Cracking Shells
@crackingshells.bsky.social
We build open-source infrastructure to package, share, and deploy #MCP servers for scientific applications.
🔗 GitHub: github.com/CrackingShells
🐣 Early-stage, hackathon-driven, and growing.
🔗 GitHub: github.com/CrackingShells
🐣 Early-stage, hackathon-driven, and growing.
Just stumbled upon Augmented Nature's #MCP server collection for #LifeSciences. UniProt, AlphaFold, KEGG, PDB (and so many more!), all exposed via MCP:
🔗 github.com/Augmented-Na...
#AIForScience #Biology
🔗 github.com/Augmented-Na...
#AIForScience #Biology
Augmented Nature
Augmented Nature has 25 repositories available. Follow their code on GitHub.
github.com
November 12, 2025 at 7:38 AM
Just stumbled upon Augmented Nature's #MCP server collection for #LifeSciences. UniProt, AlphaFold, KEGG, PDB (and so many more!), all exposed via MCP:
🔗 github.com/Augmented-Na...
#AIForScience #Biology
🔗 github.com/Augmented-Na...
#AIForScience #Biology
Solid #MCP design patterns in @anthropic.com ’s latest: "Code execution with MCP: Building more efficient agents"
🔗 www.anthropic.com/engineering/...
Exactly the kind of resource to share with your coding agent before tackling a server. I appreciate the didactic effort. 🐣
#AIForScience
🔗 www.anthropic.com/engineering/...
Exactly the kind of resource to share with your coding agent before tackling a server. I appreciate the didactic effort. 🐣
#AIForScience
Code execution with MCP: building more efficient AI agents
Learn how code execution with the Model Context Protocol enables agents to handle more tools while using fewer tokens, reducing context overhead by up to 98.7%.
www.anthropic.com
November 5, 2025 at 3:28 PM
Solid #MCP design patterns in @anthropic.com ’s latest: "Code execution with MCP: Building more efficient agents"
🔗 www.anthropic.com/engineering/...
Exactly the kind of resource to share with your coding agent before tackling a server. I appreciate the didactic effort. 🐣
#AIForScience
🔗 www.anthropic.com/engineering/...
Exactly the kind of resource to share with your coding agent before tackling a server. I appreciate the didactic effort. 🐣
#AIForScience
Announcing our 2nd #MCP Hackathon – Nov 25-26 @ #RIKEN Kobe, Japan!
After a closed first edition in August, we’re back open to all! Join up to 50 researchers/engineers to build MCP servers for scientific applications.
🔗 Sign up: forms.gle/vhTcV4uGDK9f...
Details⬇️
#AIForScience #OpenScience
After a closed first edition in August, we’re back open to all! Join up to 50 researchers/engineers to build MCP servers for scientific applications.
🔗 Sign up: forms.gle/vhTcV4uGDK9f...
Details⬇️
#AIForScience #OpenScience
October 24, 2025 at 9:35 AM
Announcing our 2nd #MCP Hackathon – Nov 25-26 @ #RIKEN Kobe, Japan!
After a closed first edition in August, we’re back open to all! Join up to 50 researchers/engineers to build MCP servers for scientific applications.
🔗 Sign up: forms.gle/vhTcV4uGDK9f...
Details⬇️
#AIForScience #OpenScience
After a closed first edition in August, we’re back open to all! Join up to 50 researchers/engineers to build MCP servers for scientific applications.
🔗 Sign up: forms.gle/vhTcV4uGDK9f...
Details⬇️
#AIForScience #OpenScience
Last week at #ICSB2025, we shared how #MCP can make LLM-based agents reliable for #SystemsBiology.
MCP was barely known there. All the more reason for Cracking Shells to exist: simplifying onboarding for researchers.
#AIForScience
MCP was barely known there. All the more reason for Cracking Shells to exist: simplifying onboarding for researchers.
#AIForScience
October 11, 2025 at 10:07 PM
Last week at #ICSB2025, we shared how #MCP can make LLM-based agents reliable for #SystemsBiology.
MCP was barely known there. All the more reason for Cracking Shells to exist: simplifying onboarding for researchers.
#AIForScience
MCP was barely known there. All the more reason for Cracking Shells to exist: simplifying onboarding for researchers.
