MP Foster Lab @ The Ohio State University
@fosterlab.bsky.social
Mark Foster lab in the Department of Chemistry and Biochemistry at The Ohio State University. We biophysical tools to study protein and nucleic acid structure, function, dynamics and interactions. https://go.osu.edu/fosterlab
Now out in #jbc doi.org/10.1016/j.jb... We use #nativeMS to simultaneously monitor ATP binding to multiple forms of open-ring Rho @biophysics-osu.bsky.social @gtresearch.bsky.social Great collaboration between the Wysocki and Foster groups
Redirecting
doi.org
November 12, 2025 at 10:12 PM
Now out in #jbc doi.org/10.1016/j.jb... We use #nativeMS to simultaneously monitor ATP binding to multiple forms of open-ring Rho @biophysics-osu.bsky.social @gtresearch.bsky.social Great collaboration between the Wysocki and Foster groups
Reposted by MP Foster Lab @ The Ohio State University
Kotaro received the 2025 Innovators in Healthcare and Life Sciences Award from Business First!
October 6, 2025 at 12:53 AM
Kotaro received the 2025 Innovators in Healthcare and Life Sciences Award from Business First!
The USDA has a message for you...
October 6, 2025 at 1:12 PM
The USDA has a message for you...
Reposted by MP Foster Lab @ The Ohio State University
Great Plains Regional Annual Symposium on Protein NMR & Integrated Structural Biology, October 17-18, Iowa State University, Ames, IA
Early-bird registration discount ends September 25
Best Oral Presentation & Travel Award Submission Deadline September 25
#NMRchat 🧲
Early-bird registration discount ends September 25
Best Oral Presentation & Travel Award Submission Deadline September 25
#NMRchat 🧲
2025 GRASP Great Plains Regional Annual Symposium on Protein and Biomolecular Nuclear Magnetic Resonance and Integrated Structural Biology, October 17-18, 2025 at Iowa State University in Ames, Iowa www.regcytes.extension.iastate.edu/grasp/ #NMRevents #NMRchat #NMR 🧲
Home - GRASP NMR
The 2025 GRASP NMR Symposium will be held October 17-18, 2025 at Iowa State University in Ames, Iowa. Our MissionThe GRASP symposium aims to highlight the pivotal role of protein NMR in integrated str...
www.regcytes.extension.iastate.edu
September 24, 2025 at 2:02 PM
Great Plains Regional Annual Symposium on Protein NMR & Integrated Structural Biology, October 17-18, Iowa State University, Ames, IA
Early-bird registration discount ends September 25
Best Oral Presentation & Travel Award Submission Deadline September 25
#NMRchat 🧲
Early-bird registration discount ends September 25
Best Oral Presentation & Travel Award Submission Deadline September 25
#NMRchat 🧲
Reposted by MP Foster Lab @ The Ohio State University
RT Héctor Busto @hebusto.bsky.social Resonancia Magnética Nuclear, herramienta contra el fraude. La Estación Enológica de Haro ha afianzado la técnica de control de calidad y de lucha contra el sabotaje de marca en el sector del vino #NMRchat 🧲🍷 @brukercorporation.bsky.social
Resonancia Magnética Nuclear, herramienta contra el fraude | La Rioja
La Estación Enológica de Haro ha afianzado la técnica de control de calidad y de lucha contra el sabotaje de marca en el sector del vino
larioja.com
September 2, 2025 at 6:58 PM
RT Héctor Busto @hebusto.bsky.social Resonancia Magnética Nuclear, herramienta contra el fraude. La Estación Enológica de Haro ha afianzado la técnica de control de calidad y de lucha contra el sabotaje de marca en el sector del vino #NMRchat 🧲🍷 @brukercorporation.bsky.social
Reposted by MP Foster Lab @ The Ohio State University
Team effort with @darjarohden.bsky.social 💪🏼👩🔬 targeting my second favourite amino acid by solid-state NMR. Many motion timescales accessible. And the next amino acid is already in the crosshairs (my third favourite 😏).
share.google/Q1ZzwJwDjjwA...
