Gabriel Abrahams
@gabriel-abrahams.bsky.social
DPhil student in the Engineered Biotechnology Group, University of Oxford. https://steel.ac/
ORCID: 0000-0002-2360-7150
ORCID: 0000-0002-2360-7150
Pinned
MagLOV quantum sensing update! Much improved imaging (>10% single cell ODMR contrast), detailed characterisation and simulation, and new experimental demonstrations taking us a step closer to applications.
www.biorxiv.org/content/10.1...
SI: www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
SI: www.biorxiv.org/content/10.1...
Reposted by Gabriel Abrahams
1 week left to apply for a postdoctoral position in my group to lead the experimental component of a 5 year BBSRC project on synthetic microbial communities
www.ucl.ac.uk/work-at-ucl/...
www.ucl.ac.uk/work-at-ucl/...
October 20, 2025 at 9:49 AM
1 week left to apply for a postdoctoral position in my group to lead the experimental component of a 5 year BBSRC project on synthetic microbial communities
www.ucl.ac.uk/work-at-ucl/...
www.ucl.ac.uk/work-at-ucl/...
Reposted by Gabriel Abrahams
Generative design of synthetic gene circuits for functional and evolutionary properties https://www.biorxiv.org/content/10.1101/2025.09.26.678595v1
September 28, 2025 at 3:03 AM
Generative design of synthetic gene circuits for functional and evolutionary properties https://www.biorxiv.org/content/10.1101/2025.09.26.678595v1
Reposted by Gabriel Abrahams
🚨 We’re hiring!
The OPIG group is looking for multiple postdocs to join OpenBind, an open science initiative generating foundational structural biology data to power the next era of AI/ML for drug discovery.
opig.stats.ox.ac.uk
openbind.uk
The OPIG group is looking for multiple postdocs to join OpenBind, an open science initiative generating foundational structural biology data to power the next era of AI/ML for drug discovery.
opig.stats.ox.ac.uk
openbind.uk
OpenBind
openbind.uk
September 17, 2025 at 4:05 PM
🚨 We’re hiring!
The OPIG group is looking for multiple postdocs to join OpenBind, an open science initiative generating foundational structural biology data to power the next era of AI/ML for drug discovery.
opig.stats.ox.ac.uk
openbind.uk
The OPIG group is looking for multiple postdocs to join OpenBind, an open science initiative generating foundational structural biology data to power the next era of AI/ML for drug discovery.
opig.stats.ox.ac.uk
openbind.uk
Reposted by Gabriel Abrahams
We’ve developed the first-ever method to control nucleic acid activity and gene-expressing synthetic cells with a deeply tissue penetrating alternating magnetic field 🧬 🧪 🧲!!!
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells - Nature Chemistry
The programmability of synthetic cells, comprising lipid vesicles that are capable of imitating the structure and function of living cells, facilitates their application as drug delivery devices. Now,...
www.nature.com
September 2, 2025 at 9:31 AM
We’ve developed the first-ever method to control nucleic acid activity and gene-expressing synthetic cells with a deeply tissue penetrating alternating magnetic field 🧬 🧪 🧲!!!
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
MagLOV quantum sensing update! Much improved imaging (>10% single cell ODMR contrast), detailed characterisation and simulation, and new experimental demonstrations taking us a step closer to applications.
www.biorxiv.org/content/10.1...
SI: www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
SI: www.biorxiv.org/content/10.1...
August 21, 2025 at 1:59 PM
MagLOV quantum sensing update! Much improved imaging (>10% single cell ODMR contrast), detailed characterisation and simulation, and new experimental demonstrations taking us a step closer to applications.
www.biorxiv.org/content/10.1...
SI: www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
SI: www.biorxiv.org/content/10.1...
Reposted by Gabriel Abrahams
Now out in JACS. pubs.acs.org/doi/full/10....
Grateful to thoughtful reviewers who found some errors in our model and encouraged us to make a better one! A renaissance in magnetobiology is coming...
Grateful to thoughtful reviewers who found some errors in our model and encouraged us to make a better one! A renaissance in magnetobiology is coming...
May 15, 2025 at 4:04 PM
Now out in JACS. pubs.acs.org/doi/full/10....
Grateful to thoughtful reviewers who found some errors in our model and encouraged us to make a better one! A renaissance in magnetobiology is coming...
Grateful to thoughtful reviewers who found some errors in our model and encouraged us to make a better one! A renaissance in magnetobiology is coming...
