Edoardo Gianni
edogia.bsky.social
Edoardo Gianni
@edogia.bsky.social
Postdoc @mrclmb.bsky.social playing around in the #RNAworld. Born at 358ppm. He/him.
Reposted by Edoardo Gianni
RosettaFold 3 is here! 🧬🚀

AtomWorks (the foundational data pipeline powering it) is perhaps the really most exciting part of this release!

Congratulations @simonmathis.bsky.social and team!!! ❤️

bioRxiv preprint: www.biorxiv.org/content/10.1...
August 15, 2025 at 1:26 PM
Reposted by Edoardo Gianni
New paper from my group rdcu.be/eoaRr "Trinucleotide substrates under pH–freeze–thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme" in Nature Chemistry — great collaboration with attwaterlab.uk.
Trinucleotide substrates under pH–freeze–thaw cycles enable open-ended exponential RNA replication by a polymerase ribozyme
Nature Chemistry - Models of abiotic RNA replication suffer from inherent product inhibition arising from the high stability of RNA duplexes. Now, it has been shown that RNA trinucleotide...
rdcu.be
May 29, 2025 at 3:55 PM
Reposted by Edoardo Gianni
we recently found some really neat RNA-guided DNA-cutting systems in phages. Despite remarkable similarities to CRISPR systems, including encoding guide RNAs in arrays, they appear entirely evolutionarily distinct (but definitely related to snoRNAs 🤓)
We decided to call them TIGR-Tas systems 🐯
March 1, 2025 at 12:18 AM
Reposted by Edoardo Gianni
RNAWorld xkcd.com/3002
October 23, 2024 at 10:21 PM