Thomas Gorochowski
@chofski.bsky.social
Synthetic biologist, programmer of cells, and lover of all things visual. Wakes up in the morning to learn some of natures secrets and do a spot of fly fishing.
Reposted by Thomas Gorochowski
Many microorganisms modify their movement in response to light. This new #JRSocInterface paper has developed an integrated pipeline capable of acquiring temporal imaging data and extracting kinematics to create digital twins: doi.org/10.1098/rsif... @chofski.bsky.social
February 5, 2026 at 1:01 PM
Many microorganisms modify their movement in response to light. This new #JRSocInterface paper has developed an integrated pipeline capable of acquiring temporal imaging data and extracting kinematics to create digital twins: doi.org/10.1098/rsif... @chofski.bsky.social
🫣 Now for something a little different from the lab: a data-centric approach to building digital twins as a route to control of emergent population level behaviours in microbial swarms 🤔 If that means nothing to you, then just check out the video! doi.org/10.1098/rsif... #engbio #control
January 28, 2026 at 12:24 PM
🫣 Now for something a little different from the lab: a data-centric approach to building digital twins as a route to control of emergent population level behaviours in microbial swarms 🤔 If that means nothing to you, then just check out the video! doi.org/10.1098/rsif... #engbio #control
Reposted by Thomas Gorochowski
Next in Lab's conference agenda: AI, Engineering Biology and beyond. It starts today in Bristol hosted by @chofski.bsky.social. Looks great: aiebab.github.io. From our side, @lewisgrozinger.bsky.social will be talking about our approach to the use of evolutionary algorithms for biocomputation.
AIEBaB-2026
aiebab.github.io
January 15, 2026 at 9:51 AM
Next in Lab's conference agenda: AI, Engineering Biology and beyond. It starts today in Bristol hosted by @chofski.bsky.social. Looks great: aiebab.github.io. From our side, @lewisgrozinger.bsky.social will be talking about our approach to the use of evolutionary algorithms for biocomputation.
So happy you could come!
January 15, 2026 at 6:39 AM
So happy you could come!
Reposted by Thomas Gorochowski
In Bristol for the week for the AI, Engineering Biology and Beyond conference hosted by @chofski.bsky.social. Very excited to meet the UK synthbio community. First day hackathon event was a blast!
January 14, 2026 at 11:54 PM
In Bristol for the week for the AI, Engineering Biology and Beyond conference hosted by @chofski.bsky.social. Very excited to meet the UK synthbio community. First day hackathon event was a blast!
It's so cute! All credit to Shiv the lead author for devising the name.
January 14, 2026 at 12:40 PM
It's so cute! All credit to Shiv the lead author for devising the name.
Cold and "nippy" 🥶 start to the #AIEBaB26 Hack-a-thon 💻. The students helping with the organisation have done an amazing job in pulling this all together. A big thank you to the @jgibristol.bsky.social and @aibio-uk.bsky.social for the support!
January 14, 2026 at 10:02 AM
Cold and "nippy" 🥶 start to the #AIEBaB26 Hack-a-thon 💻. The students helping with the organisation have done an amazing job in pulling this all together. A big thank you to the @jgibristol.bsky.social and @aibio-uk.bsky.social for the support!
If you work with R6K plasmids for transient DNA delivery, our latest SHARK strains might be of use! Work out at ACS Synthetic Biology led by Shivang Joshi and strains plus plasmids for their assembly will be available @addgene.bsky.social very soon! doi.org/10.1021/acss...
January 14, 2026 at 7:01 AM
If you work with R6K plasmids for transient DNA delivery, our latest SHARK strains might be of use! Work out at ACS Synthetic Biology led by Shivang Joshi and strains plus plasmids for their assembly will be available @addgene.bsky.social very soon! doi.org/10.1021/acss...
If you are looking to integrate your latest genetic creation into the genome of your favourite bug, you might find our latest review now out in OUP Synthetic Biology useful. 🧬⚒️ Work led by Riesa Rohmat with input from Thea Irvine and Shivang Joshi. #genome #synbio doi.org/10.1093/synb...
January 6, 2026 at 10:58 AM
If you are looking to integrate your latest genetic creation into the genome of your favourite bug, you might find our latest review now out in OUP Synthetic Biology useful. 🧬⚒️ Work led by Riesa Rohmat with input from Thea Irvine and Shivang Joshi. #genome #synbio doi.org/10.1093/synb...
Reposted by Thomas Gorochowski
So you think your mammalian plasmids have nothing to fear from cloning and propagation in E.coli?
Quantitative profiling of millions of nucleotides by Tom Copeman will prove you wrong! Supervised with the amazing @proftomellis.bsky.social and AZ, now on BioRxiv:
doi.org/10.64898/202...
