@cmn-vib.bsky.social
Another local one in our #CMNconsortia series:
We're part of µNEURO, a UAntwerp Research Centre of Excellence uniting neuropathology, genomics, and quantitative multimodal imaging to uncover pathogenic mechanisms in neurodevelopmental and neurodegenerative disorders.
https://tinyurl.com/24vhk8v6
We're part of µNEURO, a UAntwerp Research Centre of Excellence uniting neuropathology, genomics, and quantitative multimodal imaging to uncover pathogenic mechanisms in neurodevelopmental and neurodegenerative disorders.
https://tinyurl.com/24vhk8v6
November 13, 2025 at 1:17 PM
Another local one in our #CMNconsortia series:
We're part of µNEURO, a UAntwerp Research Centre of Excellence uniting neuropathology, genomics, and quantitative multimodal imaging to uncover pathogenic mechanisms in neurodevelopmental and neurodegenerative disorders.
https://tinyurl.com/24vhk8v6
We're part of µNEURO, a UAntwerp Research Centre of Excellence uniting neuropathology, genomics, and quantitative multimodal imaging to uncover pathogenic mechanisms in neurodevelopmental and neurodegenerative disorders.
https://tinyurl.com/24vhk8v6
Reposted
C9orf72 mutations impair immune activation in ALS, highlighting key differences in the cellular and molecular pathways underlying sporadic and genetics forms of the disease
@mancusorenzo.bsky.social @c9laura72.bsky.social @baukje-bij.bsky.social @cmn-vib.bsky.social
www.nature.com/articles/s41...
@mancusorenzo.bsky.social @c9laura72.bsky.social @baukje-bij.bsky.social @cmn-vib.bsky.social
www.nature.com/articles/s41...
C9orf72 hexanucleotide repeat expansions impair microglial response in ALS - Nature Neuroscience
This study shows that C9orf72 mutations impair immune activation in ALS, affecting how brain cells communicate, and highlights key differences in the cellular and molecular pathways underlying sporadi...
www.nature.com
October 23, 2025 at 7:25 PM
C9orf72 mutations impair immune activation in ALS, highlighting key differences in the cellular and molecular pathways underlying sporadic and genetics forms of the disease
@mancusorenzo.bsky.social @c9laura72.bsky.social @baukje-bij.bsky.social @cmn-vib.bsky.social
www.nature.com/articles/s41...
@mancusorenzo.bsky.social @c9laura72.bsky.social @baukje-bij.bsky.social @cmn-vib.bsky.social
www.nature.com/articles/s41...
Reposted
Last Friday, we shared our research with 1st year Master's students at @uantwerpen.be during the Research Day! We loved their genuine interest and look forward to welcoming several of them to our lab next year.
Great to see Ph.D. students Kato and Ella share their love for science! 🧪
Great to see Ph.D. students Kato and Ella share their love for science! 🧪
October 28, 2025 at 9:31 AM
Last Friday, we shared our research with 1st year Master's students at @uantwerpen.be during the Research Day! We loved their genuine interest and look forward to welcoming several of them to our lab next year.
Great to see Ph.D. students Kato and Ella share their love for science! 🧪
Great to see Ph.D. students Kato and Ella share their love for science! 🧪
New paper alert! 🚨
The Jordanova lab contributed to a major international study uncovering the genetic cause of a childhood-onset, motor-predominant neuropathy.
The team identified one of the 20 families as part of this multicenter collaboration.
📄 https://www.jci.org/articles/view/184474
The Jordanova lab contributed to a major international study uncovering the genetic cause of a childhood-onset, motor-predominant neuropathy.
The team identified one of the 20 families as part of this multicenter collaboration.
📄 https://www.jci.org/articles/view/184474
October 24, 2025 at 7:17 AM
New paper alert! 🚨
The Jordanova lab contributed to a major international study uncovering the genetic cause of a childhood-onset, motor-predominant neuropathy.
The team identified one of the 20 families as part of this multicenter collaboration.
📄 https://www.jci.org/articles/view/184474
The Jordanova lab contributed to a major international study uncovering the genetic cause of a childhood-onset, motor-predominant neuropathy.
The team identified one of the 20 families as part of this multicenter collaboration.
📄 https://www.jci.org/articles/view/184474
One of the newest consortia we are part of is TRANSGEN.
