Prof G
@gavingiovannoni.bsky.social
Gavin Giovannoni is a neurologist in the Faculty of Medicine at Queen Mary University of London. His current research is focused on the Epstein-Barr virus as a possible cause of multiple sclerosis. Gavin is an active MS blogger.
What a journey for people with MS and their HCPs. Natalizumab has taught us a great deal about MS. We try to tell the story in this review paper => buff.ly/WWjC7Ql
September 18, 2025 at 4:49 AM
What a journey for people with MS and their HCPs. Natalizumab has taught us a great deal about MS. We try to tell the story in this review paper => buff.ly/WWjC7Ql
#MS_Selfie - Recurring UTIs - some non-antibiotic solutions
How many of you have been taught how to self-manage your bladder to prevent UTIs?
buff.ly/5WwcoJB
How many of you have been taught how to self-manage your bladder to prevent UTIs?
buff.ly/5WwcoJB
August 22, 2025 at 10:44 AM
#MS_Selfie - Recurring UTIs - some non-antibiotic solutions
How many of you have been taught how to self-manage your bladder to prevent UTIs?
buff.ly/5WwcoJB
How many of you have been taught how to self-manage your bladder to prevent UTIs?
buff.ly/5WwcoJB
In this systematic review on the prediction of long-term outcome in Multiple Sclerosis, we try to identify factors that can be included in a prognostic calculator. Please note this calculator needs to be coded and then validated #MS_Selfie => buff.ly/ZhWyK86
August 15, 2025 at 3:17 PM
In this systematic review on the prediction of long-term outcome in Multiple Sclerosis, we try to identify factors that can be included in a prognostic calculator. Please note this calculator needs to be coded and then validated #MS_Selfie => buff.ly/ZhWyK86
#MS_Selfie Q&A 101: worsening visual blurring
If someone experiences visual changes due to MS, does it always show up on optic nerve scans and eye exams? To find out => gavingiovannoni.substack.com/p/q-and-a-10...
If someone experiences visual changes due to MS, does it always show up on optic nerve scans and eye exams? To find out => gavingiovannoni.substack.com/p/q-and-a-10...
July 28, 2025 at 3:24 PM
#MS_Selfie Q&A 101: worsening visual blurring
If someone experiences visual changes due to MS, does it always show up on optic nerve scans and eye exams? To find out => gavingiovannoni.substack.com/p/q-and-a-10...
If someone experiences visual changes due to MS, does it always show up on optic nerve scans and eye exams? To find out => gavingiovannoni.substack.com/p/q-and-a-10...
#BrainHealth – #TimeMatters: Multiple Sclerosis, NMOSD, MOGAD, and Related Conditions. 2024 report
Changing the management and outcome of MS and related disorders, one policy at a time. Please download, read, copy, distribute, and act now.
buff.ly/LNAFNp0
Changing the management and outcome of MS and related disorders, one policy at a time. Please download, read, copy, distribute, and act now.
buff.ly/LNAFNp0
June 27, 2025 at 11:33 AM
#BrainHealth – #TimeMatters: Multiple Sclerosis, NMOSD, MOGAD, and Related Conditions. 2024 report
Changing the management and outcome of MS and related disorders, one policy at a time. Please download, read, copy, distribute, and act now.
buff.ly/LNAFNp0
Changing the management and outcome of MS and related disorders, one policy at a time. Please download, read, copy, distribute, and act now.
buff.ly/LNAFNp0
#MS_Selfie Q&A 97: Chemobrain?
The chemotherapy you had for your ovarian cancer (cisplatin and taxol) are neurotoxic and are likely to have contributed to your worsening MS function or SAW. buff.ly/SfhLCpW
The chemotherapy you had for your ovarian cancer (cisplatin and taxol) are neurotoxic and are likely to have contributed to your worsening MS function or SAW. buff.ly/SfhLCpW
June 24, 2025 at 7:41 AM
#MS_Selfie Q&A 97: Chemobrain?
The chemotherapy you had for your ovarian cancer (cisplatin and taxol) are neurotoxic and are likely to have contributed to your worsening MS function or SAW. buff.ly/SfhLCpW
The chemotherapy you had for your ovarian cancer (cisplatin and taxol) are neurotoxic and are likely to have contributed to your worsening MS function or SAW. buff.ly/SfhLCpW
#MS_Selfie Newsletter and Podcast Q&A 92: shingles on ocrelizumab
Is shingles a common complication of ocrelizumab treatment? => gavingiovannoni.substack.com/p/q-and-a-92...
