Dr Shaz
drshaz.bsky.social
Dr Shaz
@drshaz.bsky.social
Research scientist - Applied Health, mixed method studies, abuse & violence, adult social care, cost evaluations, hyperemesis, molecular science, mass spec.
Pregnancy Sickness Support
Reposted by Dr Shaz
Find out more about the #socialwork role when care homes close in this blog swopresearch.wordpress.com/2025/04/01/a...
April 1, 2025 at 12:34 PM
Reposted by Dr Shaz
Achieving Closure @NIHR research culminated in the launch of a national study - Improving Outcomes when Care Homes Close: new policy, practice, training materials & video supporting
older people
families
care staff
social workers

www.birmingham.ac.uk/schools/soci...

Video: youtu.be/sfXAB2J7Lh8
March 20, 2025 at 12:40 PM
Reposted by Dr Shaz
New research on what happens to older people, families and care staff when care homes close - policy and practice guide & training video via www.birmingham.ac.uk/schools/soci...
March 30, 2025 at 8:36 PM
Reposted by Dr Shaz
Forensics: DHS/ICE bumbling on student visas leads to disenfranching foreign students in US universities. Then they admit it was illegal. 🧪

theintercept.com/2025/04/17/i...
Universities Told Students to Leave the Country. ICE Just Said They Didn’t Actually Have To.
When DHS erased students’ database records, universities said they had to leave. An ICE court filing says the students still had status.
theintercept.com
April 21, 2025 at 4:00 AM
Reposted by Dr Shaz
Study finds the Moderna mRNA-1273 vaccine has a ~100 nucleotide poly(A) tail. Rapid mRNA degradation starts as mψCmψAG is removed, impacting efficacy. PMID:40240603, Nature 2025, @Nature https://doi.org/10.1038/s41586-025-08842-1 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines | Nature
Despite the widespread use of mRNA vaccines against COVID-19, little is known about the metabolism of therapeutic RNAs. Here we use nanopore sequencing1–3 to analyse individual therapeutic mRNA molecules, focusing on their poly(A) tails. We show that the Moderna mRNA-1273 vaccine4 has a poly(A) tail of around 100 nucleotides, followed by an mΨCmΨAG sequence. In cell lines, mRNA-1273 undergoes rapid degradation initiated by mΨCmΨAG removal, followed by CCR4–NOT-mediated deadenylation. However, in medically relevant preclinical models, particularly in macrophages, mRNA-1273 poly(A) tails are extended to up to 200 nucleotides by the TENT5A poly(A) polymerase5–7, which is induced by the vaccine. Re-adenylation, which stabilizes target mRNAs, is consistently observed in synthetic mRNAs that encode proteins targeted to the endoplasmic reticulum, such as ovalbumin or antigens from Zika virus8 or the malaria parasite9. The extent of re-adenylation varies: the BioNTech–Pfizer BNT162b2 vaccine10
doi.org
April 21, 2025 at 6:10 AM
Achieving Closure @NIHR research culminated in the launch of a national study - Improving Outcomes when Care Homes Close: new policy, practice, training materials & video supporting
older people
families
care staff
social workers

www.birmingham.ac.uk/schools/soci...

Video: youtu.be/sfXAB2J7Lh8
March 20, 2025 at 12:40 PM
Reposted by Dr Shaz
Watch a special report on Hyperemesis Gravidarum on ITV tonight 3/3/2025 at 7pm!
It highlights the devastating impacts of HG on women and families.

Donating to PregnancySicknessSupport.com directly helps and supports women and saves lives.
www.itv.com/news/2025-03...
www.itv.com
March 3, 2025 at 10:21 AM
Watch a special report on Hyperemesis Gravidarum on ITV tonight 3/3/2025 at 7pm!
It highlights the devastating impacts of HG on women and families.

Donating to PregnancySicknessSupport.com directly helps and supports women and saves lives.
www.itv.com/news/2025-03...
www.itv.com
March 3, 2025 at 10:21 AM
Watch @channel4tv.bsky.social docuseries #GoBack

It’s brilliantly done!!

Well done to #Channel4 for making this. Well done the participants (except 1 ) - that was an incredible and heartbreaking experience.

