Elleke Tissink
@eptissink.bsky.social
Researcher at University of Oslo
Likes to be where population neuroimaging and psychiatric genetics meet
Likes to be where population neuroimaging and psychiatric genetics meet
Reposted by Elleke Tissink
Have a look at this new honours course coordinated and taught by many GENE Amsterdam researchers in Amsterdam🧬: vu.nl/en/education...
Sem02 (2025-2026) From Genetics to Gen-Ethics - Vrije Universiteit Amsterdam
Explore how advances in genetic research intersect with questions of social impact and responsibility and examine the promises and challenges of genetics.
vu.nl
November 20, 2025 at 9:31 AM
Have a look at this new honours course coordinated and taught by many GENE Amsterdam researchers in Amsterdam🧬: vu.nl/en/education...
Reposted by Elleke Tissink
First time on Bsky and first big announcement!
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
Estimation and mapping of the missing heritability of human phenotypes - Nature
WGS data were used from 347,630 individuals with European ancestry in the UK Biobank to obtain high-precision estimates of coding and non-coding rare variant heritability for 34 co...
www.nature.com
November 12, 2025 at 5:57 PM
First time on Bsky and first big announcement!
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
Reposted by Elleke Tissink
Two birds of a gene - catch Matt Keller's webinar at @uio.no on October 15th. Please share
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
Using structural equation models to estimate direct and indirect genetic effects and assortative mating in trio data
- PROMENTA
Guest lecture by Matt Keller
www.sv.uio.no
October 5, 2025 at 11:11 AM
Two birds of a gene - catch Matt Keller's webinar at @uio.no on October 15th. Please share
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
Reposted by Elleke Tissink
Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
FEMA-Long: Modeling unstructured covariances for discovery of time-dependent effects in large-scale longitudinal datasets
Linear mixed-effects (LME) models are commonly used for analyzing longitudinal data. However, most applications of LME models rely on random intercepts or simple, e.g., stationary, covariance. Here, w...
www.biorxiv.org
May 16, 2025 at 3:22 PM
Introducing FEMA-Long for high-dimensional large-scale mixed-effects modelling! Includes modelling unstructured covariance, non-linear effects using splines, time-dependent effects with spline interactions, and longitudinal GWAS with time-dependent genetic effects!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
My first postdoc was all about exploring the intertwined nature of insomnia, anxiety, and depression. Looking at this through the neuroimaging lens, @siemon.bsky.social published this huge effort in Nature Mental Health today 🧠 Stay tuned for the genetics counterpart... 🧬
💡 New publication on insomnia, anxiety, and depression. 🧠
Large-scale brain imaging study reveals shared and distinct neural features, pointing to a common brain circuit underlying these disorders.
@siemon.bsky.social @eptissink.bsky.social
Read the article here 👇
www.nature.com/articles/s44...
Large-scale brain imaging study reveals shared and distinct neural features, pointing to a common brain circuit underlying these disorders.
@siemon.bsky.social @eptissink.bsky.social
Read the article here 👇
www.nature.com/articles/s44...
Multimodal brain imaging of insomnia, depression and anxiety symptoms indicates transdiagnostic commonalities and differences - Nature Mental Health
The authors used data from the UK Biobank to identify associations of self-rated symptoms of insomnia, depression and anxiety with cortical area, cortical thickness, subcortical volume, structural con...
www.nature.com
May 2, 2025 at 10:21 AM
My first postdoc was all about exploring the intertwined nature of insomnia, anxiety, and depression. Looking at this through the neuroimaging lens, @siemon.bsky.social published this huge effort in Nature Mental Health today 🧠 Stay tuned for the genetics counterpart... 🧬
Reposted by Elleke Tissink
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications
Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.
www.nature.com
March 26, 2025 at 1:54 AM
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
Reposted by Elleke Tissink
New preprint! 🗞️
Lucy Whitmore and I discuss the many potential challenges in using the brain age prediction framework in children and adolescents, and make recommendations for future directions.
🔗: osf.io/preprints/ps...
Lucy Whitmore and I discuss the many potential challenges in using the brain age prediction framework in children and adolescents, and make recommendations for future directions.
🔗: osf.io/preprints/ps...
March 14, 2025 at 9:28 AM
New preprint! 🗞️
Lucy Whitmore and I discuss the many potential challenges in using the brain age prediction framework in children and adolescents, and make recommendations for future directions.
🔗: osf.io/preprints/ps...
Lucy Whitmore and I discuss the many potential challenges in using the brain age prediction framework in children and adolescents, and make recommendations for future directions.
🔗: osf.io/preprints/ps...
Reposted by Elleke Tissink
Incredibly proud to see our latest work out in Nature Genetics: www.nature.com/articles/s41...
Here we share our FLAMES framework, which predicts the effector genes in GWAS loci with state-of-the-art precision🔥
Special thanks to @daniposthu.bsky.social
A full thread describing findings below!
Here we share our FLAMES framework, which predicts the effector genes in GWAS loci with state-of-the-art precision🔥
Special thanks to @daniposthu.bsky.social
A full thread describing findings below!
Prioritizing effector genes at trait-associated loci using multimodal evidence
Nature Genetics - FLAMES is a machine learning approach combining variant fine-mapping, SNP-to-gene annotations and convergence-based gene prioritization scores to identify candidate effector genes...
rdcu.be
February 11, 2025 at 9:58 AM
Incredibly proud to see our latest work out in Nature Genetics: www.nature.com/articles/s41...
Here we share our FLAMES framework, which predicts the effector genes in GWAS loci with state-of-the-art precision🔥
Special thanks to @daniposthu.bsky.social
A full thread describing findings below!
Here we share our FLAMES framework, which predicts the effector genes in GWAS loci with state-of-the-art precision🔥
Special thanks to @daniposthu.bsky.social
A full thread describing findings below!
Reposted by Elleke Tissink
The ENIGMA-EEG working group of the ENIGMA consortium is looking for a PhD candidate to investigate the development and genetics of electrophysiological brain activity. Read all about it (and apply) here: werkenbij.amsterdamumc.org/en/vacatures...
werkenbij.amsterdamumc.org
February 11, 2025 at 10:28 AM
The ENIGMA-EEG working group of the ENIGMA consortium is looking for a PhD candidate to investigate the development and genetics of electrophysiological brain activity. Read all about it (and apply) here: werkenbij.amsterdamumc.org/en/vacatures...
Reposted by Elleke Tissink
𝐎𝐏𝐄𝐍 𝐂𝐀𝐋𝐋
We are excited to launch NeuroNarratives, an art-science residency bringing neuroscientists and artists together to create meaningful art based on science!
Sign up via de link in bio!
#opencall #artandscience #art #science #artscienceresidency #neuroscience
We are excited to launch NeuroNarratives, an art-science residency bringing neuroscientists and artists together to create meaningful art based on science!
Sign up via de link in bio!
#opencall #artandscience #art #science #artscienceresidency #neuroscience
January 27, 2025 at 3:07 PM
𝐎𝐏𝐄𝐍 𝐂𝐀𝐋𝐋
We are excited to launch NeuroNarratives, an art-science residency bringing neuroscientists and artists together to create meaningful art based on science!
Sign up via de link in bio!
#opencall #artandscience #art #science #artscienceresidency #neuroscience
We are excited to launch NeuroNarratives, an art-science residency bringing neuroscientists and artists together to create meaningful art based on science!
Sign up via de link in bio!
#opencall #artandscience #art #science #artscienceresidency #neuroscience