Chris Waudby
@chriswaudby.bsky.social
Lecturer in Biomolecular NMR at UCL School of Pharmacy. Pianist, opera lover, swimmer and cyclist with an inadvertent interest in religion and science. He/him 🏳️🌈
waudbylab.org
https://orcid.org/0000-0001-7810-3753
waudbylab.org
https://orcid.org/0000-0001-7810-3753
Reposted by Chris Waudby
Dr Chris Morris and I have a new paper in Nucleic Acids Research.
This paper has been a long time in the making & was affected by COVID so we are proud to have it published!
@shozebhaider.bsky.social
@effrosynialexandr.bsky.social
@chriswaudby.bsky.social
academic.oup.com/nar/article/...
This paper has been a long time in the making & was affected by COVID so we are proud to have it published!
@shozebhaider.bsky.social
@effrosynialexandr.bsky.social
@chriswaudby.bsky.social
academic.oup.com/nar/article/...
Affinity-selected peptide ligands specifically bind i-motif DNA and modulate c-Myc gene expression
Abstract. c-Myc is an oncogene that is dysregulated in ∼70% of cancers. Its multifaceted function complicates effective drug targeting of the protein. i-Mo
academic.oup.com
November 7, 2025 at 4:34 PM
Dr Chris Morris and I have a new paper in Nucleic Acids Research.
This paper has been a long time in the making & was affected by COVID so we are proud to have it published!
@shozebhaider.bsky.social
@effrosynialexandr.bsky.social
@chriswaudby.bsky.social
academic.oup.com/nar/article/...
This paper has been a long time in the making & was affected by COVID so we are proud to have it published!
@shozebhaider.bsky.social
@effrosynialexandr.bsky.social
@chriswaudby.bsky.social
academic.oup.com/nar/article/...
So excited that our lab's first home-grown paper is now available on ChemRxiv!
Kinetic NMR screening: rapidly quantifying fast ligand dissociation in fragment mixtures using ¹⁹F relaxation dispersion | doi.org/10.26434/che... 🧲🧪
Kinetic NMR screening: rapidly quantifying fast ligand dissociation in fragment mixtures using ¹⁹F relaxation dispersion | doi.org/10.26434/che... 🧲🧪
Kinetic NMR screening: rapidly quantifying fast ligand dissociation in fragment mixtures using ¹⁹F relaxation dispersion
Ligand-observed NMR is a key tool for detecting weak protein-ligand interactions, but translating binding signals into meaningful affinity measurements remains difficult, limiting the ability to rank ...
doi.org
September 24, 2025 at 12:54 PM
So excited that our lab's first home-grown paper is now available on ChemRxiv!
Kinetic NMR screening: rapidly quantifying fast ligand dissociation in fragment mixtures using ¹⁹F relaxation dispersion | doi.org/10.26434/che... 🧲🧪
Kinetic NMR screening: rapidly quantifying fast ligand dissociation in fragment mixtures using ¹⁹F relaxation dispersion | doi.org/10.26434/che... 🧲🧪
Celebrating the submission of my lab’s first fully home-grown paper 🥂 Appearing on @chemrxiv.org soon!
September 19, 2025 at 7:46 PM
Celebrating the submission of my lab’s first fully home-grown paper 🥂 Appearing on @chemrxiv.org soon!
Looking forward to giving a webinar tomorrow with @nickynak3.bsky.social about our efforts to establish a 19F NMR fragment screening platform at UCL. Register below and join us to find out more!
Friday 19th September, 2pm (UK)
www.eventbrite.co.uk/e/webinar-fr... #NMRchat #NMR @ucltro.bsky.social
Friday 19th September, 2pm (UK)
www.eventbrite.co.uk/e/webinar-fr... #NMRchat #NMR @ucltro.bsky.social
Webinar: Fragment Screening using 19F NMR at the UCL School of Pharmacy
Join Dr Nikita Harvey and Dr Christopher Waudby to delve into the subject and interact with research fellows.
www.eventbrite.co.uk
September 18, 2025 at 3:48 PM
Looking forward to giving a webinar tomorrow with @nickynak3.bsky.social about our efforts to establish a 19F NMR fragment screening platform at UCL. Register below and join us to find out more!
