Genome Biology and Evolution
@genomebiolevol.bsky.social
GBE publishes leading original research at the interface between evolutionary biology and genomics.
🔗 academic.oup.com/gbe
🏠 @official-smbe.bsky.social
🤝 @molbioevol.bsky.social
#genome #evolution #science #biology #societyjournal
🔗 academic.oup.com/gbe
🏠 @official-smbe.bsky.social
🤝 @molbioevol.bsky.social
#genome #evolution #science #biology #societyjournal
Pinned
The November cover of Genome Biology and Evolution features @raularayadonoso.bsky.social @kenrokusumi.bsky.social @anthonygeneva.bsky.social et al., who studied how structural rearrangements and selection promote phenotypic evolution in Anolis.
🔗 doi.org/10.1093/gbe/evaf196
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf196
#genome #evolution
@simaranjohal.bsky.social et al. compared Sox gene orthologs and paralogs in vertebrates, highlighting the molecular basis for functional divergence via subfunctionalization through accelerated sequence divergence.
🔗 doi.org/10.1093/gbe/evaf213
#genome #evolution #evodevo
🔗 doi.org/10.1093/gbe/evaf213
#genome #evolution #evodevo
Molecular and Functional Divergence of Zebrafish Sox Paralogs Controlling Endoderm Formation and Left–Right Patterning
Abstract. Endoderm, one of three primary germ layers of vertebrate embryos, makes major contributions to the respiratory and gastrointestinal tracts and as
doi.org
November 26, 2025 at 4:59 PM
@simaranjohal.bsky.social et al. compared Sox gene orthologs and paralogs in vertebrates, highlighting the molecular basis for functional divergence via subfunctionalization through accelerated sequence divergence.
🔗 doi.org/10.1093/gbe/evaf213
#genome #evolution #evodevo
🔗 doi.org/10.1093/gbe/evaf213
#genome #evolution #evodevo
Joshi et al. used a comparative framework based on the annotation of regulatory sequences to show that these are under an increased natural selection than the genomic background.
🔗 doi.org/10.1093/gbe/evaf212
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf212
#genome #evolution
November 26, 2025 at 4:50 PM
Joshi et al. used a comparative framework based on the annotation of regulatory sequences to show that these are under an increased natural selection than the genomic background.
🔗 doi.org/10.1093/gbe/evaf212
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf212
#genome #evolution
Tabatabaee et al. introduce CASTLES-Pro for estimating species tree branch lengths while accounting for both gene duplication and loss and incomplete lineage sorting.
🔗 doi.org/10.1093/gbe/evaf200
#genome #evolution #phylogenetics
🔗 doi.org/10.1093/gbe/evaf200
#genome #evolution #phylogenetics
Species Tree Branch Length Estimation despite Incomplete Lineage Sorting, Duplication, and Loss
Abstract. Phylogenetic branch lengths are essential for many analyses, such as estimating divergence times, analyzing rate changes, and studying adaptation
doi.org
November 26, 2025 at 4:44 PM
Tabatabaee et al. introduce CASTLES-Pro for estimating species tree branch lengths while accounting for both gene duplication and loss and incomplete lineage sorting.
🔗 doi.org/10.1093/gbe/evaf200
#genome #evolution #phylogenetics
🔗 doi.org/10.1093/gbe/evaf200
#genome #evolution #phylogenetics
@alexgilardet.bsky.social et al. recovered ancient DNA from bovine bones in the Denisova cave to characterize Pleistocene bovine diversity, identifying the Altai Mountains as a hotspot for bovine diversity.
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
Paleogenomics Reveals a Loss of Bovine Lineages in Mid-latitude Asia Over the Last 200,000 Years
Abstract. Bovines have a complex yet poorly understood evolutionary history that is characterized by admixture and diversity loss during the Late Pleistoce
doi.org
November 24, 2025 at 9:31 AM
@alexgilardet.bsky.social et al. recovered ancient DNA from bovine bones in the Denisova cave to characterize Pleistocene bovine diversity, identifying the Altai Mountains as a hotspot for bovine diversity.
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
🔗 doi.org/10.1093/gbe/evaf206
#genome #evolution #aDNA #denisova
R. Yuan & J. Zhang tested whether males had a greater mtDNA mutation load than females - the mother's curse hypothesis - using genotype and phenotype data from the UK Biobank. Their findings do not support the mother's curse hypothesis in humans.
