Panagiotis Eleftheriadis
@elefp.bsky.social
Ph.D. candidate • Circuit/Systems Neuroscience and Behavior @bahllab.bsky.social • IMPRS_QBEE • Research Associate @HarvardOEB • M.Sc. from GSN @LMU_Muenchen
Pinned
Peptidergic modulation of motor neuron output via CART signaling at C bouton synapses | PNAS
The intensity of muscle contraction, and therefore movement vigor, needs to be adaptable
to enable complex motor behaviors. This can be achieved by...
www.pnas.org
Also pinned here! Our paper that reveals the CART peptide as a novel modulator of motor output in demanding tasks! @pnas.org
www.pnas.org/doi/abs/10.1...
www.pnas.org/doi/abs/10.1...
Reposted by Panagiotis Eleftheriadis
CeDNe: A multi-scale computational framework for modeling structure-function relationships in the C. elegans nervous system https://www.biorxiv.org/content/10.1101/2025.11.03.683805v1
November 5, 2025 at 8:15 AM
CeDNe: A multi-scale computational framework for modeling structure-function relationships in the C. elegans nervous system https://www.biorxiv.org/content/10.1101/2025.11.03.683805v1
Reposted by Panagiotis Eleftheriadis
Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
Zebrafish use spectral information to suppress the visual background
Vertebrate eyes first evolved in water, where spectral content rapidly fades with
distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the
background, pointing to distance es...
www.cell.com
November 4, 2025 at 9:16 AM
Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
Reposted by Panagiotis Eleftheriadis
sure, if you enjoy the horrifying limits of human perception
October 25, 2025 at 12:22 PM
sure, if you enjoy the horrifying limits of human perception
Reposted by Panagiotis Eleftheriadis
Out now in @currentbiology.bsky.social led by Kaarthik A Balakrishnan: We identify medullary circuits that represent the valence of thermal stimuli and control both long-term strategies of cold-avoidance and short term hot avoidance behaviors to enable thermoregulation. www.cell.com/current-biol...
Behavioral and circuit principles of temperature gradient navigation
Behavioral thermoregulation is critical for survival across animals. Balakrishnan
and Haesemeyer discover that thermoregulatory behavior in larval zebrafish is organized
into longer-term swim modes. T...
www.cell.com
October 24, 2025 at 2:57 PM
Out now in @currentbiology.bsky.social led by Kaarthik A Balakrishnan: We identify medullary circuits that represent the valence of thermal stimuli and control both long-term strategies of cold-avoidance and short term hot avoidance behaviors to enable thermoregulation. www.cell.com/current-biol...
Reposted by Panagiotis Eleftheriadis
What if you are a pixel in a higher-level consciousness navigating through extra dimensions of time? Meet the ‘Nested Observer Window Model’ of Jonathan Schooler, PhD, Distinguished Professor of Psychological and Brain Sciences UCSB.
www.essentiafoundation.org/12750-2/seei...
www.essentiafoundation.org/12750-2/seei...
Understanding consciousness as a fractal
What if you are a pixel in a higher-level consciousness navigating through extra dimensions of time? Meet the 'Nested Observer Window Model' of Jonathan Schooler, PhD, who is Distinguished Professor o...
www.essentiafoundation.org
October 3, 2025 at 7:49 PM
What if you are a pixel in a higher-level consciousness navigating through extra dimensions of time? Meet the ‘Nested Observer Window Model’ of Jonathan Schooler, PhD, Distinguished Professor of Psychological and Brain Sciences UCSB.
www.essentiafoundation.org/12750-2/seei...
www.essentiafoundation.org/12750-2/seei...
Reposted by Panagiotis Eleftheriadis
one of the cool things about rock climbing as a hobby is that you gradually lose the ability to be recognized by fingerprint scanners
September 29, 2025 at 5:17 PM
one of the cool things about rock climbing as a hobby is that you gradually lose the ability to be recognized by fingerprint scanners
Reposted by Panagiotis Eleftheriadis
How is valence computed in the brain? Check out our new preprint about a single cell that integrates excitatory and inhibitory input across modalities according to valence and impacts behavioral decisions. An exciting collaboration across many labs. Enjoy reading!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A multisensory, bidirectional, valence encoder guides behavioral decisions
A key function of the brain is to categorize sensory cues as repulsive or attractive and respond accordingly. While we have some understanding of how sensory information is processed in the sensory pe...
www.biorxiv.org
September 27, 2025 at 5:46 AM
How is valence computed in the brain? Check out our new preprint about a single cell that integrates excitatory and inhibitory input across modalities according to valence and impacts behavioral decisions. An exciting collaboration across many labs. Enjoy reading!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Panagiotis Eleftheriadis
👁️The retina — strikingly conserved across vertebrates, but an oddity among bilaterians!
