Gwen Knight
@gmknght.bsky.social
Prof of AMR research at London School of Hygiene and Tropical Medicine
Reposted by Gwen Knight
Join us for LSHTM’s Equity in AMR Action seminar, which explores how equity influences responses to AMR.
Speakers will share their work from the WHO, LSE, and the Global Strategy Lab.
📅 12 Dec
⏲️ 13:00 GMT
Check the event details 👇
www.lshtm.ac.uk/newsevents/e...
Speakers will share their work from the WHO, LSE, and the Global Strategy Lab.
📅 12 Dec
⏲️ 13:00 GMT
Check the event details 👇
www.lshtm.ac.uk/newsevents/e...
Equity in AMR Action | LSHTM
In 2025, the Network’s seminar series invites 2-3 speakers for each event to present their work on a particular theme around prioritisation. This fourth seminar of the series presents ‘Equity in AMR
www.lshtm.ac.uk
November 24, 2025 at 2:41 PM
Join us for LSHTM’s Equity in AMR Action seminar, which explores how equity influences responses to AMR.
Speakers will share their work from the WHO, LSE, and the Global Strategy Lab.
📅 12 Dec
⏲️ 13:00 GMT
Check the event details 👇
www.lshtm.ac.uk/newsevents/e...
Speakers will share their work from the WHO, LSE, and the Global Strategy Lab.
📅 12 Dec
⏲️ 13:00 GMT
Check the event details 👇
www.lshtm.ac.uk/newsevents/e...
Reposted by Gwen Knight
#Klebsiella infections are a serious & growing #PublicHealth threat
For #AntimicrobialAwarenessWeek, @josebengoechea.bsky.social discusses the dangers of bacterial infections, antimicrobial resistance & the global efforts to tackle it. @lshtmamrcentre.bsky.social
www.lshtm.ac.uk/newsevents/e...
For #AntimicrobialAwarenessWeek, @josebengoechea.bsky.social discusses the dangers of bacterial infections, antimicrobial resistance & the global efforts to tackle it. @lshtmamrcentre.bsky.social
www.lshtm.ac.uk/newsevents/e...
November 20, 2025 at 4:05 PM
#Klebsiella infections are a serious & growing #PublicHealth threat
For #AntimicrobialAwarenessWeek, @josebengoechea.bsky.social discusses the dangers of bacterial infections, antimicrobial resistance & the global efforts to tackle it. @lshtmamrcentre.bsky.social
www.lshtm.ac.uk/newsevents/e...
For #AntimicrobialAwarenessWeek, @josebengoechea.bsky.social discusses the dangers of bacterial infections, antimicrobial resistance & the global efforts to tackle it. @lshtmamrcentre.bsky.social
www.lshtm.ac.uk/newsevents/e...
Reposted by Gwen Knight
All are welcome to join the Gender Equity in TB Working Group today at 12:30 in Room B4B @theunion.org! We'll share updates on working group activities and host a panel discussion on progress to date and ways forward to ensure an equitable and inclusive #TB response.
November 20, 2025 at 9:06 AM
All are welcome to join the Gender Equity in TB Working Group today at 12:30 in Room B4B @theunion.org! We'll share updates on working group activities and host a panel discussion on progress to date and ways forward to ensure an equitable and inclusive #TB response.
Reposted by Gwen Knight
#AMR #Klebsiella cause >100,000 neonatal deaths globally each year.
Our new preprint shows more than half of #Klebsiella pneumoniae neonatal sepsis cases in African and South Asian are nosocomial, acquired through transmission in neonatal units. #WAAW
doi.org/10.1101/2025...
Our new preprint shows more than half of #Klebsiella pneumoniae neonatal sepsis cases in African and South Asian are nosocomial, acquired through transmission in neonatal units. #WAAW
doi.org/10.1101/2025...
![figure showing estimated proportion of cases in clusters, for each site. range from 0.04 to 0.93, mean estimate in random effects model is 0.57 [0.46,0.68]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:q5nky4heg5sfix4get4zh2pw/bafkreibshmuvkuafxwd2uk3r42ss6ma2dhmaidbysgvufnbkbv5cn4guai@jpeg)
November 19, 2025 at 3:43 PM
#AMR #Klebsiella cause >100,000 neonatal deaths globally each year.
Our new preprint shows more than half of #Klebsiella pneumoniae neonatal sepsis cases in African and South Asian are nosocomial, acquired through transmission in neonatal units. #WAAW
doi.org/10.1101/2025...