Quantitative profiling of millions of nucleotides by Tom Copeman will prove you wrong! Supervised with the amazing @proftomellis.bsky.social and AZ, now on BioRxiv:
doi.org/10.64898/202...
Quantitative profiling of millions of nucleotides reveals sequence-encoded interactions that govern plasmid propagation
Plasmids are central to modern biotechnology, especially therapeutic development, yet their propagation in Escherichia coli remains difficult to predict. Although expression-induced burden is well und...
doi.org
December 17, 2025 at 8:19 AM
So you think your mammalian plasmids have nothing to fear from cloning and propagation in E.coli?
Quantitative profiling of millions of nucleotides by Tom Copeman will prove you wrong! Supervised with the amazing @proftomellis.bsky.social and AZ, now on BioRxiv:
doi.org/10.64898/202...
Quantitative profiling of millions of nucleotides by Tom Copeman will prove you wrong! Supervised with the amazing @proftomellis.bsky.social and AZ, now on BioRxiv:
doi.org/10.64898/202...
Reposted by Thomas Gorochowski
Emerging trends in genome integration tools for precision engineering of diverse bacterial species
doi.org/10.1093/synb...
doi.org/10.1093/synb...
Emerging trends in genome integration tools for precision engineering of diverse bacterial species
Abstract. The ability to precisely insert DNA payloads into a genome enables the comprehensive engineering of cellular phenotypes and the creation of new b
doi.org
December 15, 2025 at 1:27 PM
Emerging trends in genome integration tools for precision engineering of diverse bacterial species
doi.org/10.1093/synb...
doi.org/10.1093/synb...
🚨 Last call for the 'AI, Engineering Biology and Beyond' conference taking place in Bristol on the 15-16 January 2026. There is a limited capacity and some places are still left, but worth signing up soon before the 19th December deadline! Register at: aiebab.github.io
December 10, 2025 at 8:49 PM
🚨 Last call for the 'AI, Engineering Biology and Beyond' conference taking place in Bristol on the 15-16 January 2026. There is a limited capacity and some places are still left, but worth signing up soon before the 19th December deadline! Register at: aiebab.github.io
📕My review for Jane Calvert's latest book, 'A Place for Science and Technology Studies' is out in Interdisciplinary Science Reviews! I really enjoyed the stories and learnt so mcuh. Well worth a read if you are interested in the ways that that study of science works: doi.org/10.1177/0308...
December 10, 2025 at 1:27 PM
📕My review for Jane Calvert's latest book, 'A Place for Science and Technology Studies' is out in Interdisciplinary Science Reviews! I really enjoyed the stories and learnt so mcuh. Well worth a read if you are interested in the ways that that study of science works: doi.org/10.1177/0308...
End of year Science Bonanza is always something I look forward to, not only for hearing about what the team has been up to all year, but also for the amazing food everyone brings. Christmas has started proper now 🎅
December 9, 2025 at 7:44 PM
End of year Science Bonanza is always something I look forward to, not only for hearing about what the team has been up to all year, but also for the amazing food everyone brings. Christmas has started proper now 🎅
Only available to UK applicants, and did I mention these studentships are part of the TechExpert pilot providing an enhanced annual (tax-free) stipend of £31,000. Do something amazing, and get paid for it!
December 2, 2025 at 10:24 PM
Only available to UK applicants, and did I mention these studentships are part of the TechExpert pilot providing an enhanced annual (tax-free) stipend of £31,000. Do something amazing, and get paid for it!
(PhD 2) Join Heather Whitney, me and others to take plant RNA synthetic biology to a new level. Create new biofacbrication processes to enable the robust and effective RNA delivery to turbo-charge agriculture. 3/4 www.findaphd.com/phds/project...
Optimising a platform for RNA delivery in plants (Plant BioDesign Bristol project) at University of York on FindAPhD.com
PhD Project - Optimising a platform for RNA delivery in plants (Plant BioDesign Bristol project) at University of York, listed on FindAPhD.com
www.findaphd.com
December 2, 2025 at 10:24 PM
(PhD 2) Join Heather Whitney, me and others to take plant RNA synthetic biology to a new level. Create new biofacbrication processes to enable the robust and effective RNA delivery to turbo-charge agriculture. 3/4 www.findaphd.com/phds/project...
(PhD 1) Join @PierreBuscaill and me to create SynProm, a modular synthetic biology toolkit for rapid, spatio-temporal monitoring of plant gene activity. Design, test & model synthetic promoters in Nicotiana benthamiana with a focus on plant immunity. 2/4 www.findaphd.com/phds/project...