So how did it evolve?
With @mikebok.bsky.social, @neurofishh.bsky.social and @denilsson.bsky.social, we argue that retinal complexity may 𝑝𝑟𝑒𝑑𝑎𝑡𝑒 𝑡ℎ𝑒 𝑒𝑦𝑒 𝑖𝑡𝑠𝑒𝑙𝑓.
www.biorxiv.org/content/10.1...
1/n
So how did it evolve?
With @mikebok.bsky.social, @neurofishh.bsky.social and @denilsson.bsky.social, we argue that retinal complexity may 𝑝𝑟𝑒𝑑𝑎𝑡𝑒 𝑡ℎ𝑒 𝑒𝑦𝑒 𝑖𝑡𝑠𝑒𝑙𝑓.
www.biorxiv.org/content/10.1...
1/n
a black and white dog is sitting on a couch with its tongue sticking out .
ALT: a black and white dog is sitting on a couch with its tongue sticking out .
media.tenor.com
September 12, 2025 at 12:58 PM
👁️The retina — strikingly conserved across vertebrates, but an oddity among bilaterians!
So how did it evolve?
With @mikebok.bsky.social, @neurofishh.bsky.social and @denilsson.bsky.social, we argue that retinal complexity may 𝑝𝑟𝑒𝑑𝑎𝑡𝑒 𝑡ℎ𝑒 𝑒𝑦𝑒 𝑖𝑡𝑠𝑒𝑙𝑓.
www.biorxiv.org/content/10.1...
1/n
So how did it evolve?
With @mikebok.bsky.social, @neurofishh.bsky.social and @denilsson.bsky.social, we argue that retinal complexity may 𝑝𝑟𝑒𝑑𝑎𝑡𝑒 𝑡ℎ𝑒 𝑒𝑦𝑒 𝑖𝑡𝑠𝑒𝑙𝑓.
www.biorxiv.org/content/10.1...
1/n
Reposted by Panagiotis Eleftheriadis
Congratulations to Anna Stöckl receiving the prestigious Walther-Arndt award from the German Zoological Society. #dzg2025 @anna-stoeckl.bsky.social 🥳🥂
September 11, 2025 at 5:34 PM
Congratulations to Anna Stöckl receiving the prestigious Walther-Arndt award from the German Zoological Society. #dzg2025 @anna-stoeckl.bsky.social 🥳🥂
Reposted by Panagiotis Eleftheriadis
Multiplexing behavioral signals in sensory representations https://www.biorxiv.org/content/10.1101/2025.09.04.674251v1
September 5, 2025 at 7:15 AM
Multiplexing behavioral signals in sensory representations https://www.biorxiv.org/content/10.1101/2025.09.04.674251v1
Amazing work on bee photoreceptors by my good friend @gkolyfetis.bsky.social!
Our findings on bees' photoreceptors are now officially published in Biology Letters of the Royal Society Publishing!! Thanks again for a productive collaboration @jjfosterlab.bsky.social and @gregoeur.bsky.social !!
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
I'm really happy to share the first preprint of my PhD work in @jjfosterlab.bsky.social! During a fruitful collaboration with @gregoeur.bsky.social, we uncovered a surprising feature of bees' eyes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 3, 2025 at 6:38 PM
Amazing work on bee photoreceptors by my good friend @gkolyfetis.bsky.social!
Reposted by Panagiotis Eleftheriadis
How do brains make decisions when faced with multiple, potentially conflicting cues? In our latest preprint, we show how #zebrafish use an additive strategy and process multiple visual features through anatomically distinct parallel pathways tinyurl.com/mvkn8em9 Thread 👇
August 25, 2025 at 9:02 AM
How do brains make decisions when faced with multiple, potentially conflicting cues? In our latest preprint, we show how #zebrafish use an additive strategy and process multiple visual features through anatomically distinct parallel pathways tinyurl.com/mvkn8em9 Thread 👇
Reposted by Panagiotis Eleftheriadis
It’s surreal to think that every neuron and synapse in the fly brain + cord that was dissected almost five years ago (the photo’s still on the lab slack!) is now just a click away on Codex codex.flywire.ai?dataset=banc. This wouldn’t have been possible without the incredible team behind it!
