Decoding Longevity
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Decoding Longevity
@decodinglongevity.bsky.social
🎙️ Decoding Longevity – Exploring the frontiers of aging science & longevity research.
🧬 Geroscience | Epigenetics | Healthspan
🎧 Listen https://open.spotify.com/episode/5PuTCbkQu3ptSQOXhQeL1P?si=JmG4ByFKQk-YFE7FXFgWaQ
Could stem cells unlock a new era of regenerative medicine? 🔬

In Episode 17 of Decoding Longevity, Yuta Lee joins Raghav Sehgal & Macsue Jacques to discuss how tapping into our body’s earliest blueprint might one day reset aging itself.
November 10, 2025 at 5:36 PM
🎧 Listen on Spotify: open.spotify.com/episode/7JCu...
📺 Watch the full episode: youtu.be/43nF-7ZKKNM?...
November 5, 2025 at 5:39 PM
What if the key to longevity lies in the earliest stem cells — ones that can rejuvenate tissues without ethical barriers? 🌿

In Ep.17 of Decoding Longevity, Yuta Lee joins Raghav Sehgal & Macsue Jacques to explore a new era of regenerative medicine.
November 5, 2025 at 5:39 PM
Tomorrow’s episode dives into one of the most exciting frontiers in longevity — regenerative medicine. 🌱

Hosts Raghav Sehgal & Macsue Jacques chat with Yuta Lee (Accelerated Biosciences) about pioneering pluripotent stem cells that could redefine aging itself.

🎧 Episode 17 out tomorrow!
November 4, 2025 at 7:33 PM
“You don’t need any of this oxidized cholesterol in your body.”

Dr. Matthew O’Connor explains how 7-ketocholesterol — a toxic, oxidized form — drives vascular aging.

🎧 Ep16 out now!
🔗 Spotify: open.spotify.com/episode/1ctI... | YouTube: youtu.be/EVhx11YavTk?...
October 31, 2025 at 5:28 PM
We’ve been treating cholesterol for decades — but 7-ketocholesterol is far more toxic than we realized.

🎧 New Decoding Longevity episode out now!
Ep16: Targeting 7-Ketocholesterol in Atherosclerosis

🔗 Spotify: open.spotify.com/episode/1ctI... | YouTube: youtu.be/EVhx11YavTk?...
October 29, 2025 at 6:29 PM
What if cardiovascular aging could be reversed? 🧬
In Episode 16 of Decoding Longevity, Matthew “Oki” O’Connor explains how targeting 7-ketocholesterol — a toxic oxidized cholesterol — might be the key to tackling atherosclerosis at its root. 🎙️
#Longevity #AgingResearch #CardiovascularHealth
October 27, 2025 at 8:54 PM
🎙️ Episode 16 is out today!

What if cardiovascular aging could actually be reversed? 🫀

In today’s episode of Decoding Longevity, Matthew “Oki” O’Connor joins Raghav Sehgal and Macsue Jacques to explore how targeting 7-ketocholesterol could reshape heart health.

#Longevity
October 22, 2025 at 5:12 PM
New episode drops tomorrow! 🎙️

Join Raghav Sehgal and Macsue Jacques in conversation with Matthew “Oki” O’Connor on how clearing 7-ketocholesterol — a toxic oxidized lipid — could reverse plaque buildup and change how we treat cardiovascular aging.

#Longevity #Atherosclerosis #HealthyAging
October 21, 2025 at 5:54 PM
“Longevity should be part of basic healthcare, not a privilege.” 🌍

In Episode 15 of Decoding Longevity, Jasmine Smith (Rejuve.AI) joins hosts Raghav Sehgal & Macsue Jacques to explore how AI and decentralized science make longevity more inclusive.

#Longevity #AI #DeSci #Healthspan
October 17, 2025 at 7:20 PM
What if the future of science wasn’t locked in labs, but built on a global network of people sharing data and accelerating discoveries in real time? 🌍
That’s the vision of decentralized science (DeSci) — and it’s transforming how we study aging and longevity.
October 10, 2025 at 8:06 PM
“Decentralized science is about breaking down silos and creating a global network where everyone can contribute to longevity research.” 🌍🧬

In Decoding Longevity Ep.15, Raghav Sehgal & Macsue Jacques explore how Rejuve.AI’s vision of DeSci is changing the way we study aging.
October 8, 2025 at 6:11 PM
October 6, 2025 at 6:19 PM
Beyond DNA: the future of aging research lies in multi-omics approaches. 🌍

In Ep.14 of Decoding Longevity, host Macsue Jacques and Prof. Brian Kennedy discuss how proteomics, lipidomics, and other biomarkers can provide a holistic view of aging.

#Longevity #HealthyAging #MultiOmics #BrianKennedy
October 6, 2025 at 6:19 PM
“Methylation clocks are powerful, but in the clinic, changing lives takes more.” 🧬

In Decoding Longevity Ep.14, Dr. Macsue Jacques and Prof. Brian Kennedy explore:
– Why methylation has limits in clinical use
– How biomarkers must evolve for real-world impact
– The future of aging diagnostics
October 1, 2025 at 4:26 PM
In Ep.14 of Decoding Longevity, Prof. Brian Kennedy and Dr. Macsue Jacques explore how integrating these tools could revolutionize aging diagnostics.

🎧 Episode available now!
🟢 open.spotify.com/episode/3UnV...
🔴 youtu.be/xNz8s1qiziI?...

#Longevity #HealthyAging #AgingResearch #EpigeneticClocks
September 29, 2025 at 6:25 PM
Every biological clock tells a different story. 🕰️

DNA methylation, proteomics, lipidomics — each has strengths, weaknesses, and unique insights into aging.
September 29, 2025 at 6:25 PM
🎧 The full episode is live now — don’t miss it!

#Longevity #EpigeneticClocks #HealthyAging
September 26, 2025 at 6:46 PM
🎙️ New episode out today!

On Decoding Longevity Ep. #14, Dr. Macsue Jacques welcomes Prof. Brian Kennedy for a fascinating discussion on:
✨ Biological aging clocks that predict mortality
✨ Why modifiable clinical features matter
✨ How science is transforming our approach to longevity
September 24, 2025 at 5:48 PM
🚨 New episode dropped! 🚨

“If we are calling ourselves aging researchers and we haven’t defined aging, I think there is a lack. We need a definition that we can operationalize.” — Prof. Andrea B. Maier, from National University of Singapore
September 15, 2025 at 5:57 PM
What if precision medicine applied not only to disease, but to aging itself? 🧬

In Ep13 of Decoding Longevity, Prof. Andrea B. Maier joins hosts Raghav Sehgal & Macsue Jacques to discuss how personalized biology could change the way we age.

#Longevity #PrecisionMedicine
September 11, 2025 at 8:22 PM
In Ep.13 of Decoding Longevity, hosts Raghav Sehgal & Macsue Jacques explore why diagnosis is key to healthy longevity medicine.

#HealthyLongevity #PrecisionGeromedicine #LongevityScience
September 10, 2025 at 5:16 PM
🚨 Our latest episode just dropped today! 🚨

“First we diagnose, then we treat. The same should apply to aging.”
— Prof. Andrea B. Maier
September 10, 2025 at 5:16 PM