Our new preprint shows more than half of #Klebsiella pneumoniae neonatal sepsis cases in African and South Asian are nosocomial, acquired through transmission in neonatal units. #WAAW
doi.org/10.1101/2025...
Why is the
only statistical difference in resistant BSI by sex
in the 15 to 44 age group
where resistance was higher in females
(21.4% vs 18.9%, 8.5 vs 5.5 per 100,000 population).....?
👩💻🤔 latest #ESPAUR report on AMR just out!
only statistical difference in resistant BSI by sex
in the 15 to 44 age group
where resistance was higher in females
(21.4% vs 18.9%, 8.5 vs 5.5 per 100,000 population).....?
👩💻🤔 latest #ESPAUR report on AMR just out!
PUBLISHED: The 2023-24 English surveillance programme for antimicrobial utilisation and resistance (#ESPAUR) report www.gov.uk/government/p...
Register to find out more about the findings in the report at the webinar we are hosting on 20th November: antibioticguardian.com/Meetings/esp...
Register to find out more about the findings in the report at the webinar we are hosting on 20th November: antibioticguardian.com/Meetings/esp...
November 19, 2025 at 3:00 PM
Why is the
only statistical difference in resistant BSI by sex
in the 15 to 44 age group
where resistance was higher in females
(21.4% vs 18.9%, 8.5 vs 5.5 per 100,000 population).....?
👩💻🤔 latest #ESPAUR report on AMR just out!
only statistical difference in resistant BSI by sex
in the 15 to 44 age group
where resistance was higher in females
(21.4% vs 18.9%, 8.5 vs 5.5 per 100,000 population).....?
👩💻🤔 latest #ESPAUR report on AMR just out!
Reposted by Gwen Knight
Ahead of #WAAW2025, learn how our researchers are tackling AMR across 30 countries globally, spanning biology, clinical science, policy, modelling, and social sciences.
Stay updated on our research, insights, & AMR action.
Sign up for our newsletter: bit.ly/3X0SvvO
Stay updated on our research, insights, & AMR action.
Sign up for our newsletter: bit.ly/3X0SvvO
November 17, 2025 at 4:01 PM
Ahead of #WAAW2025, learn how our researchers are tackling AMR across 30 countries globally, spanning biology, clinical science, policy, modelling, and social sciences.
Stay updated on our research, insights, & AMR action.
Sign up for our newsletter: bit.ly/3X0SvvO
Stay updated on our research, insights, & AMR action.
Sign up for our newsletter: bit.ly/3X0SvvO
Reposted by Gwen Knight
London interdisciplinary #PhD position now open with myself, @sergemostowylab.bsky.social, & @gmknght.bsky.social on #phage -bacteria-host immune dynamics for WHO priority bacterial pathogens #Klebsiella, #Shigella, and #Staph. Combines cellular microbiology, genomics, & mathematical modelling.
2026-27 Project (Dyson & Mostowy & Knight) - MRC London Intercollegiate Doctoral Training Partnership Studentships
PHACTS: Unravelling PHAge-baCTeria-host immune dynamicS to inform phage therapy SUPERVISORY TEAM Supervisor Dr Zoe Dyson...
mrc-lid.lshtm.ac.uk
November 13, 2025 at 11:11 AM
London interdisciplinary #PhD position now open with myself, @sergemostowylab.bsky.social, & @gmknght.bsky.social on #phage -bacteria-host immune dynamics for WHO priority bacterial pathogens #Klebsiella, #Shigella, and #Staph. Combines cellular microbiology, genomics, & mathematical modelling.
Excited to say that we have a PhD project out on our age-sex research - looking at combinations of #AMR. With the fabulous @jodi-lindsay.bsky.social and Lanre Edun! Do get in touch for more information!
mrc-lid.lshtm.ac.uk/2026-27-proj...
mrc-lid.lshtm.ac.uk/2026-27-proj...
Projects - MRC London Intercollegiate Doctoral Training Partnership Studentships
2026-27 MRC LID POTENTIAL RESEARCH PROJECTS MRC LID is offering 40 distinct potential projects for...
mrc-lid.lshtm.ac.uk
November 10, 2025 at 4:05 PM
Excited to say that we have a PhD project out on our age-sex research - looking at combinations of #AMR. With the fabulous @jodi-lindsay.bsky.social and Lanre Edun! Do get in touch for more information!
mrc-lid.lshtm.ac.uk/2026-27-proj...
mrc-lid.lshtm.ac.uk/2026-27-proj...
