Girish Kale
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girishkalephd.bsky.social
Girish Kale
@girishkalephd.bsky.social
240 followers 480 following 18 posts
Cell and Developmental biologist, expanding into ecological thinking and evolutionary comparative approaches. Interested in how elevated temperatures affect embryo survival, focusing on pre-gastrulation development, in the context of global warming🌡
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girishkalephd.bsky.social
Girish Kale @girishkalephd.bsky.social · Nov 22
Our recent preprint on how elevated temperatures affect early embryo development. We are using fly embryos to address this fundamental question, and seeing mitotic defects, which can be rescued to improve embryo survival.

doi.org/10.1101/2023...
Elevated temperature fatally disrupts nuclear divisions in the early Drosophila embryo
Temperature variations can challenge animal survival, with different life cycle stages presenting distinct vulnerabilities to elevated temperature. Here, embryonic development is known to be especiall...
doi.org
girishkalephd.bsky.social
Thanks @amjeve.bsky.social for the invitation to write this perspective in the 'In Preprints' series in @dev-journal.bsky.social .

What's the downside of acclimation to low temperature? Turns out you will perform worse in heat shock.
doi.org/10.1242/dev....
In preprints: multiomics of low temperature acclimation in the era of intensifying temperature fluctuations
In a warming world, all life forms – endotherms and ectotherms alike – are finding their homeostasis being challenged. The environmental change is challenging at all stages of life. How different orga...
doi.org
October 20, 2025 at 5:24 PM
Reposted by Girish Kale
vgzt2021.bsky.social
We are excited to announce the second Western VGZT of Season 7!

🗓️Thursday, October 16th
⏰9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

Our speakers:
👉 Hidenobu Miyazawa (on X: @HidenobuAnzo)
👉 Girish Kale (@girishkalephd.bsky.social)

See you next week! 👋
October 10, 2025 at 9:51 AM
girishkalephd.bsky.social
Join the VGZT session next Thursday, with a seminar also from yours truly :)
vgzt2021.bsky.social Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · Oct 10
We are excited to announce the second Western VGZT of Season 7!

🗓️Thursday, October 16th
⏰9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

Our speakers:
👉 Hidenobu Miyazawa (on X: @HidenobuAnzo)
👉 Girish Kale (@girishkalephd.bsky.social)

See you next week! 👋
October 10, 2025 at 10:29 AM
Reposted by Girish Kale
jamesbriscoe.bsky.social
The @crick.ac.uk is recruiting Early Career Group Leaders

- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology

Deadline 27 Nov

www.crick.ac.uk/careers-stud...
Early career group leaders
We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.
www.crick.ac.uk
October 10, 2025 at 8:20 AM
Reposted by Girish Kale
jytinevez.bsky.social
Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...
Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA
Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...
forum.image.sc
October 7, 2025 at 12:39 PM
Reposted by Girish Kale
vgzt2021.bsky.social
Dear VGZT enthusiasts,
Do you—or someone in your lab—work on exciting developmental biology research? Showcase it at VGZT, a global online seminar series connecting developmental biologists across all career stages. Apply here: www.tinyurl.com/VGZT-Nomination
VGZT Season 7 - Nomination
Virtual Gastrulation Zoom Talks (VGZT) is an opportunity to share your science with an engaged, international audience of developmental biologists. Running from October 2025 to July 2026, this online ...
www.tinyurl.com
October 6, 2025 at 8:12 AM
Reposted by Girish Kale
flybase.bsky.social
There's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase...
We express enormous gratitude to the people, labs, groups, and foundations who have already helped us.
#FlyBase #Drosophila
FlyBase Update – October 2025 The termination of the NIH/NHGRI FlyBase grant has placed the long-term sustainability of FlyBase at risk. However, thanks to the generous support of several key individuals and institutions, we are pleased to announce that FlyBase will remain operational through the coming year. We extend our deepest gratitude to Yukiko Yamashita, Cassandra Extavour, Hugo Bellen, Thom Kaufman, the Genetics Society of America / Drosophila Board, the Bloomington Drosophila Stock Center, an anonymous donor and the Wellcome Trust. We are especially thankful for a generous gift from Seemay Chou, Jed McCaleb, and The Navigation Fund. We also greatly appreciate the continued support from the broader Drosophila community – your donations and service fees have been vital in helping us stay afloat. Special thanks also go to Jessica Manning for her tireless administrative work at Harvard, to Ruth Lehmann, Hugo Bellen, and Paul Sternberg for advice and efforts, and to the Board of the European Drosophila Society for all their efforts. Sadly, we must also share that several long-standing FlyBase team members have recently moved on. We are immensely grateful to Susan Russo-Gelbart, Lynn Crosby, Gil dos Santos, Kris Broll, Victoria Jenkins, and TyAnna Lovato for their many years of dedicated service and contributions to FlyBase. Looking ahead, ensuring FlyBase’s sustainability beyond the next year – and successfully integrating with the Alliance – will require new funding sources. We kindly ask for your continued support: • European labs: Please consider contributing to the Cambridge, U.K. FlyBase group • U.S. and other non-European labs: Please consider contributing to the U.S. FlyBase groups • Both U.K. and U.S. FlyBase are working diligently to establish an invoicing system. We appreciate your continued patience. For more information on how to support us, please visit: Contribute to FlyBase wiki page https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase
October 3, 2025 at 6:19 PM
Reposted by Girish Kale
vgzt2021.bsky.social
We are excited to announce the first Western VGZT of Season 7! 🎉