(yeah nothing beats tryptophan)
share.google/Q1ZzwJwDjjwA...
(yeah nothing beats tryptophan)
Arginine dynamics probed by magic-angle spinning NMR with a specific isotope-labeling scheme
The specific introduction of 1H-13C or 1H-15N moieties into otherwise deuterated proteins holds great potential for high-resolution solution and magic…
share.google
September 2, 2025 at 4:20 PM
Team effort with @darjarohden.bsky.social 💪🏼👩🔬 targeting my second favourite amino acid by solid-state NMR. Many motion timescales accessible. And the next amino acid is already in the crosshairs (my third favourite 😏).
share.google/Q1ZzwJwDjjwA...
(yeah nothing beats tryptophan)
share.google/Q1ZzwJwDjjwA...
(yeah nothing beats tryptophan)
Reposted by MP Foster Lab @ The Ohio State University
Journal of Molecular Biology (open) Review Article, Application of NMR to Large RNAs, Brian D. Grossman, Jan Marchant*, Michael F. Summers* www.sciencedirect.com/science/arti... #NMRchat 🧲
Application of NMR to Large RNAs
Heteronuclear NMR methodologies developed over the past 40 years have enabled atomic level insights into the solution-state structure and dynamics of …
www.sciencedirect.com
August 31, 2025 at 1:40 PM
Journal of Molecular Biology (open) Review Article, Application of NMR to Large RNAs, Brian D. Grossman, Jan Marchant*, Michael F. Summers* www.sciencedirect.com/science/arti... #NMRchat 🧲
Reposted by MP Foster Lab @ The Ohio State University
Wikipedia editors trying to fend off the onslaught of AI crap have crowdsourced some telltale signs of LLM-generated writing; it might be handy for editors and proofreaders generally. Thanks to @ellenrykers.com for pointing me to it. en.wikipedia.org/wiki/Wikiped...
Wikipedia:Signs of AI writing - Wikipedia
en.wikipedia.org
August 31, 2025 at 11:58 PM
Wikipedia editors trying to fend off the onslaught of AI crap have crowdsourced some telltale signs of LLM-generated writing; it might be handy for editors and proofreaders generally. Thanks to @ellenrykers.com for pointing me to it. en.wikipedia.org/wiki/Wikiped...
Reposted by MP Foster Lab @ The Ohio State University
NMRFx: Integrated Software for NMR Data Processing, Visualization, Analysis and Structure Calculation https://www.biorxiv.org/content/10.1101/2025.08.26.672401v1
August 29, 2025 at 11:46 PM
NMRFx: Integrated Software for NMR Data Processing, Visualization, Analysis and Structure Calculation https://www.biorxiv.org/content/10.1101/2025.08.26.672401v1
Reposted by MP Foster Lab @ The Ohio State University
I’m carrying out a short survey of NMR TITAN users - if you’ve made use of this tool in your research, or have suggestions for its future development, I’d be grateful for your input: forms.gle/MMXYwSozszhi... #nmrchat
NMR TITAN user survey
This survey aims to assess the impact of NMR TITAN on biomolecular research and identify priorities for future development. The form should take approximately 5 minutes to complete. Your responses may...
forms.gle
August 28, 2025 at 2:13 PM
I’m carrying out a short survey of NMR TITAN users - if you’ve made use of this tool in your research, or have suggestions for its future development, I’d be grateful for your input: forms.gle/MMXYwSozszhi... #nmrchat
Reposted by MP Foster Lab @ The Ohio State University
Get important feedback from your community and move your work forward. Share your research at #bps2026!
Submit an abstract today buff.ly/oOjstk6
Submit an abstract today buff.ly/oOjstk6
BPS2026 Annual Meeting | Biophysical Society
The BPS2026 Annual Meeting in San Francisco will showcase Biophysics by the Bay, highlighting the exciting advances in science and technology brought forth by big data and AI. This year’s program…
www.biophysics.org
August 27, 2025 at 12:01 PM
Get important feedback from your community and move your work forward. Share your research at #bps2026!
