fair
given my line of work and my perhaps unfortunate love for heterodox science it was hard to say no
definitely frustrating at times, especially considering how acutely self aware he can be
given my line of work and my perhaps unfortunate love for heterodox science it was hard to say no
definitely frustrating at times, especially considering how acutely self aware he can be
December 12, 2025 at 7:29 PM
fair
given my line of work and my perhaps unfortunate love for heterodox science it was hard to say no
definitely frustrating at times, especially considering how acutely self aware he can be
given my line of work and my perhaps unfortunate love for heterodox science it was hard to say no
definitely frustrating at times, especially considering how acutely self aware he can be
he wrote a whole book about his experiences with it! i think i need to write a review because it is genuinely interesting and moving at times, and i can't find any reviews that actually deal with the science in a meaningful way
December 12, 2025 at 7:23 PM
he wrote a whole book about his experiences with it! i think i need to write a review because it is genuinely interesting and moving at times, and i can't find any reviews that actually deal with the science in a meaningful way
i think the whole chronic lyme thing is at least part of the story
December 12, 2025 at 6:38 PM
i think the whole chronic lyme thing is at least part of the story
Reposted
The 1-2 punch of "gangs provide identity and create financial, social *and emotional* support where it is otherwise absent" and "cops are indistinguishable from gangs" does lead to some in-hindsight obvious conclusions about secondary, unspoken motivations cops have for closing ranks when questioned
December 1, 2025 at 5:39 PM
The 1-2 punch of "gangs provide identity and create financial, social *and emotional* support where it is otherwise absent" and "cops are indistinguishable from gangs" does lead to some in-hindsight obvious conclusions about secondary, unspoken motivations cops have for closing ranks when questioned
or wait you aren't completely out of butter I misread
replace the oil with the butter, or at mix it in
replace the oil with the butter, or at mix it in
October 7, 2025 at 1:35 AM
or wait you aren't completely out of butter I misread
replace the oil with the butter, or at mix it in
replace the oil with the butter, or at mix it in
split it down the middle, fry it with a hint of oil till it's browned a bit, then drizzle the maple syrup on it
at that point it doesn't matter if it's blasphemy or not
at that point it doesn't matter if it's blasphemy or not
October 7, 2025 at 1:34 AM
split it down the middle, fry it with a hint of oil till it's browned a bit, then drizzle the maple syrup on it
at that point it doesn't matter if it's blasphemy or not
at that point it doesn't matter if it's blasphemy or not
at some point I'd like to write up a post on it, it's quite a nice story and I think it's an underappreciated aspect of the SARS2 vaccines
October 1, 2025 at 5:57 PM
at some point I'd like to write up a post on it, it's quite a nice story and I think it's an underappreciated aspect of the SARS2 vaccines
you guys briefly talk about the RSV vaccine in here -the RSV story is actually closely related to the SARS2 Spike story, both vaccines used the same protein design trick to stabilize the vaccine
the trick was originally figured out for HIV but it turned out to be quite adaptable
the trick was originally figured out for HIV but it turned out to be quite adaptable
October 1, 2025 at 5:56 PM
you guys briefly talk about the RSV vaccine in here -the RSV story is actually closely related to the SARS2 Spike story, both vaccines used the same protein design trick to stabilize the vaccine
the trick was originally figured out for HIV but it turned out to be quite adaptable
the trick was originally figured out for HIV but it turned out to be quite adaptable
ty i was losing my mind trying to figure out how this is different from heterozygote advantage
September 15, 2025 at 9:36 PM
ty i was losing my mind trying to figure out how this is different from heterozygote advantage
ok that was my first guess as well
guess 2: Dawkins
guess 3: Sagan
guess 2: Dawkins
guess 3: Sagan
August 22, 2025 at 9:25 PM
ok that was my first guess as well
guess 2: Dawkins
guess 3: Sagan
guess 2: Dawkins
guess 3: Sagan
Reposted
like. fundamentally, at deep deep bedrock, rationalism as it currently exists is path-dependent on *not* asking questions about who is paying for what, who is manipulating you, and whose power you are contributing to
August 22, 2025 at 4:59 PM
like. fundamentally, at deep deep bedrock, rationalism as it currently exists is path-dependent on *not* asking questions about who is paying for what, who is manipulating you, and whose power you are contributing to
quinault rainforest, or maybe hoh
August 14, 2025 at 2:04 AM
quinault rainforest, or maybe hoh
brb training ptashnegpt
June 30, 2025 at 12:48 AM
brb training ptashnegpt
Reposted
Mainline Protestantism has a tons and tons of churches that won't chase you out for who you are and they, we, are *dying* by the numbers. So I think the larger problem is not pushing people out, but our ability to draw people in in the first place.
