Greg Madej
@greg-madej.bsky.social
University of Regensburg | #cryoEM | #membrane #proteins
Well, I finally swapped the predictable pavement for some unpredictable trail running, and let's say my legs have feelings now—mostly bewilderment and slight betrayal. I'm back home, covered in dirt, slightly bruised.
Most importantly, I didn't need to call for a helicopter. Success!
Most importantly, I didn't need to call for a helicopter. Success!
October 26, 2025 at 3:36 PM
Well, I finally swapped the predictable pavement for some unpredictable trail running, and let's say my legs have feelings now—mostly bewilderment and slight betrayal. I'm back home, covered in dirt, slightly bruised.
Most importantly, I didn't need to call for a helicopter. Success!
Most importantly, I didn't need to call for a helicopter. Success!
Reposted by Greg Madej
Nanocosmos: Faster Than Your Quickest Thought!
"Physik goes Downtown Night 2025" featured science presented by speakers from RUN that was truly mind-blowing. They delivered fantastic talks about the movement of atoms at speeds that completely redefine "quick"! www.uni-regensburg.de/physik/schul...
"Physik goes Downtown Night 2025" featured science presented by speakers from RUN that was truly mind-blowing. They delivered fantastic talks about the movement of atoms at speeds that completely redefine "quick"! www.uni-regensburg.de/physik/schul...
October 26, 2025 at 3:25 PM
Nanocosmos: Faster Than Your Quickest Thought!
"Physik goes Downtown Night 2025" featured science presented by speakers from RUN that was truly mind-blowing. They delivered fantastic talks about the movement of atoms at speeds that completely redefine "quick"! www.uni-regensburg.de/physik/schul...
"Physik goes Downtown Night 2025" featured science presented by speakers from RUN that was truly mind-blowing. They delivered fantastic talks about the movement of atoms at speeds that completely redefine "quick"! www.uni-regensburg.de/physik/schul...
The @ziegler-lab-ur.bsky.social delegation survived the Munich Half Marathon! This Trial of Spirit demanded the Force be strong with us. And the Force was extraordinarily strong with @katjaurbansky.bsky.social Her exceptional pace has earned her a promotion to the Council of cryoKnights - so cool!
October 14, 2025 at 4:19 AM
The @ziegler-lab-ur.bsky.social delegation survived the Munich Half Marathon! This Trial of Spirit demanded the Force be strong with us. And the Force was extraordinarily strong with @katjaurbansky.bsky.social Her exceptional pace has earned her a promotion to the Council of cryoKnights - so cool!
Reposted by Greg Madej
Enjoy the picture to see moments from the visit — from the Robin Hood statue to the lab and evening strolls through Nottingham! 🌿
@uniregensburg.bsky.social
4/4
@uniregensburg.bsky.social
4/4
October 7, 2025 at 6:31 PM
Enjoy the picture to see moments from the visit — from the Robin Hood statue to the lab and evening strolls through Nottingham! 🌿
@uniregensburg.bsky.social
4/4
@uniregensburg.bsky.social
4/4
Reposted by Greg Madej
The visit highlighted the spirit of our project: connecting scientists across borders and disciplines to advance cutting-edge research together to uncover the mechanisms plants use to perceive water stress.
3/4
3/4
October 7, 2025 at 6:31 PM
The visit highlighted the spirit of our project: connecting scientists across borders and disciplines to advance cutting-edge research together to uncover the mechanisms plants use to perceive water stress.
3/4
3/4
Reposted by Greg Madej
During this visit, Christine Ziegler @ziegler-lab-ur.bsky.social joined Malcolm Bennett in their lab at the University of Nottingham, while Eilon Shani @eilonshani.bsky.social also happened to be visiting the same research center — a perfect coincidence for a productive and friendly reunion!
2/4
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October 7, 2025 at 6:31 PM
During this visit, Christine Ziegler @ziegler-lab-ur.bsky.social joined Malcolm Bennett in their lab at the University of Nottingham, while Eilon Shani @eilonshani.bsky.social also happened to be visiting the same research center — a perfect coincidence for a productive and friendly reunion!
