Christman Lab
@christmanlab.bsky.social
Lab of Prof. Karen L. Christman, Prof. of Bioeng'g and Assoc. Dean for Faculty, Co-Director Sanford Advanced Therapy Center, UC San Diego; co-EIC npj Regenerative Medicine
https://christman.ucsd.edu
https://christman.ucsd.edu
Reposted by Christman Lab
Why is #NIHfunding critical to early-stage clinical research? @ucsandiego.bsky.social #bioengineering professor Karen Christman explains.
Biomaterials from the @christmanlab.bsky.social are in clinical trials to heal heart conditions, from heart attacks to congenital defects.
Biomaterials from the @christmanlab.bsky.social are in clinical trials to heal heart conditions, from heart attacks to congenital defects.
July 8, 2025 at 1:07 AM
Why is #NIHfunding critical to early-stage clinical research? @ucsandiego.bsky.social #bioengineering professor Karen Christman explains.
Biomaterials from the @christmanlab.bsky.social are in clinical trials to heal heart conditions, from heart attacks to congenital defects.
Biomaterials from the @christmanlab.bsky.social are in clinical trials to heal heart conditions, from heart attacks to congenital defects.
Reposted by Christman Lab
AIMBE has launched our new Citizen Advocate for Science Letter: takeaction.io/aimbe/scienc...
We ask the broader scientific community to widely share this letter (✍️ <1 minute) with friends, family, and other concerned citizens to urge their elected officials to protect biomedical research funding 👇
We ask the broader scientific community to widely share this letter (✍️ <1 minute) with friends, family, and other concerned citizens to urge their elected officials to protect biomedical research funding 👇
Write Your Lawmakers - AIMBE
aimbe.org
June 20, 2025 at 6:34 PM
AIMBE has launched our new Citizen Advocate for Science Letter: takeaction.io/aimbe/scienc...
We ask the broader scientific community to widely share this letter (✍️ <1 minute) with friends, family, and other concerned citizens to urge their elected officials to protect biomedical research funding 👇
We ask the broader scientific community to widely share this letter (✍️ <1 minute) with friends, family, and other concerned citizens to urge their elected officials to protect biomedical research funding 👇
Reposted by Christman Lab
Reposted by Christman Lab
The latest tissue we are tackling is the mammary gland
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Volumetric printed biomimetic scaffolds support in vitro lactation of human milk-derived mammary epithelial cells
3D-printed breast tissue models pave the way for cutting-edge lactation research.
www.science.org
June 9, 2025 at 2:40 PM
The latest tissue we are tackling is the mammary gland
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Christman Lab
The astounding contribution of US academic science to new medicines
www.statnews.com/2025/06/06/u...
www.statnews.com/2025/06/06/u...
We set out to quantify U.S. academic contributions to medicines. The results stunned even us
From 2020 to 2024, universities contributed patents underpinning 50% of FDA-approved drugs. 87% of those academic breakthroughs came from American institutions.
www.statnews.com
June 7, 2025 at 6:04 PM
The astounding contribution of US academic science to new medicines
www.statnews.com/2025/06/06/u...
www.statnews.com/2025/06/06/u...
Reposted by Christman Lab
Huge congrats to Brandon Vogt & friends on our on Science Advances @science.org paper!!! We leveraged hydrogel biomaterials & AI tools from Dean Ho’s lab at NUS to determine sex-dependent drug combinations that target valve myofibroblasts! 🎯
www.science.org/doi/10.1126/...
@jacobsschool.bsky.social
www.science.org/doi/10.1126/...
@jacobsschool.bsky.social
June 7, 2025 at 1:26 AM
Huge congrats to Brandon Vogt & friends on our on Science Advances @science.org paper!!! We leveraged hydrogel biomaterials & AI tools from Dean Ho’s lab at NUS to determine sex-dependent drug combinations that target valve myofibroblasts! 🎯
www.science.org/doi/10.1126/...
@jacobsschool.bsky.social
www.science.org/doi/10.1126/...