🔗 doi.org/10.1093/gbe/evaf207
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf207
#genome #evolution
Testing the Mother's Curse Hypothesis in Human Mitochondrial Genome Evolution
Abstract. In species where mitochondrial DNA (mtDNA) is maternally inherited such as vertebrates, mtDNA mutations harming males only are not subject to pur
doi.org
November 24, 2025 at 9:22 AM
R. Yuan & J. Zhang tested whether males had a greater mtDNA mutation load than females - the mother's curse hypothesis - using genotype and phenotype data from the UK Biobank. Their findings do not support the mother's curse hypothesis in humans.
🔗 doi.org/10.1093/gbe/evaf207
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf207
#genome #evolution
Reposted by Genome Biology and Evolution
New paper from the lab, where we sequenced the genome of Europe's most venomous snake, Western nose-horned viper (Vipera ammodytes ammodytes)!
Read paper in Genome Biology and Evolution: academic.oup.com/gbe/advance-...
Read paper in Genome Biology and Evolution: academic.oup.com/gbe/advance-...
November 11, 2025 at 2:33 PM
New paper from the lab, where we sequenced the genome of Europe's most venomous snake, Western nose-horned viper (Vipera ammodytes ammodytes)!
Read paper in Genome Biology and Evolution: academic.oup.com/gbe/advance-...
Read paper in Genome Biology and Evolution: academic.oup.com/gbe/advance-...
Reposted by Genome Biology and Evolution
🧬New from @symbionticism.bsky.social's Lab:
The male-killing gene wmk in Wolbachia splits into 5 types with distinct genomic patterns. Variation in copy number and expression helps explain male-biased lethality across hosts.
Read more: academic.oup.com/gbe/article/...
The male-killing gene wmk in Wolbachia splits into 5 types with distinct genomic patterns. Variation in copy number and expression helps explain male-biased lethality across hosts.
Read more: academic.oup.com/gbe/article/...
Evolutionary Diversification and Functions of the Candidate Male Killing Gene wmk
Abstract. Symbiont-mediated male killing (MK) is a mechanism that selectively eliminates male offspring, often by disrupting sex-specific developmental pro
academic.oup.com
November 18, 2025 at 9:47 PM
🧬New from @symbionticism.bsky.social's Lab:
The male-killing gene wmk in Wolbachia splits into 5 types with distinct genomic patterns. Variation in copy number and expression helps explain male-biased lethality across hosts.
Read more: academic.oup.com/gbe/article/...
The male-killing gene wmk in Wolbachia splits into 5 types with distinct genomic patterns. Variation in copy number and expression helps explain male-biased lethality across hosts.
Read more: academic.oup.com/gbe/article/...
Marturano et al. surveyed the presence and biological features of smithRNAs - a novel class of small noncoding RNAs - across Metazoa, identifying their presence in all species studied, including vertebrates, cnidarians, and arthropods.
🔗 doi.org/10.1093/gbe/evaf208
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf208
#genome #evolution
November 21, 2025 at 12:34 PM
Marturano et al. surveyed the presence and biological features of smithRNAs - a novel class of small noncoding RNAs - across Metazoa, identifying their presence in all species studied, including vertebrates, cnidarians, and arthropods.
🔗 doi.org/10.1093/gbe/evaf208
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf208
#genome #evolution
@tywooldr.bsky.social et al. present assemblies for three bear species — the sun, sloth, and Andean bears — and use a whole-genome alignment of all bear species and other carnivores to reconstruct the evolution of Ursidae.
🔗 doi.org/10.1093/gbe/evaf188
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf188
#genome #evolution
Chromosome-scale Genomes Show Rapid Diversification and Ancient Gene Flow Among Bear Species
Abstract. Reconstructions of evolutionary history can be restricted by a lack of high-quality reference genomes. To date, only four of the eight species of
doi.org
November 20, 2025 at 4:46 PM
@tywooldr.bsky.social et al. present assemblies for three bear species — the sun, sloth, and Andean bears — and use a whole-genome alignment of all bear species and other carnivores to reconstruct the evolution of Ursidae.
