Marco Ruscone
drmarcoruscone.bsky.social
Marco Ruscone
@drmarcoruscone.bsky.social
Reposted by Marco Ruscone
Three #MCP servers for mechanistic modeling in #biology. A well-rounded example of making LLMs reliable for scientific applications.
#AIForScience
www.biorxiv.org/content/10.1...
Intelligent Tool Orchestration for Rapid Mechanistic Model Prototyping: MCP Servers as AI-Biology Interfaces
The construction of multicellular mechanistic models in systems biology typically requires months of literature research, programming expertise, and deep knowledge of specialized computational tools. ...
www.biorxiv.org
September 17, 2025 at 12:39 AM
Reposted by Marco Ruscone
Intelligent Tool Orchestration for Rapid Mechanistic Model Prototyping: MCP Servers as AI-Biology Interfaces https://www.biorxiv.org/content/10.1101/2025.09.10.675105v1
September 15, 2025 at 4:47 PM
Reposted by Marco Ruscone
A fun FYI: PhysiCell was first publicly presented in 2015, with first open source release in 2016.

So let's call 2025 our 10th anniversary! 🧪
January 15, 2025 at 4:58 PM
At the #Hanami High Level Symposium, my friend and colleagues Adam Smelko is presenting our new @PhysiCell formulation that allows for stretchable cellular membrane! We are still working on this, but I hope we will be able to give you updates vero soon!
January 14, 2025 at 11:02 AM
Reposted by Marco Ruscone
Our #PhysiBoSS tutorial is now available at Briefings in Bioinformatics: academic.oup.com/bib/article/.... Learn how to build #multiscale models with #Boolean intracellular signaling, without any code, using #PhysiCell Studio! Showing three simple examples, and an update of Ruscone's invasion model👇
November 8, 2024 at 7:05 PM