@crbeuzon.bsky.social
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Congrats Alvaro (and supervisors)!
October 9, 2025 at 11:03 AM
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Fantastic talk indeed!
October 31, 2025 at 4:41 PM
Congrats to you all! Great work!!
October 9, 2025 at 11:05 AM
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Response to “The action of Arabidopsis DICER-LIKE2 in plant growth inhibition”
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...
Validate User
doi.org
October 1, 2025 at 9:09 AM
It was a pleasure to collaborate in this work!!!
September 12, 2025 at 1:49 PM
Wholeheartedly recommended ☺️
September 3, 2025 at 4:09 PM
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Very interesting...we are looking at GRFs ourselves...
September 2, 2025 at 12:23 PM
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Thank you, Jose!
September 2, 2025 at 12:26 PM
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By uncovering how RipAV hijacks the regulatory mechanism PUB-CPK28, and reduces BIK1 accumulation, our work reveals a sophisticated strategy of immune suppression. I would like to thank
@albertopmacho.bsky.social
and all collaborators!
@type3lab.bsky.social

@ihsmumacsic.bsky.social
September 2, 2025 at 7:58 AM
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This mechanism is not just incidental: we show that RipAV is required to keep BIK1 levels low during infection. Dampening BIK1 is a common virulence strategy in R. solanacearum — RipAC also reduces BIK1 levels via PUB4.
www.embopress.org/doi/full/10....
The Arabidopsis E3 ubiquitin ligase PUB4 regulates BIK1 and is targeted by a bacterial type‐III effector | The EMBO Journal
image image The soil‐borne bacterial pathogen Ralstonia solanacearum secretes an effector protein, RipAC, which suppresses plant immunity. Here, RipAC is shown to hijack the dynamic regulation of plant pattern‐triggered immunity by ...
www.embopress.org
September 2, 2025 at 7:58 AM
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This modification promotes the proteasome-mediated degradation of BIK1, a core immune component required for pattern-triggered immunity. In other words, RipAV accelerates the removal of one of the plant’s most important defense proteins.
September 2, 2025 at 7:58 AM
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RipAV promotes phosphorylation of PUBs by CPK28 on a specific Thr site. This post-translational modification boosts PUB25/26 activity, as previously shown by Wang et al. (2018).
www.sciencedirect.com/science/arti...
A Regulatory Module Controlling Homeostasis of a Plant Immune Kinase
Plant pattern recognition receptors (PRRs) perceive microbial and endogenous molecular patterns to activate immune signaling. The cytoplasmic kinase B…
www.sciencedirect.com
September 2, 2025 at 7:58 AM
Reposted
Ralstonia solanacearum causes bacterial wilt, a devastating disease in many crops. We found that its effector RipAV directly interacts with plant ubiquitin ligases (PUBs) and the kinase CPK28, both central regulators of immune signaling.
September 2, 2025 at 7:58 AM
Gracias! ❤️
August 4, 2025 at 1:06 PM
Well deserved! Great things to come of it for sure!
July 31, 2025 at 8:33 AM