Is shingles a common complication of ocrelizumab treatment? => gavingiovannoni.substack.com/p/q-and-a-92...
May 23, 2025 at 9:50 AM
#MS_Selfie Newsletter and Podcast Q&A 92: shingles on ocrelizumab
Is shingles a common complication of ocrelizumab treatment? => gavingiovannoni.substack.com/p/q-and-a-92...
Is shingles a common complication of ocrelizumab treatment? => gavingiovannoni.substack.com/p/q-and-a-92...
#MS_Selfie Q&A 89: Nocturnal spasms
How have you sorted out early morning spasms, most likely due to the wearing off of baclofen and gabapentin? buff.ly/79RLOcz
How have you sorted out early morning spasms, most likely due to the wearing off of baclofen and gabapentin? buff.ly/79RLOcz
May 5, 2025 at 4:35 AM
#MS_Selfie Q&A 89: Nocturnal spasms
How have you sorted out early morning spasms, most likely due to the wearing off of baclofen and gabapentin? buff.ly/79RLOcz
How have you sorted out early morning spasms, most likely due to the wearing off of baclofen and gabapentin? buff.ly/79RLOcz
#MS_Selfie Q&A 88: Estriol vs. Estradiol as an HRT for brain health
Estradiol is the most potent endogenous estrogen, extensively studied, and the primary estrogen component in numerous approved HRT formulations used for managing menopausal symptoms..... buff.ly/7BRY2Gf
Estradiol is the most potent endogenous estrogen, extensively studied, and the primary estrogen component in numerous approved HRT formulations used for managing menopausal symptoms..... buff.ly/7BRY2Gf
April 30, 2025 at 7:30 AM
#MS_Selfie Q&A 88: Estriol vs. Estradiol as an HRT for brain health
Estradiol is the most potent endogenous estrogen, extensively studied, and the primary estrogen component in numerous approved HRT formulations used for managing menopausal symptoms..... buff.ly/7BRY2Gf
Estradiol is the most potent endogenous estrogen, extensively studied, and the primary estrogen component in numerous approved HRT formulations used for managing menopausal symptoms..... buff.ly/7BRY2Gf
#MS_Selfie Q&A 87: worsening hand function in MS
The following explains how MS affects hand function, the spectrum of MS-related symptoms, the complexities of assessing hand function, and the requirements for hand rehabilitation. => buff.ly/cnvZtvd
The following explains how MS affects hand function, the spectrum of MS-related symptoms, the complexities of assessing hand function, and the requirements for hand rehabilitation. => buff.ly/cnvZtvd
April 28, 2025 at 9:37 AM
#MS_Selfie Q&A 87: worsening hand function in MS
The following explains how MS affects hand function, the spectrum of MS-related symptoms, the complexities of assessing hand function, and the requirements for hand rehabilitation. => buff.ly/cnvZtvd
The following explains how MS affects hand function, the spectrum of MS-related symptoms, the complexities of assessing hand function, and the requirements for hand rehabilitation. => buff.ly/cnvZtvd
#MS_Selfie Q&A 86: STRATIFY-JCV (Tysabri) versus ImmunoWell (Tyruko)
At the moment, I would sit tight and wait for tolebrutinib. Another option is to be labelled as having SPMS and starting siponimod. => buff.ly/MZxbQcG
At the moment, I would sit tight and wait for tolebrutinib. Another option is to be labelled as having SPMS and starting siponimod. => buff.ly/MZxbQcG
April 17, 2025 at 1:57 PM
#MS_Selfie Q&A 86: STRATIFY-JCV (Tysabri) versus ImmunoWell (Tyruko)
At the moment, I would sit tight and wait for tolebrutinib. Another option is to be labelled as having SPMS and starting siponimod. => buff.ly/MZxbQcG
At the moment, I would sit tight and wait for tolebrutinib. Another option is to be labelled as having SPMS and starting siponimod. => buff.ly/MZxbQcG
Q&A 85: RIS or RRMS? What about PPMS?
