Christophe Lachance-Brais
@drlachancebrais.bsky.social
Ph.D. in supramolecular and DNA chemistry from the Sleiman lab at McGill, currently postdoc in the Feringa lab in Groningen. Unapologetically pyromaniac, I like to think of myself as a wizard with chemistry powers 🔥🎇
Reposted by Christophe Lachance-Brais
RFK Jr’s ACIP pick, Martin Kulldorff, said one of the most disturbing images from the pandemic was a toddler crying about having to wear a mask. I see toddlers cry about everything all the time, and I found it far more disturbing to see refrigerator trucks full of body bags outside of the hospitals…
June 12, 2025 at 12:15 AM
RFK Jr’s ACIP pick, Martin Kulldorff, said one of the most disturbing images from the pandemic was a toddler crying about having to wear a mask. I see toddlers cry about everything all the time, and I found it far more disturbing to see refrigerator trucks full of body bags outside of the hospitals…
@mark-carney.bsky.social J'espère que vous êtes sûre de ce que vous faites... On semble donner une victoire à Trump quand il continue à ouvertement bafoué notre pays, nous menacer d'une invasion. Est-ce déjà le temps pour un deal? On ne vous a pas élu pour vous plier aux américains après tout...
June 12, 2025 at 5:44 AM
@mark-carney.bsky.social J'espère que vous êtes sûre de ce que vous faites... On semble donner une victoire à Trump quand il continue à ouvertement bafoué notre pays, nous menacer d'une invasion. Est-ce déjà le temps pour un deal? On ne vous a pas élu pour vous plier aux américains après tout...
Reposted by Christophe Lachance-Brais
Misha Lukin is now talking about doing quantum computing and error correction with arrays of neutral Rydberg atoms. I wrote about that here. #Helgoland2025
www.quantamagazine.org/the-best-qub...
www.quantamagazine.org/the-best-qub...
The Best Qubits for Quantum Computing Might Just Be Atoms | Quanta Magazine
In the search for the most scalable hardware to use for quantum computers, qubits made of individual atoms are having a breakout moment.
www.quantamagazine.org
June 11, 2025 at 9:05 AM
Misha Lukin is now talking about doing quantum computing and error correction with arrays of neutral Rydberg atoms. I wrote about that here. #Helgoland2025
www.quantamagazine.org/the-best-qub...
www.quantamagazine.org/the-best-qub...
Reposted by Christophe Lachance-Brais
Despite huge protein databanks and the use of AI tools like AlphaFold, a new previously overlooked covalent bonding motif has been revealed. #ChemSky #BioSky
An overlooked bonding motif appears in many more proteins than was previously realised
Covalent nitrogen-oxygen-sulfur linkages could be a new target for potential drugs
www.chemistryworld.com
June 11, 2025 at 12:23 PM
Reposted by Christophe Lachance-Brais
We have two new positions, a PhD and a Post doc at #InstituteofBiologyLeiden within our @microclockerc.bsky.social #ERCSyG project to discover interaction of #circadianclocks between Bacillus subtilis and Arabidopsis
please share these with your network! 🙏
links below👇
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please share these with your network! 🙏
links below👇
[1/3]
June 10, 2025 at 7:13 AM
We have two new positions, a PhD and a Post doc at #InstituteofBiologyLeiden within our @microclockerc.bsky.social #ERCSyG project to discover interaction of #circadianclocks between Bacillus subtilis and Arabidopsis
please share these with your network! 🙏
links below👇
[1/3]
please share these with your network! 🙏
links below👇
[1/3]
Thank you for taking the initiative and tackling the critical dangers AI development. We all want to have a future where AIs and humans work harmoniously together, rather than a dystopia pitting humans against machines.
Today marks a big milestone for me. I'm launching @law-zero.bsky.social, a nonprofit focusing on a new safe-by-design approach to AI that could both accelerate scientific discovery and provide a safeguard against the dangers of agentic AI.
Every frontier AI system should be grounded in a core commitment: to protect human joy and endeavour. Today, we launch LawZero, a nonprofit dedicated to advancing safe-by-design AI. lawzero.org
June 5, 2025 at 5:21 PM
Thank you for taking the initiative and tackling the critical dangers AI development. We all want to have a future where AIs and humans work harmoniously together, rather than a dystopia pitting humans against machines.
Reposted by Christophe Lachance-Brais
Is it possible to leverage AI to create functional RNAs? Well, from now yes! 🧪 Subscribe to get more like this 👉 plentyofroom.beehiiv.com/p/ai-rna-des... #AI #biotech
AI RNA Design: Generating Functional Molecules with Machine Learning!
AI RNA design: Advanced machine learning techniques create functional RNA molecules, from CRISPR guides to innovative toehold switches.
plentyofroom.beehiiv.com
May 28, 2025 at 3:59 AM
Is it possible to leverage AI to create functional RNAs? Well, from now yes! 🧪 Subscribe to get more like this 👉 plentyofroom.beehiiv.com/p/ai-rna-des... #AI #biotech
Another successful treatment in the rapidly expanding field of nucleic acid therapeutics! Glad to see this one coming from close to home, following intense collaboration between Canadian 🇨🇦and American 🇺🇸 doctors and scientists. 🧪🧬
ici.radio-canada.ca/nouvelle/216...
ici.radio-canada.ca/nouvelle/216...
