Nick Trott
@gastro-rd.bsky.social
🏥 Gastro Dietitian
🎧 Part-time Wedding #DJ
🌾 #CoeliacDisease & #DGBI
Feed: #dietitansky
🎧 Part-time Wedding #DJ
🌾 #CoeliacDisease & #DGBI
Feed: #dietitansky
New validated tool.🎯 The 'FFQ-FODMAP-BE' questionnaire to assess high-FODMAP food intake in adults. Can identify moderate/high FODMAP consumers (80% sensitivity).
(🇧🇪Study). #FODMAP #IBS
📃https://link.springer.com/article/10.1007/s10620-025-09460-7
(🇧🇪Study). #FODMAP #IBS
📃https://link.springer.com/article/10.1007/s10620-025-09460-7
Development and Validation of a Self-Administered Simplified Food Frequency Questionnaire for FODMAP Intake Evaluation (FFQ-FODMAP-BE) - Digestive Diseases and Sciences
Purpose A practical tool to estimate the frequency of high-Fermentable Oligo-Di-Mono-saccharides and Polyols (FODMAP) food intake in Europe is lacking. The aim of this study is to develop and validate...
link.springer.com
October 17, 2025 at 10:30 AM
Reposted by Nick Trott
👉 Don't miss the ESsCD webinar on Refractory Celiac Disease and T-cell Lymphoma!
This Wednesday 15th of October 15:00-16:00 CET.
(Zoom Platform).
us06web.zoom.us/meeting/regi...
This Wednesday 15th of October 15:00-16:00 CET.
(Zoom Platform).
us06web.zoom.us/meeting/regi...
October 14, 2025 at 4:56 PM
👉 Don't miss the ESsCD webinar on Refractory Celiac Disease and T-cell Lymphoma!
This Wednesday 15th of October 15:00-16:00 CET.
(Zoom Platform).
us06web.zoom.us/meeting/regi...
This Wednesday 15th of October 15:00-16:00 CET.
(Zoom Platform).
us06web.zoom.us/meeting/regi...
Position statement of the Microbiota International Clinical Society.
Microbiota testing shows some promise, but needs more rigour, better reporting standards & clinician education to deliver real clinical value.
www.frontiersin.org/journals/mic...
Microbiota testing shows some promise, but needs more rigour, better reporting standards & clinician education to deliver real clinical value.
www.frontiersin.org/journals/mic...
Frontiers | Position statement of the Microbiota International Clinical Society
PREAMBLE The intestinal microbiota is an extraordinarily complex ecosystem composed of trillions of microorganisms, including bacteria, viruses, fungi, and p...
www.frontiersin.org
September 10, 2025 at 6:46 PM
Position statement of the Microbiota International Clinical Society.
Microbiota testing shows some promise, but needs more rigour, better reporting standards & clinician education to deliver real clinical value.
www.frontiersin.org/journals/mic...
Microbiota testing shows some promise, but needs more rigour, better reporting standards & clinician education to deliver real clinical value.
www.frontiersin.org/journals/mic...
Excellent new review on predicting response to the low FODMAP diet. Symptom severity, breath tests + microbiota all explored - but clinical & psychological factors are the most practical right now. Next step: simple validated tools to personalise treatment.
pubmed.ncbi.nlm.nih.gov/40419398/
pubmed.ncbi.nlm.nih.gov/40419398/
August 29, 2025 at 5:58 PM
Excellent new review on predicting response to the low FODMAP diet. Symptom severity, breath tests + microbiota all explored - but clinical & psychological factors are the most practical right now. Next step: simple validated tools to personalise treatment.
pubmed.ncbi.nlm.nih.gov/40419398/
pubmed.ncbi.nlm.nih.gov/40419398/
Coeliac disease is increasing worldwide, shaped by HLA genetics and uncertain environmental factors. Most remain undiagnosed beneath the “Coeliac Iceberg". This paper highlights the need for proactive population screening over case-finding.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
August 29, 2025 at 5:53 PM
Coeliac disease is increasing worldwide, shaped by HLA genetics and uncertain environmental factors. Most remain undiagnosed beneath the “Coeliac Iceberg". This paper highlights the need for proactive population screening over case-finding.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Coeliac disease isn’t just GI symptoms!
