Charles de Bock
@charles-debock.bsky.social
Cancer Researcher #bloodcancer #leukemia #functionalgenomics #TCellLeukemia. Group Leader at Children's Cancer Institute, Sydney. https://bit.ly/3zxhpW6
A wonderful discussion with Anika Sijs-Szabó from Erasmus MC and Leiden University Medical Center and Roger Mulet Lazaro from Erasmus MC on their work improving the classification of #ALAL cases published in @hemasphere-journal.bsky.social .
Tune in to find out how collaboration fuels discovery!
Tune in to find out how collaboration fuels discovery!
Sneak peek of the next podcast episode!
Host Dr Charles de Bock chats with Aniko Sijs-Szabo and Roger Mulet-Lázaro, co-authors of "Transcriptional profiling directs the classification of acute leukemias of ambiguous lineage into AML, B-ALL or T-ALL"
Host Dr Charles de Bock chats with Aniko Sijs-Szabo and Roger Mulet-Lázaro, co-authors of "Transcriptional profiling directs the classification of acute leukemias of ambiguous lineage into AML, B-ALL or T-ALL"
November 1, 2025 at 9:48 PM
A wonderful discussion with Anika Sijs-Szabó from Erasmus MC and Leiden University Medical Center and Roger Mulet Lazaro from Erasmus MC on their work improving the classification of #ALAL cases published in @hemasphere-journal.bsky.social .
Tune in to find out how collaboration fuels discovery!
Tune in to find out how collaboration fuels discovery!
Another great conversation on NUP98-rearranged #AML and the use of #Menin inhibitors. Plus some hot tips on how to measure cytotoxicity in co-culture systems and finally, how to pronounce #MEIS1. Listen below and subscribe where ever you get your podcasts from @hemasphere-journal.bsky.social
🎙️New Episode!
Dr Charles de Bock hosts Prof Michel Zwaan and Prof Olaf Heidenreich, two co-authors from the 2025 HemaSphere Award - Top Cited: Biology paper "The MLL-Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML." 🎧 https://bit.ly/3HJbmr6
Dr Charles de Bock hosts Prof Michel Zwaan and Prof Olaf Heidenreich, two co-authors from the 2025 HemaSphere Award - Top Cited: Biology paper "The MLL-Menin Interaction is a Therapeutic Vulnerability in NUP98-rearranged AML." 🎧 https://bit.ly/3HJbmr6
September 5, 2025 at 10:41 AM
Another great conversation on NUP98-rearranged #AML and the use of #Menin inhibitors. Plus some hot tips on how to measure cytotoxicity in co-culture systems and finally, how to pronounce #MEIS1. Listen below and subscribe where ever you get your podcasts from @hemasphere-journal.bsky.social
Reposted by Charles de Bock
🎧REPLAY!
In this episode host Dr Charles de Bock discusses the role of mouse models in understanding leukemogenesis & hematopoiesis w/ Prof Richard Lock: https://bit.ly/40Ch3NP
Listen & enjoy casual, insightful discussions about #hematology research.
In this episode host Dr Charles de Bock discusses the role of mouse models in understanding leukemogenesis & hematopoiesis w/ Prof Richard Lock: https://bit.ly/40Ch3NP
Listen & enjoy casual, insightful discussions about #hematology research.
August 22, 2025 at 11:24 AM
🎧REPLAY!
In this episode host Dr Charles de Bock discusses the role of mouse models in understanding leukemogenesis & hematopoiesis w/ Prof Richard Lock: https://bit.ly/40Ch3NP
Listen & enjoy casual, insightful discussions about #hematology research.
In this episode host Dr Charles de Bock discusses the role of mouse models in understanding leukemogenesis & hematopoiesis w/ Prof Richard Lock: https://bit.ly/40Ch3NP
Listen & enjoy casual, insightful discussions about #hematology research.
Reposted by Charles de Bock
We are honoured to welcome Professor John D. Crispino, from
@stjude.bsky.social as speaker to #NDLR2026. John’s research focuses on mechanisms of #Leukemia development in children with Down syndrome and the malignant progression of #MyelodysplasticSyndrome and #MyeloproliferativeNeoplasms.
@stjude.bsky.social as speaker to #NDLR2026. John’s research focuses on mechanisms of #Leukemia development in children with Down syndrome and the malignant progression of #MyelodysplasticSyndrome and #MyeloproliferativeNeoplasms.
August 19, 2025 at 11:55 PM
We are honoured to welcome Professor John D. Crispino, from
@stjude.bsky.social as speaker to #NDLR2026. John’s research focuses on mechanisms of #Leukemia development in children with Down syndrome and the malignant progression of #MyelodysplasticSyndrome and #MyeloproliferativeNeoplasms.
