David Aguilera Alonso
@davidaguileraal.bsky.social
Pediatric Infectious Diseases. Antimicrobial Stewardship. Researcher and Clinician. Gregorio Marañón Hospital. Opinions mine
Reposted by David Aguilera Alonso
Treatment with #ceftolozane–tazobactam resulted in higher rates of clinical success compared with ceftazidime–avibactam for invasive infections due to multidrug-resistant P aeruginosa.
👇
www.thelancet.com/journals/lan...
#IDSky #medEd
👇
www.thelancet.com/journals/lan...
#IDSky #medEd
Effectiveness of ceftazidime–avibactam versus ceftolozane–tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the USA (CACTUS): a multicentre, retrospective, observational study
Treatment with ceftolozane–tazobactam resulted in higher rates of clinical success compared with ceftazidime–avibactam for invasive infections due to multidrug-resistant P aeruginosa. Differences were driven by improved response rates for patients with pneumonia who were treated with ceftolozane–tazobactam. There were no significant differences between study groups with respect to all-cause mortality; treatment-emergent resistance was common with both agents.
www.thelancet.com
December 21, 2024 at 4:34 PM
Treatment with #ceftolozane–tazobactam resulted in higher rates of clinical success compared with ceftazidime–avibactam for invasive infections due to multidrug-resistant P aeruginosa.
👇
www.thelancet.com/journals/lan...
#IDSky #medEd
👇
www.thelancet.com/journals/lan...
#IDSky #medEd
Reposted by David Aguilera Alonso
#Outbreak of paediatric acute #myocarditis associated with #parvovirus B19 infection in #Italy (32 cases in 2024)
The rise in cases coincides with an increase of B19V activity in the USA as well as in Europe, where a B19V outbreak appears to be ongoing.
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doi.org/10.2807/1560...
The rise in cases coincides with an increase of B19V activity in the USA as well as in Europe, where a B19V outbreak appears to be ongoing.
👇
doi.org/10.2807/1560...
Outbreak of paediatric myocarditis associated with parvovirus B19 infection in Italy, January to October 2024
Acute myocarditis has risen among paediatric patients in Italy, with 65 clinically suspected cases reported by 12 centres in 2024, 32 linked to parvovirus B19 (B19V) infection. In 11 cases, B19V was n...
doi.org
December 7, 2024 at 7:51 AM
#Outbreak of paediatric acute #myocarditis associated with #parvovirus B19 infection in #Italy (32 cases in 2024)
The rise in cases coincides with an increase of B19V activity in the USA as well as in Europe, where a B19V outbreak appears to be ongoing.
👇
doi.org/10.2807/1560...
The rise in cases coincides with an increase of B19V activity in the USA as well as in Europe, where a B19V outbreak appears to be ongoing.
👇
doi.org/10.2807/1560...
Reposted by David Aguilera Alonso
🔥🔥 NEW 🔥🔥
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...
Year In Review: Top Infectious Diseases Articles From 2024
In this article a selection of notable peer-reviewed publications from 2024 are provided. Article Selection by: Bassam Ghanem, Pharm.D., MS, BCPS Article Construction by: Timothy P. Gauthier, Pharm.D....
www.idstewardship.com
December 11, 2024 at 11:47 PM
🔥🔥 NEW 🔥🔥
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...
Reposted by David Aguilera Alonso
🆕🔥ROAD Study🔥🆕
Resistance Optimised Antibiotic Dosing
A pilot study by Prof.Jason Roberts #cmicomm
Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? #idsky #medsky
www.sciencedirect.com/science/arti...
Resistance Optimised Antibiotic Dosing
A pilot study by Prof.Jason Roberts #cmicomm
Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? #idsky #medsky
www.sciencedirect.com/science/arti...
Resistance Optimised Antibiotic Dosing (The ROAD Study): Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? A ...
Pre-clinical data suggest that resistance to beta-lactam antibiotics can be suppressed with higher than conventional antibiotic exposures. The objecti…
www.sciencedirect.com
November 27, 2024 at 8:42 AM
🆕🔥ROAD Study🔥🆕
Resistance Optimised Antibiotic Dosing
A pilot study by Prof.Jason Roberts #cmicomm
Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? #idsky #medsky
www.sciencedirect.com/science/arti...
Resistance Optimised Antibiotic Dosing
A pilot study by Prof.Jason Roberts #cmicomm
Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? #idsky #medsky
www.sciencedirect.com/science/arti...
