emedei70.bsky.social
@emedei70.bsky.social
Reposted
#WeekendRead. #EveryOrganIsAnImmuneOrgan. Medei &co show @naturecvr.bsky.social that IL1b initiates a positive feedback loop leading to IL1b production by, & response of, cardiac resident macrophages which drives atrial fibrillation. Targeting resident macrophages is protective.
#ScienceSavesLives
IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expression - Nature Cardiovascular Research
Moreno-Loaiza et al. found that interleukin-1β, acting upon cardiac resident macrophages, promotes atrial fibrillation in mice, and this mechanism may represent a common pathway connecting various ris...
www.nature.com
February 9, 2025 at 5:56 PM
Reposted
We need better ways to prevent atrial fibrillation, a major risk factor for stroke. A new study demonstrates the importance of an inflammatory mediator (interleukin-1β) that can be blocked. Results from an experimental model but worthy of clinical assesement
www.nature.com/articles/s44...
IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expression - Nature Cardiovascular Research
Moreno-Loaiza et al. found that interleukin-1β, acting upon cardiac resident macrophages, promotes atrial fibrillation in mice, and this mechanism may represent a common pathway connecting various ris...
www.nature.com
February 6, 2025 at 2:54 PM
Very happy with our publication in @naturecvr.bsky.social
February 6, 2025 at 4:40 PM