#AIForScience
Two #MCP servers on Docker Hub for scientific papers 📚
🔗 paper-search: hub.docker.com/r/mcp/paper-search
🔗 arxiv-mcp-server: hub.docker.com/r/mcp/arxiv-mcp-server
Useful for automating literature discovery in #AIForScience workflows. Have you tried them yet?
#MCP #OpenScience
🔗 paper-search: hub.docker.com/r/mcp/paper-search
🔗 arxiv-mcp-server: hub.docker.com/r/mcp/arxiv-mcp-server
Useful for automating literature discovery in #AIForScience workflows. Have you tried them yet?
#MCP #OpenScience
October 1, 2025 at 8:45 AM
Two #MCP servers on Docker Hub for scientific papers 📚
🔗 paper-search: hub.docker.com/r/mcp/paper-search
🔗 arxiv-mcp-server: hub.docker.com/r/mcp/arxiv-mcp-server
Useful for automating literature discovery in #AIForScience workflows. Have you tried them yet?
#MCP #OpenScience
🔗 paper-search: hub.docker.com/r/mcp/paper-search
🔗 arxiv-mcp-server: hub.docker.com/r/mcp/arxiv-mcp-server
Useful for automating literature discovery in #AIForScience workflows. Have you tried them yet?
#MCP #OpenScience
BioMCP: 24 #MCP tools for #biology 🧬
Shoutout to @genomoncology.bsky.social !
Search PubMed, ClinicalTrials, cBioPortal...Fetch genes/variants, expand disease synonyms, match trials to biomarkers, analyze OpenFDA safety data...
🔗 biomcp.org
(Had forgotten about that one🤦)
#AIForScience
Shoutout to @genomoncology.bsky.social !
Search PubMed, ClinicalTrials, cBioPortal...Fetch genes/variants, expand disease synonyms, match trials to biomarkers, analyze OpenFDA safety data...
🔗 biomcp.org
(Had forgotten about that one🤦)
#AIForScience
BioMCP
Biomedical Model Context Protocol Server
biomcp.org
September 30, 2025 at 12:39 PM
BioMCP: 24 #MCP tools for #biology 🧬
Shoutout to @genomoncology.bsky.social !
Search PubMed, ClinicalTrials, cBioPortal...Fetch genes/variants, expand disease synonyms, match trials to biomarkers, analyze OpenFDA safety data...
🔗 biomcp.org
(Had forgotten about that one🤦)
#AIForScience
Shoutout to @genomoncology.bsky.social !
Search PubMed, ClinicalTrials, cBioPortal...Fetch genes/variants, expand disease synonyms, match trials to biomarkers, analyze OpenFDA safety data...
🔗 biomcp.org
(Had forgotten about that one🤦)
#AIForScience
Last week's #DevLog
Hatch! 0.7.0 now lets you add MCP packages with one command—It's multi-dependencies and multi-host.
Finally some versatility for #MCP setup 🐣
Still a pre-release, bug fixes & docs in progress!
#AIForScience
Hatch! 0.7.0 now lets you add MCP packages with one command—It's multi-dependencies and multi-host.
Finally some versatility for #MCP setup 🐣
Still a pre-release, bug fixes & docs in progress!
#AIForScience
September 27, 2025 at 5:25 AM
Last week's #DevLog
Hatch! 0.7.0 now lets you add MCP packages with one command—It's multi-dependencies and multi-host.
Finally some versatility for #MCP setup 🐣
Still a pre-release, bug fixes & docs in progress!
#AIForScience
Hatch! 0.7.0 now lets you add MCP packages with one command—It's multi-dependencies and multi-host.
Finally some versatility for #MCP setup 🐣
Still a pre-release, bug fixes & docs in progress!
#AIForScience
AI Jam incoming in Japan!
trip.riken.jp/en/aijam/ind...
A hands-on event where scientists collaborate with LLMs from AWS, Anthropic, Google, and OpenAI to tackle challenging #research problems.
📆Dec 16-18: Main Session (Tokyo/Kobe) with on-site support from AI experts.
#AIForScience
trip.riken.jp/en/aijam/ind...
A hands-on event where scientists collaborate with LLMs from AWS, Anthropic, Google, and OpenAI to tackle challenging #research problems.
📆Dec 16-18: Main Session (Tokyo/Kobe) with on-site support from AI experts.
#AIForScience
Japan Scientist AI Jam Session 2025 | TRIP | Transformative Research Innovation Platform of RIKEN platforms
trip.riken.jp
September 22, 2025 at 8:18 AM
AI Jam incoming in Japan!
trip.riken.jp/en/aijam/ind...
