Dr Sanil Rege
drsanil.bsky.social
Dr Sanil Rege
@drsanil.bsky.social
Psychiatrist | Educator | Neuroscience Enthusiast | Exploring the intersection of biology, psychology & human behaviour | Sharing insights, ideas & stories to simplify complexity.
🚨Is this the worst question in psychiatry?
“How’s your mood?” ⁉️

Clinically, it tells us almost nothing.

“Mood” is not a feeling, not happiness, and not sadness -
but something far stranger:

A rolling measure of prediction success vs failure.

🎥 New video 👉
youtu.be/zUkm8jR6BM8
Your Brain Doesn’t Care If You’re Happy – Your Brain Wants THIS Instead
YouTube video by Dr. Rege
youtu.be
November 23, 2025 at 10:57 AM
New video 🚨 Modafinil vs Armodafinil

I cover:

-How they work on dopamine, norepinephrine, orexin & histamine

-Role in narcolepsy, shift work, sleep apnoea, depression & ADHD

-The idea of “performance debt”

-Side effects, and risks

Watch here👉 youtu.be/J3nzq2GIPUo
The Truth About Modafinil & Armodafinil: Not the Limitless Pill You Think
YouTube video by Dr. Rege
youtu.be
November 17, 2025 at 1:14 AM
Reposted by Dr Sanil Rege
If you deal with "chronic pain", this video will give you something to think about.
New video 👉Why Chronic Pain Persists: Neurobiological Mechanisms 🚨

I cover:
👉Why pain persists after tissues heal

👉Central sensitisation, neuroinflammation, descending inhibition

👉conceptualising pain beyond nociception.. the human aspects

Video 👉 youtu.be/ovMOmAbxbkQ?si…
Pain Isn’t in Your Body — It’s Your Brain’s ‘Danger Mode’
YouTube video by Dr. Rege
https://youtu.be/ovMOmAbxbkQ?si…
November 9, 2025 at 6:39 PM
New video 👉Why Chronic Pain Persists: Neurobiological Mechanisms 🚨

I cover:
👉Why pain persists after tissues heal

👉Central sensitisation, neuroinflammation, descending inhibition

👉conceptualising pain beyond nociception.. the human aspects

Video 👉 youtu.be/ovMOmAbxbkQ?si…
Pain Isn’t in Your Body — It’s Your Brain’s ‘Danger Mode’
YouTube video by Dr. Rege
https://youtu.be/ovMOmAbxbkQ?si…
November 8, 2025 at 2:20 PM
New video. 🚨

-Not about Ritalin or Dex.
-Not about making a child sit still or focus harder

This is about a core neurobiological system the Brain needs -
and the one modern childhood has systematically ‘stripped’ away.

The System is PLAY

Here’s why it matters 👉 youtu.be/PwmTLNUTWZQ?si…
Your ADHD Child Isn’t Misbehaving — Their Brain Is Trying To Tell You Something
YouTube video by Dr. Rege
https://youtu.be/PwmTLNUTWZQ?si…
November 1, 2025 at 11:20 AM
Reposted by Dr Sanil Rege
Very interesting. We know insufficient sleep reduces stimulant effectiveness, and once addressed this improves most cases where patients report medications seems less effective. Will have to start incorporating adenosine into those discussions. /1
October 18, 2025 at 2:02 PM
New video 🎥 The Dopamine Paradox🚨

“Doesn’t last long enough …
Not as strong”

Seeing more patients on increasingly higher stimulant doses, sometimes above recommended limits …

🚩 But when doses keep needing to go up, that’s a red flag clinicians need to notice.
👇

Link 👉 youtu.be/qYfrHCbGbbU?si…
When Dopamine Backfires: Why Too Much Can Make You Tired
YouTube video by Dr. Rege
https://youtu.be/qYfrHCbGbbU?si…
October 18, 2025 at 1:06 PM
Procrastination Isn’t Laziness — It’s a Dopamine Timing Glitch (and Here’s How to Fix It)
youtu.be/slwjAIaePPU
Procrastination Isn’t Laziness — It’s a Dopamine Timing Glitch (and Here’s How to Fix It)
YouTube video by Dr. Rege
youtu.be
October 12, 2025 at 4:49 PM
Kratom Explained: Stimulant, Opioid, or Danger? 🚨

Kratom is marketed as a natural remedy - but its effects are not without risks.

