Emil Laust Kristoffersen, PhD
@emillk.bsky.social
Assistant professor at the Interdisciplinary Nanoscience Center, Aarhus University in Denmark and genetically related to the origin of life.
I study functional nucleic acids focusing on their role in starting evolution.
I study functional nucleic acids focusing on their role in starting evolution.
🌍
Today is is early deadline for registering for the first Danish Origins of Life Symposium in Copenhagen, which we are organizing.
projects.au.dk/doli/danish-...
Sign up now if you want to be in the run for presenting at the meeting. Registration will remain open for poster presentations.
🪐
Today is is early deadline for registering for the first Danish Origins of Life Symposium in Copenhagen, which we are organizing.
projects.au.dk/doli/danish-...
Sign up now if you want to be in the run for presenting at the meeting. Registration will remain open for poster presentations.
🪐
June 20, 2025 at 6:37 AM
🌍
Today is is early deadline for registering for the first Danish Origins of Life Symposium in Copenhagen, which we are organizing.
projects.au.dk/doli/danish-...
Sign up now if you want to be in the run for presenting at the meeting. Registration will remain open for poster presentations.
🪐
Today is is early deadline for registering for the first Danish Origins of Life Symposium in Copenhagen, which we are organizing.
projects.au.dk/doli/danish-...
Sign up now if you want to be in the run for presenting at the meeting. Registration will remain open for poster presentations.
🪐
The main structure, a dimer, inhibits RCS but can be reactivated making way for potential double RCS.
Overall, the paper emphasizes the importance of template structure for self-replication and offers new insights into how the initial replication machinery might have looked and functioned.
(3/4)
Overall, the paper emphasizes the importance of template structure for self-replication and offers new insights into how the initial replication machinery might have looked and functioned.
(3/4)
June 18, 2025 at 9:42 AM
The main structure, a dimer, inhibits RCS but can be reactivated making way for potential double RCS.
Overall, the paper emphasizes the importance of template structure for self-replication and offers new insights into how the initial replication machinery might have looked and functioned.
(3/4)
Overall, the paper emphasizes the importance of template structure for self-replication and offers new insights into how the initial replication machinery might have looked and functioned.
(3/4)
In the paper, we investigate RNA polymerase ribozymes and their ability to perform rolling circle synthesis (RCS).
We previously showed that RCS is possible, though inefficient. Now, we use cryo-EM and identify a network of unexpected structures (see movie) which affect RCS.
(2/4)
We previously showed that RCS is possible, though inefficient. Now, we use cryo-EM and identify a network of unexpected structures (see movie) which affect RCS.
(2/4)
June 18, 2025 at 9:41 AM
In the paper, we investigate RNA polymerase ribozymes and their ability to perform rolling circle synthesis (RCS).
We previously showed that RCS is possible, though inefficient. Now, we use cryo-EM and identify a network of unexpected structures (see movie) which affect RCS.
(2/4)
We previously showed that RCS is possible, though inefficient. Now, we use cryo-EM and identify a network of unexpected structures (see movie) which affect RCS.
(2/4)
Just received this super cool comic book on the origins of life in the RNA world! Great work! ❤️
June 3, 2025 at 7:55 AM
Just received this super cool comic book on the origins of life in the RNA world! Great work! ❤️
🪐 🧬 🦠
Very excited to announce our Origins of Life Seminar in the summer of 2025 at the Royal Danish Academy of Sciences and Letters!!!
The meeting will focus on bridging the distances in which life works - from light years to nanometers. 📐
Checkout our great speaker-list and stay tuned for more!
Very excited to announce our Origins of Life Seminar in the summer of 2025 at the Royal Danish Academy of Sciences and Letters!!!
The meeting will focus on bridging the distances in which life works - from light years to nanometers. 📐
Checkout our great speaker-list and stay tuned for more!
April 29, 2025 at 11:04 AM
🪐 🧬 🦠
Very excited to announce our Origins of Life Seminar in the summer of 2025 at the Royal Danish Academy of Sciences and Letters!!!
The meeting will focus on bridging the distances in which life works - from light years to nanometers. 📐
Checkout our great speaker-list and stay tuned for more!
Very excited to announce our Origins of Life Seminar in the summer of 2025 at the Royal Danish Academy of Sciences and Letters!!!
The meeting will focus on bridging the distances in which life works - from light years to nanometers. 📐
Checkout our great speaker-list and stay tuned for more!
Very interesting program at the Cryo-EM: next 50 years symposium at Berkely. Solving more RNA structures is on the todo!
January 12, 2025 at 2:55 PM
Very interesting program at the Cryo-EM: next 50 years symposium at Berkely. Solving more RNA structures is on the todo!
Looking at the 2D structure of the heterodimeric triplet polymerase ribozyme (TPR), always reminds me of the bronze-age petroglyphs of the plow driven by oxes 😅
Cool example that evolution likes cooperativity.
See the full paper: www.pnas.org/doi/10.1073/...
Cool example that evolution likes cooperativity.
See the full paper: www.pnas.org/doi/10.1073/...
December 7, 2024 at 1:38 PM
Looking at the 2D structure of the heterodimeric triplet polymerase ribozyme (TPR), always reminds me of the bronze-age petroglyphs of the plow driven by oxes 😅
Cool example that evolution likes cooperativity.
See the full paper: www.pnas.org/doi/10.1073/...
Cool example that evolution likes cooperativity.
See the full paper: www.pnas.org/doi/10.1073/...