Friday 19th September, 2pm (UK)
www.eventbrite.co.uk/e/webinar-fr... #NMRchat #NMR @ucltro.bsky.social
Friday 19th September, 2pm (UK)
www.eventbrite.co.uk/e/webinar-fr... #NMRchat #NMR @ucltro.bsky.social
Many congratulations Mirek and Tomáš - it was a pleasure to be a part of the day and I’ve come away knowing a lot more about Wnt!
Big day for Bryjalab yesterday! Mirek Micka & Tomáš Gybeľ nailed their defences — welcome to the PhD club! 🎓🔥 Thanks to everyone who supported them along the way and came to celebrate! 🎉🤗
September 13, 2025 at 2:10 PM
Many congratulations Mirek and Tomáš - it was a pleasure to be a part of the day and I’ve come away knowing a lot more about Wnt!
Reposted by Chris Waudby
The science marathon continues. 🏃
Straight off #EBBM2025, BryjaLab is co-organizing with Tripsianes’ lab at @ceitec.eu the Milestone Minisymposium on Cell Signalling, kicking off today with great talks by @chriswaudby.bsky.social & @michaelranes.bsky.social. More talks & two PhD defenses tomorrow 🎓
Straight off #EBBM2025, BryjaLab is co-organizing with Tripsianes’ lab at @ceitec.eu the Milestone Minisymposium on Cell Signalling, kicking off today with great talks by @chriswaudby.bsky.social & @michaelranes.bsky.social. More talks & two PhD defenses tomorrow 🎓
September 11, 2025 at 7:04 PM
The science marathon continues. 🏃
Straight off #EBBM2025, BryjaLab is co-organizing with Tripsianes’ lab at @ceitec.eu the Milestone Minisymposium on Cell Signalling, kicking off today with great talks by @chriswaudby.bsky.social & @michaelranes.bsky.social. More talks & two PhD defenses tomorrow 🎓
Straight off #EBBM2025, BryjaLab is co-organizing with Tripsianes’ lab at @ceitec.eu the Milestone Minisymposium on Cell Signalling, kicking off today with great talks by @chriswaudby.bsky.social & @michaelranes.bsky.social. More talks & two PhD defenses tomorrow 🎓
I’m carrying out a short survey of NMR TITAN users - if you’ve made use of this tool in your research, or have suggestions for its future development, I’d be grateful for your input: forms.gle/MMXYwSozszhi... #nmrchat
NMR TITAN user survey
This survey aims to assess the impact of NMR TITAN on biomolecular research and identify priorities for future development. The form should take approximately 5 minutes to complete. Your responses may...
forms.gle
August 28, 2025 at 2:13 PM
I’m carrying out a short survey of NMR TITAN users - if you’ve made use of this tool in your research, or have suggestions for its future development, I’d be grateful for your input: forms.gle/MMXYwSozszhi... #nmrchat
Thrilled to be at the opening of the UK’s first 1.2 GHz NMR spectrometer at Warwick University, soon to be followed by a second in Birmingham! A huge investment in the NMR community from @ukri.org - I can’t wait to collect my first spectra and see what new discoveries will emerge! #nmrchat
August 14, 2025 at 1:58 PM
Reposted by Chris Waudby
Fragment Screening using 19F NMR at the UCL School of Pharmacy: Principles, Practice, and Applications
Date: Friday 19 Sep, 2-3pm
Speaker: Dr Nikita Harvey, Specialist Services Manager (NMR); Dr Christopher Waudby, Lecturer in Biomolecular NMR at the School of Pharmacy
✅Register now: bit.ly/4lpBftT
Date: Friday 19 Sep, 2-3pm
Speaker: Dr Nikita Harvey, Specialist Services Manager (NMR); Dr Christopher Waudby, Lecturer in Biomolecular NMR at the School of Pharmacy
✅Register now: bit.ly/4lpBftT
Webinar: Fragment Screening using 19F NMR at the UCL School of Pharmacy
Join Dr Nikita Harvey and Dr Christopher Waudby to delve into the subject and interact with research fellows.
