−0.23, −0.16]), with subjective sleep quality (β=0.11–0.19) and sleep schedule regularity (β=0.08) emerging as stronger predictors than objective sleep duration (β=0.05).
• We did a systematic review of seasons/gravity/geomagnetism affecting brain function
• We found evidence across both animal and human literature supporting the premise
• Evidence is, however, primarily behavioral, with inadequate mechanistic insights
www.sciencedirect.com/science/arti...
• We found evidence across both animal and human literature supporting the premise
• Evidence is, however, primarily behavioral, with inadequate mechanistic insights
www.sciencedirect.com/science/arti...
November 22, 2025 at 2:54 PM
• We did a systematic review of seasons/gravity/geomagnetism affecting brain function
• We found evidence across both animal and human literature supporting the premise
• Evidence is, however, primarily behavioral, with inadequate mechanistic insights
www.sciencedirect.com/science/arti...
• We found evidence across both animal and human literature supporting the premise
• Evidence is, however, primarily behavioral, with inadequate mechanistic insights
www.sciencedirect.com/science/arti...
Incorporating the #circadian context has not only clarified the IL-10 role in IAV infection but also underscored the pivotal #influence of circadian regulation on #immune responses.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 1:59 PM
Incorporating the #circadian context has not only clarified the IL-10 role in IAV infection but also underscored the pivotal #influence of circadian regulation on #immune responses.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
This review aimed to elucidate the physiological mechanisms underlying exercise-induced #sleep improvements and assess its potential as a sustainable, low-risk alternative to pharmacotherapy in insomnia management.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 1:58 PM
This review aimed to elucidate the physiological mechanisms underlying exercise-induced #sleep improvements and assess its potential as a sustainable, low-risk alternative to pharmacotherapy in insomnia management.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
From symptoms to systems: A comprehensive review of the clinical utility of classic and novel approaches to major #depression subtyping
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 1:56 PM
From symptoms to systems: A comprehensive review of the clinical utility of classic and novel approaches to major #depression subtyping
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The role of circadian rhythms is emerging as a contributor to healthy aging, with studies ranging from behavioral to molecular rhythms. In this review, we provide a summary of what is known about behavioral and systemic physiology rhythms with aging in humans.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 1:54 PM
The role of circadian rhythms is emerging as a contributor to healthy aging, with studies ranging from behavioral to molecular rhythms. In this review, we provide a summary of what is known about behavioral and systemic physiology rhythms with aging in humans.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Ginsenoside Re binds Drp1 Leu94 across species to restore mitochondrial homeostasis via Atg1/ULK1-dependent fission-mitophagy coupling in age-related degeneration
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 1:47 PM
Ginsenoside Re binds Drp1 Leu94 across species to restore mitochondrial homeostasis via Atg1/ULK1-dependent fission-mitophagy coupling in age-related degeneration
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Both persistently long and short #sleep duration trajectories are associated with an elevated risk of #sarcopenia, compared to persistently high-normal sleep duration trajectories among middle-aged and older Chinese adults.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 1:45 PM
Both persistently long and short #sleep duration trajectories are associated with an elevated risk of #sarcopenia, compared to persistently high-normal sleep duration trajectories among middle-aged and older Chinese adults.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Physical Activity during #COVID-19 Pandemic: A 5-Year Retrospect
Physical Activity during COVID-19 Pandemic: A 5-Year Retrospect
The purpose of this article is to provide a follow-up review of the impact of the SARS-CoV-2 Disease or Coronavirus Disease 2019 (COVID-19) pandemic o…
www.sciencedirect.com
November 22, 2025 at 1:22 PM
Physical Activity during #COVID-19 Pandemic: A 5-Year Retrospect
