Professor James Hodge
@docfly.bsky.social
Bristol University (UK) neuroscientist interested in circadian rhythms, sleep, memory, neuropathies, neurodegenerative disease and Drosophila.
Reposted by Professor James Hodge
Making beta to alpha - see our latest work here pinning honey bee nicotinic acetylcholine receptor alpha8 gene into flies to test neonicotinoid sensitivity thanks to @annalassota.bsky.social and @docfly.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model - Scientific Reports
Scientific Reports - Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model
www.nature.com
October 17, 2025 at 7:26 AM
Making beta to alpha - see our latest work here pinning honey bee nicotinic acetylcholine receptor alpha8 gene into flies to test neonicotinoid sensitivity thanks to @annalassota.bsky.social and @docfly.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
We’ve not given up trying to work out what is killing the bees, with @matthiassoller.bsky.social @annalassota.bsky.social www.nature.com/articles/s41... Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model
Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model - Scientific Reports
Scientific Reports - Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model
www.nature.com
October 21, 2025 at 4:28 PM
We’ve not given up trying to work out what is killing the bees, with @matthiassoller.bsky.social @annalassota.bsky.social www.nature.com/articles/s41... Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model
Reposted by Professor James Hodge
Interested in what happens when a fly gets a bee receptor? 🐝➡️🪰
Check out our new paper!
Many thanks to @matthiassoller.bsky.social and @docfly.bsky.social
Check out our new paper!
Many thanks to @matthiassoller.bsky.social and @docfly.bsky.social
Making beta to alpha - see our latest work here pinning honey bee nicotinic acetylcholine receptor alpha8 gene into flies to test neonicotinoid sensitivity thanks to @annalassota.bsky.social and @docfly.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model - Scientific Reports
Scientific Reports - Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model
www.nature.com
October 17, 2025 at 10:08 AM
Interested in what happens when a fly gets a bee receptor? 🐝➡️🪰
Check out our new paper!
Many thanks to @matthiassoller.bsky.social and @docfly.bsky.social
Check out our new paper!
Many thanks to @matthiassoller.bsky.social and @docfly.bsky.social
Apply for a fully funded PhD studying CASK disease at the Hodge Bristol University with @gaynorasmith.bsky.social CASK research, Ben Housden, Doretta Caramaschi PhD Prof Sam Amin
gw4biomed.ac.uk/towards-a-be...
Developing and characterising new preclinical models and therapies
gw4biomed.ac.uk/towards-a-be...
Developing and characterising new preclinical models and therapies
September 3, 2025 at 3:15 PM
Apply for a fully funded PhD studying CASK disease at the Hodge Bristol University with @gaynorasmith.bsky.social CASK research, Ben Housden, Doretta Caramaschi PhD Prof Sam Amin
gw4biomed.ac.uk/towards-a-be...
Developing and characterising new preclinical models and therapies
gw4biomed.ac.uk/towards-a-be...
Developing and characterising new preclinical models and therapies
Reposted by Professor James Hodge
New Preprint from the lab, and the second half of Elizabeth Hodge’s masters project - we dived into whether shifts in visual #foraging behaviours and spatial #memory in #Heliconius involved changes in sensory systems🧪 1/n
Conservation of sensory pathways implies a localised change in the mushroom bodies is associated with cognitive evolution in Heliconius butterflies https://www.biorxiv.org/content/10.1101/2025.07.08.663516v1
July 13, 2025 at 1:53 PM
New Preprint from the lab, and the second half of Elizabeth Hodge’s masters project - we dived into whether shifts in visual #foraging behaviours and spatial #memory in #Heliconius involved changes in sensory systems🧪 1/n
9 months postdoc will be to continue our labs work development Drosophila models of CASK function and disease funded by caskresearch.org/cask-gene-di....
search for the job ACAD108170 from Here.
www.bristol.ac.uk/jobs/find/de...
search for the job ACAD108170 from Here.
www.bristol.ac.uk/jobs/find/de...
July 7, 2025 at 9:13 AM
9 months postdoc will be to continue our labs work development Drosophila models of CASK function and disease funded by caskresearch.org/cask-gene-di....
search for the job ACAD108170 from Here.
www.bristol.ac.uk/jobs/find/de...
search for the job ACAD108170 from Here.
www.bristol.ac.uk/jobs/find/de...
