Decoding Longevity
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decodinglongevity.bsky.social
Decoding Longevity
@decodinglongevity.bsky.social
🎙️ Decoding Longevity – Exploring the frontiers of aging science & longevity research.
🧬 Geroscience | Epigenetics | Healthspan
🎧 Listen https://open.spotify.com/episode/5PuTCbkQu3ptSQOXhQeL1P?si=JmG4ByFKQk-YFE7FXFgWaQ
Could stem cells unlock a new era of regenerative medicine? 🔬

In Episode 17 of Decoding Longevity, Yuta Lee joins Raghav Sehgal & Macsue Jacques to discuss how tapping into our body’s earliest blueprint might one day reset aging itself.
November 10, 2025 at 5:36 PM
What if the key to longevity lies in the earliest stem cells — ones that can rejuvenate tissues without ethical barriers? 🌿

In Ep.17 of Decoding Longevity, Yuta Lee joins Raghav Sehgal & Macsue Jacques to explore a new era of regenerative medicine.
November 5, 2025 at 5:39 PM
Tomorrow’s episode dives into one of the most exciting frontiers in longevity — regenerative medicine. 🌱

Hosts Raghav Sehgal & Macsue Jacques chat with Yuta Lee (Accelerated Biosciences) about pioneering pluripotent stem cells that could redefine aging itself.

🎧 Episode 17 out tomorrow!
November 4, 2025 at 7:33 PM
“You don’t need any of this oxidized cholesterol in your body.”

Dr. Matthew O’Connor explains how 7-ketocholesterol — a toxic, oxidized form — drives vascular aging.

🎧 Ep16 out now!
🔗 Spotify: open.spotify.com/episode/1ctI... | YouTube: youtu.be/EVhx11YavTk?...
October 31, 2025 at 5:28 PM
We’ve been treating cholesterol for decades — but 7-ketocholesterol is far more toxic than we realized.

🎧 New Decoding Longevity episode out now!
Ep16: Targeting 7-Ketocholesterol in Atherosclerosis

🔗 Spotify: open.spotify.com/episode/1ctI... | YouTube: youtu.be/EVhx11YavTk?...
October 29, 2025 at 6:29 PM
What if cardiovascular aging could be reversed? 🧬
In Episode 16 of Decoding Longevity, Matthew “Oki” O’Connor explains how targeting 7-ketocholesterol — a toxic oxidized cholesterol — might be the key to tackling atherosclerosis at its root. 🎙️
#Longevity #AgingResearch #CardiovascularHealth
October 27, 2025 at 8:54 PM
🎙️ Episode 16 is out today!

What if cardiovascular aging could actually be reversed? 🫀

In today’s episode of Decoding Longevity, Matthew “Oki” O’Connor joins Raghav Sehgal and Macsue Jacques to explore how targeting 7-ketocholesterol could reshape heart health.

#Longevity
October 22, 2025 at 5:12 PM
New episode drops tomorrow! 🎙️

Join Raghav Sehgal and Macsue Jacques in conversation with Matthew “Oki” O’Connor on how clearing 7-ketocholesterol — a toxic oxidized lipid — could reverse plaque buildup and change how we treat cardiovascular aging.

#Longevity #Atherosclerosis #HealthyAging
October 21, 2025 at 5:54 PM
“Longevity should be part of basic healthcare, not a privilege.” 🌍

In Episode 15 of Decoding Longevity, Jasmine Smith (Rejuve.AI) joins hosts Raghav Sehgal & Macsue Jacques to explore how AI and decentralized science make longevity more inclusive.

#Longevity #AI #DeSci #Healthspan
October 17, 2025 at 7:20 PM
What if the future of science wasn’t locked in labs, but built on a global network of people sharing data and accelerating discoveries in real time? 🌍
That’s the vision of decentralized science (DeSci) — and it’s transforming how we study aging and longevity.
October 10, 2025 at 8:06 PM
“Decentralized science is about breaking down silos and creating a global network where everyone can contribute to longevity research.” 🌍🧬

In Decoding Longevity Ep.15, Raghav Sehgal & Macsue Jacques explore how Rejuve.AI’s vision of DeSci is changing the way we study aging.
October 8, 2025 at 6:11 PM
Beyond DNA: the future of aging research lies in multi-omics approaches. 🌍

In Ep.14 of Decoding Longevity, host Macsue Jacques and Prof. Brian Kennedy discuss how proteomics, lipidomics, and other biomarkers can provide a holistic view of aging.

