@edonato.bsky.social
Pinned
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling
Nature Cancer - Trumpp and colleagues develop a method to obtain long-term circulating tumor cell-derived organoids from individuals with metastatic breast cancer and identify the neuregulin...
rdcu.be
Let's start the 2025 with a blast 🎇. Out today on @naturecancer.bsky.social Würth et al., on HER3/NRG1 and FGFR1 compensatory mechanism in CTCs and how to hijack that for long term in vitro culture.
#CTC #breastcancer #liquidbiopsies #NGS #personalizedmedicine @dkfz.bsky.social #HISTEM
rdcu.be/d5pGe
#CTC #breastcancer #liquidbiopsies #NGS #personalizedmedicine @dkfz.bsky.social #HISTEM
rdcu.be/d5pGe
Honoured to have been involved in this study and happy to see it finally published in @bloodjournal.bsky.social. Big Kudos to #DarjaKarpova and #HectorHuerbaEncabo for driving the project 🥇🥇🥇. Read full article here: ashpublications.org/blood/articl...
March 12, 2025 at 8:27 PM
Honoured to have been involved in this study and happy to see it finally published in @bloodjournal.bsky.social. Big Kudos to #DarjaKarpova and #HectorHuerbaEncabo for driving the project 🥇🥇🥇. Read full article here: ashpublications.org/blood/articl...
🙏🙏Thanks🙏🙏@oncodaily.bsky.social and @elisabettabonzano.bsky.social for highlighting our recent paper on #HER3/NRG1 and #FGFR1 signaling in #CTC from #brestcancer patients published in @naturecancer.bsky.social @dkfz.bsky.social
Here the link 👇👇👇👇
rdcu.be/d61IZ
Here the link 👇👇👇👇
rdcu.be/d61IZ
January 21, 2025 at 1:04 PM
🙏🙏Thanks🙏🙏@oncodaily.bsky.social and @elisabettabonzano.bsky.social for highlighting our recent paper on #HER3/NRG1 and #FGFR1 signaling in #CTC from #brestcancer patients published in @naturecancer.bsky.social @dkfz.bsky.social
Here the link 👇👇👇👇
rdcu.be/d61IZ
Here the link 👇👇👇👇
rdcu.be/d61IZ
Interested in understanding how #CTCs colonize distant organs and resist to therapy? Go check the latest paper from #RobertoWürth from #AndreasTrumpp lab on @naturecancer.bsky.social...
🚨SpoilerAlert: we can hijack those mechanisms to establish long term in vitro #CTC derived #organoids
🚨SpoilerAlert: we can hijack those mechanisms to establish long term in vitro #CTC derived #organoids
Now online - Article
"Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling"
✏️by Roberto Würth & Andreas Trumpp and team
🔗https://www.nature.com/articles/s43018-024-00882-2?utm_source=bluesky&utm_medium=social&utm_campaign=natcancer
"Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling"
✏️by Roberto Würth & Andreas Trumpp and team
🔗https://www.nature.com/articles/s43018-024-00882-2?utm_source=bluesky&utm_medium=social&utm_campaign=natcancer
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling - Nature Cancer
Trumpp and colleagues develop a method to obtain long-term circulating tumor cell-derived organoids from individuals with metastatic breast cancer and identify the neuregulin 1–HER3 axis as important ...
www.nature.com
January 10, 2025 at 6:52 PM
Interested in understanding how #CTCs colonize distant organs and resist to therapy? Go check the latest paper from #RobertoWürth from #AndreasTrumpp lab on @naturecancer.bsky.social...
🚨SpoilerAlert: we can hijack those mechanisms to establish long term in vitro #CTC derived #organoids
🚨SpoilerAlert: we can hijack those mechanisms to establish long term in vitro #CTC derived #organoids
Let's start the 2025 with a blast 🎇. Out today on @naturecancer.bsky.social Würth et al., on HER3/NRG1 and FGFR1 compensatory mechanism in CTCs and how to hijack that for long term in vitro culture.
#CTC #breastcancer #liquidbiopsies #NGS #personalizedmedicine @dkfz.bsky.social #HISTEM
rdcu.be/d5pGe
#CTC #breastcancer #liquidbiopsies #NGS #personalizedmedicine @dkfz.bsky.social #HISTEM
rdcu.be/d5pGe
Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling
Nature Cancer - Trumpp and colleagues develop a method to obtain long-term circulating tumor cell-derived organoids from individuals with metastatic breast cancer and identify the neuregulin...
rdcu.be
January 3, 2025 at 6:49 PM
Let's start the 2025 with a blast 🎇. Out today on @naturecancer.bsky.social Würth et al., on HER3/NRG1 and FGFR1 compensatory mechanism in CTCs and how to hijack that for long term in vitro culture.
#CTC #breastcancer #liquidbiopsies #NGS #personalizedmedicine @dkfz.bsky.social #HISTEM
rdcu.be/d5pGe
#CTC #breastcancer #liquidbiopsies #NGS #personalizedmedicine @dkfz.bsky.social #HISTEM
rdcu.be/d5pGe
Reposted
Are you interested in understanding non-genetic therapy resistance mechanisms in cancer? Do you have previous bioinformatic experience with single-cell epigenomic data analysis? Then consider applying to this postdoctoral position in our division:
jobs.dkfz.de/en/jobs/1673...
jobs.dkfz.de/en/jobs/1673...
Bioinformatic Postdoc in Cancer Epigenomics
jobs.dkfz.de
December 30, 2024 at 9:07 AM
Are you interested in understanding non-genetic therapy resistance mechanisms in cancer? Do you have previous bioinformatic experience with single-cell epigenomic data analysis? Then consider applying to this postdoctoral position in our division:
jobs.dkfz.de/en/jobs/1673...
jobs.dkfz.de/en/jobs/1673...
Reposted
Join us at FMI as a Junior Group Leader! A unique opportunity to set up your lab in a vibrant international research institute with world-class research groups and facilities, generous core funding, a collegial and inclusive culture - and great colleagues 🤓!
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
December 16, 2024 at 1:46 PM
Join us at FMI as a Junior Group Leader! A unique opportunity to set up your lab in a vibrant international research institute with world-class research groups and facilities, generous core funding, a collegial and inclusive culture - and great colleagues 🤓!
Reposted
Extremely proud to see my PhD project exploring intra-tumor heterogeneity in complex karyotype AML finally out in @NatureGenet! 🎉 👩🏻🔬
They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5
www.nature.com/articles/s41...
They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5
www.nature.com/articles/s41...
Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype - Nature Genetics
An integrated single-cell multiomic analysis of complex karyotype acute myeloid leukemia characterizes intratumoral heterogeneity and highlights links to therapeutic sensitivities.
www.nature.com
November 25, 2024 at 4:31 PM
Extremely proud to see my PhD project exploring intra-tumor heterogeneity in complex karyotype AML finally out in @NatureGenet! 🎉 👩🏻🔬
They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5
www.nature.com/articles/s41...
They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5
www.nature.com/articles/s41...