John Newman, MD, PhD
@geriscidoc.bsky.social
Geriatrician and geroscientist at Buck Institute and UCSF Geriatrics. Views my own. #medsky #geronsky
Reposted by John Newman, MD, PhD
Another packed house today for Dr John Newman’s (@GeriSciDoc.bsky.social) talk on How to Be Your Own Geriatrician. To register for our upcoming seminar: How Did Our Bodies End Up This Way on Oct 1: buckinstitute.org/events/lblseminars
September 3, 2025 at 6:53 PM
Another packed house today for Dr John Newman’s (@GeriSciDoc.bsky.social) talk on How to Be Your Own Geriatrician. To register for our upcoming seminar: How Did Our Bodies End Up This Way on Oct 1: buckinstitute.org/events/lblseminars
Reposted by John Newman, MD, PhD
Today is a special day! It's our second BARI symposium at the de Young Museum in the beautiful Golden Gate Park.
April 14, 2025 at 4:10 PM
Today is a special day! It's our second BARI symposium at the de Young Museum in the beautiful Golden Gate Park.
Outstanding work, Emily! I'm so excited to see this cool story out! What a great example of "that's odd" being the most important words in science.
I could not be more excited to have our lab's first story online where we report our discovery that HDACs ~reverse~ their activity to ADD acyl groups to lysine! We found this for our favorite ketone body, BHB, but this pathway controls other lysine modifications too!🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reversible histone deacetylase activity catalyzes lysine acylation - Nature Chemical Biology
Tsusaka et al. discover that histone deacetylases, which are well known to remove protein modifications, such as lysine acetylation and β-hydroxybutyrylation, can also reverse their chemical activity ...
www.nature.com
March 31, 2025 at 1:55 PM
Outstanding work, Emily! I'm so excited to see this cool story out! What a great example of "that's odd" being the most important words in science.
Reposted by John Newman, MD, PhD
I could not be more excited to have our lab's first story online where we report our discovery that HDACs ~reverse~ their activity to ADD acyl groups to lysine! We found this for our favorite ketone body, BHB, but this pathway controls other lysine modifications too!🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reversible histone deacetylase activity catalyzes lysine acylation - Nature Chemical Biology
Tsusaka et al. discover that histone deacetylases, which are well known to remove protein modifications, such as lysine acetylation and β-hydroxybutyrylation, can also reverse their chemical activity ...
www.nature.com
March 26, 2025 at 2:02 PM
I could not be more excited to have our lab's first story online where we report our discovery that HDACs ~reverse~ their activity to ADD acyl groups to lysine! We found this for our favorite ketone body, BHB, but this pathway controls other lysine modifications too!🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by John Newman, MD, PhD
Come visit the Buck booth at North Bay Science Discovery Day at the Sonoma County Fairgrounds today! We’re in The Hall of Flowers. Booth 24. We’ve got some really cool experiments to check out! @northbayscience
March 8, 2025 at 8:37 PM
Come visit the Buck booth at North Bay Science Discovery Day at the Sonoma County Fairgrounds today! We’re in The Hall of Flowers. Booth 24. We’ve got some really cool experiments to check out! @northbayscience
We're kicking off an NIA-AGS symposium on the intersection of Alzheimer's disease and multiple chronic conditions - exactly the sort of interdisciplinary, un-siloed, patient-centered science that National Institute on Aging does so uniquely well! www.americangeriatrics.org/r13conference
INTERSECTION OF MULTIPLE CHRONIC CONDITIONS (MCCS) AND ALZHEIMER'S DISEASE AND ALZHEIMER'S DISEASE RELATED DEMENTIAS (AD/ADRD)
Intersection of Multiple Chronic Conditions (MCCs) and Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) (2025)
www.americangeriatrics.org
March 6, 2025 at 1:48 PM
We're kicking off an NIA-AGS symposium on the intersection of Alzheimer's disease and multiple chronic conditions - exactly the sort of interdisciplinary, un-siloed, patient-centered science that National Institute on Aging does so uniquely well! www.americangeriatrics.org/r13conference
Reposted by John Newman, MD, PhD
Learn how to be your own geriatrician! Buck was thrilled to partner with Vivalon this week providing valuable info to older adults on how to best advocate for themselves in a medical system that often lets them down. Kudos to Dr. John Newman! www.youtube.com/watch?v=-6A-... @geriscidoc.bsky.social
Learn How to Be Your Own Geriatrician - The Buck Institute for Research on Aging at Vivalon
YouTube video by Vivalon
www.youtube.com
February 28, 2025 at 8:50 PM
Learn how to be your own geriatrician! Buck was thrilled to partner with Vivalon this week providing valuable info to older adults on how to best advocate for themselves in a medical system that often lets them down. Kudos to Dr. John Newman! www.youtube.com/watch?v=-6A-... @geriscidoc.bsky.social
Reposted by John Newman, MD, PhD
Cuts to the VA research have been hard. I've lost colleagues, including one studying Veteran homelessness. But losing VA research hurts us all.