@stjude.bsky.social as speaker to #NDLR2026. John’s research focuses on mechanisms of #Leukemia development in children with Down syndrome and the malignant progression of #MyelodysplasticSyndrome and #MyeloproliferativeNeoplasms.
Reposted by Charles de Bock
The NIC welcomes speakers Hanna Mikkola and Elizabeth Ng who will present their latest research on stem cell development and regeneration at the 20 August webinar on Human HSC Ontogeny. Register now www.iseh.org/ISEHWebinars
July 31, 2025 at 9:01 PM
The NIC welcomes speakers Hanna Mikkola and Elizabeth Ng who will present their latest research on stem cell development and regeneration at the 20 August webinar on Human HSC Ontogeny. Register now www.iseh.org/ISEHWebinars
So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.
HemaSphere Podcast
Medicine Podcast · Updated Monthly · HemaSphere is the official online, open access journal of the European Hematology Association (EHA). HemaSphere publishes exciting basic, translational, and clinic...
podcasts.apple.com
August 1, 2025 at 5:01 AM
So the latest @hemasphere-journal.bsky.social Podcast is out! This time all about Metabolism. You can subscribe podcasts.apple.com/au/podcast/h... to get all the podcasts direct into your feed. Each is around 30 min, perfect for that commute to work.
Reposted by Charles de Bock
I'm pleased to share that Leukemia have published our analysis of heterogeneous responses to hypomethylating agents #HMAs in Acute Myeloid Leukaemia #AML
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal - Leukemia
Leukemia - Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for acute myeloid leukemia cell self-renewal
www.nature.com
July 28, 2025 at 8:10 PM
I'm pleased to share that Leukemia have published our analysis of heterogeneous responses to hypomethylating agents #HMAs in Acute Myeloid Leukaemia #AML
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Charles de Bock
This was very happy news to arrive to today! Thank you to our authors, reviewers, and readership for your continued support. We are glad to know that everyone's hard work is well-appreciated.
Exciting to share the new impact factor of @hemasphere-journal.bsky.social, the #openaccess journal of the European Hematology Association (EHA).
The 2024 Journal Impact Factor is 14.6 - ranking as number 5 of 99 hematology journals (Source: Journal Citations Reports, Clarivate).
The 2024 Journal Impact Factor is 14.6 - ranking as number 5 of 99 hematology journals (Source: Journal Citations Reports, Clarivate).
June 18, 2025 at 3:47 PM
This was very happy news to arrive to today! Thank you to our authors, reviewers, and readership for your continued support. We are glad to know that everyone's hard work is well-appreciated.
Reposted by Charles de Bock
🚨Today! @ 15:45, MiCo room CORAL 6
We warmly invite you to the HemaSphere Scientific Session where we will dive into 3 of our exciting + cutting-edge biology publications. Hope to see you there!
🕰️: 15:45 - 16:45
📍: Room CORAL 6, #EHA2025
🎤: https://bit.ly/4koLwXk
We warmly invite you to the HemaSphere Scientific Session where we will dive into 3 of our exciting + cutting-edge biology publications. Hope to see you there!
🕰️: 15:45 - 16:45
📍: Room CORAL 6, #EHA2025
🎤: https://bit.ly/4koLwXk
June 14, 2025 at 10:02 AM
🚨Today! @ 15:45, MiCo room CORAL 6
We warmly invite you to the HemaSphere Scientific Session where we will dive into 3 of our exciting + cutting-edge biology publications. Hope to see you there!
🕰️: 15:45 - 16:45
📍: Room CORAL 6, #EHA2025
🎤: https://bit.ly/4koLwXk
We warmly invite you to the HemaSphere Scientific Session where we will dive into 3 of our exciting + cutting-edge biology publications. Hope to see you there!
🕰️: 15:45 - 16:45
📍: Room CORAL 6, #EHA2025
🎤: https://bit.ly/4koLwXk
Reposted by Charles de Bock
Don’t miss the second YERM Session on „New insights into clonal hematopoiesis“ at 10 o‘clock in Brown Hall 2!
#EHA2025 #YoungEHA #Hematology
#EHA2025 #YoungEHA #Hematology
June 14, 2025 at 7:42 AM
Don’t miss the second YERM Session on „New insights into clonal hematopoiesis“ at 10 o‘clock in Brown Hall 2!