🗓️ Thursday, October 2nd
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

Our speakers:

👉 Antonia Weberling (@a-weberling.bsky.social)

👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)
September 25, 2025 at 2:17 PM
Reposted by Girish Kale
paveltomancak.bsky.social
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:22 AM
Reposted by Girish Kale
yuchiunwang.bsky.social
Tissue 'tectonic' collision is detrimental, but flies found two distinct solutions! Gratifying and grateful to be included in this collective effort, w/ Steffen Lemke, to crack the (or 'a') code of #cephalicfurrow, now out in @nature.com, all with @paveltomancak.bsky.social at the helm. (1/9)
September 4, 2025 at 5:18 PM
Reposted by Girish Kale
prelights.bsky.social
🚨 New call for preLighters!🚨

Help us highlight the most exciting biological #preprints. Share your insights, build your profile, and be part of a supportive community! 🌍

Interested? Apply today & help shape the future of science publishing! 📢

More info: prelights.biologists.com/news/join-th...
September 1, 2025 at 8:59 AM
Reposted by Girish Kale
peiferlabunc.bsky.social
The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share
Dear Fly Community, In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled. The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC). Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options. To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum). To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu… https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase Our immediate goals are: 1. To maintain core curation activities and keep the FlyBase website online 2. To complete integration with the Alliance of Genome Resources (The Alliance). Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data. At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise. Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028. We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide. Sincerely, The FlyBase Team
August 23, 2025 at 12:18 PM
Reposted by Girish Kale
biologists.bsky.social
July in preprints, the CellBio edition, is out now on the preLights website.

Thanks to Girish Kale, Matthew Davies, Barbora Knotkova and Sristilekha Nath for their contributions.

Have a look:

prelights.biologists.com/prelists/jul...

#PrePrints #Publishing #Biology #Research #CellBio #PreLights
July in preprints - the CellBio edition - preLights
Related posts
prelights.biologists.com
August 20, 2025 at 1:07 PM
Reposted by Girish Kale
flybase.bsky.social
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
FlyBase:Contribute to FlyBase - FlyBase Wiki
wiki.flybase.org
August 15, 2025 at 12:45 PM
girishkalephd.bsky.social
Please support FlyBase however you can. The importance of @flybase.bsky.social to biology research mirrors what flies to our ecosystems. You can throw money (if you have it) at only one of these problems to go away, but I guess that's a start.
hansonmark.bsky.social Mark A. Hanson @hansonmark.bsky.social · Aug 14
A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate.

www.philanthropy.cam.ac.uk/give-to-camb...
August 14, 2025 at 9:14 AM
Reposted by Girish Kale
prelights.bsky.social
‪July in #Preprints – the CellBio edition - is out.

Thanks to @girishkalephd.bsky.social, Matthew Davies, Barbora Knotkova, and Sristilekha Nath for their contributions.

Have a look! 🍵
July in preprints - the CellBio edition - preLights
prelights.biologists.com
August 7, 2025 at 10:27 AM
Reposted by Girish Kale
the-node.bsky.social
Would you like to be the Node’s new Community Manager?

If you're interested in #SciComm and passionate about #DevBio, apply to join the @dev-journal.bsky.social & @biologists.bsky.social team.

