Deepika Sharma
@deepika18989.bsky.social
Reposted by Deepika Sharma
Brilliant time as always at our @crgglasgow.bsky.social away day at @sceneuog.bsky.social
June 19, 2025 at 11:19 AM
Brilliant time as always at our @crgglasgow.bsky.social away day at @sceneuog.bsky.social
Reposted by Deepika Sharma
Thanks for reading! Big shout out to co-first authors @deepika18989.bsky.social, Liiya & Rhona, plus the others PIs in our Translational Neuroinflammtion Group (www.gla.ac.uk/research/az/...), particular my partner-in-crime Jonathan Cavanagh and Neil Basu. 14/
University of Glasgow - Research - Research units A-Z - Translational Neuroinflammation GroupSearch iconClose menu iconMenu icon bar 1Menu icon bar 2Menu icon bar 3
www.gla.ac.uk
June 11, 2025 at 8:46 PM
Thanks for reading! Big shout out to co-first authors @deepika18989.bsky.social, Liiya & Rhona, plus the others PIs in our Translational Neuroinflammtion Group (www.gla.ac.uk/research/az/...), particular my partner-in-crime Jonathan Cavanagh and Neil Basu. 14/
Reposted by Deepika Sharma
It's that time of the month - #NeuroSkyence #Preprint alert! A lot of our focus is on the intersection of immunology and neuroscience, and the role of neuroinflammation in brain disease. We're interested in how global inflammation has circuit-specific effects. 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Neuroinflammation driven by TLR7 activation in mice results in a global inflammatory response driving circuit-specific changes in neuronal gene expression
Interactions between the brain and immune system play a key role in the aetiology of brain disorders, with inflammation emerging as a potential causal factor in subsets of major depressive disorder, p...
www.biorxiv.org
April 29, 2025 at 11:13 AM
It's that time of the month - #NeuroSkyence #Preprint alert! A lot of our focus is on the intersection of immunology and neuroscience, and the role of neuroinflammation in brain disease. We're interested in how global inflammation has circuit-specific effects. 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Deepika Sharma
As always, this was a huge team effort, a product of close collaboration with my immunologist / psychiatrist comrade-in-arms, Jonathan Cavanagh. The study was led by Kirstyn Gardner-Stephen, with important contributions from @deepika18989.bsky.social and others not on BlueSky.
April 29, 2025 at 11:13 AM
As always, this was a huge team effort, a product of close collaboration with my immunologist / psychiatrist comrade-in-arms, Jonathan Cavanagh. The study was led by Kirstyn Gardner-Stephen, with important contributions from @deepika18989.bsky.social and others not on BlueSky.
Reposted by Deepika Sharma
We've been working hard to update this one, which I realised disappeared from my social media posts after I nuked X last autumn. tl;dr: midline thalamic input to ventral striatum get impaired in a model of inflammation #neuroskyence. And lots of immunology happens 🤣
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Anhedonic behaviour in a TLR7-driven neuroinflammation mouse model is associated with impaired thalamostriatal signalling and immune cell ingress into the brain
Depression is a heterogenous condition driven by multiple aetiologies, which make its pathophysiology challenging to map. Stratifying depression by underlying biological causes may allow for more effe...
www.biorxiv.org
February 15, 2025 at 10:43 PM
We've been working hard to update this one, which I realised disappeared from my social media posts after I nuked X last autumn. tl;dr: midline thalamic input to ventral striatum get impaired in a model of inflammation #neuroskyence. And lots of immunology happens 🤣
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Deepika Sharma
A bit of #NeuroSkyence to bring a little joy to our timelines. Magenta shows an astrocyte that's churning out lots of TNFa, and yellow is an IBA1 stain. You can see the microglia closest to the astrocyte have become reactive while those further away are more normal. Isn't science fun!?
February 25, 2025 at 11:11 AM
A bit of #NeuroSkyence to bring a little joy to our timelines. Magenta shows an astrocyte that's churning out lots of TNFa, and yellow is an IBA1 stain. You can see the microglia closest to the astrocyte have become reactive while those further away are more normal. Isn't science fun!?