SynProm: Fast, Modular Spatio-Temporal Transcriptional Reporters for Plants (Plant BioDesign Bristol project) at University of York on FindAPhD.com
PhD Project - SynProm: Fast, Modular Spatio-Temporal Transcriptional Reporters for Plants (Plant BioDesign Bristol project) at University of York, listed on FindAPhD.com
www.findaphd.com
December 2, 2025 at 10:24 PM
(PhD 1) Join @PierreBuscaill and me to create SynProm, a modular synthetic biology toolkit for rapid, spatio-temporal monitoring of plant gene activity. Design, test & model synthetic promoters in Nicotiana benthamiana with a focus on plant immunity. 2/4 www.findaphd.com/phds/project...
Very excited for this project with @pierrebuscaill.bsky.social! Will bring together a lot of exciting tools we have up and running in the lab for working with diverse biology and put them to use in building new technologies to trace gene expression across plants. 🧬 🔍 Applications open!
🚀 PhD opportunity!
Join us (@pierrebuscaill.bsky.social & @chofski.bsky.social) in Bristol 🌱✨ Design, test & model synthetic promoters in Nicotiana benthamiana, focusing on plant immunity. Apply now!
🔗 www.findaphd.com/phds/project...
#PlantSci #SyntheticBiology #PhD #PlantBioDesign #BristolUni
Join us (@pierrebuscaill.bsky.social & @chofski.bsky.social) in Bristol 🌱✨ Design, test & model synthetic promoters in Nicotiana benthamiana, focusing on plant immunity. Apply now!
🔗 www.findaphd.com/phds/project...
#PlantSci #SyntheticBiology #PhD #PlantBioDesign #BristolUni
SynProm: Fast, Modular Spatio-Temporal Transcriptional Reporters for Plants (Plant BioDesign Bristol project) at University of York on FindAPhD.com
PhD Project - SynProm: Fast, Modular Spatio-Temporal Transcriptional Reporters for Plants (Plant BioDesign Bristol project) at University of York, listed on FindAPhD.com
www.findaphd.com
December 2, 2025 at 5:59 PM
Very excited for this project with @pierrebuscaill.bsky.social! Will bring together a lot of exciting tools we have up and running in the lab for working with diverse biology and put them to use in building new technologies to trace gene expression across plants. 🧬 🔍 Applications open!
The initial lineup of keynotes and spotlight talks is finalised, with 10 contributed talks still up for grabs! Come join us in Bristol on 15-16 Jan 2026 for AI, Engineering Biology and Beyond to shape the future of these fields🤖🧬🦠Register now at: aiebab.github.io
November 20, 2025 at 9:52 AM
The initial lineup of keynotes and spotlight talks is finalised, with 10 contributed talks still up for grabs! Come join us in Bristol on 15-16 Jan 2026 for AI, Engineering Biology and Beyond to shape the future of these fields🤖🧬🦠Register now at: aiebab.github.io
🚨Interested in the intersection of AI and Engineering Biology? 🤖🧬 If so, come join us in Bristol, UK from 15-16 Jan 2026 for the latest instalment of the "AI, Engineering Biology and Beyond" conference! It's going to be a "banger" and registration is open NOW! #synbio #ai aiebab.github.io
October 22, 2025 at 10:03 AM
🚨Interested in the intersection of AI and Engineering Biology? 🤖🧬 If so, come join us in Bristol, UK from 15-16 Jan 2026 for the latest instalment of the "AI, Engineering Biology and Beyond" conference! It's going to be a "banger" and registration is open NOW! #synbio #ai aiebab.github.io
Reposted by Thomas Gorochowski
Université Grenoble Alpes opens a full professorship in microbiology in 2026. The selected candidate will develop their research program on quantitative approaches in microbiology in the Laboratoire Interdisciplinaire de Physique. More info: liphy.univ-grenoble-alpes.fr/en/join-us/r...
Professorship (tenure) in 'Quantitative approaches in microbiology' (CNU Sections 64/65) | LIPhy - Université Grenoble Alpes
liphy.univ-grenoble-alpes.fr
October 7, 2025 at 1:19 PM
Université Grenoble Alpes opens a full professorship in microbiology in 2026. The selected candidate will develop their research program on quantitative approaches in microbiology in the Laboratoire Interdisciplinaire de Physique. More info: liphy.univ-grenoble-alpes.fr/en/join-us/r...
Reposted by Thomas Gorochowski
SHARK: a specialized host for assembling R6K plasmids https://www.biorxiv.org/content/10.1101/2025.10.06.680659v1
October 7, 2025 at 4:11 AM
SHARK: a specialized host for assembling R6K plasmids https://www.biorxiv.org/content/10.1101/2025.10.06.680659v1
Reposted by Thomas Gorochowski
SHARK: a specialized host for assembling R6K plasmids
doi.org/10.1101/2025...
doi.org/10.1101/2025...
October 7, 2025 at 7:02 AM
SHARK: a specialized host for assembling R6K plasmids
doi.org/10.1101/2025...
doi.org/10.1101/2025...