David Usharauli
@davidusharauli.bsky.social
Immunologist & biotech startup co-founder (tregeutix.com) on a mission to harness the power of Tregs & microbiota | Calling on visionary investors to join our journey 🚀
The Weekend Tunes
JUNG HYE RIN _Melty Love(샤르르 샤르르)
(South Korea🇰🇷)
Korean trot music sounds like those songs that, when played, signaled everyone to jump up and start dancing at rural weddings in the USSR.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/G-4Oj7ztVyo?...
JUNG HYE RIN _Melty Love(샤르르 샤르르)
(South Korea🇰🇷)
Korean trot music sounds like those songs that, when played, signaled everyone to jump up and start dancing at rural weddings in the USSR.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/G-4Oj7ztVyo?...
November 8, 2025 at 9:16 PM
The Weekend Tunes
JUNG HYE RIN _Melty Love(샤르르 샤르르)
(South Korea🇰🇷)
Korean trot music sounds like those songs that, when played, signaled everyone to jump up and start dancing at rural weddings in the USSR.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/G-4Oj7ztVyo?...
JUNG HYE RIN _Melty Love(샤르르 샤르르)
(South Korea🇰🇷)
Korean trot music sounds like those songs that, when played, signaled everyone to jump up and start dancing at rural weddings in the USSR.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/G-4Oj7ztVyo?...
The Weekend Tunes
Shohruhxon & Nilufar Usmonova - Yoqasan (I Like You)
(🇺🇿 Uzbekistan)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/-z2n950Zz20?...
Shohruhxon & Nilufar Usmonova - Yoqasan (I Like You)
(🇺🇿 Uzbekistan)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/-z2n950Zz20?...
November 1, 2025 at 10:40 PM
The Weekend Tunes
Shohruhxon & Nilufar Usmonova - Yoqasan (I Like You)
(🇺🇿 Uzbekistan)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/-z2n950Zz20?...
Shohruhxon & Nilufar Usmonova - Yoqasan (I Like You)
(🇺🇿 Uzbekistan)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
youtu.be/-z2n950Zz20?...
John Glubb argued that the 7th-century rise of the Arab Empire and spread of Islam reshaped Europe by cutting off Mediterranean trade, hastening the fall of cities, and giving birth to the feudal world of the Dark Ages.
#history
#books
buff.ly/F7jDlxw
#history
#books
buff.ly/F7jDlxw
November 1, 2025 at 9:37 PM
John Glubb argued that the 7th-century rise of the Arab Empire and spread of Islam reshaped Europe by cutting off Mediterranean trade, hastening the fall of cities, and giving birth to the feudal world of the Dark Ages.
#history
#books
buff.ly/F7jDlxw
#history
#books
buff.ly/F7jDlxw
The Weekend Tunes
화사 (HWASA) - 'Good Goodbye' (🇰🇷 South Korea)
The scene in the video reminded me of the Korean TV series When Life Gives You Tangerines, while the chorus brought to mind Lady Gaga’s Bad Romance.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=Qe8f...
화사 (HWASA) - 'Good Goodbye' (🇰🇷 South Korea)
The scene in the video reminded me of the Korean TV series When Life Gives You Tangerines, while the chorus brought to mind Lady Gaga’s Bad Romance.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=Qe8f...
October 25, 2025 at 8:11 PM
The Weekend Tunes
화사 (HWASA) - 'Good Goodbye' (🇰🇷 South Korea)
The scene in the video reminded me of the Korean TV series When Life Gives You Tangerines, while the chorus brought to mind Lady Gaga’s Bad Romance.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=Qe8f...
화사 (HWASA) - 'Good Goodbye' (🇰🇷 South Korea)
The scene in the video reminded me of the Korean TV series When Life Gives You Tangerines, while the chorus brought to mind Lady Gaga’s Bad Romance.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=Qe8f...
DNA-based vaccines have yet to meet their promise, but a new Canadian preprint shows that DNA LNP vaccination induces lasting neutralizing antibodies in hamsters, overcoming a major mRNA LNP limitation. Could this mark a revival?
#mRNa
#DNA
#vaccine
buff.ly/pzgfjZh
#mRNa
#DNA
#vaccine
buff.ly/pzgfjZh
October 19, 2025 at 7:14 PM
DNA-based vaccines have yet to meet their promise, but a new Canadian preprint shows that DNA LNP vaccination induces lasting neutralizing antibodies in hamsters, overcoming a major mRNA LNP limitation. Could this mark a revival?
