Chris Crnich
cjcrnich.bsky.social
Chris Crnich
@cjcrnich.bsky.social
ID doc, antibiotic steward, and healthcare epidemiologist with a long-term care bent.
#idbluesky anyone with a suggestion on how to treat a severe thoracic space infection with this pathogen? Currently have pt on levo, ceftol/tazo & tobra
November 26, 2024 at 5:31 PM
Reposted by Chris Crnich
This is really interesting! #AMR #UTISky
📣 New perspective paper: Insights into durability against resistance from the antibiotic nitrofurantoin

We discuss what makes nitrofurantoin robust against resistance evolution, in spite of prolonged and extensive usage against UTIs #MicroSky

Open access/CC-BY-4.0: www.nature.com/articles/s44...
Insights into durability against resistance from the antibiotic nitrofurantoin - npj Antimicrobials and Resistance
npj Antimicrobials and Resistance - Insights into durability against resistance from the antibiotic nitrofurantoin
www.nature.com
November 25, 2024 at 8:50 AM
Reposted by Chris Crnich
Fantastic piece by #WashU #ID faculty Jason Burnham on outpatient stewardship and financial incentives.

academic.oup.com/cid/advance-...
Behavioral Boosts, Getting More Bang for Your Buck: Financial incentives for outpatient antibiotic stewardship
Jason Burnham, MD, MSCI, Robin L P Jump, MD, PhD; Behavioral Boosts, Getting More Bang for Your Buck: Financial incentives for outpatient antibiotic stewar
academic.oup.com
November 24, 2024 at 2:20 AM
Reposted by Chris Crnich
Meant to share this study by @merellambregts.bsky.social's team
@cjcrnich.bsky.social 😊 when you & I were on #Breakpoints we were asked whether there was a pyuria cutoff to help differentiate btw infection & colonization
Here may be one (in elderly ♀️ at least) #IDSky
academic.oup.com/cid/article/...
Current Pyuria Cutoffs Promote Inappropriate Urinary Tract Infection Diagnosis in Older Women
The degree of pyuria can help distinguish urinary tract infection (UTI) in older women from asymptomatic women with and without bacteriuria. We demonstrate
academic.oup.com
November 23, 2024 at 5:27 PM
Reposted by Chris Crnich
retrospective study unit-spec combo-abxgram guided vs patient-spec risk factor. both provided hi appropriateness in emp abx selection. Patient-specrisk factor–based approach demonstrated a higher rate of appropriate therapy and offered advantages in reducing unnecessary combination therapy #idsky
A Comparison of Different Strategies for Optimizing the Selection of Empiric Antibiotic Therapy for Pneumonia Caused by Gram-Negative Bacteria in Intensive Care Units: Unit-Specific Combination Antibi...
Both unit-specific combination antibiograms and patient-specific factors help improve the appropriateness of empiric antibiotic selection for intensive car
academic.oup.com
November 23, 2024 at 2:53 PM
Reposted by Chris Crnich
Day 18 #30DayMapChallenge
I 3D-printed John Snow's 1854 cholera map of Soho. It took ages.
November 18, 2024 at 2:28 PM
Reposted by Chris Crnich

🆕️⚡️ ⚡️ #ofid
Implementing oral antibiotics for bone and joint infections: Lessons learned and opportunities for improvement #idsky academic.oup.com/ofid/article...
academic.oup.com/ofid/advance...
Implementing oral antibiotics for bone and joint infections: Lessons learned and opportunities for improvement
AbstractBackground. Although intravenous antibiotics have historically been the standard of care for bone and joint infections, clinical trial data has hig
academic.oup.com
November 16, 2024 at 7:40 PM