Florian Plaza Oñate
fplazaonate.bsky.social
Florian Plaza Oñate
@fplazaonate.bsky.social
R&D Bioinformatician at @INRAE MetaGenoPolis
Reposted by Florian Plaza Oñate
🚨 New pre-print from the lab! We performed a large-scale meta-analysis of the uncultured gut #microbiome in >10,000 metagenomes enabling us to identify a new candidate biomarker of health. www.biorxiv.org/content/10.1...
Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a new candidate biomarker of health
The human gut microbiome plays an important biological role in host health, yet over 60% of gut species remain uncultured and hence inaccessible to experimental manipulation. Here we analysed 11,115 h...
www.biorxiv.org
September 10, 2025 at 11:44 AM
Reposted by Florian Plaza Oñate
Excited🚨to share our first work on the human gut phageome doi.org/10.1101/2025...
Always inspiring to work with @epcrocha.bsky.social , Erick D, Camille d'H and everyone else within this super dynamic consortium
@inrae-france.bsky.social+@pasteur.fr+@inserm.fr! Many thanks for this great journey!🙌
Third-generation cephalosporin antibiotics induce phage bursts in the human gut microbiome.
The use of antibiotics disrupts the gut microbiota, potentially leading to long-term health issues and the spread of resistance. To investigate the impact of antibiotics on phage populations, we follo...
doi.org
February 10, 2025 at 9:55 AM
Reposted by Florian Plaza Oñate
1/9 🚨 New preprint alert!

Frustrated by strange results with your metagenomic data?

Meet CroCoDeEL, an accurate, easy-to-use tool to detect and quantify cross-sample contamination—no need for negative controls or sample positions!

🔗 doi.org/10.1101/2025...
CroCoDeEL: accurate control-free detection of cross-sample contamination in metagenomic data
Metagenomic sequencing provides profound insights into microbial communities, but it is often compromised by technical biases, including cross-sample contamination. This underexplored phenomenon arise...
doi.org
January 20, 2025 at 12:42 PM