😴 Fatigue
🩸 Iron-deficiency anaemia
🦴 Osteoporosis
🧪 Raised LFTs
⚡️ Neuropathy
🤕 Dermatitis herpetiformis
🧠 Brain fog
🤍 Infertility
Often missed for years ⏳
High suspicion = earlier dx = better outcomes ✅
bit.ly/45Wb4a5
😴 Fatigue
🩸 Iron-deficiency anaemia
🦴 Osteoporosis
🧪 Raised LFTs
⚡️ Neuropathy
🤕 Dermatitis herpetiformis
🧠 Brain fog
🤍 Infertility
Often missed for years ⏳
High suspicion = earlier dx = better outcomes ✅
bit.ly/45Wb4a5
Clinical Presentation of the Celiac Disease Patients
Celiac disease (CeD) presents with a wide array of symptoms, affecting nearly every
organ system. This review describes CeD clinical presentation at diagnosis, covering
both gastrointestinal and extra...
bit.ly
July 9, 2025 at 8:07 PM
Coeliac disease isn’t just GI symptoms!
😴 Fatigue
🩸 Iron-deficiency anaemia
🦴 Osteoporosis
🧪 Raised LFTs
⚡️ Neuropathy
🤕 Dermatitis herpetiformis
🧠 Brain fog
🤍 Infertility
Often missed for years ⏳
High suspicion = earlier dx = better outcomes ✅
bit.ly/45Wb4a5
😴 Fatigue
🩸 Iron-deficiency anaemia
🦴 Osteoporosis
🧪 Raised LFTs
⚡️ Neuropathy
🤕 Dermatitis herpetiformis
🧠 Brain fog
🤍 Infertility
Often missed for years ⏳
High suspicion = earlier dx = better outcomes ✅
bit.ly/45Wb4a5
Reposted by Nick Trott
Our MARCH ISSUE is live! Gut-brain axis, probiotics, HCC precision models and strategies, and much more!
www.nature.com/nrgastro/vol...
www.nature.com/nrgastro/vol...
February 28, 2025 at 8:10 AM
Our MARCH ISSUE is live! Gut-brain axis, probiotics, HCC precision models and strategies, and much more!
www.nature.com/nrgastro/vol...
www.nature.com/nrgastro/vol...
Immunology in Coeliac Disease.
T cells, APCs, B & epithelial cells drive CeD. The Exact immunologic sequence is unknown. HLA-DQ2 & DQ8 are essential. Without DQ2 and DQ8, CeD is (mostly) ruled out.
www.sciencedirect.com/science/arti...
T cells, APCs, B & epithelial cells drive CeD. The Exact immunologic sequence is unknown. HLA-DQ2 & DQ8 are essential. Without DQ2 and DQ8, CeD is (mostly) ruled out.
www.sciencedirect.com/science/arti...
February 28, 2025 at 5:05 PM
Immunology in Coeliac Disease.
T cells, APCs, B & epithelial cells drive CeD. The Exact immunologic sequence is unknown. HLA-DQ2 & DQ8 are essential. Without DQ2 and DQ8, CeD is (mostly) ruled out.
www.sciencedirect.com/science/arti...
T cells, APCs, B & epithelial cells drive CeD. The Exact immunologic sequence is unknown. HLA-DQ2 & DQ8 are essential. Without DQ2 and DQ8, CeD is (mostly) ruled out.
www.sciencedirect.com/science/arti...
Reposted by Nick Trott
Reposted by Nick Trott
Please find our latest paper on NGT feeding under restraint in England - the impact on parents and how nursing staff can support them.
journals.rcni.com/nursing-chil...
journals.rcni.com/nursing-chil...
Nasogastric tube feeding under physical restraint: understanding the effects on parents and how to support them
Nasogastric tube feeding under physical restraint: understanding the effects on parents and how to support them
journals.rcni.com
January 20, 2025 at 3:38 PM
Please find our latest paper on NGT feeding under restraint in England - the impact on parents and how nursing staff can support them.
journals.rcni.com/nursing-chil...
journals.rcni.com/nursing-chil...