June 23, 2025 at 4:16 PM
Mainline Protestantism has a tons and tons of churches that won't chase you out for who you are and they, we, are *dying* by the numbers. So I think the larger problem is not pushing people out, but our ability to draw people in in the first place.
Reposted
We shouldn't make people feel unwelcome unnecessarily. Christianity is, among other things, a project of universal fraternity*. But we can't operate just on selecting *against* things. We have to believe in something. We might as well start with God.
June 23, 2025 at 4:28 PM
We shouldn't make people feel unwelcome unnecessarily. Christianity is, among other things, a project of universal fraternity*. But we can't operate just on selecting *against* things. We have to believe in something. We might as well start with God.
Reposted
Church is expensive. It takes time, money, and emotional energy. It's not enough for churches to just not abuse people, we need to provide value. Meaningful work, not just a flavor of charity to give to. Meaningful connection, not just "a community". Make Big Asks. Worship the living God.
June 23, 2025 at 4:22 PM
Church is expensive. It takes time, money, and emotional energy. It's not enough for churches to just not abuse people, we need to provide value. Meaningful work, not just a flavor of charity to give to. Meaningful connection, not just "a community". Make Big Asks. Worship the living God.
gibbons also have pretty crazy rate of chromosomal rearrangements/karyotype evo, possibly due to errors in chromosomal segregation
www.nature.com/articles/nature13679
www.sciencedirect.com/science/article/pii/S2666979X25000643
www.nature.com/articles/nature13679
www.sciencedirect.com/science/article/pii/S2666979X25000643
June 18, 2025 at 6:31 PM
gibbons also have pretty crazy rate of chromosomal rearrangements/karyotype evo, possibly due to errors in chromosomal segregation
www.nature.com/articles/nature13679
www.sciencedirect.com/science/article/pii/S2666979X25000643
www.nature.com/articles/nature13679
www.sciencedirect.com/science/article/pii/S2666979X25000643
unclear to me whether it still contains sufficient toxins to hurt a dog, probably best to play it safe
mature common milkweed plants may also be more bitter and more dangerous
mature common milkweed plants may also be more bitter and more dangerous
June 3, 2025 at 2:17 AM
unclear to me whether it still contains sufficient toxins to hurt a dog, probably best to play it safe
mature common milkweed plants may also be more bitter and more dangerous
mature common milkweed plants may also be more bitter and more dangerous
worth noting that according to foraging expert Sam Thayer, Asclepias syriaca, the common milkweed, is not bitter at all, even when eaten raw, at least the young shoots which people eat
www.foragersharvest.com/newsletter/m...
www.foragersharvest.com/newsletter/m...
MilkWeed: A Truely Remarkable Wild Vegetable
Hello Foraging Friends, Summer is progressing nicely here in NW Wisconsin and berry season is right around the corner. Years ago I started a monthly newsletter about foraging. It was a very...
www.foragersharvest.com
June 3, 2025 at 2:16 AM
worth noting that according to foraging expert Sam Thayer, Asclepias syriaca, the common milkweed, is not bitter at all, even when eaten raw, at least the young shoots which people eat
www.foragersharvest.com/newsletter/m...
www.foragersharvest.com/newsletter/m...
hrmmph still can't these things to run on the boltz colab
man i really dont want to have to figure out how to run this on our cluster
man i really dont want to have to figure out how to run this on our cluster
May 29, 2025 at 7:46 PM
hrmmph still can't these things to run on the boltz colab
man i really dont want to have to figure out how to run this on our cluster
man i really dont want to have to figure out how to run this on our cluster
would use AF2 but have never been able to get it work with big glycoprotein complexes
May 29, 2025 at 6:16 PM
would use AF2 but have never been able to get it work with big glycoprotein complexes
modeling some weird viral proteins we're trying to engineer into something useful for gene therapy
May 29, 2025 at 6:14 PM
modeling some weird viral proteins we're trying to engineer into something useful for gene therapy