In this consortium, CMN PIs team up colleagues from the UZA-UAntwerp Center of Medical Genetics to advance the translation of genomic and epigenomic insights into novel biomarkers and innovative therapies.
#CMNcohorts #CMNconsortia
In this consortium, CMN PIs team up colleagues from the UZA-UAntwerp Center of Medical Genetics to advance the translation of genomic and epigenomic insights into novel biomarkers and innovative therapies.
#CMNcohorts #CMNconsortia
October 23, 2025 at 2:14 PM
One of the newest consortia we are part of is TRANSGEN.
In this consortium, CMN PIs team up colleagues from the UZA-UAntwerp Center of Medical Genetics to advance the translation of genomic and epigenomic insights into novel biomarkers and innovative therapies.
#CMNcohorts #CMNconsortia
In this consortium, CMN PIs team up colleagues from the UZA-UAntwerp Center of Medical Genetics to advance the translation of genomic and epigenomic insights into novel biomarkers and innovative therapies.
#CMNcohorts #CMNconsortia
Today, the 2nd European CMT Specialist Conference kicks off, right here in Antwerp! 🎉
The Jordanova lab is well represented with Ayşe Candayan is giving a talk and Akram Khanghahi and Alexandra Ekshteyn are presenting posters
www.uantwerpen.be/en/conferences/2nd-european-cmt-specialist-conference/
The Jordanova lab is well represented with Ayşe Candayan is giving a talk and Akram Khanghahi and Alexandra Ekshteyn are presenting posters
www.uantwerpen.be/en/conferences/2nd-european-cmt-specialist-conference/
October 23, 2025 at 11:34 AM
Today, the 2nd European CMT Specialist Conference kicks off, right here in Antwerp! 🎉
The Jordanova lab is well represented with Ayşe Candayan is giving a talk and Akram Khanghahi and Alexandra Ekshteyn are presenting posters
www.uantwerpen.be/en/conferences/2nd-european-cmt-specialist-conference/
The Jordanova lab is well represented with Ayşe Candayan is giving a talk and Akram Khanghahi and Alexandra Ekshteyn are presenting posters
www.uantwerpen.be/en/conferences/2nd-european-cmt-specialist-conference/
Sustainability is a team sport. 🙌
Credits to Sam Sluijs for coordinating the effort here at CMN.
Read more about our approach in this wonderful interview with Sam (pictures by Elisabeth Verwaest).
https://beakon.ghost.io/you-are-not-truly-working-safely-unless-you-are-also-working-sustainably/
Credits to Sam Sluijs for coordinating the effort here at CMN.
Read more about our approach in this wonderful interview with Sam (pictures by Elisabeth Verwaest).
https://beakon.ghost.io/you-are-not-truly-working-safely-unless-you-are-also-working-sustainably/
October 21, 2025 at 10:42 AM
Sustainability is a team sport. 🙌
Credits to Sam Sluijs for coordinating the effort here at CMN.
Read more about our approach in this wonderful interview with Sam (pictures by Elisabeth Verwaest).
https://beakon.ghost.io/you-are-not-truly-working-safely-unless-you-are-also-working-sustainably/
Credits to Sam Sluijs for coordinating the effort here at CMN.
Read more about our approach in this wonderful interview with Sam (pictures by Elisabeth Verwaest).
https://beakon.ghost.io/you-are-not-truly-working-safely-unless-you-are-also-working-sustainably/
Spotlight on Solve-RD: a consortium solving the unsolved in rare diseases 👇
Sarah Weckhuysen and Vincent Timmerman contribute to Solve-RD, a pan-European effort uniting ERNs, clinicians, patient groups, and -omics experts to crack undiagnosed rare diseases.
#CMNcohorts #CMNconsortia
Sarah Weckhuysen and Vincent Timmerman contribute to Solve-RD, a pan-European effort uniting ERNs, clinicians, patient groups, and -omics experts to crack undiagnosed rare diseases.
#CMNcohorts #CMNconsortia
October 16, 2025 at 12:32 PM
Spotlight on Solve-RD: a consortium solving the unsolved in rare diseases 👇
Sarah Weckhuysen and Vincent Timmerman contribute to Solve-RD, a pan-European effort uniting ERNs, clinicians, patient groups, and -omics experts to crack undiagnosed rare diseases.
#CMNcohorts #CMNconsortia
Sarah Weckhuysen and Vincent Timmerman contribute to Solve-RD, a pan-European effort uniting ERNs, clinicians, patient groups, and -omics experts to crack undiagnosed rare diseases.
