γδ T cell Forum
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γδ T cell Forum
@forum-gd.bsky.social
Forum for basic and clinical researchers interested in the biology of gamma/delta T cells and their role in the immune system.
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#gdTcells
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γ9δ2 T cells detect mevalonate diphosphate via BTN3A3

#gdTcells
γ9δ2 T cells detect mevalonate diphosphate via BTN3A3.
www.lifescience.net
November 15, 2025 at 8:41 AM
Found it! 😉

👇
November 15, 2025 at 8:37 AM
For all #GDTcellclub enthusiasts, you'll have to wait a little longer for your next installment - our November webinar has been re-scheduled to December 4th (12pm EST). We promise will be worth the wait!
October 21, 2025 at 12:45 PM
Reposted by γδ T cell Forum
PhD opportunity to study intestinal immune cells using our pioneer human organoid models at the Joana F Neves and Robin Dart labs @kingscollegelondon.bsky.social through #MRC Doutoral training program
kcl-mrcdtp.com/project/deco...
Applications opening soon!
#gdTcells #IBD #gut #organoids
Decoding γδ T cell-epithelial interactions in the human intestine in health and disease - MRC DTP
The human gut epithelium performs vital absorptive functions, while simultaneously forming a physical barrier between the gut contents and the body. As such it is essential for health and its dysregul...
kcl-mrcdtp.com
October 7, 2025 at 8:13 AM
Thank you to Drs. Wei Weng and Yue Xing for their fantastic talks today and to the live attendees for joining us today for the #GDTcellclub October 2025 seminars. Here's a link with Dr. Wei Weng's recording from today's talk.

nyulangone.zoom.us/rec/share/Zz...
Passcode: S#$rbX0#
October 16, 2025 at 6:00 PM
Join us know for two exciting talks on brand new gd biology, we are in for a treat!

Note: only the talk from Dr Wei Weng will be recorded, you must tune in live to hear from Dr Yue Xing.
Join us on Thursday - October 16 at 12pm (EDT) for our #GDTcellclub webinars with Drs. Wei Weng (ingenious gene targeting) and Yue Xing (Mount Sinai School of Medicine).

Join Zoom Meeting:

nyulangone.zoom.us/j/9589051706...

Meeting ID: 958 9051 7066
Password: 369081
October 16, 2025 at 4:04 PM
Join us on Thursday - October 16 at 12pm (EDT) for our #GDTcellclub webinars with Drs. Wei Weng (ingenious gene targeting) and Yue Xing (Mount Sinai School of Medicine).

Join Zoom Meeting:

nyulangone.zoom.us/j/9589051706...

Meeting ID: 958 9051 7066
Password: 369081
October 11, 2025 at 3:21 PM
BTN2A1 acquisition through trogocytosis enhances Vγ9Vδ2 T cell cytotoxicity against autologous and cancer cells

#gdTcells @cp-cellreports.bsky.social
BTN2A1 acquisition through trogocytosis enhances Vγ9Vδ2 T cell cytotoxicity against autologous and cancer cells
Billon et al. show that CD3/CD28 stimulation induces BTN2A1 protein expression in immune cells via cell-to-cell contact with myeloid cells, through trogocytosis. This transfer makes lymphocytes more s...
www.cell.com
October 10, 2025 at 4:03 PM
IL-17-producing γδ T cells in the tumor microenvironment promote radioresistance in mice

#gdTcells @jci.org
JCI - IL-17-producing γδ T cells in the tumor microenvironment promote radioresistance in mice
www.jci.org
October 8, 2025 at 10:17 AM
Antibody-like recognition of a γδ T cell receptor toward a foreign antigen

#gdTcells
Antibody-like recognition of a γδ T cell receptor toward a foreign antigen
Rashleigh et al. utilized phycoerythrin, a bacterial derived protein, to explore immune reactivity of B cells, αβ T cells, and γδ T cells. All lymphocytes directly recognized PE, while T cell recognit...
www.cell.com
October 5, 2025 at 3:17 PM
Microbial metabolic pathways guide response to immune checkpoint blockade therapy

#gdTcells
Microbial metabolic pathways guide response to immune checkpoint blockade therapy
Abstract. Studies have identified a link between specific microbiome-derived bacteria and immune checkpoint blockade (ICB) efficacy. However, these species lack consistency across studies and their im...
doi.org
September 26, 2025 at 10:40 AM
Reposted by γδ T cell Forum
👀 We're on the lookout for a talented immunologist to join us for a postdoc at Mount Sinai! If you are a recent PhD graduate, love spectral flow and want to join our γδ T cell crew, apply below! Livable wage + subsidized housing + Central Park. Help us spread the word! #gdTcells #Immunosky #GISky
Post Doctoral Fellow-MSH-20093-003 in New York, NY | Mount Sinai Health Systems
Mount Sinai is hiring a Post Doctoral Fellow-MSH-20093-003 in New York, NY. Review all of the job details and apply today!
careers.mountsinai.org
August 28, 2025 at 6:45 PM
Reposted by γδ T cell Forum
our study on #gdTcells in pediatric neuroblastoma is out! In contrast to adult tumors, it is the gdTcells that not only expand, but that are the most tumor reactive #TILs.