Please tell her that both tolebrutinib and fenebrutinib, two new-generation BTK inhibitors, are in trials to treat primary progressive MS. buff.ly/NsuRLbx
Please tell her that both tolebrutinib and fenebrutinib, two new-generation BTK inhibitors, are in trials to treat primary progressive MS. buff.ly/NsuRLbx
April 14, 2025 at 5:57 AM
Q&A 85: RIS or RRMS? What about PPMS?
Please tell her that both tolebrutinib and fenebrutinib, two new-generation BTK inhibitors, are in trials to treat primary progressive MS. buff.ly/NsuRLbx
Please tell her that both tolebrutinib and fenebrutinib, two new-generation BTK inhibitors, are in trials to treat primary progressive MS. buff.ly/NsuRLbx
Finally, I have published an article on "MS-Selfie: a self-management portal to help people with multiple sclerosis" in the British Journal of Neuroscience Nursing. Please read it if you have access. Thanks => buff.ly/iahYY5p
April 4, 2025 at 8:40 AM
Finally, I have published an article on "MS-Selfie: a self-management portal to help people with multiple sclerosis" in the British Journal of Neuroscience Nursing. Please read it if you have access. Thanks => buff.ly/iahYY5p
Slowly but surely, we continue to populate the MS-Selfie microsite with material to help people with MS self-manage MS or to at least ask the right questions. Please check out this section on sleep disorders in MS => buff.ly/CDdXs20
March 28, 2025 at 5:46 AM
Slowly but surely, we continue to populate the MS-Selfie microsite with material to help people with MS self-manage MS or to at least ask the right questions. Please check out this section on sleep disorders in MS => buff.ly/CDdXs20
If you want to know more about smouldering MS, please watch and listen to this online content. It is becoming a very sticky term => buff.ly/U4wwvOA
March 27, 2025 at 4:42 AM
If you want to know more about smouldering MS, please watch and listen to this online content. It is becoming a very sticky term => buff.ly/U4wwvOA
#MS_Selfie Q&A 81: Low JCV-index positive: should I switch to an anti-CD20 therapy or not?
Have any of you pwMS on natalizumab have similar concerns? How many of you have a low JCV index positive and have decided to stay on natalizumab? buff.ly/A3RS1Q0
Have any of you pwMS on natalizumab have similar concerns? How many of you have a low JCV index positive and have decided to stay on natalizumab? buff.ly/A3RS1Q0
March 19, 2025 at 8:41 AM
#MS_Selfie Q&A 81: Low JCV-index positive: should I switch to an anti-CD20 therapy or not?
Have any of you pwMS on natalizumab have similar concerns? How many of you have a low JCV index positive and have decided to stay on natalizumab? buff.ly/A3RS1Q0
Have any of you pwMS on natalizumab have similar concerns? How many of you have a low JCV index positive and have decided to stay on natalizumab? buff.ly/A3RS1Q0
#MS_Selfie Podcast & Newsletter
Do you know how to measure your blood pressure? Do you have a vascular comorbidity? If you are not sure, you need to find out. => buff.ly/KZFjH3O
Do you know how to measure your blood pressure? Do you have a vascular comorbidity? If you are not sure, you need to find out. => buff.ly/KZFjH3O
March 17, 2025 at 10:37 AM
#MS_Selfie Podcast & Newsletter
Do you know how to measure your blood pressure? Do you have a vascular comorbidity? If you are not sure, you need to find out. => buff.ly/KZFjH3O
Do you know how to measure your blood pressure? Do you have a vascular comorbidity? If you are not sure, you need to find out. => buff.ly/KZFjH3O
Please read this Medscape article, "Neurologist Mental Health & Well-Being Report 2025". Now I understand why my colleagues are so burnt out and depressed with their lot. Is it not time we did something about this? => buff.ly/t1hCtAh
March 13, 2025 at 6:08 AM
Please read this Medscape article, "Neurologist Mental Health & Well-Being Report 2025". Now I understand why my colleagues are so burnt out and depressed with their lot. Is it not time we did something about this? => buff.ly/t1hCtAh
The data presented in this analysis seriously challenges our concept of what is active MS and how to monitor it. Is it not time to define new descriptors of MS disease activity? Dare I suggest we use RAW, SAW, NEIDA and NESDA? buff.ly/xM9AuzO
March 10, 2025 at 7:20 AM
