Emmanuel Levy's lab
@elevylab.bsky.social
Structural & Systems Biology Lab @ University of Geneva | Exploring protein & proteome assemblies | Structured thoughts, intrinsically disordered views
Reposted by Emmanuel Levy's lab
Hot off the press! Our paper, “Global comparative structural analysis of responses to protein phosphorylation”, is now out in Nature Communications!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Global comparative structural analysis of responses to protein phosphorylation - Nature Communications
Phosphorylation is central to protein regulation, yet its structural mechanisms remain poorly understood. Here, the authors conduct a global, systematic analysis of phosphorylated versus non-phosphory...
www.nature.com
October 27, 2025 at 10:29 AM
Hot off the press! Our paper, “Global comparative structural analysis of responses to protein phosphorylation”, is now out in Nature Communications!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Molecular Armor: Simple Rules to Keep Proteins (Re)Soluble💧
Check our preview of a cool study on how proteins stay soluble (or not) after desiccation—from the labs of S. Fried, @alexholehouse.bsky.social and @shaharsu.bsky.social in @cp-cellsystems.bsky.social
www.sciencedirect.com/science/arti...
Check our preview of a cool study on how proteins stay soluble (or not) after desiccation—from the labs of S. Fried, @alexholehouse.bsky.social and @shaharsu.bsky.social in @cp-cellsystems.bsky.social
www.sciencedirect.com/science/arti...
October 16, 2025 at 8:46 AM
Molecular Armor: Simple Rules to Keep Proteins (Re)Soluble💧
Check our preview of a cool study on how proteins stay soluble (or not) after desiccation—from the labs of S. Fried, @alexholehouse.bsky.social and @shaharsu.bsky.social in @cp-cellsystems.bsky.social
www.sciencedirect.com/science/arti...
Check our preview of a cool study on how proteins stay soluble (or not) after desiccation—from the labs of S. Fried, @alexholehouse.bsky.social and @shaharsu.bsky.social in @cp-cellsystems.bsky.social
www.sciencedirect.com/science/arti...
Reposted by Emmanuel Levy's lab
Tenure-track Assistant Professorship in #Quantitative #Cell #Biology at the ICB @unibern. Apply until 17 October. Combination of theory/computation and experiments particularly encouraged. Please repost!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
September 30, 2025 at 5:58 AM
Tenure-track Assistant Professorship in #Quantitative #Cell #Biology at the ICB @unibern. Apply until 17 October. Combination of theory/computation and experiments particularly encouraged. Please repost!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by Emmanuel Levy's lab
Be our new colleague! 🎉
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.
👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch
Please feel free to share this opportunity with your network.
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.
👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch
Please feel free to share this opportunity with your network.
September 15, 2025 at 2:33 PM
Be our new colleague! 🎉
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.
👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch
Please feel free to share this opportunity with your network.
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.
👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch
Please feel free to share this opportunity with your network.
Reposted by Emmanuel Levy's lab
10/2025 Issue ➡️ www.embopress.org/toc/17444292...
reduced genomes, adaptive mutations under stress, xenobiotics and gut microbiome, DMS analysis, TF effector metabolites
Cover: proteins can agglomerate with limited impact on cell by @elevylab.bsky.social
reduced genomes, adaptive mutations under stress, xenobiotics and gut microbiome, DMS analysis, TF effector metabolites
Cover: proteins can agglomerate with limited impact on cell by @elevylab.bsky.social
October 7, 2025 at 6:16 PM
10/2025 Issue ➡️ www.embopress.org/toc/17444292...
reduced genomes, adaptive mutations under stress, xenobiotics and gut microbiome, DMS analysis, TF effector metabolites
Cover: proteins can agglomerate with limited impact on cell by @elevylab.bsky.social
reduced genomes, adaptive mutations under stress, xenobiotics and gut microbiome, DMS analysis, TF effector metabolites
Cover: proteins can agglomerate with limited impact on cell by @elevylab.bsky.social
@molsystbiol.org picked a neat cover for this month's issue 🙃 - Great work from Tal Levin, Hector Garcia-Seisdedos, many more colleagues (doi.org/10.1038/s443...) and great matching cover, too!
October 5, 2025 at 7:40 PM
@molsystbiol.org picked a neat cover for this month's issue 🙃 - Great work from Tal Levin, Hector Garcia-Seisdedos, many more colleagues (doi.org/10.1038/s443...) and great matching cover, too!
Reposted by Emmanuel Levy's lab
MMseqs2-GPU sets new standards in single query search speed, allows near instant search of big databases, scales to multiple GPUs and is fast beyond VRAM. It enables ColabFold MSA generation in seconds and sub-second Foldseek search against AFDB50. 1/n
📄 www.nature.com/articles/s41...
💿 mmseqs.com
📄 www.nature.com/articles/s41...
💿 mmseqs.com
GPU-accelerated homology search with MMseqs2 - Nature Methods
Graphics processing unit-accelerated MMseqs2 offers tremendous speedups for homology retrieval from metagenomic databases, query-centered multiple sequence alignment generation for structure predictio...
www.nature.com
September 21, 2025 at 8:06 AM
MMseqs2-GPU sets new standards in single query search speed, allows near instant search of big databases, scales to multiple GPUs and is fast beyond VRAM. It enables ColabFold MSA generation in seconds and sub-second Foldseek search against AFDB50. 1/n
📄 www.nature.com/articles/s41...
💿 mmseqs.com
📄 www.nature.com/articles/s41...
💿 mmseqs.com
Years ago we discovered that missense mutations in homomeric proteins often induces their supramolecular assembly, as in the 📽️👇 - Are such aberrant assemblies of *folded* proteins toxic? Surprisingly, NO. Cells are amazingly robust systems! Paper now online @molsystbiol.org doi.org/10.1038/s443...
September 16, 2025 at 4:22 PM
Years ago we discovered that missense mutations in homomeric proteins often induces their supramolecular assembly, as in the 📽️👇 - Are such aberrant assemblies of *folded* proteins toxic? Surprisingly, NO. Cells are amazingly robust systems! Paper now online @molsystbiol.org doi.org/10.1038/s443...
Reposted by Emmanuel Levy's lab
Congratulations @elevylab.bsky.social and collaborators for your latest publication in Cell 👏 and welcome to BlueSky 🦋@mocel.bsky.social @sciencesunige.bsky.social
Emmanuel Levy @elevylab.bsky.social has joined BlueSky 🌟 with a fantastic Cell paper with Shu-ou Shan, showing the interactome of the TOM complex and how cotranslational mito import prioritizes large globular domains. Beautiful science!
Give him a warm welcome 🎉
link: www.cell.com/cell/fulltex...
Give him a warm welcome 🎉
link: www.cell.com/cell/fulltex...
Principles of cotranslational mitochondrial protein import
Selective ribosome profiling reveals that nearly 20% of mitochondrial proteins in
human cells are imported during translation on cytosolic ribosomes. Cotranslational
import requires an N-terminal pres...
www.cell.com
August 22, 2025 at 6:51 AM
Congratulations @elevylab.bsky.social and collaborators for your latest publication in Cell 👏 and welcome to BlueSky 🦋@mocel.bsky.social @sciencesunige.bsky.social