#immunology #tumorimmunology

funded by KIKA, Sanquin and supported by Oncode

www.life-science-alliance.org/content/8/11...
γδ T cells are the prime antitumoral T cells in pediatric neuroblastoma
High-risk pediatric neuroblastoma patients have a dismal survival rate despite intensive treatment regimens. New treatment options are thus required. Even though HLA expression in neuroblastoma is low...
www.life-science-alliance.org
September 3, 2025 at 6:53 AM
Reposted by γδ T cell Forum
check out our new commentary on 2 recently published papers about #gdTcells in breast cancer
www.sciencedirect.com/science/arti...
γδT cells and breast cancer: wicked allies
Metastatic disease and therapy resistance pose significant challenges in the treatment of breast cancer. Recent studies by Rozalén et al. and Petroni …
www.sciencedirect.com
September 9, 2025 at 6:44 AM
Reposted by γδ T cell Forum
"Microbe-responsive human γδ T cells: The peculiar case of Staphylococcus aureus"

To Armin and Martin. 🕯️

#gdTcells
<em>Immunology & Cell Biology</em> | ASI Journal | Wiley Online Library
Human Vγ9/Vδ2 T cells display a unique responsiveness towards microbial organisms producing the metabolite HMB-PP. However, Staphylococcus aureus does not possess HMB-PP but can induce activation, cy...
onlinelibrary.wiley.com
September 23, 2025 at 7:26 AM
Reposted by γδ T cell Forum
📚 NEW #gdT-cell PAPER from our team @QMUL.bsky.social! 🥳 'Bacterial suppression of intestinal fungi via activation of human gut γδ T-cells' out now on @biorxiv-immuno
www.biorxiv.org/content/10.1... Here's my first attempt at a 'Bluetorial'... 🧵 1/10 #gastrosky #IBDsky
Bacterial suppression of intestinal fungi via activation of human gut γδ T-cells
Gut symbionts condition mucosal immunity to resist infection by enteropathogens, but the specific microbes and mechanisms involved differ significantly between host species. In higher primates, bacter...
www.biorxiv.org
September 21, 2025 at 6:58 PM
If you missed today's seminars by Drs. Inacio and Gonzalez, please see the recorded sessions here:

nyulangone.zoom.us/rec/share/Ai...
Passcode: GDTcellclub_Sept2025
September 18, 2025 at 9:43 PM
Our next speaker is Dr Octavio Gonzalez, sharing his work on the impact of aging on gingival gd T cells.
September 18, 2025 at 4:35 PM
Join us now to hear from Dr Daniel Inácio about the molecular control of gd T cell subset differentiation and effector function.
September 18, 2025 at 4:07 PM
Starting up with Dr. Daniel P. Inacio from Univ. of Lisbon about effector functions of #GDTcells.. join us!
September 18, 2025 at 4:06 PM
Reposted by γδ T cell Forum
Please join us for the upcoming September #GDTcellclub Virtual talks by Drs. Daniel P. Inacio and Octavio A. Gonzalez on Sept 18 at 12pm NY/5pm Lisbon

Bookmark for up-to-date announcements 👇
payalyokota.com/gamma-delta-...

Zoom: nyulangone.zoom.us/j/9589051706...

@forum-gd.bsky.social
September 18, 2025 at 2:53 AM
Join us tomorrow for our next #GDTcellclub webinar, where we are delighted to host Drs Octavio Gonzalez and Daniel Inácio.

Date: September 18, 2025
Time: 12pm (New York) | 5pm (London, UK)

nyulangone.zoom.us/j/9589051706...

*Talks will be recorded* for those who are unable to attend live.
September 17, 2025 at 12:56 PM
TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming

#gdTcells @jem.org
TLR2 supports γδ T cell IL-17A response to ocular surface commensals by metabolic reprogramming
Ocular commensal C. mast induces IL-17 responses from Vγ6 T cells, helping to maintain mucosal barrier function of the conjunctiva. Mechanistically, Vγ6 T
rupress.org
September 16, 2025 at 12:44 PM
Cytotoxic CX3CR1+ Vδ1 T cells clonally expand in an interplay of CMV, microbiota, and HIV-1 persistence in people on antiretroviral therapy

#gdTcells
Cytotoxic CX3CR1+ Vδ1 T cells clonally expand in an interplay of CMV, microbiota, and HIV-1 persistence in people on antiretroviral therapy
Author summary Vδ1 T cells are key immune cells, particularly in the intestinal mucosa, which is a major site of HIV-1 persistence during antiretroviral therapy. Disruption of the gut microenvironment...
journals.plos.org
September 9, 2025 at 11:09 AM