Thomas Gorochowski
@chofski.bsky.social
Synthetic biologist, programmer of cells, and lover of all things visual. Wakes up in the morning to learn some of natures secrets and do a spot of fly fishing.
🚨Interested in the intersection of AI and Engineering Biology? 🤖🧬 If so, come join us in Bristol, UK from 15-16 Jan 2026 for the latest instalment of the "AI, Engineering Biology and Beyond" conference! It's going to be a "banger" and registration is open NOW! #synbio #ai aiebab.github.io
October 22, 2025 at 10:03 AM
🚨Interested in the intersection of AI and Engineering Biology? 🤖🧬 If so, come join us in Bristol, UK from 15-16 Jan 2026 for the latest instalment of the "AI, Engineering Biology and Beyond" conference! It's going to be a "banger" and registration is open NOW! #synbio #ai aiebab.github.io
🛠️New tool from the lab! #SHARK🦈: a new strain to support complex cloning of transient R6K expression plasmids – perfect for genome engineering. Work led by the talented Shivang Joshi and all strains and strain assembly tools enroute to Addgene. #synbio doi.org/10.1101/2025...
October 7, 2025 at 8:31 AM
🛠️New tool from the lab! #SHARK🦈: a new strain to support complex cloning of transient R6K expression plasmids – perfect for genome engineering. Work led by the talented Shivang Joshi and all strains and strain assembly tools enroute to Addgene. #synbio doi.org/10.1101/2025...
🥳Excited to share our latest collaborative work using whole-cell models and #AI to design genomes!🦠🧬 What a time to be alive! Project led by Ioana Gherman, with Kieren Sharma, Joshua Rees-Garbutt, Claire Grierson, Lucia Marucci, Wei Pang & Zahraa Abdallah #synbio authors.elsevier.com/sd/article/S...
September 24, 2025 at 5:25 PM
🥳Excited to share our latest collaborative work using whole-cell models and #AI to design genomes!🦠🧬 What a time to be alive! Project led by Ioana Gherman, with Kieren Sharma, Joshua Rees-Garbutt, Claire Grierson, Lucia Marucci, Wei Pang & Zahraa Abdallah #synbio authors.elsevier.com/sd/article/S...
Very excited to attend and speak at this years #UKOMAIN Multimodal AI workshop at the Barbican. Already learning a lot about emulators and generative models for novel materials.
September 16, 2025 at 9:24 AM
Very excited to attend and speak at this years #UKOMAIN Multimodal AI workshop at the Barbican. Already learning a lot about emulators and generative models for novel materials.
🚨I have a fully funded 4-year #PhD opportunity in my lab on 'Tuneable multi-input genetic logic circuits for designer probiotics'.🦠 We'll be throwing all the tech we have at this one to make reliable engineering of diverse microbes a reality. Applicants must be UK national...
September 3, 2025 at 9:00 AM
🚨I have a fully funded 4-year #PhD opportunity in my lab on 'Tuneable multi-input genetic logic circuits for designer probiotics'.🦠 We'll be throwing all the tech we have at this one to make reliable engineering of diverse microbes a reality. Applicants must be UK national...
Come and join us at a free complementary Japan-UK Engineering Biology meeting after the main ESSL conference (essl2025.org/). A few spaces left to some see some of the up and coming superstars of #synbio in the UK!
September 1, 2025 at 8:31 PM
Come and join us at a free complementary Japan-UK Engineering Biology meeting after the main ESSL conference (essl2025.org/). A few spaces left to some see some of the up and coming superstars of #synbio in the UK!
Standard day in Bristol... balloons!
August 12, 2025 at 12:27 PM
Standard day in Bristol... balloons!
