Exciting Instruments
@ei-science.bsky.social
Built to unlock the power of single-molecule fluorescence spectroscopy
🚨 Happening this Thursday! @timcraggs.bsky.social and @shenk0128.bsky.social discussing:
→ cutting-edge single-molecule science
→ insights into the mechanism and regulation of the Rag GTPase heterodimer
Register here: buff.ly/GcdLpHI #seminar #proteins #singlemolecule #biophysics #biochemistry
→ cutting-edge single-molecule science
→ insights into the mechanism and regulation of the Rag GTPase heterodimer
Register here: buff.ly/GcdLpHI #seminar #proteins #singlemolecule #biophysics #biochemistry
November 18, 2025 at 8:29 AM
🚨 Happening this Thursday! @timcraggs.bsky.social and @shenk0128.bsky.social discussing:
→ cutting-edge single-molecule science
→ insights into the mechanism and regulation of the Rag GTPase heterodimer
Register here: buff.ly/GcdLpHI #seminar #proteins #singlemolecule #biophysics #biochemistry
→ cutting-edge single-molecule science
→ insights into the mechanism and regulation of the Rag GTPase heterodimer
Register here: buff.ly/GcdLpHI #seminar #proteins #singlemolecule #biophysics #biochemistry
⚡ What do you get when you combine a meaningful mission, innovative solutions, and an epic group of people? Something extremely Exciting 😉 We're looking for brilliant people to fill these roles & more > excitinginstruments.com/careers/
#lifesciencejobs #startupjobs #sheffieldjobs #hiring #scaleup
#lifesciencejobs #startupjobs #sheffieldjobs #hiring #scaleup
November 12, 2025 at 9:15 AM
⚡ What do you get when you combine a meaningful mission, innovative solutions, and an epic group of people? Something extremely Exciting 😉 We're looking for brilliant people to fill these roles & more > excitinginstruments.com/careers/
#lifesciencejobs #startupjobs #sheffieldjobs #hiring #scaleup
#lifesciencejobs #startupjobs #sheffieldjobs #hiring #scaleup
Join Kuang and @timcraggs.bsky.social on 20th November to discuss his findings in more detail as part of our next Exciting Seminar - 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi... 🧵 4/4
#structuralbiology #biophysics
#structuralbiology #biophysics
November 11, 2025 at 9:53 AM
Join Kuang and @timcraggs.bsky.social on 20th November to discuss his findings in more detail as part of our next Exciting Seminar - 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi... 🧵 4/4
#structuralbiology #biophysics
#structuralbiology #biophysics
🇨🇭 Meet Roman at #PSDI2025 (poster PO21) to see how our tools reveal drug-induced conformational changes, bringing static structures to life. Then 🇦🇹 join him & Tim at the 8th Austrian Cryo-EM Symposium. DM us to connect! #cryoem #drugdiscovery #structuralbiology
November 10, 2025 at 8:22 AM
🇨🇭 Meet Roman at #PSDI2025 (poster PO21) to see how our tools reveal drug-induced conformational changes, bringing static structures to life. Then 🇦🇹 join him & Tim at the 8th Austrian Cryo-EM Symposium. DM us to connect! #cryoem #drugdiscovery #structuralbiology
📢 Our Exciting Seminars are back! Join @timcraggs.bsky.social & @shenk0128.bsky.social on Nov 20 for 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi...
#biophysics #lifescienceevent #molecularmedicine #biochemistry #smfret
#biophysics #lifescienceevent #molecularmedicine #biochemistry #smfret
November 7, 2025 at 10:06 AM
📢 Our Exciting Seminars are back! Join @timcraggs.bsky.social & @shenk0128.bsky.social on Nov 20 for 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi...
#biophysics #lifescienceevent #molecularmedicine #biochemistry #smfret
#biophysics #lifescienceevent #molecularmedicine #biochemistry #smfret
✨ Watch Dr Erin Cutts use the EI-FLEX and imagine the discoveries you could make yourself! We’re offering labs and core facilities a 2 month EI-FLEX trial at no cost. Run your own samples and see the data for yourself. Apply by Dec 15 → bit.ly/4ojRDhF
#singlemolecule #biophysics #lifescience
#singlemolecule #biophysics #lifescience
November 4, 2025 at 9:25 AM
✨ Watch Dr Erin Cutts use the EI-FLEX and imagine the discoveries you could make yourself! We’re offering labs and core facilities a 2 month EI-FLEX trial at no cost. Run your own samples and see the data for yourself. Apply by Dec 15 → bit.ly/4ojRDhF
#singlemolecule #biophysics #lifescience
#singlemolecule #biophysics #lifescience
How can our stable, compact, and easy-to-use single-molecule tools bring your static models to life? Check out the poster our Senior Application Scientist shared at last week’s Advances in Structural Analysis of Biomolecules conference👇 #structuralbiology #singlemolecule #molecularbiology
October 29, 2025 at 1:07 PM
How can our stable, compact, and easy-to-use single-molecule tools bring your static models to life? Check out the poster our Senior Application Scientist shared at last week’s Advances in Structural Analysis of Biomolecules conference👇 #structuralbiology #singlemolecule #molecularbiology
Cut prep time, skip immobilisation, and get real-time molecular insights with Fluorescence Correlation Spectroscopy (FCS).