Reposted by Gwen Knight
Drug-resistant infections in Europe set to rise as populations age, study suggests
@gmknght.bsky.social & Catrin Moore explain understanding demographics & infection trends will help design more effective ways of controlling & preventing drug-resistant infections.
www.lshtm.ac.uk/newsevents/n...
@gmknght.bsky.social & Catrin Moore explain understanding demographics & infection trends will help design more effective ways of controlling & preventing drug-resistant infections.
www.lshtm.ac.uk/newsevents/n...
November 5, 2025 at 11:54 AM
Drug-resistant infections in Europe set to rise as populations age, study suggests
@gmknght.bsky.social & Catrin Moore explain understanding demographics & infection trends will help design more effective ways of controlling & preventing drug-resistant infections.
www.lshtm.ac.uk/newsevents/n...
@gmknght.bsky.social & Catrin Moore explain understanding demographics & infection trends will help design more effective ways of controlling & preventing drug-resistant infections.
www.lshtm.ac.uk/newsevents/n...
How will population shifts affect the future burden of #AMR? 👶👩🦳 🧫
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
Combining demographic shifts with age-based resistance prevalence to estimate future antimicrobial resistance burden in Europe and implications for targets: A modelling study
Author summary Why was this study done? Infections caused by bacteria that are resistant to antibiotics are a major and growing threat to public health. Older adults and men are at higher risk of...
doi.org
November 5, 2025 at 12:06 PM
How will population shifts affect the future burden of #AMR? 👶👩🦳 🧫
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics.
doi.org/10.1371/jour...
Reposted by Gwen Knight
Agata Pacho and I published an article on self care and UTIs/AMR this week! In Sociology of Health and Illness:
onlinelibrary.wiley.com/doi/10.1111/.... @lshtmamrcentre.bsky.social
onlinelibrary.wiley.com/doi/10.1111/.... @lshtmamrcentre.bsky.social
onlinelibrary.wiley.com
October 24, 2025 at 2:19 PM
Agata Pacho and I published an article on self care and UTIs/AMR this week! In Sociology of Health and Illness:
onlinelibrary.wiley.com/doi/10.1111/.... @lshtmamrcentre.bsky.social
onlinelibrary.wiley.com/doi/10.1111/.... @lshtmamrcentre.bsky.social
Reposted by Gwen Knight
PhD opportunity in my lab: exploring how commensals and pathogens build biofilm communities on endotracheal (ventilator) tubes. Microbial ecology, medical microbiology and fancy imaging! Co-supervised with the fabulous Saskia Bakker and Jeremy Webb warwick.ac.uk/fac/cross_fa... #MicroSky
Dr Freya Harrison
Dr Freya Harrison
warwick.ac.uk
October 15, 2025 at 8:09 PM
PhD opportunity in my lab: exploring how commensals and pathogens build biofilm communities on endotracheal (ventilator) tubes. Microbial ecology, medical microbiology and fancy imaging! Co-supervised with the fabulous Saskia Bakker and Jeremy Webb warwick.ac.uk/fac/cross_fa... #MicroSky
Reposted by Gwen Knight
🚀 Exciting news!
Our Centre Director @katholt.bsky.social will be speaking at #AMR2026 on “AMRrules: Interpretive Standards for AMR Genotypes.”
Don’t miss her insights🧬✨
📅 23–25 March 2026
🔗 bit.ly/3SWzJUm
#MicroSky #AMR #Genomics
Our Centre Director @katholt.bsky.social will be speaking at #AMR2026 on “AMRrules: Interpretive Standards for AMR Genotypes.”
Don’t miss her insights🧬✨
📅 23–25 March 2026
🔗 bit.ly/3SWzJUm
#MicroSky #AMR #Genomics
October 14, 2025 at 1:24 PM
🚀 Exciting news!
Our Centre Director @katholt.bsky.social will be speaking at #AMR2026 on “AMRrules: Interpretive Standards for AMR Genotypes.”
Don’t miss her insights🧬✨
📅 23–25 March 2026
🔗 bit.ly/3SWzJUm
#MicroSky #AMR #Genomics
Our Centre Director @katholt.bsky.social will be speaking at #AMR2026 on “AMRrules: Interpretive Standards for AMR Genotypes.”