The data presented in this analysis seriously challenges our concept of what is active MS and how to monitor it. Is it not time to define new descriptors of MS disease activity? Dare I suggest we use RAW, SAW, NEIDA and NESDA? buff.ly/xM9AuzO
Clinical opinions and case studies on understanding and managing hypogammaglobulinaemia in multiple sclerosis: United Kingdom perspective buff.ly/60cADGW
March 9, 2025 at 7:48 AM
Clinical opinions and case studies on understanding and managing hypogammaglobulinaemia in multiple sclerosis: United Kingdom perspective buff.ly/60cADGW
How important will the T-cell response to EBV be in proving that EBV is the cause of MS? The problem with T-cells is that they are too accommodating and promiscuous to be trusted. We need some hard virological evidence or a treatment response. Do you agree? => buff.ly/wtQONQV
March 6, 2025 at 6:31 PM
How important will the T-cell response to EBV be in proving that EBV is the cause of MS? The problem with T-cells is that they are too accommodating and promiscuous to be trusted. We need some hard virological evidence or a treatment response. Do you agree? => buff.ly/wtQONQV
#MS_Selfie Q&A 78: ocrelizumab or anti-CD20 therapies and measles
Should I be concerned about living close to the measles outbreak? Are there any precautions I should be taking? If I get measles, are there any treatments? => buff.ly/jph3Qcz
Should I be concerned about living close to the measles outbreak? Are there any precautions I should be taking? If I get measles, are there any treatments? => buff.ly/jph3Qcz
March 1, 2025 at 9:01 PM
#MS_Selfie Q&A 78: ocrelizumab or anti-CD20 therapies and measles
Should I be concerned about living close to the measles outbreak? Are there any precautions I should be taking? If I get measles, are there any treatments? => buff.ly/jph3Qcz
Should I be concerned about living close to the measles outbreak? Are there any precautions I should be taking? If I get measles, are there any treatments? => buff.ly/jph3Qcz
Will history judge this editorial commentary on "Infectious mononucleosis being a more realistic target for preventing multiple sclerosis" as prescient? I sincerely hope so. What do you think? #PreventMS #EBVvaccine2preventMS => buff.ly/hPDTbLM
March 1, 2025 at 12:48 PM
Will history judge this editorial commentary on "Infectious mononucleosis being a more realistic target for preventing multiple sclerosis" as prescient? I sincerely hope so. What do you think? #PreventMS #EBVvaccine2preventMS => buff.ly/hPDTbLM
#MS_Selfie podcast and newsletter Q&A 75: Natalizumab to tolebrutinib switch
If you have smouldering MS, would you want to switch to tolebrutinib? If you were on natalizumab with evidence of smouldering MS, would you volunteer for the N2T switch and combination study? => https://buff.ly/3CW6k8h
If you have smouldering MS, would you want to switch to tolebrutinib? If you were on natalizumab with evidence of smouldering MS, would you volunteer for the N2T switch and combination study? => https://buff.ly/3CW6k8h
February 19, 2025 at 10:29 AM
#MS_Selfie podcast and newsletter Q&A 75: Natalizumab to tolebrutinib switch
If you have smouldering MS, would you want to switch to tolebrutinib? If you were on natalizumab with evidence of smouldering MS, would you volunteer for the N2T switch and combination study? => https://buff.ly/3CW6k8h
If you have smouldering MS, would you want to switch to tolebrutinib? If you were on natalizumab with evidence of smouldering MS, would you volunteer for the N2T switch and combination study? => https://buff.ly/3CW6k8h
Will this article be seen in the future as a blueprint for how to go about preventing multiple sclerosis?
Infectious mononucleosis is a more realistic target for preventing multiple sclerosis => https://buff.ly/4gLKiTD
Infectious mononucleosis is a more realistic target for preventing multiple sclerosis => https://buff.ly/4gLKiTD
February 18, 2025 at 8:18 AM
Will this article be seen in the future as a blueprint for how to go about preventing multiple sclerosis?
Infectious mononucleosis is a more realistic target for preventing multiple sclerosis => https://buff.ly/4gLKiTD
Infectious mononucleosis is a more realistic target for preventing multiple sclerosis => https://buff.ly/4gLKiTD