#mRNa
#DNA
#vaccine
buff.ly/pzgfjZh
#mRNa
#DNA
#vaccine
buff.ly/pzgfjZh
The Weekend Tunes
Ridsa - Me Enamore (🇫🇷 France)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=EI2d...
Ridsa - Me Enamore (🇫🇷 France)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=EI2d...
October 18, 2025 at 8:28 PM
The Weekend Tunes
Ridsa - Me Enamore (🇫🇷 France)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=EI2d...
Ridsa - Me Enamore (🇫🇷 France)
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=EI2d...
The Weekend Tunes
Damiano David, Tyla, Nile Rodgers - Talk to Me
(🇮🇹 Italy 🇿🇦 South Africa 🇺🇸 USA)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=PLTJ...
Damiano David, Tyla, Nile Rodgers - Talk to Me
(🇮🇹 Italy 🇿🇦 South Africa 🇺🇸 USA)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=PLTJ...
October 11, 2025 at 9:13 PM
The Weekend Tunes
Damiano David, Tyla, Nile Rodgers - Talk to Me
(🇮🇹 Italy 🇿🇦 South Africa 🇺🇸 USA)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=PLTJ...
Damiano David, Tyla, Nile Rodgers - Talk to Me
(🇮🇹 Italy 🇿🇦 South Africa 🇺🇸 USA)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=PLTJ...
The Weekend Tunes
Kalifarniya- QYLYQ (🇰🇿 Kazakhstan)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=KOOk...
Kalifarniya- QYLYQ (🇰🇿 Kazakhstan)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=KOOk...
October 3, 2025 at 11:57 PM
The Weekend Tunes
Kalifarniya- QYLYQ (🇰🇿 Kazakhstan)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=KOOk...
Kalifarniya- QYLYQ (🇰🇿 Kazakhstan)
#WorldMusic 🌍🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=KOOk...
The Weekend Tunes
FLM - Ráncok a szemem alatt (🇭🇺 Hungary)
FLM has returned after 30 years with a genuine new synthpop track.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=gydv...
FLM - Ráncok a szemem alatt (🇭🇺 Hungary)
FLM has returned after 30 years with a genuine new synthpop track.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=gydv...
September 27, 2025 at 8:36 PM
The Weekend Tunes
FLM - Ráncok a szemem alatt (🇭🇺 Hungary)
FLM has returned after 30 years with a genuine new synthpop track.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=gydv...
FLM - Ráncok a szemem alatt (🇭🇺 Hungary)
FLM has returned after 30 years with a genuine new synthpop track.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=gydv...
This form of complex decision-making in the termite nervous system approaches that of primate, or at least mammalian, brains. It illustrates how nature often reuses fundamental neural architectures rather than constructing them anew.
#science
buff.ly/21VgBVx
#science
buff.ly/21VgBVx
September 25, 2025 at 7:34 PM
This form of complex decision-making in the termite nervous system approaches that of primate, or at least mammalian, brains. It illustrates how nature often reuses fundamental neural architectures rather than constructing them anew.
#science
buff.ly/21VgBVx
#science
buff.ly/21VgBVx
"Science winnows submissions using a team of full-time professional editors" [former scientists]
This arrangement highlights a paradox of gatekeeping in #science, where editors with modest academic records decide the fate of more accomplished researchers.
buff.ly/WGL76W8
This arrangement highlights a paradox of gatekeeping in #science, where editors with modest academic records decide the fate of more accomplished researchers.
buff.ly/WGL76W8
September 23, 2025 at 6:40 PM
"Science winnows submissions using a team of full-time professional editors" [former scientists]
This arrangement highlights a paradox of gatekeeping in #science, where editors with modest academic records decide the fate of more accomplished researchers.
buff.ly/WGL76W8
This arrangement highlights a paradox of gatekeeping in #science, where editors with modest academic records decide the fate of more accomplished researchers.
buff.ly/WGL76W8
Not just ‘memory T cells act as microbial surrogates to drive innate immune activation and inflammation’, activated CD4 T cells can as well. This is precisely why only antigen-specific Tregs can keep anti-self T cell responses from spiraling out.
#Foxp3
buff.ly/hmM40L0
#Foxp3
buff.ly/hmM40L0
September 20, 2025 at 10:57 PM
Not just ‘memory T cells act as microbial surrogates to drive innate immune activation and inflammation’, activated CD4 T cells can as well. This is precisely why only antigen-specific Tregs can keep anti-self T cell responses from spiraling out.
#Foxp3
buff.ly/hmM40L0
#Foxp3
buff.ly/hmM40L0
The president announced Friday that H-1B visas will now come with a $100,000 annual fee, but a U.S. official said it will only apply to new visa applicants.