Reading some wonderful old Russian mathematics on automata theory and love this comment that just popped up! Coming from the rural countryside of Somerset, I'm not sure the people quite match this analysis! 🤠
August 7, 2025 at 6:19 PM
Reading some wonderful old Russian mathematics on automata theory and love this comment that just popped up! Coming from the rural countryside of Somerset, I'm not sure the people quite match this analysis! 🤠
Although I've now taken a back seat, it is great to see the growing adoption of SBOL Visual in the synthetic and engineering biology literature and even more awesome to see so many current and visiting students to my lab on the author list😍 Roll on 2035! arxiv.org/abs/2507.04601
July 8, 2025 at 12:53 PM
Although I've now taken a back seat, it is great to see the growing adoption of SBOL Visual in the synthetic and engineering biology literature and even more awesome to see so many current and visiting students to my lab on the author list😍 Roll on 2035! arxiv.org/abs/2507.04601
What to agument your favourite protein with new functionalities? 🛠️ We've got a #biodesign workflow to help with that! In work led by @georgiehs.bsky.social we present SIMPLIFE that blends biophyscial and #ML models to extend biology in useful ways. #synbio doi.org/10.1101/2025...
June 23, 2025 at 8:43 AM
What to agument your favourite protein with new functionalities? 🛠️ We've got a #biodesign workflow to help with that! In work led by @georgiehs.bsky.social we present SIMPLIFE that blends biophyscial and #ML models to extend biology in useful ways. #synbio doi.org/10.1101/2025...
Some days I’m reminded of why working in research can be so exciting. Imaging DNA at the sub-nanometre scale on this beast! High-speed scanning #AFM for the win.
June 4, 2025 at 3:52 PM
Some days I’m reminded of why working in research can be so exciting. Imaging DNA at the sub-nanometre scale on this beast! High-speed scanning #AFM for the win.
Recombinases your thing? In the latest from my lab, Veronica Greco shows how @nanopore sequencing + automated liquid handling provides the perfect platform for characterising these systems at scale! Awesome collaboration with @jennbrophy.bsky.social @sarah-guiziou.bsky.social doi.org/10.1101/2025...
May 29, 2025 at 6:49 AM
Recombinases your thing? In the latest from my lab, Veronica Greco shows how @nanopore sequencing + automated liquid handling provides the perfect platform for characterising these systems at scale! Awesome collaboration with @jennbrophy.bsky.social @sarah-guiziou.bsky.social doi.org/10.1101/2025...
Had an awesome time at #IEEE #ASYNC2025 this year in the beautiful Portland OR. Such a vibrant and open community. Thanks to the organisers. Hopefully this is the start of some new intersections between asynchronous circuits and engineered biology!
May 15, 2025 at 3:47 PM
Had an awesome time at #IEEE #ASYNC2025 this year in the beautiful Portland OR. Such a vibrant and open community. Thanks to the organisers. Hopefully this is the start of some new intersections between asynchronous circuits and engineered biology!
Awesome visit to @royalsociety.org to see some of the treasures in their collection, followed up by a fun session with some of the Imperial #synbio "crew" feat. @proftomellis.bsky.social @ceronifranci.bsky.social Ouldridge Lab. Highlights were Micrographia and the TODO list of the early fellowship!
April 25, 2025 at 8:21 AM
Awesome visit to @royalsociety.org to see some of the treasures in their collection, followed up by a fun session with some of the Imperial #synbio "crew" feat. @proftomellis.bsky.social @ceronifranci.bsky.social Ouldridge Lab. Highlights were Micrographia and the TODO list of the early fellowship!
Learn how Cas9-enrichment + @nanoporetech.com sequencing can more fully uncover biodiversity in complex environments via targeted metabarcoding in latest from lab! Led by the hugely talented Lucia Nikolaeva-Reynolds who started this as her final year undergraduate project! doi.org/10.1098/rsos...
April 23, 2025 at 6:51 AM
Learn how Cas9-enrichment + @nanoporetech.com sequencing can more fully uncover biodiversity in complex environments via targeted metabarcoding in latest from lab! Led by the hugely talented Lucia Nikolaeva-Reynolds who started this as her final year undergraduate project! doi.org/10.1098/rsos...