9 month Research Associate in fly CASK Neuroscience and Disease Models in Hodge lab (Physiology, Pharmacology and Neuroscience, Bristol University) available:
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
July 3, 2025 at 10:01 AM
9 month Research Associate in fly CASK Neuroscience and Disease Models in Hodge lab (Physiology, Pharmacology and Neuroscience, Bristol University) available:
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
Our BBSRC CircadiAgeing sLola project launches today with
@hughp.bsky.social @krasimiratsaneva.bsky.social @mino-belle.bsky.social @mbra3.bsky.social @alessiovagnoni.bsky.social studying clock excitability, circadian rhythms and healthy ageing
circadiageing.blogs.bristol.ac.uk
@hughp.bsky.social @krasimiratsaneva.bsky.social @mino-belle.bsky.social @mbra3.bsky.social @alessiovagnoni.bsky.social studying clock excitability, circadian rhythms and healthy ageing
circadiageing.blogs.bristol.ac.uk
July 1, 2025 at 5:01 PM
Our BBSRC CircadiAgeing sLola project launches today with
@hughp.bsky.social @krasimiratsaneva.bsky.social @mino-belle.bsky.social @mbra3.bsky.social @alessiovagnoni.bsky.social studying clock excitability, circadian rhythms and healthy ageing
circadiageing.blogs.bristol.ac.uk
@hughp.bsky.social @krasimiratsaneva.bsky.social @mino-belle.bsky.social @mbra3.bsky.social @alessiovagnoni.bsky.social studying clock excitability, circadian rhythms and healthy ageing
circadiageing.blogs.bristol.ac.uk
Research Associate in fly CASK Neuroscience and Disease Models in Hodge lab (Physiology, Pharmacology and Neuroscience, Bristol University)
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
Sign in to your account
www.bristol.ac.uk
June 26, 2025 at 12:52 PM
Research Associate in fly CASK Neuroscience and Disease Models in Hodge lab (Physiology, Pharmacology and Neuroscience, Bristol University)
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
www.bristol.ac.uk/jobs/find-in...
Fixed term until 30/04/2026
£38,249 - £44,128 per annum
Deadline 17th July.
Interviews 11th August.
ARUK Southwest – Bristol University Dementia research Public Patient involvement event Friday 19th September 10:30am-4:30pm Concorde Room, BAWA
589 Southmead Road, Filton, Bristol. BS34 7RF
Please RSVP: forms.office.com/e/nQUYGB8bjT
589 Southmead Road, Filton, Bristol. BS34 7RF
Please RSVP: forms.office.com/e/nQUYGB8bjT
June 11, 2025 at 8:35 AM
ARUK Southwest – Bristol University Dementia research Public Patient involvement event Friday 19th September 10:30am-4:30pm Concorde Room, BAWA
589 Southmead Road, Filton, Bristol. BS34 7RF
Please RSVP: forms.office.com/e/nQUYGB8bjT
589 Southmead Road, Filton, Bristol. BS34 7RF
Please RSVP: forms.office.com/e/nQUYGB8bjT
We have a 3 year postdoc in rodent circadian behaviour and ageing at University of Bristol
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
April 11, 2025 at 7:59 AM
We have a 3 year postdoc in rodent circadian behaviour and ageing at University of Bristol
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
Our @Edgar Buhl @Arni Majumdar new paper is out “Infantile Cerebellar‐Retinal Degeneration Associated With Novel ACO2 Variants: Clinical Features and Insights From a Drosophila Model” in Clinical Genetics doi.org/10.1111/cge....
Infantile Cerebellar‐Retinal Degeneration Associated With Novel ACO2 Variants: Clinical Features and Insights From a Drosophila Model
Our Translational Loop integrates patient genetic data with Drosophila models to study disease mechanisms. We identified ACO2 variants in a patient linked to ICRD and show that our animal model mirro...
doi.org
April 11, 2025 at 7:57 AM
Our @Edgar Buhl @Arni Majumdar new paper is out “Infantile Cerebellar‐Retinal Degeneration Associated With Novel ACO2 Variants: Clinical Features and Insights From a Drosophila Model” in Clinical Genetics doi.org/10.1111/cge....
bsky.app/profile/alzh... Please see our research using flies to study novel genes involved in Alzheimer's, thanks for the support BRACE
We recently spoke to Professor James Hodge at the University of Bristol, to learn more about his research into Alzheimer’s genes.
