Using scRNA sequencing of all ventricular progenitors, we found genes with spatially and temporally restricted expression (baumannn.shinyapps.io/Ventriculome). Amongst these, the mitochondrial protein Fam210b was expressed where and when cell-cycle is the longest.

As a first step to address this question, we built a spatio-temporal atlas of neuronal birth across brain structures, available at neurobirth.org (use your PC to navigate), building on Altman and Bayer’s seminal work on brain development (www.neurondevelopment.org).