I break down:

👉Pharmacology
👉Short & Long Term Effects
👉Regulatory action and more... 

Link 👉 youtu.be/rEjIVyJsANM?...

#Kratom
Kratom: Stimulant, Opioid… or Risk You’re Overlooking?
YouTube video by Dr. Rege
youtu.be
September 27, 2025 at 12:49 PM
AuADHD & Stimulants 🚨
Ever had patients with ASD + ADHD respond atypically to stimulants?

“Makes me tired”
“I was anxious.”

I cover:

-Why the ‘autistic brain’ processes stimulants differently

-Clinical signs to watch for

-Strategies to improve outcomes

Video 👉 youtu.be/dLVzwNp9GMY?si…
ADHD & Autism (AuDHD): Why Stimulants Work Differently (and What to Try Instead)
YouTube video by Dr. Rege
https://youtu.be/dLVzwNp9GMY?si…
September 20, 2025 at 12:09 PM
𝐍𝐞𝐰 𝐫𝐞𝐥𝐞𝐚𝐬𝐞 🎥
𝐏𝐚𝐭𝐢𝐞𝐧𝐭𝐬 𝐨𝐟𝐭𝐞𝐧 𝐬𝐚𝐲: “𝐈 𝐣𝐮𝐬𝐭 𝐜𝐚𝐧’𝐭 𝐬𝐰𝐢𝐭𝐜𝐡 𝐨𝐟𝐟.”🚨

In this video, I explore the Default Mode Network (DMN) - the brain’s “overthinking circuit.”

Video 👉 youtu.be/JWpxycc6iKQ?si…
7 Science-Backed Habits to Switch Off Your Brain’s Overthinking Circuit
YouTube video by Dr. Rege
https://youtu.be/JWpxycc6iKQ?si…
August 24, 2025 at 7:52 AM
Interoceptive Awareness and its role in ADHD and ASD ‘Burnout’ 🚨

Interoceptive awareness is the brain’s ability to detect and integrate internal bodily signals

Video 👇
youtu.be/ONM8YifTjf4

In ADHD & Autism, brain regions like the insula or ACC can misread or miss key physiological signals.
ADHD Burnout & Autistic Meltdowns: The Hidden Brain Circuit
YouTube video by Dr. Rege
youtu.be
August 22, 2025 at 7:53 AM
Interoceptive Awareness and its role in ADHD and ASD ‘Burnout’ 🚨

Interoceptive awareness is the brain’s ability to detect and integrate internal bodily signals

Video 👇
youtu.be/ONM8YifTjf4
ADHD Burnout & Autistic Meltdowns: The Hidden Brain Circuit
YouTube video by Dr. Rege
youtu.be
August 16, 2025 at 2:49 PM
“Wired… and tired.”🚨

Often mislabelled as anxiety, this state is frequently driven by noradrenergic hyperarousal

In this video, I explore:

– The difference between anxiety, hyperarousal & agitation

– The circuits involved

-A 4-step practical framework

Video 👇 youtu.be/PHLSQVuNxv4?...
Wired All the Time? Your Brain Might Be Stuck in Overdrive (Not Anxiety)
YouTube video by Dr. Rege
youtu.be
August 10, 2025 at 9:42 AM
The average age of first porn exposure is just 11.*🚨

In this video, I explore:

1. How porn ‘hijacks’ dopamine & motivation

2. Brain changes

3. Hypersexual disorder & POPU

4. Evidence-based treatments

*range of surveys show ages between 10-13
How Porn Hijacks Your Brain — Addiction, Erectile Dysfunction & Dopamine Explained
YouTube video by Dr. Rege
https://youtu.be/Gul2SRqChpo?si…
August 3, 2025 at 11:05 AM
The Most Expensive Debt of All? Understanding Burnout as Performance Debt 🚨

In this video, I cover the neurobiology and strategies to start paying it back - clinically and practically 👇

🔗 👉 youtu.be/AP_GTgslEPM?si…#Burnoutu#PerformanceDebtb#MentalHealthth
Burnout Isn’t Laziness—It’s a Hidden Brain Shutdown Called Performance Debt
YouTube video by Dr. Rege
https://youtu.be/AP_GTgslEPM?si…
July 29, 2025 at 12:46 PM
New video 🚀- RFK Jr. went viral using methylene blue mid-flight. 🚨

But few realise what he was really taking.