#CMNcohorts #CMNconsortia
Reposted
Proud of this collaboration with Philip Van Damme’s team: we show that microglia and astrocytes behave differently in sporadic vs. C9orf72 ALS across human tissue, iPSC-derived cells and in vivo xenografts.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Client Challenge
www.nature.com
October 14, 2025 at 9:51 AM
Proud of this collaboration with Philip Van Damme’s team: we show that microglia and astrocytes behave differently in sporadic vs. C9orf72 ALS across human tissue, iPSC-derived cells and in vivo xenografts.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
New collaborative paper from the @mancusorenzo.bsky.social lab and Van Damme lab: the brain’s immune response differs in sporadic ALS vs. C9orf72 ALS. 🙌
Recap https://press.vib.be/same-symptoms-different-biology
Paper https://www.nature.com/articles/s41593-025-02075-1
@viblifesciences.bsky.social
Recap https://press.vib.be/same-symptoms-different-biology
Paper https://www.nature.com/articles/s41593-025-02075-1
@viblifesciences.bsky.social
C9orf72 hexanucleotide repeat expansions impair microglial response in ALS - Nature Neuroscience
This study shows that C9orf72 mutations impair immune activation in ALS, affecting how brain cells communicate, and highlights key differences in the cellular and molecular pathways underlying sporadic and genetic forms of the disease.
www.nature.com
October 14, 2025 at 9:59 AM
New collaborative paper from the @mancusorenzo.bsky.social lab and Van Damme lab: the brain’s immune response differs in sporadic ALS vs. C9orf72 ALS. 🙌
Recap https://press.vib.be/same-symptoms-different-biology
Paper https://www.nature.com/articles/s41593-025-02075-1
@viblifesciences.bsky.social
Recap https://press.vib.be/same-symptoms-different-biology
Paper https://www.nature.com/articles/s41593-025-02075-1
@viblifesciences.bsky.social
We kicked off day 2 of #NHND25 with a session on neuro-inflammation in neurodegeneration, featuring Xiaoying Chen, Katerina Akassoglou, and our very own @seppedeschepper.bsky.social.
October 10, 2025 at 9:38 AM
We kicked off day 2 of #NHND25 with a session on neuro-inflammation in neurodegeneration, featuring Xiaoying Chen, Katerina Akassoglou, and our very own @seppedeschepper.bsky.social.
Reposted
Interested in the role of T cells in Alzheimer’s? PhD student Amelia is presenting her exciting work at #NHND25 in Leuven. If you are there, check out her poster to learn more!
October 10, 2025 at 5:42 AM
Interested in the role of T cells in Alzheimer’s? PhD student Amelia is presenting her exciting work at #NHND25 in Leuven. If you are there, check out her poster to learn more!
Morning recap from #NHND25, where Albena Jordanova co-chaired the first session on better, human-relevant models for neurodegeneration, and Renzo Mancuso presented new data on how progranulin dosage shapes microglial trajectories.
Off to a great start!
@vibtrainconf.bsky.social
Off to a great start!
@vibtrainconf.bsky.social
October 9, 2025 at 12:51 PM
Morning recap from #NHND25, where Albena Jordanova co-chaired the first session on better, human-relevant models for neurodegeneration, and Renzo Mancuso presented new data on how progranulin dosage shapes microglial trajectories.
Off to a great start!
@vibtrainconf.bsky.social
Off to a great start!
@vibtrainconf.bsky.social
The European Alzheimer & Dementia Biobank (EADB) unites cohorts across 18 countries to decode the genetics of Alzheimer’s disease. https://eadb.eu/
At CMN, the @sleegerslab.bsky.social plays a leading role, with postdoc Fahri Küçükali as our in-house EADB specialist.
#CMNcohorts #CMNconsortia
At CMN, the @sleegerslab.bsky.social plays a leading role, with postdoc Fahri Küçükali as our in-house EADB specialist.
#CMNcohorts #CMNconsortia
October 9, 2025 at 11:47 AM
The European Alzheimer & Dementia Biobank (EADB) unites cohorts across 18 countries to decode the genetics of Alzheimer’s disease. https://eadb.eu/
At CMN, the @sleegerslab.bsky.social plays a leading role, with postdoc Fahri Küçükali as our in-house EADB specialist.