1/6
(I'm expressing my own views and not necessarily those of the VA or the US government.)
1/6
(I'm expressing my own views and not necessarily those of the VA or the US government.)
NIH cuts are getting the press, but VA research is getting slashed too. What do we lose when VA research goes away? Here's some greatest hits: The nicotine patch, invention of the cardiac pacemaker, first successful liver transplant, development of the CAT/CT scan
prospect.org/health/2025-...
prospect.org/health/2025-...
VA Research Funding Slashed
Though not as prominent as the NIH, VA researchers play a major role in advancing basic health science. Hundreds of projects have been cut.
prospect.org
February 26, 2025 at 2:26 AM
Cuts to the VA research have been hard. I've lost colleagues, including one studying Veteran homelessness. But losing VA research hurts us all.
1/6
(I'm expressing my own views and not necessarily those of the VA or the US government.)
1/6
(I'm expressing my own views and not necessarily those of the VA or the US government.)
Well done, Jade and @serogersmd.bsky.social! What a fantastic NIH-funded MSTAR project.
MSTAR student Jade Mulvey, Drs. Stephanie Rogers (@serogersmd.bsky.social), James Harrison, & team published in *Journal of Nursing Care Quality*: "Mobility Loss in Hospitalized Adults Predicts Poor Clinical Outcomes." Read more: https://buff.ly/4gMdxpr #geriatrics #nursing
Mobility Loss in Hospitalized Adults Predicts Poor Clinical ... : Journal of Nursing Care Quality
as used. Patients were categorized into 3 groups (gain, loss, no change in mobility) using the Johns Hopkins Highest Level of Mobility (JH-HLM) scores. The association between mobility loss and falls...
buff.ly
February 24, 2025 at 10:12 PM
Well done, Jade and @serogersmd.bsky.social! What a fantastic NIH-funded MSTAR project.
Reposted by John Newman, MD, PhD
📢 Save the date! The 2025 California Academic Geriatrics Institutions (CAGI) Conference is happening May 30 at UC Irvine. Join geriatrics professionals from across CA to connect & collaborate. Coordinated with support from Drs. Todd James (@Geri_IPE) & @susanschneiderucsf.bsky.social! #CAGI2025
February 14, 2025 at 6:28 PM
📢 Save the date! The 2025 California Academic Geriatrics Institutions (CAGI) Conference is happening May 30 at UC Irvine. Join geriatrics professionals from across CA to connect & collaborate. Coordinated with support from Drs. Todd James (@Geri_IPE) & @susanschneiderucsf.bsky.social! #CAGI2025
Reposted by John Newman, MD, PhD
Our CEO, Eric Verdin answered questions about the administration’s proposed budget cuts to the NIH at a hearing before the Senate Special Committee on Aging this afternoon. Hear his exchange with Angela Alsobrook D-MD here: youtu.be/XrhHldez1AI
Eric Verdin, MD, President of the Buck Institute in hearing of the Senate Special Committee on Aging
YouTube video by Buck Institute for Research on Aging
youtu.be
February 13, 2025 at 2:03 AM
Our CEO, Eric Verdin answered questions about the administration’s proposed budget cuts to the NIH at a hearing before the Senate Special Committee on Aging this afternoon. Hear his exchange with Angela Alsobrook D-MD here: youtu.be/XrhHldez1AI
Just two more days to apply to UCSF MSTAR! Applications due Friday Feb 14. A unique opportunity for medical students to immerse themselves in aging research!
Calling all medical students - aging research needs you! Apply now for UCSF 2025 MSTAR summer research program. Learn from all-star mentors how to solve the most meaningful and complex problems facing society. Apps open now, due Feb 14. #Geriatrics #Aging geriatrics.ucsf.edu/education/me...
MSTAR | Geriatrics
The MSTAR program at UCSF is a summer research practicum in San Francisco, CA, designed to immerse first year medical students in aging research.
geriatrics.ucsf.edu
February 12, 2025 at 11:59 PM
Just two more days to apply to UCSF MSTAR! Applications due Friday Feb 14. A unique opportunity for medical students to immerse themselves in aging research!
Reposted by John Newman, MD, PhD
Calling all medical students - aging research needs you! Apply now for UCSF 2025 MSTAR summer research program. Learn from all-star mentors how to solve the most meaningful and complex problems facing society. Apps open now, due Feb 14. #Geriatrics #Aging geriatrics.ucsf.edu/education/me...