Reposted by Nick Trott
Despite their prevalence and impact, persistent physical symptoms are often overlooked in medical care.
A call for action in Europe. As much needed in the US!
www.thelancet.com/journals/lan...
A call for action in Europe. As much needed in the US!
www.thelancet.com/journals/lan...
The overlooked burden of persistent physical symptoms: a call for action in European healthcare
Regardless of their cause, persistent physical symptoms are distressing somatic complaints
that occur on most days for at least several months. They are common in patients with
somatic diseases, funct...
www.thelancet.com
January 20, 2025 at 5:30 PM
Despite their prevalence and impact, persistent physical symptoms are often overlooked in medical care.
A call for action in Europe. As much needed in the US!
www.thelancet.com/journals/lan...
A call for action in Europe. As much needed in the US!
www.thelancet.com/journals/lan...
Reposted by Nick Trott
I’m delighted to report on behalf of all the authors that our research paper in Neurogastroenterology and Motility was selected for the: Award of Best Clinical Paper in NGM 2024.
pubmed.ncbi.nlm.nih.gov/39450680/
pubmed.ncbi.nlm.nih.gov/39450680/
Diagnostic classification systems for disorders of gut-brain interaction should include psychological symptoms - PubMed
Our data suggest that considering psychological as well as gastrointestinal symptoms would lead to a different clustering of individuals in more complex, and accurate, classification systems. For this...
pubmed.ncbi.nlm.nih.gov
December 21, 2024 at 12:27 AM
I’m delighted to report on behalf of all the authors that our research paper in Neurogastroenterology and Motility was selected for the: Award of Best Clinical Paper in NGM 2024.
pubmed.ncbi.nlm.nih.gov/39450680/
pubmed.ncbi.nlm.nih.gov/39450680/
Reposted by Nick Trott
Please find our latest paper on ngt feeding under restraint in England's paediatric wards
bmjopen.bmj.com/content/14/1...
bmjopen.bmj.com/content/14/1...
‘We are not trained to do clinical work’: security staff providing physical restraint for NGT feeding in English paediatric wards—a qualitative multi-informant study
Objective To gain insights into the experience, and impact, of using security staff to facilitate physical restraints for nasogastric tube feeding.
Design A cross-sectional design using 39 individual...
bmjopen.bmj.com
December 21, 2024 at 8:43 AM
Please find our latest paper on ngt feeding under restraint in England's paediatric wards
bmjopen.bmj.com/content/14/1...
bmjopen.bmj.com/content/14/1...
Reposted by Nick Trott
Amazing to watch commentators and outlets attribute these findings to UPFs and seed oils when the study doesn't even look at this. The assumption that eating more linoleic acid -> higher tissue arachidonic acid enrichment has fueled so many handwavey hypotheses despite metabolic regulation
December 14, 2024 at 3:08 AM
Amazing to watch commentators and outlets attribute these findings to UPFs and seed oils when the study doesn't even look at this. The assumption that eating more linoleic acid -> higher tissue arachidonic acid enrichment has fueled so many handwavey hypotheses despite metabolic regulation
Reposted by Nick Trott
International consensus statement on microbiome testing in clinical practice - just out in Lancet Gastro & Hepat www.sciencedirect.com/science/arti...
December 6, 2024 at 1:36 PM
International consensus statement on microbiome testing in clinical practice - just out in Lancet Gastro & Hepat www.sciencedirect.com/science/arti...
Reposted by Nick Trott
Letter sent in to the Editor of the Guardian on brain microbiome nonsense.
December 3, 2024 at 10:01 AM
Letter sent in to the Editor of the Guardian on brain microbiome nonsense.
Dietary legumes and the gut microbiome: a comprehensive review
🫘 Mixed effects on the microbiome
🫛 some studies showed ↑ diversity, others none.
🫘 Consistently ↑ beneficial species like Bifidobacterium & Faecalibacterium.