@jacobsschool.bsky.social
Reposted by Christman Lab
Congratulations Professor Shi (@stimulatedraman.bsky.social) for your outstanding work imaging diseased tissue. Your contributions will no doubt lead to life-saving cures. Our gratitude to you!
today.ucsd.edu/story/a-clea...
today.ucsd.edu/story/a-clea...
A Clearer Look at Diabetic Kidney Disease via New Optical Imaging Technology
Researchers have developed a powerful new way to look inside kidney tissues, without needing to stain or damage the tissue samples. The new technique reveals early signs of disease often missed by tra...
today.ucsd.edu
June 2, 2025 at 2:58 PM
Congratulations Professor Shi (@stimulatedraman.bsky.social) for your outstanding work imaging diseased tissue. Your contributions will no doubt lead to life-saving cures. Our gratitude to you!
today.ucsd.edu/story/a-clea...
today.ucsd.edu/story/a-clea...
Reposted by Christman Lab
Could be huge. Especially for those terminated in the anti-DEI purge.
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
NOT-OD-25-115: Notice of Temporary Policy Exception to NIH Grants Policy Statement (NIHGPS) Section 12.3.7 to Permit Continued Eligibility for Mentored Career Development Award When an Award Ended Ear...
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Policy Exception to NIH Grants Policy Statement (NIHGPS) Section 12.3.7 to Permit Continued Eligibi...
grants.nih.gov
May 28, 2025 at 10:56 PM
Could be huge. Especially for those terminated in the anti-DEI purge.
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
"...NIH will allow individuals whose mentored career development awards prematurely ended on or after January 1, 2025, to be eligible to apply for a new mentored career development award"
grants.nih.gov/grants/guide...
Reposted by Christman Lab
🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
May 21, 2025 at 5:39 PM
🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Already 14,000+ public comments, deadline is Friday
📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful
Speak up! shorturl.at/WKuBj
Reposted by Christman Lab
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
May 18, 2025 at 10:44 PM
Northwestern has not received any NIH funds since March. No written communication about why or what can be done. Thank you Ben Singer for raising awareness at #ATS2025
Reposted by Christman Lab
The 80-year recipe stoking America’s Prosperity:
1) Free-market capital investments in brilliant ideas…
2) enabled by Engineering Innovations…
3) based on Science Research in Universities…
4) funded by Grants from the US Government.
It’s time more people understood this.
1) Free-market capital investments in brilliant ideas…
2) enabled by Engineering Innovations…
3) based on Science Research in Universities…
4) funded by Grants from the US Government.
It’s time more people understood this.
May 17, 2025 at 1:36 PM
The 80-year recipe stoking America’s Prosperity:
1) Free-market capital investments in brilliant ideas…
2) enabled by Engineering Innovations…
3) based on Science Research in Universities…
4) funded by Grants from the US Government.
It’s time more people understood this.
1) Free-market capital investments in brilliant ideas…
2) enabled by Engineering Innovations…
3) based on Science Research in Universities…
4) funded by Grants from the US Government.
It’s time more people understood this.
Reposted by Christman Lab
"For me, the answer now lies in refusal, the withdrawal of participation from systems that require dishonesty as the price of belonging."
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Why I’m Resigning from the NSF and Library of Congress
I cannot participate in systems that require dishonesty as the price of belonging.
time.com
May 13, 2025 at 11:19 AM
"For me, the answer now lies in refusal, the withdrawal of participation from systems that require dishonesty as the price of belonging."
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Today I am resigning from the National Science Board and the Library of Congress Scholars Council.
I wrote about my decision in TIME.
time.com/7285045/resi...
Reposted by Christman Lab
Well this is truly insane...
Exclusive: National Science Foundation staff were told today that the agency’s 37 divisions—across all eight directorates—are being abolished and the number of programs within those divisions will be drastically reduced.
Exclusive: NSF faces radical shake-up as officials abolish its 37 divisions
Changes seen as a response to presidential directives on what research to fund
scim.ag
May 9, 2025 at 12:09 AM
Well this is truly insane...
Reposted by Christman Lab
One of grants frozen at Cornell: $6.7M (4 yrs) to develop heart pumps for babies born w/ heart defects.