Don’t miss her insights🧬✨
📅 23–25 March 2026
🔗 bit.ly/3SWzJUm
#MicroSky #AMR #Genomics
Reposted by Gwen Knight
Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries.
bit.ly/4nbV492
bit.ly/4nbV492
A global analysis of patterns of tuberculosis exposure and transmission
Tuberculosis (TB) is a major public health concern and the leading infectious cause of mortality globally. The disease exhibits strong prevalence patterns by age and sex, but the implications of these...
www.medrxiv.org
October 12, 2025 at 12:51 PM
Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries.
bit.ly/4nbV492
bit.ly/4nbV492
Reposted by Gwen Knight
I don't want to seem too cynical, but I wrote this 4 years ago: "...it will come as little surprise if a similar report in a year's time will be almost indistinguishable from the current version."
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Antimicrobial resistance: plus ça change
This issue marks the first anniversary of The Lancet Microbe. This has been a year
of profound change during which the world has experienced the most consequential infectious
disease outbreak of the p...
www.thelancet.com
October 14, 2025 at 9:18 AM
I don't want to seem too cynical, but I wrote this 4 years ago: "...it will come as little surprise if a similar report in a year's time will be almost indistinguishable from the current version."
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Great to see accounting for age and sex in the #AMR estimates from the latest WHO #AMR global burden report out today! www.who.int/publications...
Global antibiotic resistance surveillance report 2025
This new WHO report presents a global analysis of antibiotic resistance prevalence and trends, drawing on more than 23 million bacteriologically confirmed cases of bloodstream infections, urinary trac...
www.who.int
October 13, 2025 at 11:27 AM
Great to see accounting for age and sex in the #AMR estimates from the latest WHO #AMR global burden report out today! www.who.int/publications...
Reposted by Gwen Knight
In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...
Do no harm - re-evaluating the risks of overtreatment in community-wide tuberculosis screening
Background Community-wide screening is a crucial strategy to end tuberculosis (TB), but a common concern is potential harm from overtreatment following false positive diagnoses. However, current refer...
www.medrxiv.org
October 7, 2025 at 9:17 AM
In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...
Reposted by Gwen Knight
Sepsis claims a life every 3 seconds.
Ahead of #WorldSepsisDay, @jhenryc.bsky.social @lshtm.bsky.social shares 5 Facts × 5 Actions to tackle sepsis 🩺 & AMR 🦠—from empowering frontline workers 👩⚕️ to strengthening diagnostics 🔍 & integrating national response plans 🌍
👉 bit.ly/3Vh4NiG
Ahead of #WorldSepsisDay, @jhenryc.bsky.social @lshtm.bsky.social shares 5 Facts × 5 Actions to tackle sepsis 🩺 & AMR 🦠—from empowering frontline workers 👩⚕️ to strengthening diagnostics 🔍 & integrating national response plans 🌍
👉 bit.ly/3Vh4NiG
World Sepsis Day 2025: 5 Facts x 5 Actions to tackle sepsis and antimicrobial
World Sepsis Day 2025: 5 Facts x 5 Actions to tackle sepsis and antimicrobial resistance | LSHTM
bit.ly
September 12, 2025 at 10:14 AM
Sepsis claims a life every 3 seconds.
Ahead of #WorldSepsisDay, @jhenryc.bsky.social @lshtm.bsky.social shares 5 Facts × 5 Actions to tackle sepsis 🩺 & AMR 🦠—from empowering frontline workers 👩⚕️ to strengthening diagnostics 🔍 & integrating national response plans 🌍
👉 bit.ly/3Vh4NiG
Ahead of #WorldSepsisDay, @jhenryc.bsky.social @lshtm.bsky.social shares 5 Facts × 5 Actions to tackle sepsis 🩺 & AMR 🦠—from empowering frontline workers 👩⚕️ to strengthening diagnostics 🔍 & integrating national response plans 🌍
👉 bit.ly/3Vh4NiG
Reposted by Gwen Knight
Congratulations to Jody Phelan for receiving the prestigious @esmyco.bsky.social Gertrud Meissner Award for his groundbreaking work on drug resistant tuberculosis 👏🌍
Read more 👉 bit.ly/4mfGDjW
Read more 👉 bit.ly/4mfGDjW
Jody Phelan receives Gertrud Meissner Award | LSHTM
Jody Phelan receives Gertrud Meissner Award | LSHTM
bit.ly
July 28, 2025 at 2:12 PM
Congratulations to Jody Phelan for receiving the prestigious @esmyco.bsky.social Gertrud Meissner Award for his groundbreaking work on drug resistant tuberculosis 👏🌍
Read more 👉 bit.ly/4mfGDjW
Read more 👉 bit.ly/4mfGDjW
Unfortunately, we're going to have to reschedule this talk - if you have a free hour then do go back and check our some of our past seminars across the #AMR disciplines!
www.lshtm.ac.uk/research/cen...
www.lshtm.ac.uk/research/cen...