bit.ly
August 14, 2025 at 9:01 AM
Fragment Screening using 19F NMR at the UCL School of Pharmacy: Principles, Practice, and Applications
Date: Friday 19 Sep, 2-3pm
Speaker: Dr Nikita Harvey, Specialist Services Manager (NMR); Dr Christopher Waudby, Lecturer in Biomolecular NMR at the School of Pharmacy
✅Register now: bit.ly/4lpBftT
Date: Friday 19 Sep, 2-3pm
Speaker: Dr Nikita Harvey, Specialist Services Manager (NMR); Dr Christopher Waudby, Lecturer in Biomolecular NMR at the School of Pharmacy
✅Register now: bit.ly/4lpBftT
Reposted by Chris Waudby
Today we're having a cooling/heating rack installed into our NMR liquid handling robot! This should help keep protein and DNA samples stable during prep for our 19F fragment screening service #NMRchat
www.ucl.ac.uk/pharmacy/abo...
www.ucl.ac.uk/pharmacy/abo...
July 10, 2025 at 10:34 AM
Today we're having a cooling/heating rack installed into our NMR liquid handling robot! This should help keep protein and DNA samples stable during prep for our 19F fragment screening service #NMRchat
www.ucl.ac.uk/pharmacy/abo...
www.ucl.ac.uk/pharmacy/abo...
Reposted by Chris Waudby
This is a great opportunity to join our group as PhD student to investigate the role(s) of intrinsically disordered proteins in biomedicine !
🚀 Ready to take your passion for science to the next level? Pursue a #PhD in a world-class research environment with us!
✨Kickstart your dream career. Your journey in #biomedicine begins here!
Check out our fellowships programs below!
🧪
✨Kickstart your dream career. Your journey in #biomedicine begins here!
Check out our fellowships programs below!
🧪
November 26, 2024 at 12:49 PM
This is a great opportunity to join our group as PhD student to investigate the role(s) of intrinsically disordered proteins in biomedicine !
I'll be performing in the UCL Chamber Music Club's next concert, 5.30 pm on Wed 4th Dec. Come and join us for a programme of piano music for 2 and 4 hands spanning three continents. Admission is free and open to all.
www.ucl.ac.uk/chamber-musi...
www.ucl.ac.uk/chamber-musi...
November 25, 2024 at 9:38 PM
I'll be performing in the UCL Chamber Music Club's next concert, 5.30 pm on Wed 4th Dec. Come and join us for a programme of piano music for 2 and 4 hands spanning three continents. Admission is free and open to all.
www.ucl.ac.uk/chamber-musi...
www.ucl.ac.uk/chamber-musi...
Pushed a new update to NMRTools.jl this afternoon, with some bug fixes and improved compatibility with Windows files.
Find out more at: waudbylab.org/NMRTools.jl/...
🧲 #julia
Find out more at: waudbylab.org/NMRTools.jl/...
🧲 #julia
Home · NMRTools.jl
Documentation for NMRTools.jl.
waudbylab.org
November 25, 2024 at 9:26 PM
Pushed a new update to NMRTools.jl this afternoon, with some bug fixes and improved compatibility with Windows files.
Find out more at: waudbylab.org/NMRTools.jl/...
🧲 #julia
Find out more at: waudbylab.org/NMRTools.jl/...
🧲 #julia
Reposted by Chris Waudby
Bluesky is really taking off with STEM academics across UCL, so I thought it was time we had our own Starter Pack
#academicsky #chemsky #stem #sciencesky #research #chemeng
go.bsky.app/9ZnMnCd
#academicsky #chemsky #stem #sciencesky #research #chemeng
go.bsky.app/9ZnMnCd
November 25, 2024 at 1:05 PM
Bluesky is really taking off with STEM academics across UCL, so I thought it was time we had our own Starter Pack
#academicsky #chemsky #stem #sciencesky #research #chemeng
go.bsky.app/9ZnMnCd
#academicsky #chemsky #stem #sciencesky #research #chemeng
go.bsky.app/9ZnMnCd
Looking forward to a seminar this Thursday (9 Nov) from Xavier Salvatella, IRB Barcelona:
“Kinetic stabilization of translation-repression condensates by a neuron-specific microexon”.