It took decades of work to get to point of prepping device for in-human clinical trials. No private company could do this.
The cruelty of the Trump administration is heartbreaking. So to speak.
It took decades of work to get to point of prepping device for in-human clinical trials. No private company could do this.
The cruelty of the Trump administration is heartbreaking. So to speak.
Research at risk: Life-saving heart pumps for babies | Cornell Chronicle
After receiving a stop-work order from the federal government, the future of a device to help children with heart defects is uncertain.
news.cornell.edu
May 7, 2025 at 11:56 AM
One of grants frozen at Cornell: $6.7M (4 yrs) to develop heart pumps for babies born w/ heart defects.
It took decades of work to get to point of prepping device for in-human clinical trials. No private company could do this.
The cruelty of the Trump administration is heartbreaking. So to speak.
It took decades of work to get to point of prepping device for in-human clinical trials. No private company could do this.
The cruelty of the Trump administration is heartbreaking. So to speak.
Reposted by Christman Lab
🚨 AIMBE is calling on the biomedical research community to take a minute to send our 3 new advocacy letters urging Congress to:
1. Protect the STEM Training Pipeline (e.g., NIH MOSAIC, T32s, MARC, etc.)
2. Oppose Indirect Cost Caps
3. Support Research Funding in FY2026
aimbe.org/advocate/wri...
1. Protect the STEM Training Pipeline (e.g., NIH MOSAIC, T32s, MARC, etc.)
2. Oppose Indirect Cost Caps
3. Support Research Funding in FY2026
aimbe.org/advocate/wri...
May 5, 2025 at 6:34 PM
🚨 AIMBE is calling on the biomedical research community to take a minute to send our 3 new advocacy letters urging Congress to:
1. Protect the STEM Training Pipeline (e.g., NIH MOSAIC, T32s, MARC, etc.)
2. Oppose Indirect Cost Caps
3. Support Research Funding in FY2026
aimbe.org/advocate/wri...
1. Protect the STEM Training Pipeline (e.g., NIH MOSAIC, T32s, MARC, etc.)
2. Oppose Indirect Cost Caps
3. Support Research Funding in FY2026
aimbe.org/advocate/wri...
Great work with our long time collaborator Nathan Gianneschi, PhD on a new minimally invasive treatment strategy for acute myocardial infarction with implication for other inflammatory and ischemic conditions. Our outstanding former PhD students Josh Mesfin and Kendal Carrow, PhD led the work.
This injected, protein-like polymer helps tissues heal after a #heartattack: work by @ucsandiego.bsky.social @christmanlab.bsky.social & Northwestern: today.ucsd.edu/story/this-i...
#bioengineering #heartfailure #engineeringinmedicine
#bioengineering #heartfailure #engineeringinmedicine
This Injected Protein-like Polymer Helps Tissues Heal After a Heart Attack
Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encou...
today.ucsd.edu
April 28, 2025 at 6:36 PM
Great work with our long time collaborator Nathan Gianneschi, PhD on a new minimally invasive treatment strategy for acute myocardial infarction with implication for other inflammatory and ischemic conditions. Our outstanding former PhD students Josh Mesfin and Kendal Carrow, PhD led the work.
Reposted by Christman Lab
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
April 28, 2025 at 5:20 PM
Deaths from heart disease down 75%, that’s NIH.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Deaths from stroke down 75%, that’s NIH.
HIV/AIDS no longer a death sentence, that’s NIH.
99% of FDA approved drugs in the last decade, that’s NIH.
Please show this video to anyone who doesn’t understand why the NIH is so important.
Reposted by Christman Lab
Big milestone for the Cyphert lab - check out our first publication in npj Antimicrobials and Resistance! This paper was led by a team of amazing grad students: Tanya, Aryak, and Yumie and undergraduates Julie, Arlene, and Sidhant. @jacobsschool.bsky.social #newPI www.nature.com/articles/s44...