Looking for a PhD? I have a fully funded one for UK nationals on engineering gene circuits in probiotic microbes. Will bring together a lot of existing stands of #synbio research in my group and push towards some exciting applications! Start date Sept 2025. Email me if interested! Pls RT
March 28, 2025 at 1:08 PM
Looking for a PhD? I have a fully funded one for UK nationals on engineering gene circuits in probiotic microbes. Will bring together a lot of existing stands of #synbio research in my group and push towards some exciting applications! Start date Sept 2025. Email me if interested! Pls RT
Phenotyping motile microorganisms is always a challenge. In the latest from the lab led by Andrea Giusti, we show how our #DOME platform can speed up the processes, enabling data-centric inference of digital twins and routes to multicellular control! 🦠💨🔦 doi.org/10.1101/2025...
February 27, 2025 at 3:43 PM
Phenotyping motile microorganisms is always a challenge. In the latest from the lab led by Andrea Giusti, we show how our #DOME platform can speed up the processes, enabling data-centric inference of digital twins and routes to multicellular control! 🦠💨🔦 doi.org/10.1101/2025...
That's all folks 🐰 Time for sake, sushi and sleep! #japanuksynbio
February 4, 2025 at 7:38 AM
That's all folks 🐰 Time for sake, sushi and sleep! #japanuksynbio
Moe Yabuta is now speaking about self-growing protocell models in aqueous two-phase system induced by internal DNA replication reaction. Beautiful talk by a PhD student... one to watch! #japanuksynbio
February 4, 2025 at 6:56 AM
Moe Yabuta is now speaking about self-growing protocell models in aqueous two-phase system induced by internal DNA replication reaction. Beautiful talk by a PhD student... one to watch! #japanuksynbio
Patrick Cai now providing a tour de force on engineering and safeguarding synthetic genomes. So many exciting projects in his lab and to hear about how the field is progressing - look at all those big papers! 🤯 #japanuksynbio
February 4, 2025 at 6:24 AM
Patrick Cai now providing a tour de force on engineering and safeguarding synthetic genomes. So many exciting projects in his lab and to hear about how the field is progressing - look at all those big papers! 🤯 #japanuksynbio
Yuka Iwasaki now speaking on transcriptional silencing by small non-coding RNAs. Mind-blowing how many different types of small RNA exist. Yuka focusing on piRNAs with interesting functions in silencing transposable elements. #japanuksynbio
February 3, 2025 at 7:57 AM
Yuka Iwasaki now speaking on transcriptional silencing by small non-coding RNAs. Mind-blowing how many different types of small RNA exist. Yuka focusing on piRNAs with interesting functions in silencing transposable elements. #japanuksynbio
Hirohide Saito now speaking about RNA synthetic biology for mammalian cell programming. Some cool approaches to RNA evolution and generative design using AI! #japanuksynbio
February 3, 2025 at 7:23 AM
Hirohide Saito now speaking about RNA synthetic biology for mammalian cell programming. Some cool approaches to RNA evolution and generative design using AI! #japanuksynbio
While the science has been top notch at #japanuksynbio symposium... I've also fallen in love with the Japanese aesthetic of cute (and sometime crazy) cartoon characters everywhere! The western aesthetic is so clinical and dry, it's like a breath of fresh air 😍
February 3, 2025 at 7:11 AM
While the science has been top notch at #japanuksynbio symposium... I've also fallen in love with the Japanese aesthetic of cute (and sometime crazy) cartoon characters everywhere! The western aesthetic is so clinical and dry, it's like a breath of fresh air 😍
A shift now to the engineering of Acinetobacter sp. Tol 5 as a new cellular chassis for #synbio by Masahito Ishikawa. Excitig to see what new opportunities this will offer for the production of organic compounds and the application of it native adhesion to solid surfaces. #japanuksynbio
February 3, 2025 at 6:56 AM
A shift now to the engineering of Acinetobacter sp. Tol 5 as a new cellular chassis for #synbio by Masahito Ishikawa. Excitig to see what new opportunities this will offer for the production of organic compounds and the application of it native adhesion to solid surfaces. #japanuksynbio