July 9, 2025 at 9:26 AM
Unfortunately, we're going to have to reschedule this talk - if you have a free hour then do go back and check our some of our past seminars across the #AMR disciplines!
www.lshtm.ac.uk/research/cen...
www.lshtm.ac.uk/research/cen...
Really looking forward to hear this high level overview of #AMR policy from a great female scientist!
Tomorrow - UK - lunch time 👩💻
Tomorrow - UK - lunch time 👩💻
🎙️ Join Prof Dame Sally Davies, for an insightful seminar on global action against AMR.
In this seminar, she will share updates on the UN High-Level AMR agenda, the evidence panel & what’s next for global policy.
📅 9 July 2025
🕰️ 13:00 BST
📍 Online
🔗 bit.ly/4kVSVgP
In this seminar, she will share updates on the UN High-Level AMR agenda, the evidence panel & what’s next for global policy.
📅 9 July 2025
🕰️ 13:00 BST
📍 Online
🔗 bit.ly/4kVSVgP
July 8, 2025 at 2:10 PM
Really looking forward to hear this high level overview of #AMR policy from a great female scientist!
Tomorrow - UK - lunch time 👩💻
Tomorrow - UK - lunch time 👩💻
A Friday reminder of this talk next Wednesday.
I'm looking forward to welcoming our students to the @lshtm.bsky.social @lshtmamrcentre.bsky.social #AMR short course and then having this seminar from Prof Dame Sally Davies!
I'm looking forward to welcoming our students to the @lshtm.bsky.social @lshtmamrcentre.bsky.social #AMR short course and then having this seminar from Prof Dame Sally Davies!
Very excited for this event on the 9th July!
It's part of our #AMR short course but open to everyone as it's online. Do join in and here what the amazing Prof Dame Sally Davies has to stay on the current status of global action on #AMR! @lshtmamrcentre.bsky.social
It's part of our #AMR short course but open to everyone as it's online. Do join in and here what the amazing Prof Dame Sally Davies has to stay on the current status of global action on #AMR! @lshtmamrcentre.bsky.social
🎙️ Join Prof Dame Sally Davies, for an insightful seminar on global action against AMR.
In this seminar, she will share updates on the UN High-Level AMR agenda, the evidence panel & what’s next for global policy.
📅 9 July 2025
🕰️ 13:00 BST
📍 Online
🔗 bit.ly/4kVSVgP
In this seminar, she will share updates on the UN High-Level AMR agenda, the evidence panel & what’s next for global policy.
📅 9 July 2025
🕰️ 13:00 BST
📍 Online
🔗 bit.ly/4kVSVgP
July 4, 2025 at 3:19 PM
A Friday reminder of this talk next Wednesday.
I'm looking forward to welcoming our students to the @lshtm.bsky.social @lshtmamrcentre.bsky.social #AMR short course and then having this seminar from Prof Dame Sally Davies!
I'm looking forward to welcoming our students to the @lshtm.bsky.social @lshtmamrcentre.bsky.social #AMR short course and then having this seminar from Prof Dame Sally Davies!
Reposted by Gwen Knight
In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials.
doi.org/10.1016/S221...
@lshtm-tbmod.bsky.social @tb-lshtm.bsky.social
doi.org/10.1016/S221...
@lshtm-tbmod.bsky.social @tb-lshtm.bsky.social
July 4, 2025 at 11:25 AM
In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials.
doi.org/10.1016/S221...
@lshtm-tbmod.bsky.social @tb-lshtm.bsky.social
doi.org/10.1016/S221...
@lshtm-tbmod.bsky.social @tb-lshtm.bsky.social
Reposted by Gwen Knight
LSHTM's Director writes to UK Government about #Gaza public health catastrophe
Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster:
👉 www.lshtm.ac.uk/newsevents/n...
Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster:
👉 www.lshtm.ac.uk/newsevents/n...
June 20, 2025 at 1:32 PM
LSHTM's Director writes to UK Government about #Gaza public health catastrophe
Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster:
👉 www.lshtm.ac.uk/newsevents/n...
Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster:
👉 www.lshtm.ac.uk/newsevents/n...