✓ In-solution, label–mix–measure
✓ Setup in a day
✓ First results in minutes
Spend less time prepping, more time discovering. Find out more > bit.ly/47pRqm1
#fcs #kinetics
✓ In-solution, label–mix–measure
✓ Setup in a day
✓ First results in minutes
Spend less time prepping, more time discovering. Find out more > bit.ly/47pRqm1
#fcs #kinetics
October 27, 2025 at 2:09 PM
Cut prep time, skip immobilisation, and get real-time molecular insights with Fluorescence Correlation Spectroscopy (FCS).
✓ In-solution, label–mix–measure
✓ Setup in a day
✓ First results in minutes
Spend less time prepping, more time discovering. Find out more > bit.ly/47pRqm1
#fcs #kinetics
✓ In-solution, label–mix–measure
✓ Setup in a day
✓ First results in minutes
Spend less time prepping, more time discovering. Find out more > bit.ly/47pRqm1
#fcs #kinetics
Average doesn't really exist... so why measure it?
Our compact and easy-to-use instrument has been designed to help researchers access dynamic single-molecule insights from their own lab benchtops.
Find out more about the EI-FLEX and book a demo bit.ly/3KZK3Ku
#singlemolecule #smfret #fcs
Our compact and easy-to-use instrument has been designed to help researchers access dynamic single-molecule insights from their own lab benchtops.
Find out more about the EI-FLEX and book a demo bit.ly/3KZK3Ku
#singlemolecule #smfret #fcs
October 22, 2025 at 7:44 AM
Average doesn't really exist... so why measure it?
Our compact and easy-to-use instrument has been designed to help researchers access dynamic single-molecule insights from their own lab benchtops.
Find out more about the EI-FLEX and book a demo bit.ly/3KZK3Ku
#singlemolecule #smfret #fcs
Our compact and easy-to-use instrument has been designed to help researchers access dynamic single-molecule insights from their own lab benchtops.
Find out more about the EI-FLEX and book a demo bit.ly/3KZK3Ku
#singlemolecule #smfret #fcs
🚀 Join our mission to democratise single-molecule analysis! We’re hiring:
Scientific Creative Writer
Product Manager – Assay Kits
Field Application Scientists
Apply now 👉 excitinginstruments.com/careers?utm_...
#sheffieldjobs #startupjobs #lifescience #hiring
Scientific Creative Writer
Product Manager – Assay Kits
Field Application Scientists
Apply now 👉 excitinginstruments.com/careers?utm_...
#sheffieldjobs #startupjobs #lifescience #hiring
October 15, 2025 at 7:48 AM
🚀 Join our mission to democratise single-molecule analysis! We’re hiring:
Scientific Creative Writer
Product Manager – Assay Kits
Field Application Scientists
Apply now 👉 excitinginstruments.com/careers?utm_...
#sheffieldjobs #startupjobs #lifescience #hiring
Scientific Creative Writer
Product Manager – Assay Kits
Field Application Scientists
Apply now 👉 excitinginstruments.com/careers?utm_...
#sheffieldjobs #startupjobs #lifescience #hiring
Great chatting dynamic single-molecule data with brilliant scientists at the Crick yesterday! 🇩🇪 Next stop: Advances in Structural Analysis of Biomolecules at Charité Berlin, Oct 23–24. Don’t miss our Senior Application Scientist
Mahmoud’s poster - P017! #structuralbiology #chembiochem #chemphyschem
Mahmoud’s poster - P017! #structuralbiology #chembiochem #chemphyschem
October 14, 2025 at 1:05 PM
Great chatting dynamic single-molecule data with brilliant scientists at the Crick yesterday! 🇩🇪 Next stop: Advances in Structural Analysis of Biomolecules at Charité Berlin, Oct 23–24. Don’t miss our Senior Application Scientist
Mahmoud’s poster - P017! #structuralbiology #chembiochem #chemphyschem
Mahmoud’s poster - P017! #structuralbiology #chembiochem #chemphyschem
Join Tim Craggs, Paul Wheeler & the single-molecule community at The Francis Crick Institute, London - this Monday! ⚡ Dive into the latest single-molecule research, techniques & discoveries. Free to attend - reserve your spot: www.eventbrite.co.uk/e/single-mol...