A hands-on event where scientists collaborate with LLMs from AWS, Anthropic, Google, and OpenAI to tackle challenging #research problems.
📆Dec 16-18: Main Session (Tokyo/Kobe) with on-site support from AI experts.
#AIForScience
trip.riken.jp/en/aijam/ind...
A hands-on event where scientists collaborate with LLMs from AWS, Anthropic, Google, and OpenAI to tackle challenging #research problems.
📆Dec 16-18: Main Session (Tokyo/Kobe) with on-site support from AI experts.
#AIForScience
For #AIForScience stack, #MCP servers for databases are crucial.
A couple more of well-documented ones to explore:
🔗 Graph-based (for knowledge graphs): ArangoDB github.com/PCfVW/mcp-ar...
🔗 Document-based (for descriptive data): MongoDB github.com/mcp/mongodb-...
A couple more of well-documented ones to explore:
🔗 Graph-based (for knowledge graphs): ArangoDB github.com/PCfVW/mcp-ar...
🔗 Document-based (for descriptive data): MongoDB github.com/mcp/mongodb-...
Planning your 2025 tech stack? Here are 12 MCP Servers to try. These tools connect LLMs to essential services like GitHub, Slack, Google Drive, PostgreSQL, and more, unlocking powerful new workflow automations. The future of AI is connected.
#MCP #AI #Dev #TechStack
#MCP #AI #Dev #TechStack
September 18, 2025 at 3:06 AM
For #AIForScience stack, #MCP servers for databases are crucial.
A couple more of well-documented ones to explore:
🔗 Graph-based (for knowledge graphs): ArangoDB github.com/PCfVW/mcp-ar...
🔗 Document-based (for descriptive data): MongoDB github.com/mcp/mongodb-...
A couple more of well-documented ones to explore:
🔗 Graph-based (for knowledge graphs): ArangoDB github.com/PCfVW/mcp-ar...
🔗 Document-based (for descriptive data): MongoDB github.com/mcp/mongodb-...
Reposted by Cracking Shells
GitHub just launched the MCP Registry! It's the new place to find MCP Servers for any AI tool that speaks MCP, including GitHub Copilot and agents.
Find what you need faster at: github.blog/ai-and-ml/gi...
#GitHub #MCP #Developer #AI #OpenSource
Find what you need faster at: github.blog/ai-and-ml/gi...
#GitHub #MCP #Developer #AI #OpenSource
Home
Updates, ideas, and inspiration from GitHub to help developers build and design software.
github.blog
September 17, 2025 at 8:22 AM
GitHub just launched the MCP Registry! It's the new place to find MCP Servers for any AI tool that speaks MCP, including GitHub Copilot and agents.
Find what you need faster at: github.blog/ai-and-ml/gi...
#GitHub #MCP #Developer #AI #OpenSource
Find what you need faster at: github.blog/ai-and-ml/gi...
#GitHub #MCP #Developer #AI #OpenSource
Great to see the MCP tool scalability problem getting attention! As the article notes, it’s a critical bottleneck, but solutions are coming.
We’re tackling this too at Cracking Shells (ETA: December). The more minds on it, the faster we’ll crack it. 🐣
#MCP #AIForScience
We’re tackling this too at Cracking Shells (ETA: December). The more minds on it, the faster we’ll crack it. 🐣
#MCP #AIForScience
A new article tackles the MCP tool scalability/overload problem. Surprised by the lack of content on this, the author wrote an overview to explain the tooling bottleneck. An important read for the AI community.
t.co/imtblSlxE5
#AI #MCP #Tech #AITools
t.co/imtblSlxE5
#AI #MCP #Tech #AITools
September 18, 2025 at 1:50 AM
Great to see the MCP tool scalability problem getting attention! As the article notes, it’s a critical bottleneck, but solutions are coming.
We’re tackling this too at Cracking Shells (ETA: December). The more minds on it, the faster we’ll crack it. 🐣
#MCP #AIForScience
We’re tackling this too at Cracking Shells (ETA: December). The more minds on it, the faster we’ll crack it. 🐣
#MCP #AIForScience
Using the server itself as a layer helping to manage the tools is indeed within the benefit of #MCP we'd cite.