In this video, I explain:

– MOA
– Dose-response & psychiatric implications
– Biohacking myths vs clinical pharmacology
– What clinicians & patients need to know
youtu.be/qDYzyq1WcyM
The Truth About Methylene Blue — Hidden MAOI Risks Biohackers Miss
YouTube video by Dr. Rege
youtu.be
July 4, 2025 at 9:23 PM
New video 🚨5 psychiatric phenomena so strange, they blur the line between reality and delusion. 🚀

5 Bizarre Psychiatric Syndromes You Won’t Believe Are Real
youtu.be/k6-VJ1c77QM
5 Bizarre Psychiatric Syndromes You Won’t Believe Are Real
YouTube video by Dr. Rege
youtu.be
June 27, 2025 at 9:50 AM
New video on the Dr Rege channel: 🚀

Still Tired After 10 Hours of Sleep? - Let’s try to Solve it …🚨

In this video, I go beyond diagnostic labels to take a problem-solving approach to fatigue.

🔗 Watch here 👇
youtu.be/TxC1WCtugBc

#Fatigue #Burnout #Neuroscience
Still Tired After 10 Hours of Sleep? Here’s How to Fix the Brain-Based Fatigue Trap
YouTube video by Dr. Rege
youtu.be
June 14, 2025 at 2:49 AM
High Achiever but Always Burnt Out? Hidden ADHD… or Survival Mode?
youtu.be/AtERZ0Rw5gA
High Achiever but Always Burnt Out? Hidden ADHD… or Survival Mode?
YouTube video by Dr. Rege
youtu.be
June 7, 2025 at 2:40 AM
🚨 New video on the Dr Rege Channel - Emotions as a signal 🎥

Emotions come from ‘emovere’- “to move out”.

They’re not problems to fix, but signals pointing to unmet needs and prediction mismatches.

🔗 👉 youtu.be/h7cEnI3atFE?si…
Suppressing Emotions? Here’s What It’s Doing to Your Brain (And How to Fix It)
YouTube video by Dr. Rege
https://youtu.be/h7cEnI3atFE?si…
May 31, 2025 at 10:02 AM
New video 🚨👉You're Not Treating a Label- You're Treating a Human ✅

Give me 5 minutes-and it might change the way you approach treatment.

If you don’t define the targets, you’re flying blind- no matter how “right” the diagnosis seems.

Here’s how to change that 👇

Video 👉 youtu.be/0TINiQeot3M?si…
Why Your Mental Health Treatment Isn’t Working—Fix This First
YouTube video by Dr. Rege
https://youtu.be/0TINiQeot3M?si…
May 23, 2025 at 1:09 PM
🚨 NEW - ADHD and Non Stimulants 🚀

ADHD meds = dopamine-spiking stimulants.

But is it hiding a long-term price?

I break down the non-stimulant options- from atomoxetine to a med that slashed symptom scores by ~50%.

Video 👉 youtu.be/I0JGVNWTZsM?si…

*General education only #adhdh#stimulantsts
ADHD Isn’t Just About Stimulants - The Meds You’re Missing
YouTube video by Dr. Rege
https://youtu.be/I0JGVNWTZsM?si…
May 17, 2025 at 1:49 AM
Antidepressants are just like heroin.🚨
That’s the claim.

And it’s dead wrong - in two completely different ways.

I break it down:
– What real addiction is
– Why SSRI withdrawal ≠ addiction
– The dangers of lazy science

Video 👇
youtu.be/_kVPN6goeTw
Are Antidepressants Like Heroin? Is RFK Jr. Wrong? — Here’s the Science
YouTube video by Dr. Rege
youtu.be
May 9, 2025 at 10:02 AM
The Overlooked Reason ADHD Treatment Fails - Fix This First
youtu.be/5giC7Hh0AmA
The Overlooked Reason ADHD Treatment Fails - Fix This First
YouTube video by Dr. Rege
youtu.be
April 26, 2025 at 11:47 AM