Claire Shanahan
claireshan.bsky.social
Claire Shanahan
@claireshan.bsky.social
My passions are understanding as much about dementia as I possibly can, promotion of good mental health, music, Manchester city and travel. Love the arts in general. All of my views are my own and not necessarily that of others.
Reposted by Claire Shanahan
@CBSNews: The FDA approved a new Alzheimer's treatment called donanemab on Tuesday, clearing the way for the third addition to a new class of drugs aimed at slowing the brain's decline in patients facing the early stages of the disease. https://t.co/CHrGkQJhho https://t.co/w98vaZtf0z
July 2, 2024 at 9:49 PM
Reposted by Claire Shanahan
Some possibly good news:
FDA advisors recommend Eli Lilly's Alzheimer's drug donanemab, paving way for approval
www.cnbc.com/2024/06/10/f...
FDA advisors recommend Eli Lilly's Alzheimer's drug donanemab, paving way for approval
If approved, Eli Lilly's donanemab would become the second Alzheimer's drug of its kind currently on the U.S. market after Leqembi from Biogen and Eisai.
www.cnbc.com
June 10, 2024 at 9:15 PM
Reposted by Claire Shanahan
Data from the TRAILBLAZER-ALZ 2 long-term extension study demonstrated that donanemab continues to deliver meaningful benefits in reducing Alzheimer's progression especially when started early. www.medscape.com/viewarticle/... #Medsky
Alzheimer’s Med Continues to Deliver Benefit at 3 Years
Longer-term data show that donanemab’s cognitive benefits continue to grow over time, and earlier initiation reduces the risk for progression, with no new safety signals.
www.medscape.com
August 23, 2025 at 1:35 AM
Reposted by Claire Shanahan
🧠 Alzheimer's Treatment Update: New drugs may cause brain swelling/bleeding

Anti-amyloid-β (Aβ) monoclonal antibodies like lecanemab and donanemab are shifting Alzheimer's treatment from symptom management to disease modification. They show modest slowing of cognitive decline in early AD.

1/2
September 21, 2025 at 3:01 PM
Reposted by Claire Shanahan
🧠 New analysis in @thelancet.com has shown, for the first time, that Alzheimer’s drugs lecanemab and donanemab can slow disease progression.

The anti-amyloid antibody medications allow patients to preserve functional independence.

@uclh.bsky.social @ucl.ac.uk @uclbrainscience.bsky.social
New medications for Alzheimer’s disease comparable in effectiveness to approved drugs in cancer, MS and arthritis
New medications for Alzheimer’s disease – which are not yet approved in some countries – have shown for the first time that clinical decline can be slowed with comparable effectiveness to approved med...
www.uclhospitals.brc.nihr.ac.uk
September 24, 2025 at 2:21 PM
Reposted by Claire Shanahan
New study: elevated brain iron may predict cognitive decline years before Alzheimer’s symptoms appear, especially in the presence of amyloid burden.

Follow MCI and Beyond for updates

#BrainHealth #CognitiveDecline #Neuroscience #AlzheimerResearch #EarlyDetection
September 25, 2025 at 1:51 PM
Reposted by Claire Shanahan
Dementia raises delirium risk, and delirium can worsen or speed up dementia symptoms. Why aren’t we studying this more? Read Dr Ameen-Ali’s blog. @kamarameenali.bsky.social

www.dementiaresearcher.nihr.ac.uk/blog-deliriu...
Blog – Delirium and dementia: A neglected area of research? - DEMENTIA RESEARCHER
Dr Kamar Ameen-Ali explores the overlooked link between delirium and dementia, highlighting risks, misdiagnosis, and the urgent need for more research.
www.dementiaresearcher.nihr.ac.uk
September 3, 2025 at 7:22 AM
Reposted by Claire Shanahan
Dr Peter Connelly shares how clinical research can be integrated into everyday care and why it matters for patients and clinicians alike. Read or listen to the full blog.

www.dementiaresearcher.nihr.ac.uk/blog-balanci...
Dr Peter Connelly - Blog – Balancing Clinical Research with a Clinical Career
Dr Peter Connelly on balancing clinical research with a clinical career, showing how small steps can make research part of everyday practice.
www.dementiaresearcher.nihr.ac.uk
September 9, 2025 at 9:50 PM
Reposted by Claire Shanahan
Explore our new special collection Becoming a Researcher – podcasts, blogs, webinars & stories of unique journeys into dementia research, from nursing & psychology to arts & neuroscience.

www.dementiaresearcher.nihr.ac.uk/collections/...
Special Collection - Becoming a Researcher - DEMENTIA RESEARCHER
Special Collection: Explore blogs, podcasts and webinars where researchers share their lives, journeys, and diverse paths into research careers
www.dementiaresearcher.nihr.ac.uk
August 19, 2025 at 3:50 PM
Reposted by Claire Shanahan
When Cancer Thinks Like Dementia: A Surprising Cellular Connection

What if the earliest signs of pancreatic cancer looked eerily similar to what happens in the brain during dementia? That’s the provocative question raised by new research from the Cancer Research UK Scotland Centre, where…
When Cancer Thinks Like Dementia: A Surprising Cellular Connection
What if the earliest signs of pancreatic cancer looked eerily similar to what happens in the brain during dementia? That’s the provocative question raised by new research from the Cancer Research UK Scotland Centre, where scientists have uncovered a startling biological overlap between two seemingly unrelated diseases. In a study published in Developmental Cell, researchers tracked pancreatic cells in mice to understand how normal cells begin their transformation into cancer.
rippie77.wordpress.com
August 31, 2025 at 9:57 AM
Reposted by Claire Shanahan
9/15 at 7:30 PM | Allyson Schrier shares her journey from supporting a spouse with dementia to cofounding Zinnia TV—a streaming service delivering research-backed video content for people living with dementia.