Submit an abstract today buff.ly/oOjstk6
Submit an abstract today buff.ly/oOjstk6
Reposted by MP Foster Lab @ The Ohio State University
How should scientists respond to groups that reject, reinterpret or claim scientific findings for their own political purposes?
Listen carefully: Teaching students to navigate science-scepticism
Science no longer enjoys unlimited and universal trust. An array of groups are questioning scientific wisdom. What does this mean for students and researchers? Gabriel Dorthe studies how trust and mis...
ethz.ch
August 19, 2025 at 7:33 AM
How should scientists respond to groups that reject, reinterpret or claim scientific findings for their own political purposes?
Reposted by MP Foster Lab @ The Ohio State University
Grace developed a virtual screening approach focused on cavities identified in the (NPSL2) RNA structure. She then validated screening "hits" experimentally.
Importantly, this approach is broadly applicable to any RNA with a known 3D structure.
Importantly, this approach is broadly applicable to any RNA with a known 3D structure.
Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin - Scientific Reports
Scientific Reports - Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin
www.nature.com
August 14, 2025 at 3:26 PM
Grace developed a virtual screening approach focused on cavities identified in the (NPSL2) RNA structure. She then validated screening "hits" experimentally.
Importantly, this approach is broadly applicable to any RNA with a known 3D structure.
Importantly, this approach is broadly applicable to any RNA with a known 3D structure.
Reposted by MP Foster Lab @ The Ohio State University
⏰Join us for the NMR Symposium, Nov 26–27, 2025, celebrating our new 1.2 GHz NMR spectrometer. To present a poster, send your abstract to NMR2025@fmp-berlin.de. Registrations are open until September 15th!
August 14, 2025 at 8:07 AM
⏰Join us for the NMR Symposium, Nov 26–27, 2025, celebrating our new 1.2 GHz NMR spectrometer. To present a poster, send your abstract to NMR2025@fmp-berlin.de. Registrations are open until September 15th!
Reposted by MP Foster Lab @ The Ohio State University
Sofia Lövestam's vault structure is now online in Structure @cellpress.bsky.social. 🥳
How beautifully explorative is #cryoEM! We never planned to do this. The vaults just came down with #amyloids from human brain tissue, and Sofia decided to have a closer look.
www.cell.com/structure/fu...
How beautifully explorative is #cryoEM! We never planned to do this. The vaults just came down with #amyloids from human brain tissue, and Sofia decided to have a closer look.
www.cell.com/structure/fu...
Cryo-EM structure of the vault from human brain reveals symmetry mismatch at its caps
Lövestam and Scheres present a cryo-EM structure of vault particles, found during
tau filament extraction from progressive supranuclear palsy (PSP) brain tissue. They
reveal a symmetry shift at the va...
www.cell.com
August 12, 2025 at 4:05 PM
Sofia Lövestam's vault structure is now online in Structure @cellpress.bsky.social. 🥳
How beautifully explorative is #cryoEM! We never planned to do this. The vaults just came down with #amyloids from human brain tissue, and Sofia decided to have a closer look.
www.cell.com/structure/fu...
How beautifully explorative is #cryoEM! We never planned to do this. The vaults just came down with #amyloids from human brain tissue, and Sofia decided to have a closer look.
www.cell.com/structure/fu...
Reposted by MP Foster Lab @ The Ohio State University
Last week's EO is in clear violation of federal law that gives Institute Directors e.g., the Director of NINDS or NIGMS etc, the final decision making authority in issuing grants of more than $50,000. The Institute Directors know this.
See b), 3), a)
www.law.cornell.edu/uscode/text/...
1/
See b), 3), a)
www.law.cornell.edu/uscode/text/...
1/
42 U.S. Code § 284 - Directors of national research institutes
www.law.cornell.edu
August 11, 2025 at 4:03 PM
Last week's EO is in clear violation of federal law that gives Institute Directors e.g., the Director of NINDS or NIGMS etc, the final decision making authority in issuing grants of more than $50,000. The Institute Directors know this.
See b), 3), a)
www.law.cornell.edu/uscode/text/...
1/
See b), 3), a)
www.law.cornell.edu/uscode/text/...