#H1B
#update
buff.ly/87a6Sm9
#H1B
#update
buff.ly/87a6Sm9
September 20, 2025 at 5:30 PM
The president announced Friday that H-1B visas will now come with a $100,000 annual fee, but a U.S. official said it will only apply to new visa applicants.
#H1B
#update
buff.ly/87a6Sm9
#H1B
#update
buff.ly/87a6Sm9
There’s a clear contradiction between the article’s title, snippet, and content. The headline claims ‘millions in grant money begin trickling back to scientists,’ but the article itself says ‘payments have not been restored.’
#science
#funding
buff.ly/gl3dssA
#science
#funding
buff.ly/gl3dssA
September 20, 2025 at 5:13 PM
There’s a clear contradiction between the article’s title, snippet, and content. The headline claims ‘millions in grant money begin trickling back to scientists,’ but the article itself says ‘payments have not been restored.’
#science
#funding
buff.ly/gl3dssA
#science
#funding
buff.ly/gl3dssA
The Weekend Tunes
Anna Vissi (Άννα Βίσση) - Sandre (Σαντρέ) - Dirty Blond
(🇬🇷 Greece)
Second time I’m picking an #AnnaVissi song for best #popsong of the week of randomly listened songs.
Absolute fire 🔥
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=6gP_...
Anna Vissi (Άννα Βίσση) - Sandre (Σαντρέ) - Dirty Blond
(🇬🇷 Greece)
Second time I’m picking an #AnnaVissi song for best #popsong of the week of randomly listened songs.
Absolute fire 🔥
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=6gP_...
September 19, 2025 at 11:45 PM
The Weekend Tunes
Anna Vissi (Άννα Βίσση) - Sandre (Σαντρέ) - Dirty Blond
(🇬🇷 Greece)
Second time I’m picking an #AnnaVissi song for best #popsong of the week of randomly listened songs.
Absolute fire 🔥
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=6gP_...
Anna Vissi (Άννα Βίσση) - Sandre (Σαντρέ) - Dirty Blond
(🇬🇷 Greece)
Second time I’m picking an #AnnaVissi song for best #popsong of the week of randomly listened songs.
Absolute fire 🔥
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=6gP_...
Reading this @Nature piece, it really is just the old proverb: he who pays the piper calls the tune. When is asymmetrical power ever given up voluntarily? At the very least, it requires seeing others as extensions of self, not as foreign.
#society
buff.ly/X2wbqbg
#society
buff.ly/X2wbqbg
September 16, 2025 at 6:48 PM
Reading this @Nature piece, it really is just the old proverb: he who pays the piper calls the tune. When is asymmetrical power ever given up voluntarily? At the very least, it requires seeing others as extensions of self, not as foreign.
#society
buff.ly/X2wbqbg
#society
buff.ly/X2wbqbg
The Atlantic: AI Executives Promise Cancer Cures. Here’s the Reality
#AI
#biology
#science
buff.ly/QMeKa7d
#AI
#biology
#science
buff.ly/QMeKa7d
September 15, 2025 at 11:46 PM
The Atlantic: AI Executives Promise Cancer Cures. Here’s the Reality
#AI
#biology
#science
buff.ly/QMeKa7d
#AI
#biology
#science
buff.ly/QMeKa7d
NYT: Trump Is Shutting Down the War On Cancer
#science
#NIH
#cancer
#immunotherapy
#grants
t.co/GQPWmp7Lvj
#science
#NIH
#cancer
#immunotherapy
#grants
t.co/GQPWmp7Lvj
September 15, 2025 at 11:31 PM
NYT: Trump Is Shutting Down the War On Cancer
#science
#NIH
#cancer
#immunotherapy
#grants
t.co/GQPWmp7Lvj
#science
#NIH
#cancer
#immunotherapy
#grants
t.co/GQPWmp7Lvj
Yasmin Belkaid's lab reports that endogenous retroviral elements promote oral tolerance. Yet their germ-free mouse experiment conflicts with prior evidence that oral tolerance does not occur in such conditions. This needs clarification in the discussion.
@belkaidlab.bsky.social
buff.ly/cS4RK17
@belkaidlab.bsky.social
buff.ly/cS4RK17
September 13, 2025 at 7:09 PM
Yasmin Belkaid's lab reports that endogenous retroviral elements promote oral tolerance. Yet their germ-free mouse experiment conflicts with prior evidence that oral tolerance does not occur in such conditions. This needs clarification in the discussion.