#CMNcohorts #CMNconsortia
At CMN, the @sleegerslab.bsky.social plays a leading role, with postdoc Fahri Küçükali as our in-house EADB specialist.
#CMNcohorts #CMNconsortia
Happy anniversary to the 1,000 Healthy Elderly Study! 🎂
On this day last year, we included our very first participant (again). Today we’re at 196 re-inclusions, and on track to hit 200 by the end of the week. 💪
A special thank you today to our study nurse, Sofie Van de kerckhoven! 🥳
#CMNcohorts
On this day last year, we included our very first participant (again). Today we’re at 196 re-inclusions, and on track to hit 200 by the end of the week. 💪
A special thank you today to our study nurse, Sofie Van de kerckhoven! 🥳
#CMNcohorts
October 7, 2025 at 11:22 AM
Happy anniversary to the 1,000 Healthy Elderly Study! 🎂
On this day last year, we included our very first participant (again). Today we’re at 196 re-inclusions, and on track to hit 200 by the end of the week. 💪
A special thank you today to our study nurse, Sofie Van de kerckhoven! 🥳
#CMNcohorts
On this day last year, we included our very first participant (again). Today we’re at 196 re-inclusions, and on track to hit 200 by the end of the week. 💪
A special thank you today to our study nurse, Sofie Van de kerckhoven! 🥳
#CMNcohorts
Did you know that caring for someone with FTD can be one of the most demanding caregiving roles?
During this World FTD Awareness Week, we acknowledge the burden carers carry. For us, patients and their families are true partners in research.
#endFTD #WorldFTDAwarenessWeek
During this World FTD Awareness Week, we acknowledge the burden carers carry. For us, patients and their families are true partners in research.
#endFTD #WorldFTDAwarenessWeek
September 26, 2025 at 12:52 PM
Did you know that caring for someone with FTD can be one of the most demanding caregiving roles?
During this World FTD Awareness Week, we acknowledge the burden carers carry. For us, patients and their families are true partners in research.
#endFTD #WorldFTDAwarenessWeek
During this World FTD Awareness Week, we acknowledge the burden carers carry. For us, patients and their families are true partners in research.
#endFTD #WorldFTDAwarenessWeek
We’re hiring! 📣
🎓🎓 2 PhD positions
🧬🧫 2 Postdocs
🥼 1 Lab Technician
🖥️ 1 IT profile
https://cmn.sites.vib.be/en/join-us
Please share!
🎓🎓 2 PhD positions
🧬🧫 2 Postdocs
🥼 1 Lab Technician
🖥️ 1 IT profile
https://cmn.sites.vib.be/en/join-us
Please share!
September 26, 2025 at 12:32 PM
We’re hiring! 📣
🎓🎓 2 PhD positions
🧬🧫 2 Postdocs
🥼 1 Lab Technician
🖥️ 1 IT profile
https://cmn.sites.vib.be/en/join-us
Please share!
🎓🎓 2 PhD positions
🧬🧫 2 Postdocs
🥼 1 Lab Technician
🖥️ 1 IT profile
https://cmn.sites.vib.be/en/join-us
Please share!
Next up in our #CMNcohorts #CMNconsortia series, we spotlight a collaboration between the @sleegerslab.bsky.social and Dietmar Thal at KU Leuven: a post-mortem brain cohort, now paired with genetic characterization, and transcriptomic profiling underway.
September 25, 2025 at 3:31 PM
Next up in our #CMNcohorts #CMNconsortia series, we spotlight a collaboration between the @sleegerslab.bsky.social and Dietmar Thal at KU Leuven: a post-mortem brain cohort, now paired with genetic characterization, and transcriptomic profiling underway.
“What if it’s FTD?”
World FTD Awareness Week kicked off right after World Alzheimer’s Day on Sunday, a timely reminder that while FTD is the second most common dementia, it’s not Alzheimer’s.
#endFTD
World FTD Awareness Week kicked off right after World Alzheimer’s Day on Sunday, a timely reminder that while FTD is the second most common dementia, it’s not Alzheimer’s.
#endFTD
September 24, 2025 at 3:47 PM
“What if it’s FTD?”
World FTD Awareness Week kicked off right after World Alzheimer’s Day on Sunday, a timely reminder that while FTD is the second most common dementia, it’s not Alzheimer’s.
#endFTD
World FTD Awareness Week kicked off right after World Alzheimer’s Day on Sunday, a timely reminder that while FTD is the second most common dementia, it’s not Alzheimer’s.