#biophysics #molecularbiology
#biophysics #molecularbiology
October 9, 2025 at 7:32 AM
Join Tim Craggs, Paul Wheeler & the single-molecule community at The Francis Crick Institute, London - this Monday! ⚡ Dive into the latest single-molecule research, techniques & discoveries. Free to attend - reserve your spot: www.eventbrite.co.uk/e/single-mol...
#biophysics #molecularbiology
#biophysics #molecularbiology
🚀 Since spinning out in 2021, our journey has been an Exciting one! Thrilled to see our CEO & founder @timcraggs.bsky.social named Entrepreneur of the Month by Insider Magazine. Read Tim’s comment below and the article here 👉 flickread.com/edition/html...
#entrepreneur #singlemolecule #sheffield
#entrepreneur #singlemolecule #sheffield
October 2, 2025 at 8:30 AM
🚀 Since spinning out in 2021, our journey has been an Exciting one! Thrilled to see our CEO & founder @timcraggs.bsky.social named Entrepreneur of the Month by Insider Magazine. Read Tim’s comment below and the article here 👉 flickread.com/edition/html...
#entrepreneur #singlemolecule #sheffield
#entrepreneur #singlemolecule #sheffield
“Absolutely gorgeous!" That's how Edwin Antony describes the data from our EI-FLEX in his Exciting Seminar, where he discusses how DNA context regulates the myriad roles of RPA. Watch the seminar in full to learn more: youtu.be/r0yowVKdXUI
#DNA #singlemolecule #molecularbiology #structuralbiology
#DNA #singlemolecule #molecularbiology #structuralbiology
September 29, 2025 at 11:04 AM
“Absolutely gorgeous!" That's how Edwin Antony describes the data from our EI-FLEX in his Exciting Seminar, where he discusses how DNA context regulates the myriad roles of RPA. Watch the seminar in full to learn more: youtu.be/r0yowVKdXUI
#DNA #singlemolecule #molecularbiology #structuralbiology
#DNA #singlemolecule #molecularbiology #structuralbiology
🚀 Here comes the next big step in our Exciting journey! Thrilled to announce the appointment of Jonathan Rigby as the Chairman of our Board. Find out more about what it means for Exciting Instruments in the press release below.
#innovation #startups #biophysics #Sheffield #pressrelease
#innovation #startups #biophysics #Sheffield #pressrelease
September 25, 2025 at 9:18 AM
🚀 Here comes the next big step in our Exciting journey! Thrilled to announce the appointment of Jonathan Rigby as the Chairman of our Board. Find out more about what it means for Exciting Instruments in the press release below.
#innovation #startups #biophysics #Sheffield #pressrelease
#innovation #startups #biophysics #Sheffield #pressrelease
👋 At the Midlands Biophysics Network meeting today? So are we!
Visit our stand to chat about how we're bringing solution-based single-molecule techniques right to your benchtop - no extensive training required.
#midlandsbiophysicsnetworkmeeting #biophysics #singlemolecule #smfret #fcs
Visit our stand to chat about how we're bringing solution-based single-molecule techniques right to your benchtop - no extensive training required.
#midlandsbiophysicsnetworkmeeting #biophysics #singlemolecule #smfret #fcs
September 18, 2025 at 10:35 AM
👋 At the Midlands Biophysics Network meeting today? So are we!
Visit our stand to chat about how we're bringing solution-based single-molecule techniques right to your benchtop - no extensive training required.
#midlandsbiophysicsnetworkmeeting #biophysics #singlemolecule #smfret #fcs
Visit our stand to chat about how we're bringing solution-based single-molecule techniques right to your benchtop - no extensive training required.
#midlandsbiophysicsnetworkmeeting #biophysics #singlemolecule #smfret #fcs
Thrilled to see long-time #FRET experts moving into single-molecule work with our technology at McMaster University! Plus, our instrument now also supports University at Albany's core facility with #smFRET & #FCS! A very Exciting week! 🙌 #biophysics #singlemolecule #structuralbiology
September 18, 2025 at 8:13 AM
Thrilled to see long-time #FRET experts moving into single-molecule work with our technology at McMaster University! Plus, our instrument now also supports University at Albany's core facility with #smFRET & #FCS! A very Exciting week! 🙌 #biophysics #singlemolecule #structuralbiology
Tim and Paul are ready and waiting at the Biology and Physics of Prokaryotic Chromosomes conference to show you how in-solution, single-molecule fluorescence spectroscopy can help visualise structural dynamics of prokaryotic protein/DNA interactions. Visit our stand for a chat! #prokaryoticproteins
September 16, 2025 at 10:43 AM
Tim and Paul are ready and waiting at the Biology and Physics of Prokaryotic Chromosomes conference to show you how in-solution, single-molecule fluorescence spectroscopy can help visualise structural dynamics of prokaryotic protein/DNA interactions. Visit our stand for a chat! #prokaryoticproteins
Missing biomolecular dynamics at picomolar levels? The EI-FLEX makes single-molecule research quick and easy with precision and stability. Watch Dr. Quinn below and book a demo: excitinginstruments.com/contact-us/?...