#EHA2025 #YoungEHA #Hematology
#EHA2025 #YoungEHA #Hematology
The team representing @kidscancerinst.bsky.social at #EHA2025 @hansenjk.bsky.social Faezeh Khalili, Jackie Huang, Yashna Walia
June 12, 2025 at 5:00 PM
The team representing @kidscancerinst.bsky.social at #EHA2025 @hansenjk.bsky.social Faezeh Khalili, Jackie Huang, Yashna Walia
Reposted by Charles de Bock
We are HemaSphere proud at #EHA2025, where 2 of our editors received special EHA awards! Congrats to Jan Cools, Ed in Chief, for the education & mentoring award; and to Mandy Lauw, Scientific Ed, for the YoungEHA award. Well deserved 👏 @jancools.bsky.social @mandylauw.bsky.social
June 12, 2025 at 12:41 PM
We are HemaSphere proud at #EHA2025, where 2 of our editors received special EHA awards! Congrats to Jan Cools, Ed in Chief, for the education & mentoring award; and to Mandy Lauw, Scientific Ed, for the YoungEHA award. Well deserved 👏 @jancools.bsky.social @mandylauw.bsky.social
Honoured to have been a mentee of @jancools.bsky.social who is this years #EHA2025 Education and Mentoring award winner. Amazing and recognising his unwavering support for so many researchers!
June 12, 2025 at 10:45 AM
Honoured to have been a mentee of @jancools.bsky.social who is this years #EHA2025 Education and Mentoring award winner. Amazing and recognising his unwavering support for so many researchers!
Reposted by Charles de Bock
Dr C de Bock hosts co-authors Dr F Fioredda & Dr E Papadaki to discuss Guidelines for treating neutropenias. Delve into the importance of international guidelines, challenges ➕ more. 🎧 https://bit.ly/42O9l4v.
Part 1: 2023 neutropenia Guidelines, diagnosis &management #2025HemaSphereAward winner 🏆
Part 1: 2023 neutropenia Guidelines, diagnosis &management #2025HemaSphereAward winner 🏆
June 12, 2025 at 8:03 AM
Dr C de Bock hosts co-authors Dr F Fioredda & Dr E Papadaki to discuss Guidelines for treating neutropenias. Delve into the importance of international guidelines, challenges ➕ more. 🎧 https://bit.ly/42O9l4v.
Part 1: 2023 neutropenia Guidelines, diagnosis &management #2025HemaSphereAward winner 🏆
Part 1: 2023 neutropenia Guidelines, diagnosis &management #2025HemaSphereAward winner 🏆
Next up is Dr Hansen Kosasih @hansenjk.bsky.social looking at cis-regulome of AKR1C3 which activates super prodrug ACHM-025 and can eradicate T-ALL. He is speaking today at #EHA2025 molecular Hematopoiesis workshop. Plus poster PS1332 @kidscancerinst.bsky.social
June 12, 2025 at 8:26 AM
Next up is Dr Hansen Kosasih @hansenjk.bsky.social looking at cis-regulome of AKR1C3 which activates super prodrug ACHM-025 and can eradicate T-ALL. He is speaking today at #EHA2025 molecular Hematopoiesis workshop. Plus poster PS1332 @kidscancerinst.bsky.social
For #EHA2025 our group has Phd Candidate Yashna Walia doing in vivo PDX dual gRNA screen of epigenetic regions looking into GR resistance. Check out Poster PS1334 @kidscancerinst.bsky.social
June 12, 2025 at 7:56 AM
For #EHA2025 our group has Phd Candidate Yashna Walia doing in vivo PDX dual gRNA screen of epigenetic regions looking into GR resistance. Check out Poster PS1334 @kidscancerinst.bsky.social
Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!
June 12, 2025 at 5:25 AM
Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!
Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!
June 12, 2025 at 5:24 AM
Hello #EHA2025. Happy to be here with my group this week. Connecting with old friends and colleagues and making new friends this week. Let me know if you are around!
Looking forward to attend the #EHA2025 @hemasphere-journal.bsky.social sessions next week!
Attention fundamental #hematology researchers: we warmly invite you to the HemaSphere Scientific Session at #EHA2025.
Dive into 3 of our exciting + cutting-edge biology publications. Mark your cals & see you there!
📆: Saturday, June 14
🕰️: 15:45 - 16:45
📍: MiCo, Room CORAL 6
🎤: https://bit.ly/4koLwXk
Dive into 3 of our exciting + cutting-edge biology publications. Mark your cals & see you there!
📆: Saturday, June 14
🕰️: 15:45 - 16:45
📍: MiCo, Room CORAL 6
🎤: https://bit.ly/4koLwXk
June 8, 2025 at 6:35 AM
Looking forward to attend the #EHA2025 @hemasphere-journal.bsky.social sessions next week!
Reposted by Charles de Bock
Heading to #EHA2025 in Milan in 1.5(ish) weeks? HemaSphere has 2 exciting sessions on the program!