Reposted by Gabriel Abrahams
My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty
April 8, 2025 at 8:06 AM
My lab at @ethzurich.bsky.social is looking for a motivated PhD student. We develop chemical tools for advanced fluorescence microscopy 🔬 and work at the interface of synthetic chemistry ⚗️ and protein engineering 🦠. Sharing with skilled Master students appreciated. More info at tinyurl.com/2dbjk5ty
Reposted by Gabriel Abrahams
NEW PREPRINT! Do you think we can do better when characterising resource competition properties of gene circuit modules? If no, think again; if yes, you’re in for a pitch how exactly we can do that – automated culturing, cybergenetic control and all! 1/
doi.org/10.1101/2025...
doi.org/10.1101/2025...
April 4, 2025 at 9:22 AM
NEW PREPRINT! Do you think we can do better when characterising resource competition properties of gene circuit modules? If no, think again; if yes, you’re in for a pitch how exactly we can do that – automated culturing, cybergenetic control and all! 1/
doi.org/10.1101/2025...
doi.org/10.1101/2025...
New spin resonance measurements with fluorescent proteins out this month from Burd et al., following the still mind-blowing result from @andrewgyork.bsky.social and @mariaingaramo.bsky.social that if you create a selection pressure for a quantum system, nature will oblige! 🧪
March 14, 2025 at 10:48 AM
New spin resonance measurements with fluorescent proteins out this month from Burd et al., following the still mind-blowing result from @andrewgyork.bsky.social and @mariaingaramo.bsky.social that if you create a selection pressure for a quantum system, nature will oblige! 🧪
Reposted by Gabriel Abrahams
New preprint 🎇 We developed oligonucleotide PROTACs (OligoPROTACs), which show comparable activity to small molecule equivalents - but can be *switched off*, using DNA nanotech, to restore protein levels!
Last of Disha's trilogy!
#chemsky 🧪 @uclchemistry.bsky.social chemrxiv.org/engage/chemr...
Last of Disha's trilogy!
#chemsky 🧪 @uclchemistry.bsky.social chemrxiv.org/engage/chemr...
DNA-programmable Protein Degradation: Dynamic Control of PROTAC Activity via DNA Hybridization and Strand Displacement
Targeted protein degradation is a powerful therapeutic approach: expanding the druggable proteome, providing enhanced selectivity, and having the ability to overcome conventional resistance mechanisms...
chemrxiv.org
March 12, 2025 at 9:16 AM
New preprint 🎇 We developed oligonucleotide PROTACs (OligoPROTACs), which show comparable activity to small molecule equivalents - but can be *switched off*, using DNA nanotech, to restore protein levels!
Last of Disha's trilogy!
#chemsky 🧪 @uclchemistry.bsky.social chemrxiv.org/engage/chemr...
Last of Disha's trilogy!
#chemsky 🧪 @uclchemistry.bsky.social chemrxiv.org/engage/chemr...
Reposted by Gabriel Abrahams
How do tiny magnetic fields affect biochemistry? Overflowing with pride over Katherine Xiang's study on a giant magnetic field effect in a red fluorescent protein, www.biorxiv.org/content/10.1...
Mechanism of giant magnetic field effect in fluorescence of mScarlet3, a red fluorescent protein
Several fluorescent proteins, when expressed in E. coli, are sensitive to weak magnetic fields1. We found that mScarlet3 fluorescence in E. coli reversibly decreased by 21% in the presence of a 60 mT ...
www.biorxiv.org
February 28, 2025 at 4:00 PM
How do tiny magnetic fields affect biochemistry? Overflowing with pride over Katherine Xiang's study on a giant magnetic field effect in a red fluorescent protein, www.biorxiv.org/content/10.1...
Reposted by Gabriel Abrahams
Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!
February 21, 2025 at 8:42 PM
Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!
Reposted by Gabriel Abrahams
Bravo @plos.org!
US exec orders "stand in direct conflict with our core values, our mission, edit policies"
"PLOS will not compromise on issues of scientific rigor & editorial integrity... we seek diversity because more expert voices make for better science"
theplosblog.plos.org/2025/02/plos...
US exec orders "stand in direct conflict with our core values, our mission, edit policies"
"PLOS will not compromise on issues of scientific rigor & editorial integrity... we seek diversity because more expert voices make for better science"
theplosblog.plos.org/2025/02/plos...
PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog
Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…
theplosblog.plos.org
February 21, 2025 at 2:45 PM
Bravo @plos.org!
US exec orders "stand in direct conflict with our core values, our mission, edit policies"
"PLOS will not compromise on issues of scientific rigor & editorial integrity... we seek diversity because more expert voices make for better science"
theplosblog.plos.org/2025/02/plos...