#endFTD
On #WorldAlzheimersDay, we’re reminded that progress is possible, and it’s powered by people. Every dataset, every partnership, every volunteer brings us closer to earlier detection and better treatments.
Thank you to our participants and collaborators. Hope moves forward together. 💜
Thank you to our participants and collaborators. Hope moves forward together. 💜
September 21, 2025 at 10:18 AM
On #WorldAlzheimersDay, we’re reminded that progress is possible, and it’s powered by people. Every dataset, every partnership, every volunteer brings us closer to earlier detection and better treatments.
Thank you to our participants and collaborators. Hope moves forward together. 💜
Thank you to our participants and collaborators. Hope moves forward together. 💜
When the gene is mapped, the work is far from done.
In this interview with Julie van der Zee, we talk why long-horizon science only delivers if relationships, records, and ethics are cared for as diligently as the data.
https://blog.vib.be/from-first-families-to-first-trials
In this interview with Julie van der Zee, we talk why long-horizon science only delivers if relationships, records, and ethics are cared for as diligently as the data.
https://blog.vib.be/from-first-families-to-first-trials
September 17, 2025 at 9:43 AM
When the gene is mapped, the work is far from done.
In this interview with Julie van der Zee, we talk why long-horizon science only delivers if relationships, records, and ethics are cared for as diligently as the data.
https://blog.vib.be/from-first-families-to-first-trials
In this interview with Julie van der Zee, we talk why long-horizon science only delivers if relationships, records, and ethics are cared for as diligently as the data.
https://blog.vib.be/from-first-families-to-first-trials
The Rademakers lab presents the most comprehensive analysis of DNA methylation patterns in FTLD-TDP to date, revealing that the molecular differences between disease subtypes run even deeper than previously recognized.
https://tinyurl.com/4cahyuup
https://tinyurl.com/4cahyuup
September 16, 2025 at 8:32 AM
The Rademakers lab presents the most comprehensive analysis of DNA methylation patterns in FTLD-TDP to date, revealing that the molecular differences between disease subtypes run even deeper than previously recognized.
https://tinyurl.com/4cahyuup
https://tinyurl.com/4cahyuup
That’s a wrap on the 2025 BioHackathon!
From 8 to 10 Sept, three hubs, at the University of Cambridge, VIB-University of Antwerp Center for Neurology, and Newcastle University, coded in sync on bioinformatics, math & computational biology.
See you at the next edition!
From 8 to 10 Sept, three hubs, at the University of Cambridge, VIB-University of Antwerp Center for Neurology, and Newcastle University, coded in sync on bioinformatics, math & computational biology.
See you at the next edition!
September 12, 2025 at 6:12 AM
That’s a wrap on the 2025 BioHackathon!
From 8 to 10 Sept, three hubs, at the University of Cambridge, VIB-University of Antwerp Center for Neurology, and Newcastle University, coded in sync on bioinformatics, math & computational biology.
See you at the next edition!
From 8 to 10 Sept, three hubs, at the University of Cambridge, VIB-University of Antwerp Center for Neurology, and Newcastle University, coded in sync on bioinformatics, math & computational biology.
See you at the next edition!
We’re hiring a part-time (Junior) Linux System Administrator 📣
Join a small, collaborative IT team and support cutting-edge neuroscience research.
https://cmn.sites.vib.be/en/join-us#/job-description/122451
Join a small, collaborative IT team and support cutting-edge neuroscience research.
https://cmn.sites.vib.be/en/join-us#/job-description/122451
September 9, 2025 at 3:07 PM
We’re hiring a part-time (Junior) Linux System Administrator 📣
Join a small, collaborative IT team and support cutting-edge neuroscience research.
https://cmn.sites.vib.be/en/join-us#/job-description/122451
Join a small, collaborative IT team and support cutting-edge neuroscience research.
https://cmn.sites.vib.be/en/join-us#/job-description/122451
Huge congratulations to Sebastiaan De Schepper on obtaining a prestigious ERC grant to launch PRIME-PD, a project uncovering how the immune system helps initiate and drive Parkinson’s disease. 🙌
September 4, 2025 at 12:14 PM
Huge congratulations to Sebastiaan De Schepper on obtaining a prestigious ERC grant to launch PRIME-PD, a project uncovering how the immune system helps initiate and drive Parkinson’s disease. 🙌