#singlemolecule #structuralbiology #moleculardynamics #smFRET #FCS
#singlemolecule #structuralbiology #moleculardynamics #smFRET #FCS
September 16, 2025 at 8:38 AM
Missing biomolecular dynamics at picomolar levels? The EI-FLEX makes single-molecule research quick and easy with precision and stability. Watch Dr. Quinn below and book a demo: excitinginstruments.com/contact-us/?...
#singlemolecule #structuralbiology #moleculardynamics #smFRET #FCS
#singlemolecule #structuralbiology #moleculardynamics #smFRET #FCS
Discover how single-molecule fluorescence reveals transient DNA–protein interactions, kinetics and conformational changes, and more. Meet @timcraggs.bsky.social & Paul Wheeler at next week’s events - email info@excitinginstruments.com
to schedule! #biophysics #smfret #fcs
to schedule! #biophysics #smfret #fcs
September 11, 2025 at 8:57 AM
Discover how single-molecule fluorescence reveals transient DNA–protein interactions, kinetics and conformational changes, and more. Meet @timcraggs.bsky.social & Paul Wheeler at next week’s events - email info@excitinginstruments.com
to schedule! #biophysics #smfret #fcs
to schedule! #biophysics #smfret #fcs
💡 Measure fleeting protein encounters with ease - no dark rooms, bulky equipment, or extensive training. Our compact instrument delivers fast, publication-ready results from the bench in ambient light. 👉 bit.ly/4683zLQ #smFRET #FCS #biophysics #science
September 4, 2025 at 7:08 AM
💡 Measure fleeting protein encounters with ease - no dark rooms, bulky equipment, or extensive training. Our compact instrument delivers fast, publication-ready results from the bench in ambient light. 👉 bit.ly/4683zLQ #smFRET #FCS #biophysics #science
🚀 Hear ALEX and smFRET pioneer Shimon Weiss talk on origins, breakthroughs, and the future 👀 Watch the Exciting Seminar in full > youtu.be/MBI82_QKAnk
#smFRET #ALEX #biophysics #structuralbiology #moleculardynamics
#smFRET #ALEX #biophysics #structuralbiology #moleculardynamics
September 2, 2025 at 8:43 AM
🚀 Hear ALEX and smFRET pioneer Shimon Weiss talk on origins, breakthroughs, and the future 👀 Watch the Exciting Seminar in full > youtu.be/MBI82_QKAnk
#smFRET #ALEX #biophysics #structuralbiology #moleculardynamics
#smFRET #ALEX #biophysics #structuralbiology #moleculardynamics
⚡Discovery moves faster when your software keeps up. The EI-FLEX lets you visualise data in real time, validate assays with ease & share results. Publication-ready plots + full metadata for confidence in every experiment. Book a demo 👉 bit.ly/3JzwYXE #smFRET #FCS #structuralbiology #singlemolecule
September 1, 2025 at 8:54 AM
⚡Discovery moves faster when your software keeps up. The EI-FLEX lets you visualise data in real time, validate assays with ease & share results. Publication-ready plots + full metadata for confidence in every experiment. Book a demo 👉 bit.ly/3JzwYXE #smFRET #FCS #structuralbiology #singlemolecule
Single-molecule measurements in solution expose heterogeneity, rare events, and real-time dynamics without immobilisation, yielding precise kinetic and mechanistic insights. Learn more: excitinginstruments.com?utm_source=b... #proteindynamics #DNAproteininteractions #structuralbiology #biophysics
August 27, 2025 at 10:45 AM
Single-molecule measurements in solution expose heterogeneity, rare events, and real-time dynamics without immobilisation, yielding precise kinetic and mechanistic insights. Learn more: excitinginstruments.com?utm_source=b... #proteindynamics #DNAproteininteractions #structuralbiology #biophysics
Curious how FCS applies to stem cells, CRISPR/Cas9 models & isolated receptors at physiologically relevant protein levels? Watch Joelle Goulding’s Exciting Seminar on FCS in biological systems 👀 youtu.be/YzFw-TLG1Bk?... #fcs #biophysics
August 26, 2025 at 9:19 AM
Curious how FCS applies to stem cells, CRISPR/Cas9 models & isolated receptors at physiologically relevant protein levels? Watch Joelle Goulding’s Exciting Seminar on FCS in biological systems 👀 youtu.be/YzFw-TLG1Bk?... #fcs #biophysics