1/
Reposted by MP Foster Lab @ The Ohio State University
After receiving the sad news about the passing of Edwin Becker, I ran across his report in Analytical Chemistry titled "A Brief History of Nuclear Magnetic Resonance". It is a well-written piece that will entertain the magnetic resonance enthusiast. #chemsky #NMRsky pubs.acs.org/doi/abs/10.1...
A BRIEF HISTORY OF NUCLEAR MAGNETIC RESONANCE
pubs.acs.org
August 8, 2025 at 11:12 PM
After receiving the sad news about the passing of Edwin Becker, I ran across his report in Analytical Chemistry titled "A Brief History of Nuclear Magnetic Resonance". It is a well-written piece that will entertain the magnetic resonance enthusiast. #chemsky #NMRsky pubs.acs.org/doi/abs/10.1...
Reposted by MP Foster Lab @ The Ohio State University
Nature Communications (open) Seedless: on-the-fly pulse calculation for NMR experiments, Charles J. Buchanan, Gaurav Bhole, Gogulan Karunanithy, Virginia Casablancas-Antràs, Adeline W. J. Poh, Benjamin G. Davis, Jonathan A. Jones* & Andrew J. Baldwin* www.nature.com/articles/s41... #NMRchat #NMR 🧲
Seedless: on-the-fly pulse calculation for NMR experiments - Nature Communications
The authors develop a computational tool to design NMR pulses, based on the GRadient Assisted Pulse Engineering approach, that can calculate optimal pulse shapes on the fly during the measurements, to...
www.nature.com
August 8, 2025 at 2:03 PM
Nature Communications (open) Seedless: on-the-fly pulse calculation for NMR experiments, Charles J. Buchanan, Gaurav Bhole, Gogulan Karunanithy, Virginia Casablancas-Antràs, Adeline W. J. Poh, Benjamin G. Davis, Jonathan A. Jones* & Andrew J. Baldwin* www.nature.com/articles/s41... #NMRchat #NMR 🧲
Reposted by MP Foster Lab @ The Ohio State University
It’s difficult to overstate just how reckless and incompetent this is.
mRNA technology saved millions of lives during the COVID-19 crisis. Now, RFK Jr. is undermining the science that could protect us from the next pandemic—and putting American lives at risk.
mRNA technology saved millions of lives during the COVID-19 crisis. Now, RFK Jr. is undermining the science that could protect us from the next pandemic—and putting American lives at risk.
RFK Jr. pulls $500 million in funding for vaccine development
Twenty-two projects, totaling $500 million, to develop vaccines using mRNA technology will be halted, the health secretary announced. “I don’t think I’ve seen a more dangerous decision in public healt...
chicago.suntimes.com
August 7, 2025 at 5:38 PM
It’s difficult to overstate just how reckless and incompetent this is.
mRNA technology saved millions of lives during the COVID-19 crisis. Now, RFK Jr. is undermining the science that could protect us from the next pandemic—and putting American lives at risk.
mRNA technology saved millions of lives during the COVID-19 crisis. Now, RFK Jr. is undermining the science that could protect us from the next pandemic—and putting American lives at risk.
Negotiating with terrorists? This sure looks like a hostage situation.
It is not “deal-making.” It is extortion built on Christopher Rufo’s idea of “taking down” one or more elite university.
www.nytimes.com/2025/08/04/u...
www.nytimes.com/2025/08/04/u...
Trump’s Deal-Making With Other Elite Schools Scrambles Harvard Negotiations
www.nytimes.com
August 6, 2025 at 12:13 AM
Negotiating with terrorists? This sure looks like a hostage situation.
Reposted by MP Foster Lab @ The Ohio State University
Asking for help is not admitting failure, but rather using your resources to ensure that expectations are met. Knowing how to ask for help ensures that you get help that is actually useful, or even crucial, in meeting your goals. cen.acs.org/careers/care... #chemsky
How to get helpful help
Chemical & Engineering News (C&EN): Keeping you up to date with the chemistry news that matters most. Published by the American Chemical Society.
cen.acs.org
August 5, 2025 at 8:15 PM
Asking for help is not admitting failure, but rather using your resources to ensure that expectations are met. Knowing how to ask for help ensures that you get help that is actually useful, or even crucial, in meeting your goals. cen.acs.org/careers/care... #chemsky
Reposted by MP Foster Lab @ The Ohio State University
🍺 Homebrew 4.6.0 is out!
