@crbeuzon.bsky.social
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Congrats Alvaro (and supervisors)!
October 9, 2025 at 11:03 AM
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Fantastic talk indeed!
October 31, 2025 at 4:41 PM
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Fantastic talk by Hervé Vaucheret as part of #IHSMLaMayoraSeminars series.

Hervé presented new unpublished results on how gene silencing is triggered in plants, and left us with a clear take-home message: be careful with what you conclude based on CRISPR and transgenic lines!
October 31, 2025 at 12:48 PM
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Congratulations to the new Doctor in the lab, Álvaro Jiménez-Jiménez. Fantastic defense work!! 🧑‍🎓🥳
October 9, 2025 at 9:02 AM
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Response to “The action of Arabidopsis DICER-LIKE2 in plant growth inhibition”
The Plant Cell (@theplantcell.bsky.social)
👉 doi.org/10.1093/plce...
Validate User
doi.org
October 1, 2025 at 9:09 AM
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We’re filming our new institutional video at IHSM Mayora! 🎥🌱🎬

We’ll post it on our website (www.ihsm.uma-csic.es) as soon as it’s ready; stay tuned!
October 1, 2025 at 12:35 PM
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📢 IHSM La Mayora – New Publications!
We are pleased to share in this thread the eight scientific contributions from researchers at IHSM La Mayora published in September.

🔬 Stay tuned for more updates on our research and collaborations.
October 1, 2025 at 9:09 AM
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We are hiring a PhD student (FPI) for the
🧬🌱Plant Epitranscriptomics Lab 🧬🌱
at IHSM La Mayora (UMA-CSIC) ‪@ihsmumacsic.bsky.social‬‬
to study the role of m6A in axillary bud dormancy

Candidates send CV and motivation letter to:
✉️laura.arribas@csic.es
📆 until Sep 30th
September 3, 2025 at 3:46 PM
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Very interesting...we are looking at GRFs ourselves...
September 2, 2025 at 12:23 PM
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Thank you, Jose!
September 2, 2025 at 12:26 PM
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Very proud of this collaboration with Jose and Alberto, the co-corresponding authors; and of course, many congratulations to the Team.
#MicroSky #PlantScience
September 2, 2025 at 8:09 AM
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By uncovering how RipAV hijacks the regulatory mechanism PUB-CPK28, and reduces BIK1 accumulation, our work reveals a sophisticated strategy of immune suppression. I would like to thank
@albertopmacho.bsky.social
and all collaborators!
@type3lab.bsky.social

@ihsmumacsic.bsky.social
September 2, 2025 at 7:58 AM
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This mechanism is not just incidental: we show that RipAV is required to keep BIK1 levels low during infection. Dampening BIK1 is a common virulence strategy in R. solanacearum — RipAC also reduces BIK1 levels via PUB4.
www.embopress.org/doi/full/10....
The Arabidopsis E3 ubiquitin ligase PUB4 regulates BIK1 and is targeted by a bacterial type‐III effector | The EMBO Journal
image image The soil‐borne bacterial pathogen Ralstonia solanacearum secretes an effector protein, RipAC, which suppresses plant immunity. Here, RipAC is shown to hijack the dynamic regulation of plant pattern‐triggered immunity by ...
www.embopress.org
September 2, 2025 at 7:58 AM
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This modification promotes the proteasome-mediated degradation of BIK1, a core immune component required for pattern-triggered immunity. In other words, RipAV accelerates the removal of one of the plant’s most important defense proteins.
September 2, 2025 at 7:58 AM
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RipAV promotes phosphorylation of PUBs by CPK28 on a specific Thr site. This post-translational modification boosts PUB25/26 activity, as previously shown by Wang et al. (2018).
www.sciencedirect.com/science/arti...
A Regulatory Module Controlling Homeostasis of a Plant Immune Kinase
Plant pattern recognition receptors (PRRs) perceive microbial and endogenous molecular patterns to activate immune signaling. The cytoplasmic kinase B…
www.sciencedirect.com
September 2, 2025 at 7:58 AM
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Ralstonia solanacearum causes bacterial wilt, a devastating disease in many crops. We found that its effector RipAV directly interacts with plant ubiquitin ligases (PUBs) and the kinase CPK28, both central regulators of immune signaling.
September 2, 2025 at 7:58 AM
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Our new paper is out in New Phytologist! We describe how the Ralstonia solanacearum effector RipAV suppresses plant immunity by directly interfering with key defense regulators. 🧵👇
nph.onlinelibrary.wiley.com/doi/10.1111/...
The Ralstonia solanacearum effector RipAV targets plant U‐box proteins and induces proteasomal‐dependent degradation of BIK1
Plants have developed a complex immune system to detect and respond to invading pathogens. A critical aspect of this defense relies on regulatory mechanisms that control the activation of immune res...
nph.onlinelibrary.wiley.com
September 2, 2025 at 7:58 AM
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Introducing the 1,000 Flower Collection 🧬🌹

I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes.

Here’s how I’m making it happen… and how you can join me on this journey 🧵(1/7)
August 11, 2025 at 6:54 PM
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🎉 Thrilled to announce that CoBEPP — Using conserved bacterial effectors to probe plant-pathogen interactions — has been funded by @ageinves.bsky.social & @cienciagob.bsky.social!
Grateful for the support to launch my first project @ihsmumacsic.bsky.social , exploring effector functions! 🌱🔬
July 30, 2025 at 6:03 PM
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Slowly cleaning out my office to prepare for retirement. Of all of the documents and various printed stuff I have accumulated over the years that I am sending to recycling, why is it so difficult to get rid of the lab books and computer printouts from my PhD thesis 40 yrs ago?
July 30, 2025 at 8:15 AM
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Congrats!!!!🍾
July 30, 2025 at 11:54 AM
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The collaboration was established on the basis of our common interests in molecular mechanisms of plant defence and it's self-regulation via miRNAs

doi.org/10.1093/jxb/...
miR825-5p targets the TIR-NBS-LRR gene MIST1 and down-regulates basal immunity against Pseudomonas syringae in Arabidopsis
miR825-5p down-regulates immunity against Pseudomonas syringae and mediates cleavage of the sequence encoding the conserved motif within the MIST1 Toll/int
doi.org
July 30, 2025 at 11:55 AM
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This was a very pleasant collaboration! We wish the very best to Isabel on her retirement at the end of July: it has been an honour to collaborate with you and your team!
July 30, 2025 at 11:43 AM
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And now for something completely different!

Very proud to have contributed to this work on molecular plant-pest interaction led by Isabel Diaz Rodriguez at CBGP

doi.org/10.1111/nph....

@cbgpmadrid.bsky.social
@ihsmumacsic.bsky.social
#PlantScience
miR825‐5p‐regulated TNLs govern Arabidopsis resistance to Tetranychus urticae and Pieris brassicae
MicroRNAs are essential regulators in plant resistance to biotic stresses, but their specific roles in the plant–herbivore context require deeper investigation. Here, we studied how the Arabidopsis .....
doi.org
July 30, 2025 at 11:43 AM