But the top one for us remains the encapsulation and being able to (almost) drop it anywhere. This is so convenient to decouple dev work from actual agent systems, particularly in #science
But the top one for us remains the encapsulation and being able to (almost) drop it anywhere. This is so convenient to decouple dev work from actual agent systems, particularly in #science
A great explanation for AI builders. This video answers: "What's the benefit of using MCP instead of just attaching tools directly to the agent?" Essential knowledge for anyone working with AI agents and building for the future.
#AIAgents #MCP #AITools #Developer
#AIAgents #MCP #AITools #Developer
September 17, 2025 at 12:53 AM
Three #MCP servers for mechanistic modeling in #biology. A well-rounded example of making LLMs reliable for scientific applications.
#AIForScience
www.biorxiv.org/content/10.1...
#AIForScience
www.biorxiv.org/content/10.1...
Intelligent Tool Orchestration for Rapid Mechanistic Model Prototyping: MCP Servers as AI-Biology Interfaces
The construction of multicellular mechanistic models in systems biology typically requires months of literature research, programming expertise, and deep knowledge of specialized computational tools. ...
www.biorxiv.org
September 17, 2025 at 12:39 AM
Three #MCP servers for mechanistic modeling in #biology. A well-rounded example of making LLMs reliable for scientific applications.
#AIForScience
www.biorxiv.org/content/10.1...
#AIForScience
www.biorxiv.org/content/10.1...
After reading the MCP Registry docs, a few thoughts:
1. Not a perfect fit for #MCP for #science (yet), but that’s okay because 👇
2. Recommend filtering of existing registries AND
3. Support for custom package registries: the whole point of Cracking Shells 🤩—MCP servers for scientific applications
1. Not a perfect fit for #MCP for #science (yet), but that’s okay because 👇
2. Recommend filtering of existing registries AND
3. Support for custom package registries: the whole point of Cracking Shells 🤩—MCP servers for scientific applications
September 9, 2025 at 1:19 AM
The MCP Registry is live! 🎉 Huge for tool discovery—especially if it works well for #MCP in #science.
At Cracking Shells, we’ve built our own solutions, but we’re all for interoperability. Excited to test, compare, and adapt to what serves the community best.
#AIForScience
At Cracking Shells, we’ve built our own solutions, but we’re all for interoperability. Excited to test, compare, and adapt to what serves the community best.
#AIForScience
Introducing the MCP Registry: a central, open-source hub for discovering and sharing MCP servers. It's like an app store for the agentic ecosystem, making it easier for developers to find and use tools.
Explore the repo:
github.com/modelcontext...
#MCP #AI #OpenSource #Developer
Explore the repo:
github.com/modelcontext...
#MCP #AI #OpenSource #Developer
September 8, 2025 at 11:56 PM
The MCP Registry is live! 🎉 Huge for tool discovery—especially if it works well for #MCP in #science.
At Cracking Shells, we’ve built our own solutions, but we’re all for interoperability. Excited to test, compare, and adapt to what serves the community best.
#AIForScience
At Cracking Shells, we’ve built our own solutions, but we’re all for interoperability. Excited to test, compare, and adapt to what serves the community best.
#AIForScience
Here is nome inspiration from real-world MCP workflows (Slack → Notion/HubSpot).
That could transfer to #LabAutomation e.g., routing logs from robotic systems or equipment notifications to research trackers.
That could work today with systems we already have.
#MCP #AIForScience
That could transfer to #LabAutomation e.g., routing logs from robotic systems or equipment notifications to research trackers.
That could work today with systems we already have.
#MCP #AIForScience
September 8, 2025 at 3:53 AM
Here is nome inspiration from real-world MCP workflows (Slack → Notion/HubSpot).
That could transfer to #LabAutomation e.g., routing logs from robotic systems or equipment notifications to research trackers.
That could work today with systems we already have.
#MCP #AIForScience
That could transfer to #LabAutomation e.g., routing logs from robotic systems or equipment notifications to research trackers.
That could work today with systems we already have.
#MCP #AIForScience
Reposted by Cracking Shells
For the open-source and decentralization folks: This session at the MCP Dev Summit is for you. Tadas Antanavicius and Toby Padilla are discussing the creation of an MCP Registry. A key step for the ecosystem.
London, Oct 2. Register at mcpdevsummit.ai
#OpenSource #Decentralization #AI #TechTalks
London, Oct 2. Register at mcpdevsummit.ai
#OpenSource #Decentralization #AI #TechTalks
September 4, 2025 at 5:08 PM
For the open-source and decentralization folks: This session at the MCP Dev Summit is for you. Tadas Antanavicius and Toby Padilla are discussing the creation of an MCP Registry. A key step for the ecosystem.