📌Peer Review Workshop: Fri 13 June, 13:30 - 15:00
💡Learn + master the peer review role/process
📌HemaSphere Scientific Session: Sat 14 June, 15:45 - 16:45
💡Dive into 3 of our cutting-edge biology papers
📌Peer Review Workshop: Fri 13 June, 13:30 - 15:00
💡Learn + master the peer review role/process
📌HemaSphere Scientific Session: Sat 14 June, 15:45 - 16:45
💡Dive into 3 of our cutting-edge biology papers
May 29, 2025 at 8:03 AM
Heading to #EHA2025 in Milan in 1.5(ish) weeks? HemaSphere has 2 exciting sessions on the program!
📌Peer Review Workshop: Fri 13 June, 13:30 - 15:00
💡Learn + master the peer review role/process
📌HemaSphere Scientific Session: Sat 14 June, 15:45 - 16:45
💡Dive into 3 of our cutting-edge biology papers
📌Peer Review Workshop: Fri 13 June, 13:30 - 15:00
💡Learn + master the peer review role/process
📌HemaSphere Scientific Session: Sat 14 June, 15:45 - 16:45
💡Dive into 3 of our cutting-edge biology papers
Reposted by Charles de Bock
This HemaTopic by Sci Ed C de Bock discusses using PDXs for testing leukemia therapies, focusing on PDX model maintenance, immunodeficient mice & standardized reporting for preclinical drug testing. It also ties in a recent HemaSphere podcast with Prof Richard Lock. See both👉
Patient‐derived xenografts: Practical considerations for preclinical drug testing
Click on the article title to read more.
bit.ly
May 16, 2025 at 8:30 AM
This HemaTopic by Sci Ed C de Bock discusses using PDXs for testing leukemia therapies, focusing on PDX model maintenance, immunodeficient mice & standardized reporting for preclinical drug testing. It also ties in a recent HemaSphere podcast with Prof Richard Lock. See both👉
Reposted by Charles de Bock
New Episode!
Dr. Charles De Bock hosts Prof Jan Cools, Prof Heidi Segers & Dr Margo Aertgeerts to discuss advancements in ALL treatment, challenges of relapse & innovative use of SCS to uncover genetic mutations & clonal composition. Listen to their insightful discussion 🎧 bit.ly/42N3cWx
Dr. Charles De Bock hosts Prof Jan Cools, Prof Heidi Segers & Dr Margo Aertgeerts to discuss advancements in ALL treatment, challenges of relapse & innovative use of SCS to uncover genetic mutations & clonal composition. Listen to their insightful discussion 🎧 bit.ly/42N3cWx
May 7, 2025 at 8:31 AM
New Episode!
Dr. Charles De Bock hosts Prof Jan Cools, Prof Heidi Segers & Dr Margo Aertgeerts to discuss advancements in ALL treatment, challenges of relapse & innovative use of SCS to uncover genetic mutations & clonal composition. Listen to their insightful discussion 🎧 bit.ly/42N3cWx
Dr. Charles De Bock hosts Prof Jan Cools, Prof Heidi Segers & Dr Margo Aertgeerts to discuss advancements in ALL treatment, challenges of relapse & innovative use of SCS to uncover genetic mutations & clonal composition. Listen to their insightful discussion 🎧 bit.ly/42N3cWx
Reposted by Charles de Bock
We are recruiting!! Ads now live for a Data Coordinator and 2 Research Assistants/biobankers to join a new @ludwigcancer.bsky.social - @imm.ox.ac.uk joint initiative to prevent progression from early- to advanced blood cancer. Joint posts with Adam Mead+others in Oxford Ludwig. Links below
March 27, 2025 at 7:59 AM
We are recruiting!! Ads now live for a Data Coordinator and 2 Research Assistants/biobankers to join a new @ludwigcancer.bsky.social - @imm.ox.ac.uk joint initiative to prevent progression from early- to advanced blood cancer. Joint posts with Adam Mead+others in Oxford Ludwig. Links below
Reposted by Charles de Bock
We have put together an amazing line-up of invited speakers and talks selected from abstracts for the 2nd Annual ISEH Mini-Symposium!!! Join us online on March 26th (free for ISEH members) to learn what’s new and exciting in Experimental Hematology!!! @isehsociety.bsky.social
March 20, 2025 at 11:55 AM
We have put together an amazing line-up of invited speakers and talks selected from abstracts for the 2nd Annual ISEH Mini-Symposium!!! Join us online on March 26th (free for ISEH members) to learn what’s new and exciting in Experimental Hematology!!! @isehsociety.bsky.social
Reposted by Charles de Bock
Huge congratulations to this incredible group!!! 👏👏👏
ISEH is thrilled to announce the recipients of the 2025 Society Awards, which will be presented at the ISEH 54th Annual Scientific Meeting. Read more about each award recipient on www.simplyblood.org
March 12, 2025 at 3:49 PM
Huge congratulations to this incredible group!!! 👏👏👏