More standardized, long-term studies needed.
doi.org/10.1080/1040...
🫘 Mixed effects on the microbiome
🫛 some studies showed ↑ diversity, others none.
🫘 Consistently ↑ beneficial species like Bifidobacterium & Faecalibacterium.
More standardized, long-term studies needed.
doi.org/10.1080/1040...
December 2, 2024 at 9:20 PM
Dietary legumes and the gut microbiome: a comprehensive review
🫘 Mixed effects on the microbiome
🫛 some studies showed ↑ diversity, others none.
🫘 Consistently ↑ beneficial species like Bifidobacterium & Faecalibacterium.
More standardized, long-term studies needed.
doi.org/10.1080/1040...
🫘 Mixed effects on the microbiome
🫛 some studies showed ↑ diversity, others none.
🫘 Consistently ↑ beneficial species like Bifidobacterium & Faecalibacterium.
More standardized, long-term studies needed.
doi.org/10.1080/1040...
Reposted by Nick Trott
The #intestine's dynamics (environment/movement/stiffness/flow) shapes stem cell fitness and function, shown here via PIEZO channels and is reflected in in-vitro models. So, are static 3D cultures sufficient? Could microphysiological systems #MPS #Organ-on-chip offer a better approach here?
December 1, 2024 at 10:22 AM
The #intestine's dynamics (environment/movement/stiffness/flow) shapes stem cell fitness and function, shown here via PIEZO channels and is reflected in in-vitro models. So, are static 3D cultures sufficient? Could microphysiological systems #MPS #Organ-on-chip offer a better approach here?
Reposted by Nick Trott
How many gut microbes our gut holds may be more important than the species, new study suggests.
#microbes #microbial #BrainGutAxis
www.genengnews.com/topics/artif...
#microbes #microbial #BrainGutAxis
www.genengnews.com/topics/artif...
Machine Learning Reveals Impact of Microbial Load on Gut Health and Disease
New ML model shows importance of microbial load, as opposed to the more often used microbial composition, as a metric in microbiome research.
www.genengnews.com
November 26, 2024 at 8:05 PM
How many gut microbes our gut holds may be more important than the species, new study suggests.
#microbes #microbial #BrainGutAxis
www.genengnews.com/topics/artif...
#microbes #microbial #BrainGutAxis
www.genengnews.com/topics/artif...
New meta-analysis identifies accidental gluten exposure as primary cause of non-responsive coeliac disease. Underscores urgent need for improved support & greater access to specialist coeliac services for pts with persistent symptoms.
📄 onlinelibrary.wiley.com/doi/full/10....
📄 onlinelibrary.wiley.com/doi/full/10....
November 26, 2024 at 7:40 PM
New meta-analysis identifies accidental gluten exposure as primary cause of non-responsive coeliac disease. Underscores urgent need for improved support & greater access to specialist coeliac services for pts with persistent symptoms.
📄 onlinelibrary.wiley.com/doi/full/10....
📄 onlinelibrary.wiley.com/doi/full/10....
Practices of PCPs in Europe & the US in the Diagnosis & Tx of IBS: A Multinational Survey
- IBS underdiagnosed
- Viewed as diagnosis of exclusion
- US: confident in diets; EU: favor meds
- EU less ref for psych support
- Dr/Pt trust key to IBS care.
onlinelibrary.wiley.com/doi/10.1111/...
Perceptions and Practices of Primary Care Providers in Europe and the US in the Diagnosis and Treatment of Irritable Bowel Syndrome: A Multinational Survey
Rome Foundation criteria to support a positive diagnosis of IBS can guide PCPs, which is not a diagnosis of exclusion. PCPs can appropriately guide limited workups and institute both pharmacologic an...
onlinelibrary.wiley.com
November 22, 2024 at 11:11 AM
Practices of PCPs in Europe & the US in the Diagnosis & Tx of IBS: A Multinational Survey
- IBS underdiagnosed
- Viewed as diagnosis of exclusion
- US: confident in diets; EU: favor meds
- EU less ref for psych support
- Dr/Pt trust key to IBS care.
