left: inner ear; center: transverse section of the cochlear duct; right: section showing the cochlear duct spiraling around the modiolus/spiral ganglion
October 31, 2025 at 11:17 PM
left: inner ear; center: transverse section of the cochlear duct; right: section showing the cochlear duct spiraling around the modiolus/spiral ganglion
This is just the beginning of this line of research. And other teams have developed different approaches to unravel the mechanisms of cochlear amplification. The field is moving fast! Definitely an exciting time for research on cochlear mechanics.
June 16, 2025 at 10:47 AM
This is just the beginning of this line of research. And other teams have developed different approaches to unravel the mechanisms of cochlear amplification. The field is moving fast! Definitely an exciting time for research on cochlear mechanics.
This could however explain several observations, including the orientation of collagen fibers in the tectorial membrane (stained in blue in the picture below), which conveys the velocity gradient in this hypothesis. bsky.app/profile/audi...
We've been sifting through our archive of 1960s histology sections. Here, the organ of Corti (auditory sensory epithelium of the cochlea) is viewed using Mallory's trichrome stain. The outer hair cells (centre right) are stained orange. 🔬🧪👂 #neuroskyence
June 16, 2025 at 10:47 AM
This could however explain several observations, including the orientation of collagen fibers in the tectorial membrane (stained in blue in the picture below), which conveys the velocity gradient in this hypothesis. bsky.app/profile/audi...
We did some simulations based on this idea, leading to some control on the traveling wave peak (below: variable viscous load). But this mechanism alone could not explain the whole range of amplification/compression that we see in experimental data.
June 16, 2025 at 10:47 AM
We did some simulations based on this idea, leading to some control on the traveling wave peak (below: variable viscous load). But this mechanism alone could not explain the whole range of amplification/compression that we see in experimental data.
We hypothesized that this ‘gradient’ of velocity could control deformations in the tectorial membrane, modulating viscoelastic loss and giving rise to a mechanism of undamping.
June 16, 2025 at 10:47 AM
We hypothesized that this ‘gradient’ of velocity could control deformations in the tectorial membrane, modulating viscoelastic loss and giving rise to a mechanism of undamping.
Our proposal stems from recent observation that the three rows of outer hair cells don’t move with the same magnitude. The outer rows show greater motion compared to the most inner row.
June 16, 2025 at 10:40 AM
Our proposal stems from recent observation that the three rows of outer hair cells don’t move with the same magnitude. The outer rows show greater motion compared to the most inner row.