Gavin de Beer LT, Anatomy Building, UCL, 1-2pm.
#NMRchat 🧪
“Kinetic stabilization of translation-repression condensates by a neuron-specific microexon”.
Gavin de Beer LT, Anatomy Building, UCL, 1-2pm.
#NMRchat 🧪
November 7, 2023 at 4:11 PM
Looking forward to a seminar this Thursday (9 Nov) from Xavier Salvatella, IRB Barcelona:
“Kinetic stabilization of translation-repression condensates by a neuron-specific microexon”.
Gavin de Beer LT, Anatomy Building, UCL, 1-2pm.
#NMRchat 🧪
“Kinetic stabilization of translation-repression condensates by a neuron-specific microexon”.
Gavin de Beer LT, Anatomy Building, UCL, 1-2pm.
#NMRchat 🧪
Looking forward to presenting this beautiful paper from Uli Hommel and colleagues at Novartis as a case study in biomolecular NMR to our MSc Drug Discovery students this afternoon. 🧪 #NMR
Discovery of a selective and biologically active low-molecular weight antagonist of human interleuki...
Interleukin-1β is a pro-inflammatory cytokine of medical importance. Here the authors describe the discovery of a low-molecular weight compound that antagonizes hIL-1β function in cells, demonstrati...
www.nature.com
October 20, 2023 at 11:21 AM
Looking forward to presenting this beautiful paper from Uli Hommel and colleagues at Novartis as a case study in biomolecular NMR to our MSc Drug Discovery students this afternoon. 🧪 #NMR
Reposted by Chris Waudby
In Science this week, Rafal Klajn and collaborators use visible light and spatial constraints to build up the disfavored azobenzene isomer
Chemsky 🧪
www.science.org/doi/full/10....
Chemsky 🧪
www.science.org/doi/full/10....
Science | AAAS
www.science.org
September 21, 2023 at 6:13 PM
In Science this week, Rafal Klajn and collaborators use visible light and spatial constraints to build up the disfavored azobenzene isomer
Chemsky 🧪
www.science.org/doi/full/10....
Chemsky 🧪
www.science.org/doi/full/10....
Disgusted by the UK government’s abandonment of its climate policy? Turn your anger into something more positive:
1. Sign your lab up to LEAF www.ucl.ac.uk/sustainable/...
2. Pledge to take trains over planes
3. Embed sustainability in your teaching
4. Vote!
#AcademicSky 🧪
1. Sign your lab up to LEAF www.ucl.ac.uk/sustainable/...
2. Pledge to take trains over planes
3. Embed sustainability in your teaching
4. Vote!
#AcademicSky 🧪
LEAF - Laboratory Efficiency Assessment Framework
LEAF is a standard set by UCL to improve the sustainability and efficiency of laboratories. Join the 85 global institutions already taking part and help address the climate and ecological emergencies
www.ucl.ac.uk
September 21, 2023 at 7:38 AM
Disgusted by the UK government’s abandonment of its climate policy? Turn your anger into something more positive:
1. Sign your lab up to LEAF www.ucl.ac.uk/sustainable/...
2. Pledge to take trains over planes
3. Embed sustainability in your teaching
4. Vote!
#AcademicSky 🧪
1. Sign your lab up to LEAF www.ucl.ac.uk/sustainable/...
2. Pledge to take trains over planes
3. Embed sustainability in your teaching
4. Vote!
#AcademicSky 🧪
Hello 👋 I’m Chris, an NMR spectroscopist and protein chemist at UCL interested in protein (mis)folding and glycan quality control, as well as NMR method and software development (big fan of #julialang). May also post cute photos of our dog. More at waudbylab.org. chemsky #AcademicSky #LGBTSTEM 🧪
The Waudby Group
waudbylab.org
September 20, 2023 at 9:40 AM
Hello 👋 I’m Chris, an NMR spectroscopist and protein chemist at UCL interested in protein (mis)folding and glycan quality control, as well as NMR method and software development (big fan of #julialang). May also post cute photos of our dog. More at waudbylab.org. chemsky #AcademicSky #LGBTSTEM 🧪