Thérapie génique : première mondiale au CHU Sainte-Justine
La nouvelle technique permet de corriger pratiquement n'importe quelle mutation génétique et a essentiellement « guéri » un jeune homme de 18 ans.
ici.radio-canada.ca
May 23, 2025 at 3:48 PM
Another successful treatment in the rapidly expanding field of nucleic acid therapeutics! Glad to see this one coming from close to home, following intense collaboration between Canadian 🇨🇦and American 🇺🇸 doctors and scientists. 🧪🧬
ici.radio-canada.ca/nouvelle/216...
ici.radio-canada.ca/nouvelle/216...
A prescient article that goes beyond a single scandal to make a general "état de fait" of AI slop seeping through every aspect of society. On AI slop, "(AI tools) are not deployed by people trying to supplement or enrich their work and potential, but by those looking to automate it away entirely."
A “Heat Index” recently syndicated in at least two newspapers seemed like a normal summer guide—until readers noticed how much was made up. @damonberes.com and @cwarzel.bsky.social on the future of AI slop:
Slop the Presses
At least two newspapers published an insert littered with AI fabrications. How did this happen?
bit.ly
May 21, 2025 at 7:08 AM
A prescient article that goes beyond a single scandal to make a general "état de fait" of AI slop seeping through every aspect of society. On AI slop, "(AI tools) are not deployed by people trying to supplement or enrich their work and potential, but by those looking to automate it away entirely."
Thorough economic analysis of the impact of funding basic research. The US🇺🇸 had high basic science investment levels before and reaped the rewards, other countries, like Canada🇨🇦, should learn from that. 🧪 www.forbes.com/sites/johndr...
Trump’s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion Annually
Economists find public R&D drives U.S. productivity growth — and pays for itself
www.forbes.com
May 20, 2025 at 6:09 AM
Thorough economic analysis of the impact of funding basic research. The US🇺🇸 had high basic science investment levels before and reaped the rewards, other countries, like Canada🇨🇦, should learn from that. 🧪 www.forbes.com/sites/johndr...
What a hearthwarming story of a revolutionary gene-editing breakthrough! Hopefully little KJ will be the first of many patients with a rare genetic diseases to be cured with base-editing. 🧪🧬 www.nytimes.com/2025/05/15/h...
Baby Is Healed With World’s First Personalized Gene-Editing Treatment
www.nytimes.com
May 16, 2025 at 7:26 AM
What a hearthwarming story of a revolutionary gene-editing breakthrough! Hopefully little KJ will be the first of many patients with a rare genetic diseases to be cured with base-editing. 🧪🧬 www.nytimes.com/2025/05/15/h...
I applaud #OpenAI 's decision to keep the company non-profit. As a frequent ChatGPT user, I feel more comfortable knowing the AI is not geared to maximize shareholder income.
May 15, 2025 at 5:17 PM
I applaud #OpenAI 's decision to keep the company non-profit. As a frequent ChatGPT user, I feel more comfortable knowing the AI is not geared to maximize shareholder income.
Having a great time reading this review on architectural RNA (arcRNA). Do some common structural pattern used in nucleic acid nanotechnology, like DX junctions, could also be found in cells? 🧪🧬 www.sciencedirect.com/science/arti...
Architectural RNAs: A class of long noncoding RNAs functioning as scaffolds for membraneless organelles
Architectural RNAs (arcRNAs) are long noncoding RNAs that serve as structural scaffolds for membraneless organelles (MLOs), facilitating cellular orga…
www.sciencedirect.com
May 14, 2025 at 8:32 AM
Having a great time reading this review on architectural RNA (arcRNA). Do some common structural pattern used in nucleic acid nanotechnology, like DX junctions, could also be found in cells? 🧪🧬 www.sciencedirect.com/science/arti...
Mes félicitations à Mark Carney pour sa victoire électorale! J'espère qu'il fera bon sur sa parole et travaillera avec tout les autres partis, néo-democrate, conservateurs et bloquiste, pour présenter un front unis Canadien 🇨🇦 Elbows up
April 30, 2025 at 5:22 AM
Mes félicitations à Mark Carney pour sa victoire électorale! J'espère qu'il fera bon sur sa parole et travaillera avec tout les autres partis, néo-democrate, conservateurs et bloquiste, pour présenter un front unis Canadien 🇨🇦 Elbows up
A good read to quickly catch-up on the host of post-CRISPR tools being developed 🧪
“To do better than CRISPR is a very tall order”
The hunt to dethrone CRISPR as the most transformative biological discovery of the century is on
https://go.nature.com/42VS0Xn
The hunt to dethrone CRISPR as the most transformative biological discovery of the century is on
https://go.nature.com/42VS0Xn
Microbial warfare brought us CRISPR. What big breakthroughs could be next?