Long-term CoQ10 supplementation ameliorates weight gain, white adipocyte hypertrophy and inflammation in WAT, and metabolic disorders caused by combined estrogen deficiency and HFD, likely through its WAT browning effect.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 11:06 AM
Long-term CoQ10 supplementation ameliorates weight gain, white adipocyte hypertrophy and inflammation in WAT, and metabolic disorders caused by combined estrogen deficiency and HFD, likely through its WAT browning effect.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
This review aims to comprehensively summarize the underlying molecular mechanisms by which the cGAS-STING pathway regulates cellular senescence and aging.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 22, 2025 at 11:02 AM
This review aims to comprehensively summarize the underlying molecular mechanisms by which the cGAS-STING pathway regulates cellular senescence and aging.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The evidence suggests that TRE may modestly reduce TG levels, particularly in overweight individuals, with a limited impact on LDL-C, HDL-C, and TC. ADF demonstrated inconsistent effects on lipid profile. RIF presented modest improvements of TG and HDL-C.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 21, 2025 at 4:46 PM
The evidence suggests that TRE may modestly reduce TG levels, particularly in overweight individuals, with a limited impact on LDL-C, HDL-C, and TC. ADF demonstrated inconsistent effects on lipid profile. RIF presented modest improvements of TG and HDL-C.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Our findings indicate that a daily eating frequency of fewer than 3 times per day and a NFD of more than 12 hours are associated with an increased prevalence of diabetic kidney disease. Modifying circadian eating patterns may hold potential for improving renal outcomes in individuals with diabetes.
The association between circadian eating behaviors and diabetic kidney disease in diabetes mellitus patients: a cross-sectional analysis
Recent studies have suggested that circadian eating behaviors play a significant role in metabolic diseases and their related complications. However, …
www.sciencedirect.com
November 20, 2025 at 6:58 PM
Our findings indicate that a daily eating frequency of fewer than 3 times per day and a NFD of more than 12 hours are associated with an increased prevalence of diabetic kidney disease. Modifying circadian eating patterns may hold potential for improving renal outcomes in individuals with diabetes.
Higher screen time demonstrated significant associations with multiple adverse health outcomes- Lower physical activity levels, elevated BMI, reduced MQI, and poorer sleep quality.
Screen Time Impact on Muscle Health and Sleep Quality in School-Age Children - A cross sectional study
Excessive screen time poses significant health concerns for school-aged children. However, the relationships between screen time, muscle quality, and …
www.sciencedirect.com
November 20, 2025 at 4:30 PM
Higher screen time demonstrated significant associations with multiple adverse health outcomes- Lower physical activity levels, elevated BMI, reduced MQI, and poorer sleep quality.
Our study shows a direct link between the circadian rhythm and the response to Repair of DNA double-strand breaks in transcribed genes, opening strategies for chrono-chemotherapies based on topoisomerase poisons that induce DSBs in active loci.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope
Repair of DNA double-strand breaks (DSBs) produced in transcriptionally active chromatin occurs through a poorly characterized pathway called transcri…
www.sciencedirect.com
November 20, 2025 at 4:22 PM
Our study shows a direct link between the circadian rhythm and the response to Repair of DNA double-strand breaks in transcribed genes, opening strategies for chrono-chemotherapies based on topoisomerase poisons that induce DSBs in active loci.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
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#Mitochondria: An Integrative Hub Coordinating #Circadian Rhythms, #Metabolism, the #Microbiome, and #Immunity
www.frontiersin.org/journals/cel...
www.frontiersin.org/journals/cel...
November 20, 2025 at 3:50 PM
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Reposted by htw
📝 Online now - the Spotlight "Unlocking the protein code: how our organs age across a lifetime" from Dongxue Wang and Jing Yang.
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...
November 18, 2025 at 9:35 PM
📝 Online now - the Spotlight "Unlocking the protein code: how our organs age across a lifetime" from Dongxue Wang and Jing Yang.
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...
#Proteostasis #Aging #BiologicalClocks #Proteomics
Read it here: authors.elsevier.com/a/1m7Ts3S6Gf...