2/4
2/4
I've just commissioned a cryoEM new coffee mug in new design. To be fair, the mug is arguably the more critical piece of equipment for data collection. You try imaging a membrane proteins at 5 AM without caffeine. ☕🔬#cryoEM
October 9, 2025 at 3:40 AM
I've just commissioned a cryoEM new coffee mug in new design. To be fair, the mug is arguably the more critical piece of equipment for data collection. You try imaging a membrane proteins at 5 AM without caffeine. ☕🔬#cryoEM
MC 2025: We came, we saw, we won🏆 🏆! Amazing team on a fantastic time at the Microscopy Conference in Karlsruhe.
Get this: two of our posters won Poster Prizes! We're pretty sure it was our perfect blend of science and questionable doodles in the margins. @ziegler-lab-ur.bsky.social
Get this: two of our posters won Poster Prizes! We're pretty sure it was our perfect blend of science and questionable doodles in the margins. @ziegler-lab-ur.bsky.social
September 4, 2025 at 9:44 AM
MC 2025: We came, we saw, we won🏆 🏆! Amazing team on a fantastic time at the Microscopy Conference in Karlsruhe.
Get this: two of our posters won Poster Prizes! We're pretty sure it was our perfect blend of science and questionable doodles in the margins. @ziegler-lab-ur.bsky.social
Get this: two of our posters won Poster Prizes! We're pretty sure it was our perfect blend of science and questionable doodles in the margins. @ziegler-lab-ur.bsky.social
Ultrafast Almost Gold!
The Regensburg Center for Ultrafast Nanoscopy bio-section took second in the relay! Physics' reaction rates are attoseconds, but ours, Slower. Probably why "The Quantum Leapers" edged us out. Great fun and pretzels! @ziegler-lab-ur.bsky.social @katjaurbansky.bsky.social
The Regensburg Center for Ultrafast Nanoscopy bio-section took second in the relay! Physics' reaction rates are attoseconds, but ours, Slower. Probably why "The Quantum Leapers" edged us out. Great fun and pretzels! @ziegler-lab-ur.bsky.social @katjaurbansky.bsky.social
July 17, 2025 at 2:44 PM
Ultrafast Almost Gold!
The Regensburg Center for Ultrafast Nanoscopy bio-section took second in the relay! Physics' reaction rates are attoseconds, but ours, Slower. Probably why "The Quantum Leapers" edged us out. Great fun and pretzels! @ziegler-lab-ur.bsky.social @katjaurbansky.bsky.social
The Regensburg Center for Ultrafast Nanoscopy bio-section took second in the relay! Physics' reaction rates are attoseconds, but ours, Slower. Probably why "The Quantum Leapers" edged us out. Great fun and pretzels! @ziegler-lab-ur.bsky.social @katjaurbansky.bsky.social
So exciting … The publication where I had the privilege to contribute has been selected as an Editor's Choice. This recognition truly reflects everyone's hard work and dedication.
🔔 New issue! Articles on #Mycobacteria, gene regulation, and more:
🌐 Scientists' Forum: Recommendations by BioMed Alliance for Framework Programme 10
✳️ Editor's Choice: A novel gain-of-function PC2/PC1 heteromer
🔎 Review: pH homeostasis in Mycobacteria
➡️ bit.ly/3T41t9F
🌐 Scientists' Forum: Recommendations by BioMed Alliance for Framework Programme 10
✳️ Editor's Choice: A novel gain-of-function PC2/PC1 heteromer
🔎 Review: pH homeostasis in Mycobacteria
➡️ bit.ly/3T41t9F
June 26, 2025 at 3:51 PM
So exciting … The publication where I had the privilege to contribute has been selected as an Editor's Choice. This recognition truly reflects everyone's hard work and dedication.
Reposted by Greg Madej
Recently, our early-career researchers agreed on the value of organizing regular sessions for PhDs and PostDocs to explore key research topics in greater depth.
These sessions offer a space to understand the methods & techniques used across the 4 #Hydrosensing teams.
#science
These sessions offer a space to understand the methods & techniques used across the 4 #Hydrosensing teams.
#science
June 12, 2025 at 10:54 AM
Recently, our early-career researchers agreed on the value of organizing regular sessions for PhDs and PostDocs to explore key research topics in greater depth.
These sessions offer a space to understand the methods & techniques used across the 4 #Hydrosensing teams.
#science
These sessions offer a space to understand the methods & techniques used across the 4 #Hydrosensing teams.