August 5, 2025 at 6:38 PM
It’s surreal to think that every neuron and synapse in the fly brain + cord that was dissected almost five years ago (the photo’s still on the lab slack!) is now just a click away on Codex codex.flywire.ai?dataset=banc. This wouldn’t have been possible without the incredible team behind it!
Reposted by Panagiotis Eleftheriadis
Hillel Adesnik lecturing in the MBL Visual Neuroscience course. Clear as a bell, as usual.
August 11, 2025 at 1:31 PM
Hillel Adesnik lecturing in the MBL Visual Neuroscience course. Clear as a bell, as usual.
Reposted by Panagiotis Eleftheriadis
Some zebrafish line eye dancing at @mblscience.bsky.social Visual Neuro course. Teaching OKR how John Dowling and Jim Fadool taught me during the zebrafish course.
August 9, 2025 at 5:11 PM
Some zebrafish line eye dancing at @mblscience.bsky.social Visual Neuro course. Teaching OKR how John Dowling and Jim Fadool taught me during the zebrafish course.
Reposted by Panagiotis Eleftheriadis
And today: Dave Zenisek and more ribbons!
@mblscience.bsky.social Visual Neuro course
@mblscience.bsky.social Visual Neuro course
August 3, 2025 at 10:17 PM
And today: Dave Zenisek and more ribbons!
@mblscience.bsky.social Visual Neuro course
@mblscience.bsky.social Visual Neuro course
Reposted by Panagiotis Eleftheriadis
Day 1 of the Visual Neuroscience course at the MBL in Woods Hole. The legendary John Dowling and Michael Do, both from Harvard, gave fabulous intro lectures on photoreceptors And the lab is humming! Can’t wait for day 2!
August 2, 2025 at 9:38 PM
Day 1 of the Visual Neuroscience course at the MBL in Woods Hole. The legendary John Dowling and Michael Do, both from Harvard, gave fabulous intro lectures on photoreceptors And the lab is humming! Can’t wait for day 2!
Reposted by Panagiotis Eleftheriadis
The Behavioural Neurobiology Summer School in Kosovo is back for the 2nd year and after just a few days we already made it onto live TV! For anyone who speaks Albanian, you can check out the full broadcast here: shorturl.at/kpUzp 🎙️
July 11, 2025 at 10:58 AM
The Behavioural Neurobiology Summer School in Kosovo is back for the 2nd year and after just a few days we already made it onto live TV! For anyone who speaks Albanian, you can check out the full broadcast here: shorturl.at/kpUzp 🎙️
Reposted by Panagiotis Eleftheriadis
Seeing the world through the lens of oscillations - we are delighted to share our new paper where we demonstrate that anatomically resolved oscillatory bursts reveal dynamic motifs of thalamocortical activity during naturalistic stimulus viewing (doi.org/10.1016/j.ne...).
July 10, 2025 at 9:06 PM
Seeing the world through the lens of oscillations - we are delighted to share our new paper where we demonstrate that anatomically resolved oscillatory bursts reveal dynamic motifs of thalamocortical activity during naturalistic stimulus viewing (doi.org/10.1016/j.ne...).
Check out this amazing work by my friend and colleague @maxcapelle.bsky.social !!
We are proud to have @maxcapelle.bsky.social's paper out on bioRxiv! He found that phototactic behavior in #zebrafish switches during #ontogeny🐟🔆 Through elegant behavioral dissections, he identifies the navigational strategies related to this transition. www.biorxiv.org/content/10.1... Thread 👇
June 23, 2025 at 1:11 PM
Check out this amazing work by my friend and colleague @maxcapelle.bsky.social !!
Reposted by Panagiotis Eleftheriadis
We just pushed “Memory by a 1000 rules” onto bioRxiv, where we use clever #ML to find #plasticity quadruplets (EE, EI, IE, II) that learn basic stability in spiking nets. Why is it cool? We find 1000s!! of solutions, and they don’t just stabilise. They #memorise! www.biorxiv.org/content/10.1...