#Longevity #HealthyAging #MultiOmics #BrianKennedy
October 6, 2025 at 6:19 PM
“Methylation clocks are powerful, but in the clinic, changing lives takes more.” 🧬

In Decoding Longevity Ep.14, Dr. Macsue Jacques and Prof. Brian Kennedy explore:
– Why methylation has limits in clinical use
– How biomarkers must evolve for real-world impact
– The future of aging diagnostics
October 1, 2025 at 4:26 PM
Every biological clock tells a different story. 🕰️

DNA methylation, proteomics, lipidomics — each has strengths, weaknesses, and unique insights into aging.
September 29, 2025 at 6:25 PM
“What if we could measure how fast we’re aging—AND test if lifestyle changes could slow it down?”

In Ep. #14 of Decoding Longevity, Dr. Macsue Jacques hosts Prof. Brian Kennedy for a deep dive into epigenetic clocks, interventions, and the future of healthy aging.
September 26, 2025 at 6:46 PM
🎙️ New episode out today!

On Decoding Longevity Ep. #14, Dr. Macsue Jacques welcomes Prof. Brian Kennedy for a fascinating discussion on:
✨ Biological aging clocks that predict mortality
✨ Why modifiable clinical features matter
✨ How science is transforming our approach to longevity
September 24, 2025 at 5:48 PM
🚨 New episode dropped! 🚨

“If we are calling ourselves aging researchers and we haven’t defined aging, I think there is a lack. We need a definition that we can operationalize.” — Prof. Andrea B. Maier, from National University of Singapore
September 15, 2025 at 5:57 PM
What if precision medicine applied not only to disease, but to aging itself? 🧬

In Ep13 of Decoding Longevity, Prof. Andrea B. Maier joins hosts Raghav Sehgal & Macsue Jacques to discuss how personalized biology could change the way we age.

#Longevity #PrecisionMedicine
September 11, 2025 at 8:22 PM
🚨 Our latest episode just dropped today! 🚨

“First we diagnose, then we treat. The same should apply to aging.”
— Prof. Andrea B. Maier
September 10, 2025 at 5:16 PM
The future of aging isn’t generic—it’s precision geromedicine. 🌍✨

In Ep13 of Decoding Longevity, Prof. Andrea B. Maier (National University of Singapore) joins Raghav Sehgal & Macsue Jacques to explore how biomarkers, genetics & multi-organ data shape interventions built for your biology.
September 9, 2025 at 4:59 PM
Clocks estimate age. But what if they could reveal discoveries? 🧬

EnsembleAge detects stress, rejuvenation & novel mechanisms, helping translate aging science into clinics.

🎧 Ep. 12 of Decoding Longevity with Dr. Amin Hagani
Hosts: Raghav Sehgal & Macsue Jacques

#Longevity #AgingResearch
September 6, 2025 at 5:52 PM
🚀 New Episode!
Aging isn’t one-dimensional—it’s chemical, genetic, environmental & more. In Ep. 12, Dr. Amin Haghani joins hosts @rvsehgal.bsky.social & Macsue Jacques to share how EnsembleAge captures the full story of aging.
🎧 Listen here: open.spotify.com/episode/0U0z...
#Longevity #AgingScience
September 3, 2025 at 9:34 PM
What if we could detect subtle biological changes before symptoms appear? 🧬
August 29, 2025 at 5:11 PM
New episode out now! 🚨

In Ep.12 of Decoding Longevity, Dr. Amin Haghani joins hosts Raghav Sehgal & Macsue Jacques to discuss EnsembleAge—a new generation of epigenetic clocks reshaping how we measure aging, stress, and rejuvenation.

🎧 Watch/Listen now!

#Longevity #AgingScience #Epigenetics
August 27, 2025 at 4:28 PM
🎙️ Tomorrow we drop a new episode of Decoding Longevity!

Our guest Dr. Amin Haghani takes us inside the development of EnsembleAge and its impact on aging research. We’re grateful for his insights and can’t wait to share this conversation with you.

✨ Stay tuned — Episode 12 is almost here!
August 26, 2025 at 5:29 PM