MSTAR | Geriatrics
The MSTAR program at UCSF is a summer research practicum in San Francisco, CA, designed to immerse first year medical students in aging research.
geriatrics.ucsf.edu
January 31, 2025 at 10:14 PM
Calling all medical students - aging research needs you! Apply now for UCSF 2025 MSTAR summer research program. Learn from all-star mentors how to solve the most meaningful and complex problems facing society. Apps open now, due Feb 14. #Geriatrics #Aging geriatrics.ucsf.edu/education/me...
Calling all medical students - aging research needs you! Apply now for UCSF 2025 MSTAR summer research program. Learn from all-star mentors how to solve the most meaningful and complex problems facing society. Apps open now, due Feb 14. #Geriatrics #Aging geriatrics.ucsf.edu/education/me...
MSTAR | Geriatrics
The MSTAR program at UCSF is a summer research practicum in San Francisco, CA, designed to immerse first year medical students in aging research.
geriatrics.ucsf.edu
January 31, 2025 at 10:14 PM
Calling all medical students - aging research needs you! Apply now for UCSF 2025 MSTAR summer research program. Learn from all-star mentors how to solve the most meaningful and complex problems facing society. Apps open now, due Feb 14. #Geriatrics #Aging geriatrics.ucsf.edu/education/me...
Reposted by John Newman, MD, PhD
I strongly support the NIH Diversity Supplement Program. Addressing the severe lack of diversity among biomedical researchers improves the quality of research. It's not a level playing field. This program helps restore equity through mentored training. Rescinding this program is a big mistake
January 26, 2025 at 3:37 AM
I strongly support the NIH Diversity Supplement Program. Addressing the severe lack of diversity among biomedical researchers improves the quality of research. It's not a level playing field. This program helps restore equity through mentored training. Rescinding this program is a big mistake
Reposted by John Newman, MD, PhD
What other departments or divisions are doing faculty sessions on teaching how to get on BlueSky? @ucsfgeriatrics.bsky.social is! Thanks @lwaltermd.bsky.social for setting this up! #geriatrics #gerisky
January 22, 2025 at 11:28 PM
What other departments or divisions are doing faculty sessions on teaching how to get on BlueSky? @ucsfgeriatrics.bsky.social is! Thanks @lwaltermd.bsky.social for setting this up! #geriatrics #gerisky
Reposted by John Newman, MD, PhD
Thrilled to announce up to $52M award from ARPA_H for groundbreaking PATH program: Personalized Analytics for Transforming Health. Along with our strategic partner Phenome Health our aim is to predict and prevent diseases to increase individual #healthspan. www.buckinstitute.org/news/buck-in...
Buck Institute and Phenome Health Awarded up to $52M from ARPA-H
Award Aims to Transform Healthcare with Personalized Analytics
www.buckinstitute.org
December 19, 2024 at 6:10 PM
Thrilled to announce up to $52M award from ARPA_H for groundbreaking PATH program: Personalized Analytics for Transforming Health. Along with our strategic partner Phenome Health our aim is to predict and prevent diseases to increase individual #healthspan. www.buckinstitute.org/news/buck-in...
Reposted by John Newman, MD, PhD
Since I've met many new people on @bsky.app, I wanted to re-share this paper we published earlier this year in @naturecomms.bsky.social! We found OXR1, which regulates #longevity and #brainaging through neuronal endocytic recycling. Read below for a summary 👇
www.nature.com/articles/s41...
#GeroSky
www.nature.com/articles/s41...
#GeroSky
OXR1 maintains the retromer to delay brain aging under dietary restriction - Nature Communications
Dietary restriction promotes healthy brain aging, but the mechanism is unknown. Here, the authors show that OXR1 is upregulated by dietary restriction and confers age-related neuroprotection by m...
www.nature.com
December 3, 2024 at 7:37 PM
Since I've met many new people on @bsky.app, I wanted to re-share this paper we published earlier this year in @naturecomms.bsky.social! We found OXR1, which regulates #longevity and #brainaging through neuronal endocytic recycling. Read below for a summary 👇
www.nature.com/articles/s41...
#GeroSky
www.nature.com/articles/s41...
#GeroSky
Reposted by John Newman, MD, PhD
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.
A Place of Joy.
A Place of Joy.
December 3, 2024 at 2:10 PM
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
Our latest work: a new link between metabolism and proteostasis, relevant to Alzheimer's disease. Out today in Cell Chemical Biology as open access! Stay tuned for more discussion of what we found and what it means... @buckinstitute.bsky.social @cellpress.bsky.social
www.cell.com/cell-chemica...
www.cell.com/cell-chemica...
β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain
Madhavan et al. identify and characterize the selective regulation of protein solubility
by the ketone body β-hydroxybutyrate (βHB) across a range of models. βHB exposure
rescues cell-based and C. ele...
www.cell.com
December 2, 2024 at 10:06 PM
Our latest work: a new link between metabolism and proteostasis, relevant to Alzheimer's disease. Out today in Cell Chemical Biology as open access! Stay tuned for more discussion of what we found and what it means... @buckinstitute.bsky.social @cellpress.bsky.social
www.cell.com/cell-chemica...
www.cell.com/cell-chemica...
