Biotech Chick
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cthbiotech.bsky.social
Biotech Chick
@cthbiotech.bsky.social
Trying to make the world better through science and logical thought.
Manufacturing CMC issues trip up another promising drug. Just a reminder that even when the science and clinical data is sound, the drug still needs to be made. www.fiercepharma.com/pharma/fda-r...
www.fiercepharma.com
December 17, 2024 at 4:49 PM
Reposted by Biotech Chick
💔
‘No Way To Prevent This,’ Says Only Nation Where This Regularly Happens theonion.com/no-way-to-pr...
December 17, 2024 at 8:07 AM
So basically, fluoridation decreases dental decay - something we have already known for decades and taken for granted.
apple.news/A9A4m8IqjRBC...
This city took fluoride out of the water. Now it’s putting it back in — The Times and The Sunday Times
Rarely do politicians admit to getting it wrong. Gian-Carlo Carra, however, is an exception. Given the choice again, the Canadian councillor would not have voted to stop putting fluoride in his city’s...
apple.news
December 8, 2024 at 8:04 PM
Reposted by Biotech Chick
#OnThisDay, 28 Nov 1967, Jocelyn Bell Burnell discovers the existence of pulsars - a new type of star.

#WomenInHistory #OTD #History #WomensHistory #WomenInSTEM 🗃️

1/2
November 28, 2024 at 12:59 PM
Reposted by Biotech Chick
Today is a great day to start or get back into 99% Invisible. It's a show about the objects and systems we design and what these things say about us and our values.

Start with any episode! Jump around! Pick one about something you're into. Find one about something you're not

99percentinvisible.org
99% Invisible
99% Invisible with Roman Mars is a tiny radio show about design, architecture & the ninety-nine percent invisible activity that shapes our world.
99percentinvisible.org
November 23, 2024 at 8:00 PM
Reposted by Biotech Chick
It is a reminder that NIH is, at its heart, a collection of dedicated humans - scientists, physicians and staff - all public servants trying their best to advocate for and support the rest of us 🇺🇸
November 23, 2024 at 3:52 PM
External “efficiency” consultants are usually very good at reinforcing management biases rather than making real improvements.
November 20, 2024 at 1:11 AM
Reposted by Biotech Chick
The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/
November 16, 2024 at 3:19 PM
Reposted by Biotech Chick
The H5N1 sequence found in the hospitalized teenager shows two important mutations that improve the virus's ability to bind to human α2,6 sialic acid receptors.

This adaptation is crucial for the virus's potential to spread between humans.

The virus is evolving.

#H5N1
November 16, 2024 at 6:39 PM
On average it takes several hundred candidates and $1 b dollars to get one drug to market.
The issue here is not FDA efficiency, but the efficiency of drug discovery.
pub.mdpi-res.com/ijms/ijms-23...
November 15, 2024 at 7:30 PM
This is concerning, especially with the incoming administration’s track record of pandemic response.

www.livescience.com/health/flu/c...
Canada reports 1st local case of H5 bird flu
A teen in Canada may be the first person to catch an H5 bird flu virus within the country. Health officials are now working to confirm the diagnosis.
www.livescience.com
November 14, 2024 at 3:19 PM
www.fiercebiotech.com/biotech/hidd...
Ah, those hidden excel tabs. Not to mention a 4% bone density loss over 12 weeks is alarming.
Hidden data on obesity prospect wipe $12B off Amgen market cap
A hidden tab in an Excel spreadsheet published nine months ago has wiped $12 billion off Amgen’s market cap. | A hidden tab in an Excel spreadsheet published nine months ago has wiped $12 billion off ...
www.fiercebiotech.com
November 13, 2024 at 7:56 PM
Here it goes…. Hopefully this is the last one I join.
November 13, 2024 at 7:54 PM