Those White Cliffs of Dover looked like paradise! They’re a beacon of hope to survivors.
Are any of you in the UK watching #GOBACK on Channel Four right now? As a Brit, I am fucking disgusted by the ignorance that has bred the racism within the majority of the participants! They should be ashamed of themselves! I’m ashamed of them!
February 12, 2025 at 11:33 PM
@amylougrove.bsky.social Hi Amy, thank you for a great masterclass lecture.

Can’t wait for the next one! Shaz. Xx
February 4, 2025 at 1:42 PM
Important mixed method study highlighting the improvement in mental health, chronic pain and other markers.
February 2, 2025 at 11:03 AM
The artwork was created to go along with my research from this paper:

scholar.google.com.au/scholar?hl=e...
February 2, 2025 at 11:01 AM
@pkpd-babe.bsky.social can you please add me to the science feed
January 30, 2025 at 11:18 AM
@physgal.bsky.social can you please add me to the science feed
January 30, 2025 at 11:17 AM
@ydnew.bsky.social can you please add me to the science feed
January 30, 2025 at 11:16 AM
@emmmilygz.bsky.social can you please add me to the science feed.
January 30, 2025 at 11:15 AM
Reposted by Dr Shaz
The number of Britons saying the UK was right to vote to leave the EU has hit its lowest level since the referendum, ahead of the fifth anniversary of Brexit on Friday

Right to vote to leave: 30%
January 29, 2025 at 3:03 PM
#PregnancySicknessSupport UK’s only charity supporting women and their families suffering Hyperemesis Gravidarum and nausea & vomiting in pregnancy has issued its impact report, benefitting its members, health professionals.

Download the report here: ow.ly/kSAX50UNXAQ

twitter.com/drshazee/sta...
Dr. S. Zafar on X: "The amazing beneficial impact of @HGSupportUK on sufferers of hyperemesis, their families and healthcare professionals. Read the impact report here. 👇" / X
The amazing beneficial impact of @HGSupportUK on sufferers of hyperemesis, their families and healthcare professionals. Read the impact report here. 👇
twitter.com
January 30, 2025 at 10:55 AM
Pregnancy Sickness Support is UK’s only charity supporting women and their families suffering from the debilitating condition Hyperemesis Gravidarum.

Look us up if you need help.
Health professionals too. pregnancysicknesssupport.org.uk
January 7, 2025 at 10:01 AM
Reposted by Dr Shaz
Welcome folks!!! This group of volunteers are amazing. I might be biased.
We support anyone with HG in Ireland 🇮🇪 We offer information & support for patients, training for healthcare providers, and we campaign for better awareness, treatment & research into #hyperemesisgravidarum 🔬
Best way to keep in touch is email www.hyperemesis.ie/get-involved...
Newsletter : Hyperemesis Ireland
www.hyperemesis.ie
January 5, 2025 at 8:40 PM
Reposted by Dr Shaz
This is why we exist. This is the difference that early and proactive treatment can make to HG patients and their babies. Thanks to Trish in our support group for sharing with us.
#hyperemesisgravidarum
January 6, 2025 at 8:48 PM
Reposted by Dr Shaz
I don't want my fridge to have a camera or Wi-Fi. I don't want my dishwasher to be smart. I don't want my washing machine to text me.

In fact, I kinda miss knobs and dials and knowing big appliances would last 20 years and could still be repaired.
January 5, 2025 at 10:07 AM
Reposted by Dr Shaz
Political donations are institutionalized bribery.

Donors get access to policymakers, shape laws, tax privileges, lax regulations, govt contracts/subsidies, honours, power.

Banning political donations is a necessary step for free and fair elections and democracy
leftfootforward.org/2025/01/how-...
How our democracy has been hijacked by corporations and wealthy elites
The only effective remedy is to ban all private donations, or bribes, to political parties.
leftfootforward.org
January 4, 2025 at 12:18 PM
Reposted by Dr Shaz
As we start the New Year its perhaps a good time to remind ourselves (and everyone else) of the importance & benefits of membership of the ECHR
youtu.be/iSTN-h8NoyY?...
Reform UK leader Nigel Farage says public want to leave the ECHR - let’s put the record straight
YouTube video by Peter Stefanovic
youtu.be
January 2, 2025 at 5:38 PM