Memory by a thousand rules: Automated discovery of functional multi-type plasticity rules reveals variety & degeneracy at the heart of learning
Synaptic plasticity is the basis of learning and memory, but the link between synaptic changes and neural function remains elusive. Here, we used automated search algorithms to obtain thousands of str...
www.biorxiv.org
June 2, 2025 at 6:50 PM
We just pushed “Memory by a 1000 rules” onto bioRxiv, where we use clever #ML to find #plasticity quadruplets (EE, EI, IE, II) that learn basic stability in spiking nets. Why is it cool? We find 1000s!! of solutions, and they don’t just stabilise. They #memorise! www.biorxiv.org/content/10.1...
Reposted by Panagiotis Eleftheriadis
New collaborative preprint with Losonczy Lab and Polleux Lab!
How does synaptic organization shape place fields in CA1 Pyramidal Neurons?
We mapped thousands of synapses & showed that clustering of excitatory inputs is key for tuning.
www.biorxiv.org/content/10.1...
#Neuroscience #bioRxiv
How does synaptic organization shape place fields in CA1 Pyramidal Neurons?
We mapped thousands of synapses & showed that clustering of excitatory inputs is key for tuning.
www.biorxiv.org/content/10.1...
#Neuroscience #bioRxiv
From Morphology to Computation: How Synaptic Organization Shapes Place Fields in CA1 Pyramidal Neurons
The synaptic mechanisms driving feature selectivity in specific neuron types remains a fundamental and unresolved challenge in neuroscience. In hippocampal CA1 pyramidal neurons (PNs), the development...
www.biorxiv.org
June 2, 2025 at 2:37 PM
New collaborative preprint with Losonczy Lab and Polleux Lab!
How does synaptic organization shape place fields in CA1 Pyramidal Neurons?
We mapped thousands of synapses & showed that clustering of excitatory inputs is key for tuning.
www.biorxiv.org/content/10.1...
#Neuroscience #bioRxiv
How does synaptic organization shape place fields in CA1 Pyramidal Neurons?
We mapped thousands of synapses & showed that clustering of excitatory inputs is key for tuning.
www.biorxiv.org/content/10.1...
#Neuroscience #bioRxiv
Reposted by Panagiotis Eleftheriadis
Just out in Lab Animal: our new global multi-lab zebrafish study is live! Housing and husbandry variables can significantly alter zebrafish anxiety-like behaviour. This is a call for better reporting and #standardisation in #zebrafish research. @uniofsurrey.bsky.social
Open access: rdcu.be/enHLj
Open access: rdcu.be/enHLj
Housing and husbandry factors affecting zebrafish novel tank test responses: a global multi-laboratory study
Lab Animal - This Article presents the results of a global multi-laboratory study assessing the effects of housing conditions and experimental settings on novel tank test responses in adult zebrafish.
rdcu.be
May 26, 2025 at 10:33 AM
Just out in Lab Animal: our new global multi-lab zebrafish study is live! Housing and husbandry variables can significantly alter zebrafish anxiety-like behaviour. This is a call for better reporting and #standardisation in #zebrafish research. @uniofsurrey.bsky.social
Open access: rdcu.be/enHLj
Open access: rdcu.be/enHLj
Reposted by Panagiotis Eleftheriadis
I am excited to share our new paper on anchovy retina connectomics! This was a great collaboration with Prof. Heß at LMU Munich and an incredible opportunity to explore neural circuitry in a unique visual system.
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
Horizontal cell connectivity in the anchovy retina—a 3D electron microscopic study - BMC Biology
Background Block-face scanning electron microscopy has opened a new era of connectomics research, in which it is possible to make dense reconstructions of all cells in a clipping of a neuronal network...
bmcbiol.biomedcentral.com
May 20, 2025 at 7:45 AM
I am excited to share our new paper on anchovy retina connectomics! This was a great collaboration with Prof. Heß at LMU Munich and an incredible opportunity to explore neural circuitry in a unique visual system.
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
Reposted by Panagiotis Eleftheriadis
I'm really happy to share the first preprint of my PhD work in @jjfosterlab.bsky.social! During a fruitful collaboration with @gregoeur.bsky.social, we uncovered a surprising feature of bees' eyes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
May 4, 2025 at 8:34 AM
I'm really happy to share the first preprint of my PhD work in @jjfosterlab.bsky.social! During a fruitful collaboration with @gregoeur.bsky.social, we uncovered a surprising feature of bees' eyes!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...