Reposted by John Newman, MD, PhD
#Ketone bodies are not just about energy. Study in @cellpress.bsky.social shows metabolites are powerful signaling molecules that help clean up damaged proteins. New biology for aging and neurodegenerative disease @geriscidoc.bsky.social @sidmadhavan.bsky.social www.buckinstitute.org/news/ketone-...
Ketone bodies: more than energy, they are powerful signaling metabolites that clean up damaged proteins
Ketone esters help clear misfolded proteins in mouse models of aging and Alzheimer’s disease Ketone bodies, produced by the body to provide fuel during fasting, have roles in regulating cellular pro...
www.buckinstitute.org
December 2, 2024 at 7:10 PM
#Ketone bodies are not just about energy. Study in @cellpress.bsky.social shows metabolites are powerful signaling molecules that help clean up damaged proteins. New biology for aging and neurodegenerative disease @geriscidoc.bsky.social @sidmadhavan.bsky.social www.buckinstitute.org/news/ketone-...
Reposted by John Newman, MD, PhD
We are all going to Alaska!! #AGE2025 as organized by the indomitable Ben Miller at OMRF @benjaminfmiller.bsky.social @americanaging.bsky.social @am-omrf.bsky.social
We're happy to join all of you here on Bluesky! Be sure to give us a follow and check out our site for new announcements and opportunities in research on aging biology!
www.americanagingassociation.org
www.americanagingassociation.org
Home
www.americanagingassociation.org
November 26, 2024 at 7:11 PM
We are all going to Alaska!! #AGE2025 as organized by the indomitable Ben Miller at OMRF @benjaminfmiller.bsky.social @americanaging.bsky.social @am-omrf.bsky.social
One generous gift from Dr. Jim Johnson started a snowball rolling, out of which grew the Buck Clinical Research Core. From one gift for one small study grew millions in funding for a half dozen or more geroscience clinical studies, and still growing. You can have an enormous impact! Thank you!
During this season of giving, we want to express our thanks to our donors. We’ve created a special video featuring scientists from across the Buck, sharing how your contributions have helped make a big difference in our research. We are incredibly grateful for you!
vimeo.com/1009324677/d...
vimeo.com/1009324677/d...
Thank you Buck Donors!
This is "Thank you Buck Donors!" by The Buck Institute on Vimeo, the home for high quality videos and the people who love them.
vimeo.com
November 25, 2024 at 2:59 PM
One generous gift from Dr. Jim Johnson started a snowball rolling, out of which grew the Buck Clinical Research Core. From one gift for one small study grew millions in funding for a half dozen or more geroscience clinical studies, and still growing. You can have an enormous impact! Thank you!
Reposted by John Newman, MD, PhD
During this season of giving, we want to express our thanks to our donors. We’ve created a special video featuring scientists from across the Buck, sharing how your contributions have helped make a big difference in our research. We are incredibly grateful for you!
vimeo.com/1009324677/d...
vimeo.com/1009324677/d...
Thank you Buck Donors!
This is "Thank you Buck Donors!" by The Buck Institute on Vimeo, the home for high quality videos and the people who love them.
vimeo.com
November 25, 2024 at 2:47 PM
During this season of giving, we want to express our thanks to our donors. We’ve created a special video featuring scientists from across the Buck, sharing how your contributions have helped make a big difference in our research. We are incredibly grateful for you!
vimeo.com/1009324677/d...
vimeo.com/1009324677/d...
It's delirium! Not dementia.
Feel free to widely share the one-page flyer and web page linked below, created by the American Delirium Society. Post the flyer in resident work rooms. Build delirium awareness!
americandeliriumsociety.org/wp-content/u...
americandeliriumsociety.org/delirium-awa...
Feel free to widely share the one-page flyer and web page linked below, created by the American Delirium Society. Post the flyer in resident work rooms. Build delirium awareness!
americandeliriumsociety.org/wp-content/u...
americandeliriumsociety.org/delirium-awa...
November 24, 2024 at 3:30 PM
It's delirium! Not dementia.
Feel free to widely share the one-page flyer and web page linked below, created by the American Delirium Society. Post the flyer in resident work rooms. Build delirium awareness!
americandeliriumsociety.org/wp-content/u...
americandeliriumsociety.org/delirium-awa...
Feel free to widely share the one-page flyer and web page linked below, created by the American Delirium Society. Post the flyer in resident work rooms. Build delirium awareness!
americandeliriumsociety.org/wp-content/u...
americandeliriumsociety.org/delirium-awa...