Opt-in concurrent downloads (`HOMEBREW_DOWNLOAD_CONCURRENCY`), early macOS 26 (Tahoe) support, a built-in `brew mcp-server` and lots of other fixes.
Run `brew update` to get it.
Full details at: brew.sh/2025/08/05/h...
Opt-in concurrent downloads (`HOMEBREW_DOWNLOAD_CONCURRENCY`), early macOS 26 (Tahoe) support, a built-in `brew mcp-server` and lots of other fixes.
Run `brew update` to get it.
Full details at: brew.sh/2025/08/05/h...
4.6.0
Today, I’d like to announce Homebrew 4.6.0. The most significant changes since 4.5.0 are opt-in concurrent downloads with HOMEBREW_DOWNLOAD_CONCURRENCY, preliminary macOS 26 (Tahoe) support and a buil...
brew.sh
August 5, 2025 at 10:24 AM
🍺 Homebrew 4.6.0 is out!
Opt-in concurrent downloads (`HOMEBREW_DOWNLOAD_CONCURRENCY`), early macOS 26 (Tahoe) support, a built-in `brew mcp-server` and lots of other fixes.
Run `brew update` to get it.
Full details at: brew.sh/2025/08/05/h...
Opt-in concurrent downloads (`HOMEBREW_DOWNLOAD_CONCURRENCY`), early macOS 26 (Tahoe) support, a built-in `brew mcp-server` and lots of other fixes.
Run `brew update` to get it.
Full details at: brew.sh/2025/08/05/h...
Reposted by MP Foster Lab @ The Ohio State University
Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR, Ben P. Tatman*, Vidhyalakshmi Sridharan, Motilal Uttarkabat, Christopher P. Jaroniec, Matthias Ernst, Petra Rovó, Paul Schanda* pubs.acs.org/doi/10.1021/... #NMRchat 🧲
Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR
Microsecond-to-millisecond motions are instrumental for many biomolecular functions, including enzymatic activity and ligand binding. Bloch-McConnell Relaxation Dispersion (BMRD) Nuclear Magnetic Reso...
pubs.acs.org
August 2, 2025 at 4:20 PM
Bumps on the Road: The Way to Clean Relaxation Dispersion Magic-Angle Spinning NMR, Ben P. Tatman*, Vidhyalakshmi Sridharan, Motilal Uttarkabat, Christopher P. Jaroniec, Matthias Ernst, Petra Rovó, Paul Schanda* pubs.acs.org/doi/10.1021/... #NMRchat 🧲
Reposted by MP Foster Lab @ The Ohio State University
@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky 🧪
Jennifer Doudna is named 2026 Priestley Medalist
The award recognizes the biochemist for discoveries on ribozyme function and CRISPR gene editing, and international science leadership
cen.acs.org
August 2, 2025 at 4:08 PM
@acs.org is recognizing Jennifer A. Doudna with the Priestley Medal for her discoveries on ribozyme function, the Dicer RNase enzyme, double-stranded RNA processing, and CRISPR gene editing, along with her impactful international science leadership. cen.acs.org/people/award... #chemsky 🧪
Reposted by MP Foster Lab @ The Ohio State University
The 64th Annual Rocky Mountain Conference on Magnetic Resonance (RMCMR) EPR Symposium will take place August 3-7, 2025 at the Snowbird Resort & Conference Center, Snowbird, Utah rockychem.com #NMRchat #NMR #NMRevents #ESR #EPR 🧲
December 20, 2024 at 5:37 PM
The 64th Annual Rocky Mountain Conference on Magnetic Resonance (RMCMR) EPR Symposium will take place August 3-7, 2025 at the Snowbird Resort & Conference Center, Snowbird, Utah rockychem.com #NMRchat #NMR #NMRevents #ESR #EPR 🧲