Cenk Celik
@cenkcelik.bsky.social
Research Fellow at UCL Genetics Institute • Single-cell and spatial transcriptomics
Reposted by Cenk Celik
How do tissues organise, adapt, or collapse? 🧬
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
October 7, 2025 at 7:46 PM
How do tissues organise, adapt, or collapse? 🧬
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
We’re looking for a postdoc with strong quantitative skills to tackle these questions in a highly interdisciplinary project bridging spatial omics, ecology & mathematical modelling (expertise required in at least one topic).
Apply 👉 tinyurl.com/3d37d3st
Reposted by Cenk Celik
Come do some cool cell cycle science with the awesome @alexisbarr.bsky.social and me! 🔬✨
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
September 19, 2025 at 12:15 PM
Come do some cool cell cycle science with the awesome @alexisbarr.bsky.social and me! 🔬✨
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
We’re looking for an enthusiastic computational biologist / data scientist (4-year postdoc) to dive into loads of cancer genomics & transcriptomics data.
Details below. Please share!
Reposted by Cenk Celik
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Description
Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...
www.imperial.ac.uk
September 18, 2025 at 8:02 PM
@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Deadline 15th October. Get in touch if you have any questions.
Please repost!
More details:
www.imperial.ac.uk/jobs/search-...
Reposted by Cenk Celik
Feeling very fortunate to be awarded a Programme Foundation Award from CRUK @cruk-si.bsky.social
This is a new area for the lab & lets us team up with @mariasecrier.bsky.social to tackle a big problem of how different cancers lose control of proliferation
This is a new area for the lab & lets us team up with @mariasecrier.bsky.social to tackle a big problem of how different cancers lose control of proliferation
Congratulations to @alexisbarr.bsky.social and Jesus Gil who have received funding awards, together totalling around £3M, from @cancerresearchuk.org!
They will lead two exciting projects that could result in discoveries that make a real difference to the lives of people with cancer in the future.
They will lead two exciting projects that could result in discoveries that make a real difference to the lives of people with cancer in the future.
LMS scientists receive funding to boost cancer research
Cancer Research UK has awarded significant funding to researchers at the MRC Laboratory of Medical Sciences (LMS) to lead two exciting new projects that could result in discoveries that make a real di...
lms.mrc.ac.uk
September 3, 2025 at 6:18 PM
Feeling very fortunate to be awarded a Programme Foundation Award from CRUK @cruk-si.bsky.social
This is a new area for the lab & lets us team up with @mariasecrier.bsky.social to tackle a big problem of how different cancers lose control of proliferation
This is a new area for the lab & lets us team up with @mariasecrier.bsky.social to tackle a big problem of how different cancers lose control of proliferation
Reposted by Cenk Celik
Bu hafta “Yapay Zekanın Politik Ekonomisi” etkinliğinde Altuğ Yalçıntaş hocamız “büyük veri” meselesini iktisadi ve siyasal boyutlarıyla ele alırken, aynı saatlerde Cenk Çelik hocamız Tek Hücre ve Uzamsal Boyutta Canlılık” atölyesinde “hücreler arası iletişim konusunu masaya yatırıyordu.
August 14, 2025 at 5:27 PM
Bu hafta “Yapay Zekanın Politik Ekonomisi” etkinliğinde Altuğ Yalçıntaş hocamız “büyük veri” meselesini iktisadi ve siyasal boyutlarıyla ele alırken, aynı saatlerde Cenk Çelik hocamız Tek Hücre ve Uzamsal Boyutta Canlılık” atölyesinde “hücreler arası iletişim konusunu masaya yatırıyordu.
Reposted by Cenk Celik
We recently published a review reflecting on challenges and opportunities in characterising cancer cell states and niches using spatial transcriptomics and integration with digital pathology, see full thread below. Thank you Molecular Oncology for the opportunity!
We, Secrier Lab UCL @ugiatucl.bsky.social Genetics Institute, discussed challenges in cell state identification using spatial transcriptomics in cancer research, now out in Molecular Oncology.
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org
August 12, 2025 at 5:54 PM
We recently published a review reflecting on challenges and opportunities in characterising cancer cell states and niches using spatial transcriptomics and integration with digital pathology, see full thread below. Thank you Molecular Oncology for the opportunity!
Reposted by Cenk Celik
📢 Our new preprint is out! We show how the common gut bacterium 𝘌. 𝘧𝘢𝘦𝘤𝘢𝘭𝘪𝘴 stops wound healing. It uses a metabolic pathway, extracellular electron transport (EET), to stress host cells, halting their migration. Watch WT bacteria (orange) stop the cells while the mutant (blue) doesn't!