@belkaidlab.bsky.social
buff.ly/cS4RK17
@belkaidlab.bsky.social
buff.ly/cS4RK17
The Weekend Tunes
Martynas Kavaliauskas - Ant Debesų (🇱🇹 Lithuania)
#Lithuanian pop has a unique melodic quality.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=RuHK...
Martynas Kavaliauskas - Ant Debesų (🇱🇹 Lithuania)
#Lithuanian pop has a unique melodic quality.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=RuHK...
September 12, 2025 at 11:57 PM
The Weekend Tunes
Martynas Kavaliauskas - Ant Debesų (🇱🇹 Lithuania)
#Lithuanian pop has a unique melodic quality.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=RuHK...
Martynas Kavaliauskas - Ant Debesų (🇱🇹 Lithuania)
#Lithuanian pop has a unique melodic quality.
#WorldMusic 🌍 🎧
#MusicUnites ❤️🎵
www.youtube.com/watch?v=RuHK...
Nice overview by Simon Fillatreau et al. on antigen-specific Treg development. But they miss the point: saying high funtional affinity thymocytes become Tregs and low-affinity become Tconv. Who gets deleted then? Weren’t those high-affinity clones?
buff.ly/cGPglCS
buff.ly/cGPglCS
September 12, 2025 at 8:23 PM
Nice overview by Simon Fillatreau et al. on antigen-specific Treg development. But they miss the point: saying high funtional affinity thymocytes become Tregs and low-affinity become Tconv. Who gets deleted then? Weren’t those high-affinity clones?
buff.ly/cGPglCS
buff.ly/cGPglCS
1/ This “working model” of Treg suppression (Shevach et al., 2006) has dominated immunology for 25+ years with little scrutiny. It proposes that Foxp3⁺ Tregs suppress T cells in an antigen-non-specific manner:a Treg specific for A can suppress T cells specific for B.
#immunology
#immunology
September 9, 2025 at 10:05 PM
1/ This “working model” of Treg suppression (Shevach et al., 2006) has dominated immunology for 25+ years with little scrutiny. It proposes that Foxp3⁺ Tregs suppress T cells in an antigen-non-specific manner:a Treg specific for A can suppress T cells specific for B.
#immunology
#immunology
The Weekend Tunes
IVE(아이브) 'XOXZ' (🇰🇷 South Korea)
STUDIO CHOOM ORIGINAL
IVE has the best songwriters in K-pop right now.
#Kpop
#WorldMusic 🌍 🎧
#MusicUnites ❤️ 🎵
youtu.be/Te78AQ4OY0w?...
IVE(아이브) 'XOXZ' (🇰🇷 South Korea)
STUDIO CHOOM ORIGINAL
IVE has the best songwriters in K-pop right now.
#Kpop
#WorldMusic 🌍 🎧
#MusicUnites ❤️ 🎵
youtu.be/Te78AQ4OY0w?...
September 6, 2025 at 12:07 AM
The Weekend Tunes
IVE(아이브) 'XOXZ' (🇰🇷 South Korea)
STUDIO CHOOM ORIGINAL
IVE has the best songwriters in K-pop right now.
#Kpop
#WorldMusic 🌍 🎧
#MusicUnites ❤️ 🎵
youtu.be/Te78AQ4OY0w?...
IVE(아이브) 'XOXZ' (🇰🇷 South Korea)
STUDIO CHOOM ORIGINAL
IVE has the best songwriters in K-pop right now.
#Kpop
#WorldMusic 🌍 🎧
#MusicUnites ❤️ 🎵
youtu.be/Te78AQ4OY0w?...
At the heart of Afghan self-understanding is the belief they preserve Islam in its purest form even though few can read Arabic. This conviction gives Islam unique legitimacy as the foundation of law and political authority.
#afghanistan
#history
buff.ly/Jt3M5mv
#afghanistan
#history
buff.ly/Jt3M5mv
September 5, 2025 at 10:15 PM
At the heart of Afghan self-understanding is the belief they preserve Islam in its purest form even though few can read Arabic. This conviction gives Islam unique legitimacy as the foundation of law and political authority.
#afghanistan
#history
buff.ly/Jt3M5mv
#afghanistan
#history
buff.ly/Jt3M5mv
News/Views: Studies deliver new blow to cancer microbiome literature—and offer a way forward
#science
#microbiome
#cancer
buff.ly/P3pGFWh
#science
#microbiome
#cancer
buff.ly/P3pGFWh
September 3, 2025 at 10:17 PM
News/Views: Studies deliver new blow to cancer microbiome literature—and offer a way forward
#science
#microbiome
#cancer
buff.ly/P3pGFWh
#science
#microbiome
#cancer
buff.ly/P3pGFWh