#science
Reposted by Greg Madej
In the very 1st session this Tuesday, @greg-madej.bsky.social, from @uniregensburg.bsky.social @ziegler-lab-ur.bsky.social, presented how their expertise is applied within the project; specially the use of Cryo-EM in the study of membrane-embedded proteins.
🌐 www.uni-regensburg.de/biologie-vor...
🌐 www.uni-regensburg.de/biologie-vor...
June 12, 2025 at 10:54 AM
In the very 1st session this Tuesday, @greg-madej.bsky.social, from @uniregensburg.bsky.social @ziegler-lab-ur.bsky.social, presented how their expertise is applied within the project; specially the use of Cryo-EM in the study of membrane-embedded proteins.
🌐 www.uni-regensburg.de/biologie-vor...
🌐 www.uni-regensburg.de/biologie-vor...
Yesterday, through the tireless work of training runs, the support of my team, and the simple act of putting one foot in front of the other, we reached the finish line. The justice of completing what we set out to do, after the planning and the effort, has been served.
@katjaurbansky.bsky.social
@katjaurbansky.bsky.social
June 2, 2025 at 6:28 AM
Yesterday, through the tireless work of training runs, the support of my team, and the simple act of putting one foot in front of the other, we reached the finish line. The justice of completing what we set out to do, after the planning and the effort, has been served.
@katjaurbansky.bsky.social
@katjaurbansky.bsky.social
academic.oup.com/nar/article/...
Proud to have been a small part of the team behind the latest publication. It was a privilege to collaborate with such a talented group of researchers on this work. A massive congratulations to all the authors for this contribution to the field!
#RNA #cryoEM
Proud to have been a small part of the team behind the latest publication. It was a privilege to collaborate with such a talented group of researchers on this work. A massive congratulations to all the authors for this contribution to the field!
#RNA #cryoEM
A conserved nuclease facilitates environmental DNA uptake
Abstract. Bacteria acquire new traits through the uptake of genetic material from the environment, a process requiring DNA processing. However, the molecul
academic.oup.com
May 27, 2025 at 3:02 PM
academic.oup.com/nar/article/...
Proud to have been a small part of the team behind the latest publication. It was a privilege to collaborate with such a talented group of researchers on this work. A massive congratulations to all the authors for this contribution to the field!
#RNA #cryoEM
Proud to have been a small part of the team behind the latest publication. It was a privilege to collaborate with such a talented group of researchers on this work. A massive congratulations to all the authors for this contribution to the field!
#RNA #cryoEM
Here is an update on our recent activity.. febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
Mutations in polycystin-1 (PC1) or polycystin-2 (PC2) cause autosomal-dominant polycystic kidney disease (ADPKD). We generated a novel gain-of-function PC2/PC1 heteromeric ion channel by mutating por...
febs.onlinelibrary.wiley.com
May 12, 2025 at 11:42 AM
Here is an update on our recent activity.. febs.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Greg Madej
In @uniofnottingham.bsky.social ERC Hydrosensing members spent a few intense (and wardrobe-consistent 😅) days filming about research on root systems and how plants adapt to drought.
More footage for the documentary is being filmed at locations around the world in the coming year.
More footage for the documentary is being filmed at locations around the world in the coming year.
April 22, 2025 at 10:48 AM
In @uniofnottingham.bsky.social ERC Hydrosensing members spent a few intense (and wardrobe-consistent 😅) days filming about research on root systems and how plants adapt to drought.
More footage for the documentary is being filmed at locations around the world in the coming year.
More footage for the documentary is being filmed at locations around the world in the coming year.
Reposted by Greg Madej
We had the pleasure to contribute to this publication... It was a pleasure to be part of this effort. Congratulations to all authors! #cryoEM
@cmziegler.bsky.social
@greg-madej.bsky.social
pubs.acs.org/doi/full/10....
@cmziegler.bsky.social
@greg-madej.bsky.social
pubs.acs.org/doi/full/10....
