@crbeuzon.bsky.social
Reposted
Congrats Alvaro (and supervisors)!
October 9, 2025 at 11:03 AM
Congrats Alvaro (and supervisors)!
Reposted
Fantastic talk indeed!
October 31, 2025 at 4:41 PM
Fantastic talk indeed!
Congrats to you all! Great work!!
October 9, 2025 at 11:05 AM
Congrats to you all! Great work!!
Reposted
Response to “The action of Arabidopsis DICER-LIKE2 in plant growth inhibition”
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...
Validate User
doi.org
October 1, 2025 at 9:09 AM
Response to “The action of Arabidopsis DICER-LIKE2 in plant growth inhibition”
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...
It was a pleasure to collaborate in this work!!!
September 12, 2025 at 1:49 PM
It was a pleasure to collaborate in this work!!!
Wholeheartedly recommended ☺️
September 3, 2025 at 4:09 PM
Wholeheartedly recommended ☺️
Reposted
Very interesting...we are looking at GRFs ourselves...
September 2, 2025 at 12:23 PM
Very interesting...we are looking at GRFs ourselves...
Reposted
Thank you, Jose!
September 2, 2025 at 12:26 PM
Thank you, Jose!
Reposted
By uncovering how RipAV hijacks the regulatory mechanism PUB-CPK28, and reduces BIK1 accumulation, our work reveals a sophisticated strategy of immune suppression. I would like to thank
@albertopmacho.bsky.social
and all collaborators!
@type3lab.bsky.social
@ihsmumacsic.bsky.social
@albertopmacho.bsky.social
and all collaborators!
@type3lab.bsky.social
@ihsmumacsic.bsky.social
September 2, 2025 at 7:58 AM
By uncovering how RipAV hijacks the regulatory mechanism PUB-CPK28, and reduces BIK1 accumulation, our work reveals a sophisticated strategy of immune suppression. I would like to thank
@albertopmacho.bsky.social
and all collaborators!
@type3lab.bsky.social
@ihsmumacsic.bsky.social
@albertopmacho.bsky.social
and all collaborators!
@type3lab.bsky.social
@ihsmumacsic.bsky.social
Reposted
This mechanism is not just incidental: we show that RipAV is required to keep BIK1 levels low during infection. Dampening BIK1 is a common virulence strategy in R. solanacearum — RipAC also reduces BIK1 levels via PUB4.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
The Arabidopsis E3 ubiquitin ligase PUB4 regulates BIK1 and is targeted by a bacterial type‐III effector | The EMBO Journal
image image The soil‐borne bacterial pathogen Ralstonia solanacearum secretes an effector protein, RipAC, which suppresses plant immunity. Here, RipAC is shown to hijack the dynamic regulation of plant pattern‐triggered immunity by ...
www.embopress.org
September 2, 2025 at 7:58 AM
This mechanism is not just incidental: we show that RipAV is required to keep BIK1 levels low during infection. Dampening BIK1 is a common virulence strategy in R. solanacearum — RipAC also reduces BIK1 levels via PUB4.
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Reposted
This modification promotes the proteasome-mediated degradation of BIK1, a core immune component required for pattern-triggered immunity. In other words, RipAV accelerates the removal of one of the plant’s most important defense proteins.
September 2, 2025 at 7:58 AM
This modification promotes the proteasome-mediated degradation of BIK1, a core immune component required for pattern-triggered immunity. In other words, RipAV accelerates the removal of one of the plant’s most important defense proteins.
Reposted
RipAV promotes phosphorylation of PUBs by CPK28 on a specific Thr site. This post-translational modification boosts PUB25/26 activity, as previously shown by Wang et al. (2018).
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
A Regulatory Module Controlling Homeostasis of a Plant Immune Kinase
Plant pattern recognition receptors (PRRs) perceive microbial and endogenous molecular patterns to activate immune signaling. The cytoplasmic kinase B…
www.sciencedirect.com
September 2, 2025 at 7:58 AM
RipAV promotes phosphorylation of PUBs by CPK28 on a specific Thr site. This post-translational modification boosts PUB25/26 activity, as previously shown by Wang et al. (2018).
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted
Ralstonia solanacearum causes bacterial wilt, a devastating disease in many crops. We found that its effector RipAV directly interacts with plant ubiquitin ligases (PUBs) and the kinase CPK28, both central regulators of immune signaling.
September 2, 2025 at 7:58 AM
Ralstonia solanacearum causes bacterial wilt, a devastating disease in many crops. We found that its effector RipAV directly interacts with plant ubiquitin ligases (PUBs) and the kinase CPK28, both central regulators of immune signaling.
Well deserved! Great things to come of it for sure!
July 31, 2025 at 8:33 AM
Well deserved! Great things to come of it for sure!