Dylan Terstege
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dterstege.bsky.social
Dylan Terstege
@dterstege.bsky.social
Neuroscientist | Cossart Lab Postdoc 🇫🇷 | Epp Lab PhD 🇨🇦 | Brain-Wide Networks of Neuronal Activity under Pathological and Physiological Conditions

https://dterstege.github.io
Pinned
🚨New paper from the Epp and Sargin Labs!🚨

We identified early sex- and region-specific impairments to parvalbumin interneurons (PV-INs) during Alzheimer’s Disease (AD) pathogenesis

www.science.org/doi/10.1126/...

Simplified highlights below:

🧵/15
Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer’s disease
Altered function, connectivity, and survival of parvalbumin-expressing neurons in the retrosplenial cortex in Alzheimer’s disease.
www.science.org
A little late posting this, but I defended my PhD thesis earlier this year! Big thanks to Jonathan Epp for his mentorship and support over the years - I can’t recommend his lab enough 🇨🇦

Also very excited to share that I’ve started a postdoc at @inmed.bsky.social with Rosa Cossart! 🇫🇷
November 7, 2025 at 5:47 PM
Reposted by Dylan Terstege
As our graduate program deadline approaches, we are recruiting motivated students to join our team. See details below:
New ad: Graduate (MSc / PhD) Student Positions – Neurophysiology of Autism Mouse Models – University of Calgary can-acn.org/graduate-msc... @deryasargin.bsky.social #neurojobs
September 18, 2025 at 6:51 PM
Reposted by Dylan Terstege
New ad: Graduate (MSc / PhD) Student Positions – Neurophysiology of Autism Mouse Models – University of Calgary can-acn.org/graduate-msc... @deryasargin.bsky.social #neurojobs
September 18, 2025 at 6:34 PM
Reposted by Dylan Terstege
July 21, 2025 at 4:00 PM
Reposted by Dylan Terstege
My first paper in the Sargin Lab 🥳 so grateful to have been able to work on this project

@deryasargin.bsky.social
@dterstege.bsky.social
@jonathanepp.bsky.social
#eNeuro | An Open-Source and Highly Adaptable Rodent Limited Bedding and Nesting Apparatus for Chronic Early Life Stress
vist.ly/3n8f76m
July 3, 2025 at 2:52 PM
Reposted by Dylan Terstege
A research team led by Dr. Jonathan Epp and Dr. Derya Sargin at the University of Calgary, funded by Brain Canada and Women’s Brain Health Initiative (WBHI), has identified a promising target for new Alzheimer’s disease treatments. bit.ly/45atSCf
May 23, 2025 at 5:38 PM
Reposted by Dylan Terstege
Female brain holds the key to understanding Alzheimer’s disease. Epp-Sargin lab collaboration led by @dterstege.bsky.social featuring @liisagalea.bsky.social is out in Science Advances. We uncover the mechanisms that make females more vulnerable to Alzheimer’s - in mouse models and human brains 🧠
April 30, 2025 at 6:55 PM
🚨New paper from the Epp and Sargin Labs!🚨

We identified early sex- and region-specific impairments to parvalbumin interneurons (PV-INs) during Alzheimer’s Disease (AD) pathogenesis

www.science.org/doi/10.1126/...

Simplified highlights below:

🧵/15
Impaired parvalbumin interneurons in the retrosplenial cortex as the cause of sex-dependent vulnerability in Alzheimer’s disease
Altered function, connectivity, and survival of parvalbumin-expressing neurons in the retrosplenial cortex in Alzheimer’s disease.
www.science.org
April 30, 2025 at 6:34 PM
Reposted by Dylan Terstege
The new issue of Science Advances (open-access) has multiple papers on women's health. These 2 are related to menopause, hormone replacement and brain health
www.science.org/toc/sciadv/c...
March 5, 2025 at 7:30 PM
Reposted by Dylan Terstege
Our work on the effect of SSRIs on brain metabolic activity, tau levels and cognition is out. Another study led by amazing-Dylan Terstege (now Dr. Terstege).

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
SSRIs reduce plasma tau and restore dorsal raphe metabolism in Alzheimer's disease
INTRODUCTION Tau pathology impacts neurodegeneration and cognitive decline in Alzheimer's disease (AD), with the dorsal raphe nucleus (DRN) being among the brain regions showing the earliest tau pat...
alz-journals.onlinelibrary.wiley.com
February 13, 2025 at 7:12 PM