Gene editing and many other useful biotechnology tools came from studies of bacteria fighting off viral invaders. But scientists have only begun to unlock the secrets of this ancient arms race.
go.nature.com
April 23, 2025 at 2:47 PM
A good read to quickly catch-up on the host of post-CRISPR tools being developed 🧪
I bust my ass everyday doing #science in the hopes of helping society, and yet I'll never make a fraction of what politicians made playing the markets this week. How dare they talk of meritocracy?! #insidertrading
April 11, 2025 at 12:54 PM
I bust my ass everyday doing #science in the hopes of helping society, and yet I'll never make a fraction of what politicians made playing the markets this week. How dare they talk of meritocracy?! #insidertrading
A classic Trump play : take away everything to show that you can, then give back half and be seen as generous. We shouldn't be fools and rush to give concessions; it simply incentivize him to do it again and again.
April 10, 2025 at 4:27 AM
A classic Trump play : take away everything to show that you can, then give back half and be seen as generous. We shouldn't be fools and rush to give concessions; it simply incentivize him to do it again and again.
Reposted by Christophe Lachance-Brais
I received a heartbreaking email today: A paper in a special issue I’m editing is being retracted because one of its authors is afraid of losing their job and their legal status in the U.S. if they publish a scientific study on evolution. Yes, on evolution, nature's engine of diversity.
March 29, 2025 at 11:52 PM
I received a heartbreaking email today: A paper in a special issue I’m editing is being retracted because one of its authors is afraid of losing their job and their legal status in the U.S. if they publish a scientific study on evolution. Yes, on evolution, nature's engine of diversity.
This article focusing on the numbers shows the outsized importance of the #NIH in funding medical breakthrough ; it's unfortunate the president can't count. 🧪 www.nature.com/articles/d41...
How the NIH dominates the world’s health research — in charts
Abrupt cuts by the Trump administration to the US National Institutes of Health threaten progress in medical research globally.
www.nature.com
March 14, 2025 at 7:26 AM
This article focusing on the numbers shows the outsized importance of the #NIH in funding medical breakthrough ; it's unfortunate the president can't count. 🧪 www.nature.com/articles/d41...
Trudeau is going out like a Phoenix, giving his best speech so far. It includes a message for you Americans : "We don't want this." #tariffs 🇨🇦🇺🇸🇲🇽 Lâchons pas. youtu.be/83f47jIS_D8?...
FULL SPEECH | Trudeau outlines response to U.S. tariffs
YouTube video by CBC News
youtu.be
March 6, 2025 at 7:00 AM
Trudeau is going out like a Phoenix, giving his best speech so far. It includes a message for you Americans : "We don't want this." #tariffs 🇨🇦🇺🇸🇲🇽 Lâchons pas. youtu.be/83f47jIS_D8?...
What a ridiculous criminalisation of life-saving medicine! Neoluddites are using governments take science backwards. How did this perversive antiscience mentality take root after science saved so many lives during COVID?
March 4, 2025 at 6:49 AM
What a ridiculous criminalisation of life-saving medicine! Neoluddites are using governments take science backwards. How did this perversive antiscience mentality take root after science saved so many lives during COVID?
I'm so glad I decided to do a postdoc in Europe versus the US right now...
March 3, 2025 at 2:16 PM
I'm so glad I decided to do a postdoc in Europe versus the US right now...
Reposted by Christophe Lachance-Brais
Looking for a PhD candidate to join my group at the University of Zurich If you are an excellent and motivated student🧑🔬and want to integrate organic synthesis, photochemistry and redox chemistry in a research🧪 we want to know more about you! More info: www.stacko.group Appreciate sharing the post.
February 25, 2025 at 8:22 AM
Looking for a PhD candidate to join my group at the University of Zurich If you are an excellent and motivated student🧑🔬and want to integrate organic synthesis, photochemistry and redox chemistry in a research🧪 we want to know more about you! More info: www.stacko.group Appreciate sharing the post.
Reposted by Christophe Lachance-Brais
Explore transcriptional magic with GET! 🌟 An AI model decodes regulatory grammars in 213 human cell types using chromatin accessibility. #BiotechRevolution PMID:39779852, Nature 2025, @Nature https://doi.org/10.1038/s41586-024-08391-z 🧪
February 24, 2025 at 5:10 AM
Explore transcriptional magic with GET! 🌟 An AI model decodes regulatory grammars in 213 human cell types using chromatin accessibility. #BiotechRevolution PMID:39779852, Nature 2025, @Nature https://doi.org/10.1038/s41586-024-08391-z 🧪
Does anyone knows an app to convert pictures of molecular drawings or screenshots of papers into chemical structures (smiles, chemdraw, jsmol, etc.)? 🧪⚗️
February 21, 2025 at 6:26 AM
Does anyone knows an app to convert pictures of molecular drawings or screenshots of papers into chemical structures (smiles, chemdraw, jsmol, etc.)? 🧪⚗️