US exec orders "stand in direct conflict with our core values, our mission, edit policies"
"PLOS will not compromise on issues of scientific rigor & editorial integrity... we seek diversity because more expert voices make for better science"
theplosblog.plos.org/2025/02/plos...
Reposted by Gabriel Abrahams
Experimental evolution of evolvability | Science www.science.org/doi/10.1126/...
Experimental evolution of evolvability
Evolvability—the capacity to generate adaptive variation—is a trait that can itself evolve through natural selection. However, the idea that mutation can become biased toward adaptive outcomes remains...
www.science.org
February 20, 2025 at 9:16 PM
Experimental evolution of evolvability | Science www.science.org/doi/10.1126/...
Reposted by Gabriel Abrahams
This Valentine's day I want to share the LOV2 with you! ❤️
Roses are red,
the light is blue,
stimuli are read
by the domain LOV2.
Roses are red,
the light is blue,
stimuli are read
by the domain LOV2.
February 14, 2025 at 5:25 PM
This Valentine's day I want to share the LOV2 with you! ❤️
Roses are red,
the light is blue,
stimuli are read
by the domain LOV2.
Roses are red,
the light is blue,
stimuli are read
by the domain LOV2.
My lab does cool stuff 👇
Our paper on countering mutations in engineered cell populations has now been published with @royalsocietypublishing.org ! Come for our biomolecular controller that mitigates mutation spread, stay for resource-aware gene circuit design and modelling tools 1/10
doi.org/10.1098/rsif.2024.0602
doi.org/10.1098/rsif.2024.0602
February 13, 2025 at 1:28 PM
My lab does cool stuff 👇
Reposted by Gabriel Abrahams
Looking for a #PhD that is at the intersection of #biodesign, #synbio, #openendedness, #evolution? Look no further. Great supervisory team too 😉
February 1, 2025 at 4:08 AM
Looking for a #PhD that is at the intersection of #biodesign, #synbio, #openendedness, #evolution? Look no further. Great supervisory team too 😉
Reposted by Gabriel Abrahams
Two weeks to go until the application deadline for ILESLA. If you or anyone you know would benefit from full funding to carry out a PhD in Life and/or Environmental Science please visit/refer to our website page iles.web.ox.ac.uk/how-apply where you can see open day videos and get full guidance.
How to Apply and Funding
iles.web.ox.ac.uk
January 16, 2025 at 2:10 PM
Two weeks to go until the application deadline for ILESLA. If you or anyone you know would benefit from full funding to carry out a PhD in Life and/or Environmental Science please visit/refer to our website page iles.web.ox.ac.uk/how-apply where you can see open day videos and get full guidance.
Reposted by Gabriel Abrahams
Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇
May 20, 2024 at 2:19 PM
Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇
Reposted by Gabriel Abrahams
The one time @theguardian.com could rightly use a left-handed DNA image... and they choose right-handed 🤦🏻♂️🤦🏻♂️🤦🏻♂️
@iansample.bsky.social
@iansample.bsky.social
December 13, 2024 at 8:18 AM
The one time @theguardian.com could rightly use a left-handed DNA image... and they choose right-handed 🤦🏻♂️🤦🏻♂️🤦🏻♂️
@iansample.bsky.social
@iansample.bsky.social
Reposted by Gabriel Abrahams
Reflecting on the two days of #sbuk24 talks on the very slow journey home, I think my favourite was Scott Stacey from Harrison Steel's group.
Lovely demonstration of complexity built from simple biology that needs modelling to fully understand an unexpected result
Lovely demonstration of complexity built from simple biology that needs modelling to fully understand an unexpected result
November 28, 2024 at 8:09 PM
Reflecting on the two days of #sbuk24 talks on the very slow journey home, I think my favourite was Scott Stacey from Harrison Steel's group.
Lovely demonstration of complexity built from simple biology that needs modelling to fully understand an unexpected result
Lovely demonstration of complexity built from simple biology that needs modelling to fully understand an unexpected result
Reposted by Gabriel Abrahams
Goooo @georgiehs.bsky.social!
Georgie Hau Sorensen introduces a tool for inserting dogtags into proteins to allow more control over binding of accessory proteins e.g. deaminase bound to polymerase #sbuk24
November 28, 2024 at 4:34 PM
Goooo @georgiehs.bsky.social!
Reposted by Gabriel Abrahams
Day 2 of #sbuk24 starts with a session on control opened by Harrison Steel. Lots of excellent stuff (as usual), from directed evolution in microfluidics to "magnetogenetics"
November 28, 2024 at 9:59 AM
Day 2 of #sbuk24 starts with a session on control opened by Harrison Steel. Lots of excellent stuff (as usual), from directed evolution in microfluidics to "magnetogenetics"