🎟 Get tickets: buff.ly/3NCiTOS
August 15, 2025 at 7:01 PM
Reposted by Claire Shanahan
We can alleviate some of the isolation, loneliness, and pain of #dementia.

#Alzheimers #kindness #poetry
August 15, 2025 at 5:14 PM
Reposted by Claire Shanahan
“Everyday acts of support — whether organized or personal — can have lasting cognitive impact.”
— Sae Hwang Han, study lead & UT Austin asst. prof. of human development & family sciences

#HelpingOthers #CognitiveDecline #CognitiveAging #TexasScience @umassboston.bsky.social @utaustin.bsky.social
Helping Others Shown To Slow Cognitive Decline
Regular volunteering or helping others outside the home can reduce the rate of cognitive aging by 15-20%.
cns.utexas.edu
August 15, 2025 at 6:57 PM
Reposted by Claire Shanahan
Two months after moving her husband to memory care, Chick writes about what’s changed and what hasn’t.
There’s still grief. But also laughter, goodbyes, and a favorite story about a stubborn lock and a smarter response.
#alzheimers #caregiving #clearviewworks
www.clearviewworks.org/post/hot-wom...
Hot Woman! Or Well done.
I’ve been living in the pain and trauma of having to move my husband to memory care.  It has been a difficult time these past two months.  We’ve both struggled through the adjustment to our lives.  He...
www.clearviewworks.org
July 27, 2025 at 1:25 AM
Reposted by Claire Shanahan
July 26, 1986

Peter Gabriel hits #1 in the US with "Sledgehammer," bumping his old band, Genesis (with "Invisible Touch") out of the top spot. 🎶🎤🤘

#ClassicRock
#RockNRoll
#ClassicVinyl
#MusicSky

youtu.be/OJWJE0x7T4Q?...
Peter Gabriel - Sledgehammer (HD version)
YouTube video by Peter Gabriel
youtu.be
July 26, 2025 at 12:35 PM
Reposted by Claire Shanahan
BBC Radio 6 Music
Cerys Matthews

Now Playing
The Quantic Soul Orchestra
Pushin' On (feat. Alice Russell)
July 27, 2025 at 9:05 AM
Reposted by Claire Shanahan
Support the 2025/26 In2research programme. Mentor or host a placement to help widen access to research careers for people from underrepresented backgrounds.

www.dementiaresearcher.nihr.ac.uk/in2research-...
July 24, 2025 at 9:00 AM
Reposted by Claire Shanahan
The earlier #Alzheimers disease is detected, the more effective treatments become. Now, a population study conducted at 🇫🇮 @utu.fi shows that signs related to Alzheimer’s may already be found in the #brain in middle age.
Alzheimer's: middle-age brain biomarkers give an earlier shot at prevention
A Finnish population study shows that signs related to Alzheimer’s disease may already be found in the brain in middle age. In the future, blood-based biomarkers associated with Alzheimer's disease co...
healthcare-in-europe.com
July 24, 2025 at 6:35 AM
Reposted by Claire Shanahan
Two new studies of former professional rugby players found no cases of early-onset dementia, but did find potential signs of increased risk of developing dementia in later life, report a team involving researchers at @uclmedsci.bsky.social, @uclqsion.bsky.social & @theiseh.bsky.social
Dementia is rare in midlife rugby players, but long-term risk may be increased
Two new studies of former rugby players, involving UCL researchers, found no cases of early-onset dementia but did find potential signs of increased risk of developing dementia later on.
www.ucl.ac.uk
July 3, 2025 at 5:01 PM
Yes why does great dementia research stop short of real world use?
July 3, 2025 at 9:45 PM
Reposted by Claire Shanahan
"We urgently need prevention strategies that move beyond individual willpower." Dr Jodi Watt challenges how we frame dementia prevention.

www.dementiaresearcher.nihr.ac.uk/blog-who-get...
Dr Jodi Watt - Blog – Who Gets Left Out of Dementia Prevention?
Who gets left out of dementia prevention efforts? Dr Jodi Watt highlights how social inequity shapes risk and why we must rethink prevention for everyone.
www.dementiaresearcher.nihr.ac.uk
July 2, 2025 at 9:38 PM
Reposted by Claire Shanahan
A study published in Alzheimer’s Research & Therapy finds that women consistently exhibit earlier hippocampal atrophy and a higher burden of white matter abnormalities compared to men, yet women display less cognitive decline over time.
bit.ly/42kuzXN

#MedSky #alzsky
July 3, 2025 at 5:30 PM
Football reminiscence 😊
July 3, 2025 at 9:41 PM