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Nick Trott
The 2024 ICDS Patient Forum is now live! Hear from experts on key topics like coeliac disease research, oats, treatments, and personal stories from Frankie, Nicola, Alan, & Frances.
Watch here: www.coeliac.org.uk/healthcare-p...
#CoeliacUK #CoeliacDisease #Coeliac #ICDSheff24 #ICDS24 #ICDS
Watch here: www.coeliac.org.uk/healthcare-p...
#CoeliacUK #CoeliacDisease #Coeliac #ICDSheff24 #ICDS24 #ICDS
November 21, 2024 at 10:08 AM
The 2024 ICDS Patient Forum is now live! Hear from experts on key topics like coeliac disease research, oats, treatments, and personal stories from Frankie, Nicola, Alan, & Frances.
Watch here: www.coeliac.org.uk/healthcare-p...
#CoeliacUK #CoeliacDisease #Coeliac #ICDSheff24 #ICDS24 #ICDS
Watch here: www.coeliac.org.uk/healthcare-p...
#CoeliacUK #CoeliacDisease #Coeliac #ICDSheff24 #ICDS24 #ICDS
Clinical outcomes of potential coeliac disease: a systematic review and meta-analysis:
- Aprox 16% of CeD is ? PCD
- 1/3 progress to CeD with gluten
- Many normalise serology
- Symptomatic PCD - GFD = 🥳
- More research needed
#CoeliacDisease
📄 gut.bmj.com/content/gutj...
- Aprox 16% of CeD is ? PCD
- 1/3 progress to CeD with gluten
- Many normalise serology
- Symptomatic PCD - GFD = 🥳
- More research needed
#CoeliacDisease
📄 gut.bmj.com/content/gutj...
November 19, 2024 at 6:15 PM
Clinical outcomes of potential coeliac disease: a systematic review and meta-analysis:
- Aprox 16% of CeD is ? PCD
- 1/3 progress to CeD with gluten
- Many normalise serology
- Symptomatic PCD - GFD = 🥳
- More research needed
#CoeliacDisease
📄 gut.bmj.com/content/gutj...
- Aprox 16% of CeD is ? PCD
- 1/3 progress to CeD with gluten
- Many normalise serology
- Symptomatic PCD - GFD = 🥳
- More research needed
#CoeliacDisease
📄 gut.bmj.com/content/gutj...
AOECS highlights the challenges of Gluten-Free Beer Testing.
🍺 Tests are evolving.
🍺 Beers <20 ppm - Safe.
🍺 Calls for clinical trials.
🍺 Trust the GF Symbol!
#Coeliac #GlutenFreeBeer
www.aoecs.org/news/aoecs-p...
🍺 Tests are evolving.
🍺 Beers <20 ppm - Safe.
🍺 Calls for clinical trials.
🍺 Trust the GF Symbol!
#Coeliac #GlutenFreeBeer
www.aoecs.org/news/aoecs-p...
November 18, 2024 at 5:58 PM
AOECS highlights the challenges of Gluten-Free Beer Testing.
🍺 Tests are evolving.
🍺 Beers <20 ppm - Safe.
🍺 Calls for clinical trials.
🍺 Trust the GF Symbol!
#Coeliac #GlutenFreeBeer
www.aoecs.org/news/aoecs-p...
🍺 Tests are evolving.
🍺 Beers <20 ppm - Safe.
🍺 Calls for clinical trials.
🍺 Trust the GF Symbol!
#Coeliac #GlutenFreeBeer
www.aoecs.org/news/aoecs-p...
Gluten Unraveled: Latest Insights on Terminology, Diagnosis, Pathophysiology, Dietary Strategies, & Intestinal Microbiota Modulations.
📃 www.mdpi.com/2072-6643/16...
📃 www.mdpi.com/2072-6643/16...
November 17, 2024 at 9:52 PM
Gluten Unraveled: Latest Insights on Terminology, Diagnosis, Pathophysiology, Dietary Strategies, & Intestinal Microbiota Modulations.
📃 www.mdpi.com/2072-6643/16...
📃 www.mdpi.com/2072-6643/16...