🚨 New Preprint 🚨

Targeting intracranial electrical stimulation (ES) to network regions defined within individuals causes network-level effects

By Cyr et al.

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Q: Can we use individualized network maps from precision fMRI to modulate a targeted network via intracranial ES?

A: Yes!

🧵:

Precision Functional Mapping (PFM). 8 yrs ago some told us it wasn't interesting. Now it's helping cure depression as part of PACE (Personalized Adaptive Cortical Electro-stimulation), ... commercialized by @turingmedical.bsky.social.

osf.io/preprints/ps...
www.cell.com/neuron/comme...

I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...