Reposted by David Aguilera Alonso
A thorough guideline for a common consult question - one for the reference folder! #IDSky
UK guidelines for the investigation and management of eosinophilia in returning travellers and migrants
Eosinophilia is a common finding in returning travellers, migrants and other travelling
groups. In this setting it often indicates an underlying helminth infection. Infections
associated with eosinoph...
www.journalofinfection.com
November 24, 2024 at 9:09 AM
A thorough guideline for a common consult question - one for the reference folder! #IDSky
Reposted by David Aguilera Alonso
Recent Systematic Review & Meta,May 2024
6 retros N:1746
Short Vs.Prolonged Duration of Therapy for Pseudomonas aeruginosa Bacteremia
No sig # in 30d mortality
Ongoing RCTs:
SHORTEN-2👇
OPTIMISE
Just released:BALANCE 7d NI 14d[~5%PSA]
#idsky #medsky
www.journalofhospitalinfection.com/article/S019...
6 retros N:1746
Short Vs.Prolonged Duration of Therapy for Pseudomonas aeruginosa Bacteremia
No sig # in 30d mortality
Ongoing RCTs:
SHORTEN-2👇
OPTIMISE
Just released:BALANCE 7d NI 14d[~5%PSA]
#idsky #medsky
www.journalofhospitalinfection.com/article/S019...
November 21, 2024 at 7:08 PM
Recent Systematic Review & Meta,May 2024
6 retros N:1746
Short Vs.Prolonged Duration of Therapy for Pseudomonas aeruginosa Bacteremia
No sig # in 30d mortality
Ongoing RCTs:
SHORTEN-2👇
OPTIMISE
Just released:BALANCE 7d NI 14d[~5%PSA]
#idsky #medsky
www.journalofhospitalinfection.com/article/S019...
6 retros N:1746
Short Vs.Prolonged Duration of Therapy for Pseudomonas aeruginosa Bacteremia
No sig # in 30d mortality
Ongoing RCTs:
SHORTEN-2👇
OPTIMISE
Just released:BALANCE 7d NI 14d[~5%PSA]
#idsky #medsky
www.journalofhospitalinfection.com/article/S019...
Reposted by David Aguilera Alonso
#ShorterIsBetter in immunocompromised hosts?
Short treatments are feasible in early responders without source control issues.
A significant number of observational studies serve as proof-of-concept on the feasibility of short courses in selected patients (see ⚠️)
#AMSsky #IDOnc #TxID #IDsky
Short treatments are feasible in early responders without source control issues.
A significant number of observational studies serve as proof-of-concept on the feasibility of short courses in selected patients (see ⚠️)
#AMSsky #IDOnc #TxID #IDsky
November 19, 2024 at 7:05 PM
#ShorterIsBetter in immunocompromised hosts?
Short treatments are feasible in early responders without source control issues.
A significant number of observational studies serve as proof-of-concept on the feasibility of short courses in selected patients (see ⚠️)
#AMSsky #IDOnc #TxID #IDsky
Short treatments are feasible in early responders without source control issues.
A significant number of observational studies serve as proof-of-concept on the feasibility of short courses in selected patients (see ⚠️)
#AMSsky #IDOnc #TxID #IDsky
Reposted by David Aguilera Alonso
Reexamining the Role of Pyuria in UTI Diagnosis
🆕️⚡️⚡️Study
For febrile children <36 months undergoing bladder cath for suspected UTI,pyuria will be absent in ∼20% of children who are eventually shown to have pure growth of a pathogen on a culture #idsky #medsky
publications.aap.org/pediatrics/a...
🆕️⚡️⚡️Study
For febrile children <36 months undergoing bladder cath for suspected UTI,pyuria will be absent in ∼20% of children who are eventually shown to have pure growth of a pathogen on a culture #idsky #medsky
publications.aap.org/pediatrics/a...
Accuracy of Screening Tests for the Diagnosis of Urinary Tract Infections in Young Children
10.1542/6361838720112Video AbstractPEDS-VA_2024-0666006361838720112BACKGROUND:. The objective of this study was to compare the accuracy of available tests for pyuria, including newer automated tests, ...
publications.aap.org
November 21, 2024 at 7:49 PM
Reexamining the Role of Pyuria in UTI Diagnosis
🆕️⚡️⚡️Study
For febrile children <36 months undergoing bladder cath for suspected UTI,pyuria will be absent in ∼20% of children who are eventually shown to have pure growth of a pathogen on a culture #idsky #medsky
publications.aap.org/pediatrics/a...
🆕️⚡️⚡️Study
For febrile children <36 months undergoing bladder cath for suspected UTI,pyuria will be absent in ∼20% of children who are eventually shown to have pure growth of a pathogen on a culture #idsky #medsky
publications.aap.org/pediatrics/a...