Cell Host & Microbe
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Cell Host & Microbe
@cp-cellhostmicrobe.bsky.social
The scientific editors of Cell Host & Microbe, a Cell Press journal, bring you the latest information and insights from the forefront of host-microbe research.
Our October issue is live—rooted in strong microbiology and growing insights.

With cover art highlighting the gut-brain axis and work from @katesadlerphd.bsky.social
www.cell.com/cell-host-mi...
October 8, 2025 at 3:49 PM
Molecular mechanisms of host-microbiome interactions:

We teamed up w/ @cp-cellchembiol.bsky.social for a Collection of articles uncovering mechanisms by which microbes communicate w/their hosts, shedding light on various conditions & offering therapeutic avenues.Enjoy!
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October 7, 2025 at 7:15 PM
The September issue is now live with new findings on Shigella, Cryptosporidium, Lassa virus, Bifidobacterium and more!

This month’s cover features Veillonella clearing a path for C. difficile infection
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September 10, 2025 at 8:39 PM
Weekend read! Our Special issue on Plants & Microbes

We present “growing insight” on cutting edge topics, from immune cell states to rewilding plant microbiomes to plant-microbe interactions amid global change.
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September 5, 2025 at 3:37 PM
Special Issue Alert for August!
Plants & Microbes: Growing Insight
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August 13, 2025 at 4:37 PM
Collection: Plants!!!

Browse our collection of recent reviews and articles on how microbes influence plant health, acting positively through beneficial interactions or negatively by causing disease.

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July 22, 2025 at 1:24 PM
Collection: Bugs as Drugs.
Enjoy our collection of recent reviews and articles exploring the impact of microbes on therapeutic efficacy as well as advancing capabilities to utilize microbes as therapeutics or in microbiome modulation
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July 17, 2025 at 6:47 PM
Featured Article: IFN-ε shields Neisseria

IFN-ε, a hormone-responsive type I IFN expressed by genital epithelial cells, boosts sialylation of Neisseria gonorrhoeae, which allows Neisseria to evade immune elimination

www.cell.com/cell-host-mi...
July 9, 2025 at 5:02 PM
Featured Article: Phage DNA modifications evade defense

Phage DNA modification adds arabinose to cytosines via hydroxy linkage(5ara-hC) w/potential double & triple arabinosylation. Arabinosylated phages are protected from CRISPR-Cas & restriction modification

www.cell.com/cell-host-mi...
July 9, 2025 at 5:00 PM
Our July issue is out today!

Cover art depicts precision antibacterial strategies that allow non-toxigenic V. cholerae to dominate toxigenic rivals.

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July 9, 2025 at 4:46 PM
Read our collection of papers on Cancer Microbiology!

Reviews and primary research on how microbes contribute to tumorigenesis and clinical outcomes.

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July 2, 2025 at 4:49 PM
Leveraging diurnal shifts in bacterial transgenes:

Time-restricted feeding causes diurnal functional shifts in microbes. D. newyorkensis bile salt hydrolase exhibits diurnal expression. DnBSH1-E. coli improves glucose metabolism & reduces body fat in mice

www.cell.com/cell-host-mi...
June 24, 2025 at 9:38 PM
IFN-ε shields Neisseria

New work examines IFN-ε, a hormone-responsive type I IFN expressed by genital epithelial cells, during N. gonorrhoeae infection. IFN-ε boosts sialylation of Ng, which allows Ng to evade immune elimination
www.cell.com/cell-host-mi...
June 23, 2025 at 6:32 PM
Rhizosphere microbes mitigate shade avoidance:

Shade avoidance helps plants reach maximal light while weakening immunity & yield. New work finds rhizosphere microbes mitigate shade avoidance w/FLS2-BAK1 & MYC2, PIFs & HY5 delivering rhizosphere signals
www.cell.com/cell-host-mi...
June 19, 2025 at 12:04 PM
Single-tooth prediction of childhood caries:
• Dental plaque microbiota patterns in children are predictive of tooth-specific caries development.
• Spatial-MiC model, integrating microbial and spatial data, improves caries forecasting with 93% accuracy

www.cell.com/cell-host-mi...
June 18, 2025 at 12:45 PM
Unlocking the power of human milk and infant feeding:
Understanding how nutrition and early microbiota interaction shapes health programming

Review by Zhernakova, Yassour, Hall & Collado

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June 18, 2025 at 12:41 PM
Bacterial sphingolipids promote anti-inflammatory responses:

Bacteroides sphingolipids delivered by OMVs persist w/in mammalian immune cells & promote IL-10 secretion via mevalonate pathway to drive anti-inflammatory responses

www.cell.com/cell-host-mi...
June 16, 2025 at 9:15 PM
Microbiome-facilitated plant nutrient acquisition:

Review by Singh et al. examining impact of soil & plant microbiomes on plant nutrient acquisition & proposing a modified eco-evolutionary framework that considers plant & microbial communication mechanisms
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June 16, 2025 at 1:44 PM
Gut microbial enzymes & MASH: Function, mechanism & therapeutic prospects

Review by Luo, Wang & Jiang discussing role of gut microbial enzymes in progression of metabolic dysfunction-associated steatohepatitis & potential therapeutics targeting microbiota
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June 13, 2025 at 1:57 PM
The microbiome: An actor or stage for the beneficial action of probiotics, prebiotics, synbiotics, and postbiotics?

Perspective by Sanders & Hill examining evidence that health benefits of “biotics” result from impacts on the microbiome.

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June 11, 2025 at 6:20 PM
Origins and functions of microbiome rhythms

Review by Haller, Thaiss and Co summarizing the features of the microbiota that undergo diurnal rhythms, their development, their impact on the biology of the host, and their relevance to human health and disease

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June 11, 2025 at 6:10 PM
Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering

Review by Erik Bakkeren, Vit Piskovsky, and Kevin R. Foster
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June 11, 2025 at 5:02 PM
June marks a Special Issue at Cell Host & Microbe!

Enjoy our collection of perspectives, reviews, and primary research articles that capture cutting-edge insights into microbe and nutrient dynamics.

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June 11, 2025 at 4:38 PM
Bacterial sphingolipids promote anti-inflammatory responses:

Bacteroides sphingolipids delivered by OMVs persist w/in mammalian immune cells & promote IL-10 secretion via mevalonate pathway to drive anti-inflammatory responses
www.cell.com/cell-host-mi...
June 9, 2025 at 10:40 PM
Single-tooth prediction of childhood caries:

• Dental plaque microbiota patterns in children are predictive of tooth-specific caries development.
• Spatial-MiC model, integrating microbial and spatial data, improves caries forecasting with 93% accuracy

www.cell.com/cell-host-mi...
June 9, 2025 at 9:03 PM