Find out more about what the role entails: bit.ly/4otQ2GL

#JobOpportunity
Community Manager, the Node - the Node
The Company of Biologists and its journal Development are seeking to appoint a new Community Manager to run its successful community website ‘the Node’ and the journal’s social media activities. Launc...
thenode.biologists.com
August 5, 2025 at 2:34 PM
Reposted by Girish Kale
katiemillar.bsky.social
I can't believe this only ended up getting 3,590 supporters when it needed 10,000; it was a sad day. This has unlocked a new fixation, and I will campaign to get this reopened... #Drosophila #Tribolium #CoolScience #FruitFlies

beta.ideas.lego.com/product-idea...
Arthropod Model Organisms | LEGO® Ideas
Scientists have learned a great deal about biology from a handful of "model organisms" – animals with unique characteristics that make them excellent for labora…
beta.ideas.lego.com
July 14, 2025 at 9:45 PM
Reposted by Girish Kale
gomezjm-devmech.bsky.social
🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
July 15, 2025 at 2:12 PM
girishkalephd.bsky.social
Happening today!
vgzt2021.bsky.social Virtual Gastrulation Zoom Talks @vgzt2021.bsky.social · Jul 16
Slight change regarding our Western 🌙 KEYNOTE seminars!

This week, on

🗓️ Thursday, July 17
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

Charlene Guillot @charleneguillot.bsky.social will speak

And we will be back on Aug 07 for another seminar by @josh-brickman.bsky.social

Details 👇
July 17, 2025 at 8:41 AM
Reposted by Girish Kale
odedrechavi.bsky.social
@ethanewe.bsky.social is on the job market and you want him as your colleague! On top of everything that he already published he also has a few especially amazing papers in the works... (soon!)
snickclunk.bsky.social Teresa Lee @snickclunk.bsky.social · Jul 1
#worm25 is greatly missing the enthusiasm of @ethanewe.bsky.social at this meeting! He gave a great virtual talk this morning, featuring a hot-off-the-presses story from his postdoc in the Rechavi lab. 🤩
He's also applying for faculty jobs this cycle, so keep an eye out for his application! 🙌
July 2, 2025 at 6:44 AM
Reposted by Girish Kale
katherine-brown.bsky.social
Seconded. Ethan is one of @dev-journal.bsky.social's Pathway to Independence fellows this year, and - on top of his great research programme - has been super-active in the @prelights.bsky.social community.
odedrechavi.bsky.social Oded Rechavi @odedrechavi.bsky.social · Jul 2
@ethanewe.bsky.social is on the job market and you want him as your colleague! On top of everything that he already published he also has a few especially amazing papers in the works... (soon!)
snickclunk.bsky.social Teresa Lee @snickclunk.bsky.social · Jul 1
#worm25 is greatly missing the enthusiasm of @ethanewe.bsky.social at this meeting! He gave a great virtual talk this morning, featuring a hot-off-the-presses story from his postdoc in the Rechavi lab. 🤩
He's also applying for faculty jobs this cycle, so keep an eye out for his application! 🙌
July 3, 2025 at 1:49 PM
Reposted by Girish Kale
vgzt2021.bsky.social
Join us next week for our Western 🌙 KEYNOTE seminar:

🗓️ Thursday, July 17
⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET

Our speakers are:
Josh Brickman @josh-brickman.bsky.social

Charlene Guillot @charleneguillot.bsky.social

We are looking forward to this great season finale! 🥳
July 12, 2025 at 8:35 PM
Reposted by Girish Kale
vgzt2021.bsky.social
Join the VGZT Eastern KEYNOTE lecture ☀️☕ TOMORROW

🗓️ Wednesday July 09
⏰ 13:30 IST / 17:00 JST / 8:00 UTC / 10:00 CET

Featuring:
1) Maithreyi Narasimha
👉Positioning tissues during Drosophila morphogenesis

Jose Silva @josesilvalab.bsky.social
👉From founder cells to organogenesis-stage embryo model
July 8, 2025 at 10:54 AM
Reposted by Girish Kale
the-node.bsky.social
Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social ‬and @nikhil-mishra.bsky.social

📅Wed 9 July 15:00BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

#DevBio @dev-journal.bsky.social
Development presents... Wednesday 9 July 15:00 BST, chaired by Alex Eve. Talk 1: Lakshmi Balasubramaniam (Gurdon Institute) ‘Tissue spreading couples matrix remodelling during avian gastrulation’ Talk 2: André Dias (Universitat Pompeu Fabra) ‘Opposing Nodal and Wnt signalling activities govern the emergence of the mammalian body plan’ Talk 3: Nikhil Mishra (Institute of Science and Technology Austria) ‘Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo’
July 4, 2025 at 2:16 PM