🔗 doi.org/10.1093/gbe/evaf188
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf188
#genome #evolution
Reposted by Genome Biology and Evolution
Our manuscript on bovine deep-time paleogenomics at Denisova Cave and in the broader mid-latitude Asia is online! doi.org/10.1093/gbe/... 🦬🦴🧬
Main findings in the 🧵 below ⬇️
@cpgsthlm.bsky.social @genomebiolevol.bsky.social #aDNA
Main findings in the 🧵 below ⬇️
@cpgsthlm.bsky.social @genomebiolevol.bsky.social #aDNA
Paleogenomics Reveals a Loss of Bovine Lineages in Mid-latitude Asia Over the Last 200,000 Years
Abstract. Bovines have a complex yet poorly understood evolutionary history that is characterized by admixture and diversity loss during the Late Pleistoce
doi.org
November 20, 2025 at 9:52 AM
Our manuscript on bovine deep-time paleogenomics at Denisova Cave and in the broader mid-latitude Asia is online! doi.org/10.1093/gbe/... 🦬🦴🧬
Main findings in the 🧵 below ⬇️
@cpgsthlm.bsky.social @genomebiolevol.bsky.social #aDNA
Main findings in the 🧵 below ⬇️
@cpgsthlm.bsky.social @genomebiolevol.bsky.social #aDNA
Pegan & Winger tested whether inversions are common within populations without phenotypic polymorphisms in 28 N. American bird species, finding that many polymorphisms are present at balanced frequencies, but possibly segregating neutrally.
🔗 doi.org/10.1093/gbe/evaf205
#genome #evolution #birds
🔗 doi.org/10.1093/gbe/evaf205
#genome #evolution #birds
November 20, 2025 at 12:05 PM
Pegan & Winger tested whether inversions are common within populations without phenotypic polymorphisms in 28 N. American bird species, finding that many polymorphisms are present at balanced frequencies, but possibly segregating neutrally.
🔗 doi.org/10.1093/gbe/evaf205
#genome #evolution #birds
🔗 doi.org/10.1093/gbe/evaf205
#genome #evolution #birds
Grandchamp, @drdomain.bsky.social et al. publish a new Review on commonly used methods for de novo gene detection, address the limitations of nomenclature and detection methods, and establish a de novo gene annotation format to standardize reporting
🔗 doi.org/10.1093/gbe/evaf197
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf197
#genome #evolution
November 19, 2025 at 11:48 AM
Grandchamp, @drdomain.bsky.social et al. publish a new Review on commonly used methods for de novo gene detection, address the limitations of nomenclature and detection methods, and establish a de novo gene annotation format to standardize reporting
🔗 doi.org/10.1093/gbe/evaf197
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf197
#genome #evolution
Reposted by Genome Biology and Evolution
New genome assembly of a land snail🐌🎉
Krishnan et al. present annotated nuclear and mitochondrial genome assemblies of Indrella ampulla, a color polymorphic land snail endemic to the Western Ghats of India. The assembly has N50 of 632 kb, and 93.5% BUSCO completeness.
🔗 doi.org/10.1093/gbe/evaf199
#genome #evolution #snail
🔗 doi.org/10.1093/gbe/evaf199
#genome #evolution #snail
November 19, 2025 at 2:50 AM
New genome assembly of a land snail🐌🎉
Krishnan et al. present annotated nuclear and mitochondrial genome assemblies of Indrella ampulla, a color polymorphic land snail endemic to the Western Ghats of India. The assembly has N50 of 632 kb, and 93.5% BUSCO completeness.
🔗 doi.org/10.1093/gbe/evaf199
#genome #evolution #snail
🔗 doi.org/10.1093/gbe/evaf199
#genome #evolution #snail
November 18, 2025 at 11:12 AM
Krishnan et al. present annotated nuclear and mitochondrial genome assemblies of Indrella ampulla, a color polymorphic land snail endemic to the Western Ghats of India. The assembly has N50 of 632 kb, and 93.5% BUSCO completeness.
🔗 doi.org/10.1093/gbe/evaf199
#genome #evolution #snail
🔗 doi.org/10.1093/gbe/evaf199
#genome #evolution #snail
@jolijnerven.bsky.social @gingerhowley.bsky.social et al. used genotype imputation on published goat palaeogenomes to study their domestication; their findings challenge long-standing assumptions about domestication bottlenecks.