London, Oct 2. Register at mcpdevsummit.ai
#OpenSource #Decentralization #AI #TechTalks
London, Oct 2. Register at mcpdevsummit.ai
#OpenSource #Decentralization #AI #TechTalks
Reposted by Cracking Shells
For the tech and AI folks on Bluesky: Check out this talk from Andrew Culberson at the MCP Dev Summit. He's covering how MCP is the backbone for multi-agent, multi-user workspaces. A key topic for anyone building collaborative tools. See you in London on Oct 2.
#TechTalks #AIagents #LondonTech #MCP
#TechTalks #AIagents #LondonTech #MCP
September 2, 2025 at 4:37 PM
For the tech and AI folks on Bluesky: Check out this talk from Andrew Culberson at the MCP Dev Summit. He's covering how MCP is the backbone for multi-agent, multi-user workspaces. A key topic for anyone building collaborative tools. See you in London on Oct 2.
#TechTalks #AIagents #LondonTech #MCP
#TechTalks #AIagents #LondonTech #MCP
Last week, we hosted our first #MCP hackathon for science with 22 #researchers (computational physics, chemistry, biology).
None had used MCP or LLMs APIs before. By the end, they’d created their own MCP servers.
This was invite-only, but more events are coming! 🐣 #AIForScience
None had used MCP or LLMs APIs before. By the end, they’d created their own MCP servers.
This was invite-only, but more events are coming! 🐣 #AIForScience
September 2, 2025 at 11:48 AM
Last week, we hosted our first #MCP hackathon for science with 22 #researchers (computational physics, chemistry, biology).
None had used MCP or LLMs APIs before. By the end, they’d created their own MCP servers.
This was invite-only, but more events are coming! 🐣 #AIForScience
None had used MCP or LLMs APIs before. By the end, they’d created their own MCP servers.
This was invite-only, but more events are coming! 🐣 #AIForScience
Reposted by Cracking Shells
Security is non-negotiable. At the MCP Dev Summit in London, Vitor Balocco will present "MCP Security: The Exploit Playbook." A crucial session covering real-world exploits and defensive strategies for the age of autonomous agents.
🗓️ Oct 2|London
mcpdevsummit.ai
#MCPDevSummit #AISecurity #MCP #Ai
🗓️ Oct 2|London
mcpdevsummit.ai
#MCPDevSummit #AISecurity #MCP #Ai
September 2, 2025 at 5:21 AM
Security is non-negotiable. At the MCP Dev Summit in London, Vitor Balocco will present "MCP Security: The Exploit Playbook." A crucial session covering real-world exploits and defensive strategies for the age of autonomous agents.
🗓️ Oct 2|London
mcpdevsummit.ai
#MCPDevSummit #AISecurity #MCP #Ai
🗓️ Oct 2|London
mcpdevsummit.ai
#MCPDevSummit #AISecurity #MCP #Ai
#MCP isn’t the only way to connect LLMs to tools, but it won us over for #research:
Small: the decorator pattern of the Python SDK is a killer to wrap existing API
Decoupled: Devs build tools; users install them like packages (almost). Fits the ‘publish once, use anywhere’ model scientists like.
Small: the decorator pattern of the Python SDK is a killer to wrap existing API
Decoupled: Devs build tools; users install them like packages (almost). Fits the ‘publish once, use anywhere’ model scientists like.
August 27, 2025 at 12:26 AM
Cracking Shells is an open-source project to help #researchers integrate their scientific software with LLMs using the Model Context Protocol #MCP. We are building it because we need it, and maybe you do too 😉
We'll be sharing more about it. In the meantime, take a look: github.com/CrackingShells
We'll be sharing more about it. In the meantime, take a look: github.com/CrackingShells
Cracking Shells
Gathering and servicing MCP servers as packages for Science - Cracking Shells
github.com
August 25, 2025 at 7:22 AM
Cracking Shells is an open-source project to help #researchers integrate their scientific software with LLMs using the Model Context Protocol #MCP. We are building it because we need it, and maybe you do too 😉
We'll be sharing more about it. In the meantime, take a look: github.com/CrackingShells
We'll be sharing more about it. In the meantime, take a look: github.com/CrackingShells