Retinal to Retinal Energy Transfer in a Bistable Microbial Rhodopsin Dimer
Neorhodopsin (NeoR) is a newly discovered fungal bistable rhodopsin that reversibly photoswitches between UV- and near-IR absorbing states denoted NeoR367 and NeoR690, respectively. NeoR367 represents...
pubs.acs.org
April 22, 2025 at 9:18 AM
We had the pleasure to contribute to this publication... It was a pleasure to be part of this effort. Congratulations to all authors! #cryoEM
@cmziegler.bsky.social
@greg-madej.bsky.social
pubs.acs.org/doi/full/10....
@cmziegler.bsky.social
@greg-madej.bsky.social
pubs.acs.org/doi/full/10....
These were great days.. thank you all!
@hamannlab.bsky.social @eilonshani.bsky.social @sara-morghen.bsky.social @francesco-saffioti.bsky.social @katjaurbansky.bsky.social @wiebkehaeger.bsky.social @michaelaticha.bsky.social @hydrosensing.bsky.social @hydrophotonics.bsky.social
@hamannlab.bsky.social @eilonshani.bsky.social @sara-morghen.bsky.social @francesco-saffioti.bsky.social @katjaurbansky.bsky.social @wiebkehaeger.bsky.social @michaelaticha.bsky.social @hydrosensing.bsky.social @hydrophotonics.bsky.social
Just wanted to send a massive THANK YOU to everyone who joined our #HydroSensing meeting!
Great energy & insights. Let's keep the collaboration flowing!
A special shout-out to our guest speakers who sparkedfascinating dialogues. Your contributions were invaluable!
@hydrosensing.bsky.social #Plant
Great energy & insights. Let's keep the collaboration flowing!
A special shout-out to our guest speakers who sparkedfascinating dialogues. Your contributions were invaluable!
@hydrosensing.bsky.social #Plant
April 17, 2025 at 12:22 PM
Reposted by Greg Madej
First images coming soon 🤩
#JEOL CRYO ARM™ 200 #CryoEM installed at the Institute Genetics & Development of Rennes.
First installation of this type of instrument in France and incorporates the latest technologies in cryo contrast enhancement and dual-axis #tomography.
We wish IGDR success with their future research projects.
First installation of this type of instrument in France and incorporates the latest technologies in cryo contrast enhancement and dual-axis #tomography.
We wish IGDR success with their future research projects.
April 17, 2025 at 5:53 AM
First images coming soon 🤩
#HydroSensing Synergy Group - your fascinating talks last week completely watered the seeds of curiosity in my brain 😉. Prepare to see the photographic evidence of my descent into macroscale hydrosensing madness! I'm pretty sure my leafy friends 🌱 are judging my overly enthusiastic note-taking.
April 15, 2025 at 3:45 PM
#HydroSensing Synergy Group - your fascinating talks last week completely watered the seeds of curiosity in my brain 😉. Prepare to see the photographic evidence of my descent into macroscale hydrosensing madness! I'm pretty sure my leafy friends 🌱 are judging my overly enthusiastic note-taking.
We are fascinated by how our leafy friends 🌱 feel the subtle shifts in soil moisture 💦 Last week we hydrated your minds and cultivated connections at our #erc meeting focusing on the captivating world of #Plant #HydroSensing 🧩@hydrosensing.bsky.social @hydrophotonics.bsky.social
April 14, 2025 at 6:20 PM
We are fascinated by how our leafy friends 🌱 feel the subtle shifts in soil moisture 💦 Last week we hydrated your minds and cultivated connections at our #erc meeting focusing on the captivating world of #Plant #HydroSensing 🧩@hydrosensing.bsky.social @hydrophotonics.bsky.social
Reposted by Greg Madej
Exciting ERC synergy project meeting in Regensburg 😊@hydrosensing.bsky.social @ntnudiscovery.bsky.social @uniofnottingham.bsky.social @uniregensburg.bsky.social
April 11, 2025 at 8:30 AM
Exciting ERC synergy project meeting in Regensburg 😊@hydrosensing.bsky.social @ntnudiscovery.bsky.social @uniofnottingham.bsky.social @uniregensburg.bsky.social
After our annual #HydroSensing meeting in Regensburg, we went for a hike.. of course with a subsequent data collection and data processing demonstration 😁 #Plant #cryoEM
April 13, 2025 at 2:29 PM
After our annual #HydroSensing meeting in Regensburg, we went for a hike.. of course with a subsequent data collection and data processing demonstration 😁 #Plant #cryoEM