🔗 doi.org/10.1093/gbe/evaf181
#genome #evolution #domestication
🔗 doi.org/10.1093/gbe/evaf181
#genome #evolution #domestication
November 18, 2025 at 11:04 AM
@jolijnerven.bsky.social @gingerhowley.bsky.social et al. used genotype imputation on published goat palaeogenomes to study their domestication; their findings challenge long-standing assumptions about domestication bottlenecks.
🔗 doi.org/10.1093/gbe/evaf181
#genome #evolution #domestication
🔗 doi.org/10.1093/gbe/evaf181
#genome #evolution #domestication
Reposted by Genome Biology and Evolution
Check out our paper, we now included a comparison between glimse1 and glimpse2!
Our paper on imputation of ancient goat genomes is now available at GBE - congratulations to @jolijnerven.bsky.social #aDNA
Inferring Domestic Goat Demographic History Through Ancient Genome Imputation
Abstract. Goats were among the earliest managed animals, making them a natural model to explore the genetic consequences of domestication. However, a chall
academic.oup.com
November 11, 2025 at 9:01 AM
Check out our paper, we now included a comparison between glimse1 and glimpse2!
Reposted by Genome Biology and Evolution
Our paper on imputation of ancient goat genomes is now available at GBE - congratulations to @jolijnerven.bsky.social #aDNA
Inferring Domestic Goat Demographic History Through Ancient Genome Imputation
Abstract. Goats were among the earliest managed animals, making them a natural model to explore the genetic consequences of domestication. However, a chall
academic.oup.com
November 10, 2025 at 6:49 PM
Our paper on imputation of ancient goat genomes is now available at GBE - congratulations to @jolijnerven.bsky.social #aDNA
@katharinasures.bsky.social @probstlab.bsky.social et al. analysed CRISPR-Cas systems of metagenome-assembled genomes from two subsurface environments, shedding new light on the diversity of CRISPR spacers in natural microbial communities.
🔗 doi.org/10.1093/gbe/evaf201
#genome #evolution #CRISPR
🔗 doi.org/10.1093/gbe/evaf201
#genome #evolution #CRISPR
Acquisition of Spacers from Foreign Prokaryotic Genomes by CRISPR-Cas Systems in Natural Environments
Abstract. Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems of bacteria and archaea provide immunities
doi.org
November 18, 2025 at 10:53 AM
@katharinasures.bsky.social @probstlab.bsky.social et al. analysed CRISPR-Cas systems of metagenome-assembled genomes from two subsurface environments, shedding new light on the diversity of CRISPR spacers in natural microbial communities.
🔗 doi.org/10.1093/gbe/evaf201
#genome #evolution #CRISPR
🔗 doi.org/10.1093/gbe/evaf201
#genome #evolution #CRISPR
Reposted by Genome Biology and Evolution
Very proud to share our perspective on "The Genomic Kaleidoscope" doi.org/10.1093/gbe/... out @genomebiolevol.bsky.social
Precious collaboration w/ colleagues across the world, led alongside the amazing @mbrasovives.bsky.social and the one&only @jrotwitguez.bsky.social
Check out his great thread!
Precious collaboration w/ colleagues across the world, led alongside the amazing @mbrasovives.bsky.social and the one&only @jrotwitguez.bsky.social
Check out his great thread!
November 17, 2025 at 2:29 PM
Very proud to share our perspective on "The Genomic Kaleidoscope" doi.org/10.1093/gbe/... out @genomebiolevol.bsky.social
Precious collaboration w/ colleagues across the world, led alongside the amazing @mbrasovives.bsky.social and the one&only @jrotwitguez.bsky.social
Check out his great thread!
Precious collaboration w/ colleagues across the world, led alongside the amazing @mbrasovives.bsky.social and the one&only @jrotwitguez.bsky.social
Check out his great thread!
Reposted by Genome Biology and Evolution
We are excited to share @probstlab.bsky.social's latest publication on the diversity of CRISPR-Cas spacers, led by @katharinasures.bsky.social !! 🧬
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Acquisition of Spacers from Foreign Prokaryotic Genomes by CRISPR-Cas Systems in Natural Environments
Abstract. Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems of bacteria and archaea provide immunities
doi.org
November 17, 2025 at 12:09 PM
We are excited to share @probstlab.bsky.social's latest publication on the diversity of CRISPR-Cas spacers, led by @katharinasures.bsky.social !! 🧬
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Have a read!! ➡️ doi.org/10.1093/gbe/...
@emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!
Reposted by Genome Biology and Evolution
🚨 New Paper Alert!
Our latest perspective piece is out, and it’s one you won’t want to miss- 'The Genomic Kaleidoscope'
academic.oup.com/gbe/article/...
Co-lead by @mbrasovives.bsky.social @jrotwitguez.bsky.social & @diegoharta.bsky.social
📌 Check the full post here👇
Our latest perspective piece is out, and it’s one you won’t want to miss- 'The Genomic Kaleidoscope'
academic.oup.com/gbe/article/...
Co-lead by @mbrasovives.bsky.social @jrotwitguez.bsky.social & @diegoharta.bsky.social
📌 Check the full post here👇
November 14, 2025 at 4:25 PM
🚨 New Paper Alert!
Our latest perspective piece is out, and it’s one you won’t want to miss- 'The Genomic Kaleidoscope'
academic.oup.com/gbe/article/...
Co-lead by @mbrasovives.bsky.social @jrotwitguez.bsky.social & @diegoharta.bsky.social
📌 Check the full post here👇
Our latest perspective piece is out, and it’s one you won’t want to miss- 'The Genomic Kaleidoscope'
academic.oup.com/gbe/article/...
Co-lead by @mbrasovives.bsky.social @jrotwitguez.bsky.social & @diegoharta.bsky.social
📌 Check the full post here👇
Reposted by Genome Biology and Evolution
First publication during my PhD is now accepted! Thanks SMBE24 'Hidden Dimensions' team for making it happen.
Brasó-Vives et al. publish a new Perspective in GBE, highlighting underexplored dimensions of genomic variation that contribute to phenotypic diversity beyond the DNA sequence, contributing to our understanding of genome evolution.
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
November 14, 2025 at 2:52 PM
First publication during my PhD is now accepted! Thanks SMBE24 'Hidden Dimensions' team for making it happen.
Reposted by Genome Biology and Evolution
Great to see this exciting perspective by young evolutionary biologists lead by the amazing @mbrasovives.bsky.social out!
Brasó-Vives et al. publish a new Perspective in GBE, highlighting underexplored dimensions of genomic variation that contribute to phenotypic diversity beyond the DNA sequence, contributing to our understanding of genome evolution.
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
November 14, 2025 at 12:21 PM
Great to see this exciting perspective by young evolutionary biologists lead by the amazing @mbrasovives.bsky.social out!
Brasó-Vives et al. publish a new Perspective in GBE, highlighting underexplored dimensions of genomic variation that contribute to phenotypic diversity beyond the DNA sequence, contributing to our understanding of genome evolution.
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
November 14, 2025 at 12:17 PM
Brasó-Vives et al. publish a new Perspective in GBE, highlighting underexplored dimensions of genomic variation that contribute to phenotypic diversity beyond the DNA sequence, contributing to our understanding of genome evolution.
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf204
#genome #evolution
Reposted by Genome Biology and Evolution
Are you looking for a brief and clear perspective on the factors associated with between-individual variation that go beyond SNPs? Check out the thread below 👇 It was a pleasure to particpate in this, and shout-out to James @jphippstan.bsky.social who led our contribution to this perspective🧬
🔊New perspective piece out @genomebiolevol.bsky.social.
"The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity" 💡🌀🌈
doi.org/10.1093/gbe/...
Co-led with @mbrasovives.bsky.social and @diegoharta.bsky.social
Check out our thread! 🧵👇 (1/n)
"The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity" 💡🌀🌈
doi.org/10.1093/gbe/...
Co-led with @mbrasovives.bsky.social and @diegoharta.bsky.social
Check out our thread! 🧵👇 (1/n)
Validate User
doi.org
November 14, 2025 at 10:51 AM
Are you looking for a brief and clear perspective on the factors associated with between-individual variation that go beyond SNPs? Check out the thread below 👇 It was a pleasure to particpate in this, and shout-out to James @jphippstan.bsky.social who led our contribution to this perspective🧬