Using fruit flies, his work explores how these genes impact memory and sleep - key areas in dementia research.
@docfly.bsky.social
Using fruit flies, his work explores how these genes impact memory and sleep - key areas in dementia research.
@docfly.bsky.social
April 1, 2025 at 12:57 PM
bsky.app/profile/alzh... Please see our research using flies to study novel genes involved in Alzheimer's, thanks for the support BRACE
Reposted by Professor James Hodge
We @hughp.bsky.social have a 3 year postdoc in rodent circadian behaviour and ageing at University of Bristol
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
March 20, 2025 at 1:31 PM
We @hughp.bsky.social have a 3 year postdoc in rodent circadian behaviour and ageing at University of Bristol
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
We @hughp.bsky.social have a 3 year postdoc in rodent circadian behaviour and ageing at University of Bristol
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
March 20, 2025 at 1:31 PM
We @hughp.bsky.social have a 3 year postdoc in rodent circadian behaviour and ageing at University of Bristol
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
www.bristol.ac.uk/jobs/find-in...
deadline 15 April join our BBSRC sLola on CircadiAgeing: circadian rhythms, clock excitability & healthy ageing www.ukri.org/news/bbsrc-i...
Reposted by Professor James Hodge
A honey bee chimeric nAChR ion channel in Drosophila for modelling species-specific insecticide response thanks to @annalassota.bsky.social and @docfly.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Assessing species-specific neonicotinoid toxicity using cross-species chimeric nicotinic acetylcholine receptors in a Drosophila model
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels and the main mediators of synaptic neurotransmission in the insect brain. In insects, nAChRs are pivotal for sensory processing...
www.biorxiv.org
March 20, 2025 at 1:26 PM
A honey bee chimeric nAChR ion channel in Drosophila for modelling species-specific insecticide response thanks to @annalassota.bsky.social and @docfly.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Honoured that Drs Sam Amin, Thiloka Ratnaike, Qiang Liu, Bethan Vaughan and I have been awarded an EBI grant to explore the feasibility of using AI for Patient Registries
elizabethblackwellinstitute.blogs.bristol.ac.uk/2025/02/26/m...
elizabethblackwellinstitute.blogs.bristol.ac.uk/2025/02/26/m...
March 12, 2025 at 2:07 PM
Honoured that Drs Sam Amin, Thiloka Ratnaike, Qiang Liu, Bethan Vaughan and I have been awarded an EBI grant to explore the feasibility of using AI for Patient Registries
elizabethblackwellinstitute.blogs.bristol.ac.uk/2025/02/26/m...
elizabethblackwellinstitute.blogs.bristol.ac.uk/2025/02/26/m...
One week to go until my inaugural lecture at University of Bristol
February 11, 2025 at 5:12 PM
One week to go until my inaugural lecture at University of Bristol
Our @hannahrees.bsky.social @bioclocksuk.bsky.social @dynamicbrain.bsky.social @andrewmillar.bsky.social @rebeccahughes.bsky.social @antdodd.bsky.social @mvonschantz.bsky.social @roblucas.bsky.social @andrewmillar.bsky.social BioclocksUK review published
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
BioClocks UK: driving robust cycles of discovery to impact | Philosophical Transactions of the Royal Society B: Biological Sciences
Chronobiology is a multidisciplinary field that extends across the tree of life, transcends
all scales of biological organization, and has huge translational potential. For the
UK to harness the oppor...
royalsocietypublishing.org
January 30, 2025 at 6:19 PM
Announcing award of our 5 year BBSRC sLola CircadiAgeing: clock excitability, circadian rhythms & healthy ageing grant with @hughp.bsky.social @MeganGJackson @mbra3.bsky.social @krasimiratsaneva.bsky.social @mino-belle.bsky.social @alessiovagnoni.bsky.social Edgar Buhl
bristol.ac.uk/news/2024/de...
bristol.ac.uk/news/2024/de...
December 13, 2024 at 12:08 PM
Announcing award of our 5 year BBSRC sLola CircadiAgeing: clock excitability, circadian rhythms & healthy ageing grant with @hughp.bsky.social @MeganGJackson @mbra3.bsky.social @krasimiratsaneva.bsky.social @mino-belle.bsky.social @alessiovagnoni.bsky.social Edgar Buhl
bristol.ac.uk/news/2024/de...
bristol.ac.uk/news/2024/de...