Maggie Chen
@chenmaggiesy.bsky.social
Reposted by Maggie Chen
New preprint from our lab!
What can we learn about the properties of gene regulatory elements by CRISPR’ing a random set of accessible sites in human cells?
Find out here: www.biorxiv.org/content/10.1...
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1/
What can we learn about the properties of gene regulatory elements by CRISPR’ing a random set of accessible sites in human cells?
Find out here: www.biorxiv.org/content/10.1...
👇
1/
September 19, 2025 at 3:03 AM
New preprint from our lab!
What can we learn about the properties of gene regulatory elements by CRISPR’ing a random set of accessible sites in human cells?
Find out here: www.biorxiv.org/content/10.1...
👇
1/
What can we learn about the properties of gene regulatory elements by CRISPR’ing a random set of accessible sites in human cells?
Find out here: www.biorxiv.org/content/10.1...
👇
1/
Reposted by Maggie Chen
Excited for a major milestone in our efforts to map enhancers and interpret variants in the human genome:
The E2G Portal! e2g.stanford.edu
This collates our predictions of enhancer-gene regulatory interactions across >1,600 cell types and tissues.
Uses cases 👇
1/
The E2G Portal! e2g.stanford.edu
This collates our predictions of enhancer-gene regulatory interactions across >1,600 cell types and tissues.
Uses cases 👇
1/
September 18, 2025 at 4:14 PM
Excited for a major milestone in our efforts to map enhancers and interpret variants in the human genome:
The E2G Portal! e2g.stanford.edu
This collates our predictions of enhancer-gene regulatory interactions across >1,600 cell types and tissues.
Uses cases 👇
1/
The E2G Portal! e2g.stanford.edu
This collates our predictions of enhancer-gene regulatory interactions across >1,600 cell types and tissues.
Uses cases 👇
1/
nothing like when your brilliant wonderful high school science fair partner-in-crime publishes a fascinating scientific story!! Congratulations Liana!! 🧬
(1/7) Very excited to share my first PhD preprint on the interactions of two of my favorite mobile genetic elements: phages and group II introns!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Prevalence of Group II Introns in Phage Genomes
Although bacteriophage genomes are under strong selective pressure for high coding density, they are still frequently invaded by mobile genetic elements (MGEs). Group II introns are MGEs that reduce h...
www.biorxiv.org
May 24, 2025 at 7:33 PM
nothing like when your brilliant wonderful high school science fair partner-in-crime publishes a fascinating scientific story!! Congratulations Liana!! 🧬
Reposted by Maggie Chen
This news is hot off the press! We are so excited to present the 2025 #MassMediaFellows! These 17 scientists will spend their summer writing, reporting, and working on their #SciComm skills in news outlets across the country! Learn more about the #MMF50th class here: www.aaas.org/news/aaas-ma...
April 24, 2025 at 5:15 PM
This news is hot off the press! We are so excited to present the 2025 #MassMediaFellows! These 17 scientists will spend their summer writing, reporting, and working on their #SciComm skills in news outlets across the country! Learn more about the #MMF50th class here: www.aaas.org/news/aaas-ma...
Reposted by Maggie Chen
Our latest work now online in Cell:
Rewriting regulatory DNA to dissect and reprogram gene expression
Our new method (Variant-EFFECTS) uses high-throughput prime editing + flow sorting + sequencing to precisely measure effects of noncoding variants on gene expression
Thread 👇
Rewriting regulatory DNA to dissect and reprogram gene expression
Our new method (Variant-EFFECTS) uses high-throughput prime editing + flow sorting + sequencing to precisely measure effects of noncoding variants on gene expression
Thread 👇
April 17, 2025 at 6:26 PM
Our latest work now online in Cell:
Rewriting regulatory DNA to dissect and reprogram gene expression
Our new method (Variant-EFFECTS) uses high-throughput prime editing + flow sorting + sequencing to precisely measure effects of noncoding variants on gene expression
Thread 👇
Rewriting regulatory DNA to dissect and reprogram gene expression
Our new method (Variant-EFFECTS) uses high-throughput prime editing + flow sorting + sequencing to precisely measure effects of noncoding variants on gene expression
Thread 👇
Reposted by Maggie Chen
I am elated to share that our manuscript describing Variant-EFFECTS, a high-throughput technology we developed to precisely and quantitatively measure the effects of CRISPR-mediated edits on gene expression, is now published at @cellpress.bsky.social: authors.elsevier.com/c/1kxgiL7PXu...
authors.elsevier.com
April 17, 2025 at 6:20 PM
I am elated to share that our manuscript describing Variant-EFFECTS, a high-throughput technology we developed to precisely and quantitatively measure the effects of CRISPR-mediated edits on gene expression, is now published at @cellpress.bsky.social: authors.elsevier.com/c/1kxgiL7PXu...
Reposted by Maggie Chen
As graduate programs lose spots and labs face shutdowns following Trump administration cuts to science funding, students and researchers are left to figure out what's next.
The Chaos of NIH Cuts Has Left Early-Career Scientists Scrambling
As graduate programs lose spots and labs face shutdowns following Trump administration cuts to science funding, students and researchers are left to figure out what's next.
wrd.cm
March 24, 2025 at 10:49 AM
As graduate programs lose spots and labs face shutdowns following Trump administration cuts to science funding, students and researchers are left to figure out what's next.