Leveraging the microbiome to combat antibiotic resistant gynecological infections
npj Antimicrobials and Resistance - Leveraging the microbiome to combat antibiotic resistant gynecological infections
www.nature.com
April 23, 2025 at 8:29 PM
Big milestone for the Cyphert lab - check out our first publication in npj Antimicrobials and Resistance! This paper was led by a team of amazing grad students: Tanya, Aryak, and Yumie and undergraduates Julie, Arlene, and Sidhant. @jacobsschool.bsky.social #newPI www.nature.com/articles/s44...
Reposted by Christman Lab
Congratulations to #computerscience Professor Ryan Kastner, honored for exceptional undergraduate mentorship by there Computing Research Association! This is a first for @ucsandiego.bsky.social!
Kastner is also a @qi-ucsd.bsky.social affiliate.
today.ucsd.edu/story/comput...
Kastner is also a @qi-ucsd.bsky.social affiliate.
today.ucsd.edu/story/comput...
Computer Science Professor Earns Undergraduate Mentorship Award for Going the Extra Mile, Literally
Ryan Kastner, a professor in the Jacobs School of Engineering’s Department of Computer Science and Engineering, recently received the prestigious award for undergraduate research faculty mentoring fro...
today.ucsd.edu
April 25, 2025 at 12:31 AM
Congratulations to #computerscience Professor Ryan Kastner, honored for exceptional undergraduate mentorship by there Computing Research Association! This is a first for @ucsandiego.bsky.social!
Kastner is also a @qi-ucsd.bsky.social affiliate.
today.ucsd.edu/story/comput...
Kastner is also a @qi-ucsd.bsky.social affiliate.
today.ucsd.edu/story/comput...
Reposted by Christman Lab
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 6:03 PM
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Reposted by Christman Lab
POV: Plenary lecture at the Society For Biomaterials - definitely my best SFB selfie yet! 📸 Thank you to the SFB community for the 2025 Young Investigator Award - my lab is committed to our mission to understand sex chromosome biology & develop better treatments for all! @jacobsschool.bsky.social
April 11, 2025 at 2:27 PM
POV: Plenary lecture at the Society For Biomaterials - definitely my best SFB selfie yet! 📸 Thank you to the SFB community for the 2025 Young Investigator Award - my lab is committed to our mission to understand sex chromosome biology & develop better treatments for all! @jacobsschool.bsky.social
Reposted by Christman Lab
Next week, I will be at Humanities Unlocking Biomaterials' inaugural meeting and 50th Annual Meeting of Society For Biomaterials in Chicago! Come meet me to discuss your work and learn about Cell Biomaterials!
#HUB, #SFB, #Biomaterials
#HUB, #SFB, #Biomaterials
April 3, 2025 at 8:25 PM
Next week, I will be at Humanities Unlocking Biomaterials' inaugural meeting and 50th Annual Meeting of Society For Biomaterials in Chicago! Come meet me to discuss your work and learn about Cell Biomaterials!
#HUB, #SFB, #Biomaterials
#HUB, #SFB, #Biomaterials
Reposted by Christman Lab
On a letter I signed
www.nytimes.com/2025/03/31/s...
www.nytimes.com/2025/03/31/s...
Trump Administration Has Begun a War on Science, Researchers Say (Gift Article)
Nearly 2,000 scientists urged that Congress restore funding to federal agencies decimated by recent cuts.
www.nytimes.com
March 31, 2025 at 4:08 PM
On a letter I signed
www.nytimes.com/2025/03/31/s...
www.nytimes.com/2025/03/31/s...
Reposted by Christman Lab
As I was saying #RFKJr, #Trump, #Musk and #Vought are intent on destroying science, public health and healthcare in America.
🚨 Over 70 graduate programs in the biological and biomedical sciences have frozen or slashed admissions.
The consequences are profound—how many brilliant minds are being shut out of research entirely? How much future discovery is being lost before it even begins?
docs.google.com/spreadsheets...
The consequences are profound—how many brilliant minds are being shut out of research entirely? How much future discovery is being lost before it even begins?
docs.google.com/spreadsheets...
Graduate Reductions Across Biomedical Sciences (2025)
docs.google.com
March 29, 2025 at 7:40 AM