August 11, 2025 at 12:38 AM
📢 Our new preprint is out! We show how the common gut bacterium 𝘌. 𝘧𝘢𝘦𝘤𝘢𝘭𝘪𝘴 stops wound healing. It uses a metabolic pathway, extracellular electron transport (EET), to stress host cells, halting their migration. Watch WT bacteria (orange) stop the cells while the mutant (blue) doesn't!
Reposted by Cenk Celik
Bilimler Köyü'nde gelecek hafta...
📍 Detaylı bilgi ve başvuru: bilimler.org/etkinlikler/
#bilimlerköyü
#villageofsciences
📍 Detaylı bilgi ve başvuru: bilimler.org/etkinlikler/
#bilimlerköyü
#villageofsciences
August 4, 2025 at 1:19 PM
Bilimler Köyü'nde gelecek hafta...
📍 Detaylı bilgi ve başvuru: bilimler.org/etkinlikler/
#bilimlerköyü
#villageofsciences
📍 Detaylı bilgi ve başvuru: bilimler.org/etkinlikler/
#bilimlerköyü
#villageofsciences
We, Secrier Lab UCL @ugiatucl.bsky.social Genetics Institute, discussed challenges in cell state identification using spatial transcriptomics in cancer research, now out in Molecular Oncology.
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org
July 26, 2025 at 8:17 AM
We, Secrier Lab UCL @ugiatucl.bsky.social Genetics Institute, discussed challenges in cell state identification using spatial transcriptomics in cancer research, now out in Molecular Oncology.
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
doi.org/10.1002/1878... #SpatialTranscriptomics #CancerResearch #SpatialNiches
Reposted by Cenk Celik
New preprint from the Secrier lab. @cenkcelik.bsky.social @mariasecrier.bsky.social present EnrichMap, a Python package to compute gene set enrichment scores in spatial transcriptomics data: tinyurl.com/yc48f4fx.
See an explainer thread from @cenkcelik.bsky.social here: bsky.app/profile/cenk....
See an explainer thread from @cenkcelik.bsky.social here: bsky.app/profile/cenk....
June 3, 2025 at 11:00 AM
New preprint from the Secrier lab. @cenkcelik.bsky.social @mariasecrier.bsky.social present EnrichMap, a Python package to compute gene set enrichment scores in spatial transcriptomics data: tinyurl.com/yc48f4fx.
See an explainer thread from @cenkcelik.bsky.social here: bsky.app/profile/cenk....
See an explainer thread from @cenkcelik.bsky.social here: bsky.app/profile/cenk....
Reposted by Cenk Celik
Want to uncover biologically meaningful patterns in spatial omics data? Check out our new method EnrichMap, details below. Work led by the brilliant @cenkcelik.bsky.social! #spatialomics #genesets
[Preprint alert]
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
June 2, 2025 at 12:30 PM
Want to uncover biologically meaningful patterns in spatial omics data? Check out our new method EnrichMap, details below. Work led by the brilliant @cenkcelik.bsky.social! #spatialomics #genesets
[Preprint alert]
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
June 2, 2025 at 11:23 AM
[Preprint alert]
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
We’re thrilled to introduce EnrichMap: a powerful new method for spatial gene set enrichment. It’s spatially aware, biologically meaningful and built for the next generation of spatial transcriptomics. www.biorxiv.org/content/10.1...
Reposted by Cenk Celik
Yaşamı tek bir hücrenin sınırlarından başlayarak uzamsal boyutlara taşıyoruz. Bu etknlikte, hücresel düzeyde bilginin nasıl aktarıldığını, düzenlendiğini ve farklı mekânsal ölçeklerde nasıl organize olduğunu birlikte inceleyeceğiz.++
May 24, 2025 at 4:26 PM
Reposted by Cenk Celik
Işık yalnızca çevremizi aydınlatmaz; aynı zamanda doğanın en temel sırlarını da içinde taşır. Bu etkinlikte, Cambridge Üniversitesi’nden Prof. Mete Atatüre ve Dr. Yusuf Karlı’nın yürütücülüğünde, ışığın klasik fiziğin ötesine geçen dünyasına adım atacağız. ++
May 15, 2025 at 9:57 AM
Işık yalnızca çevremizi aydınlatmaz; aynı zamanda doğanın en temel sırlarını da içinde taşır. Bu etkinlikte, Cambridge Üniversitesi’nden Prof. Mete Atatüre ve Dr. Yusuf Karlı’nın yürütücülüğünde, ışığın klasik fiziğin ötesine geçen dünyasına adım atacağız. ++
Reposted by Cenk Celik
Yaşamı tek bir hücrenin sınırlarından başlayarak uzamsal boyutlara taşıyoruz. Bu etknlikte, hücresel düzeyde bilginin nasıl aktarıldığını, düzenlendiğini ve farklı mekânsal ölçeklerde nasıl organize olduğunu birlikte inceleyeceğiz.++
April 9, 2025 at 4:06 PM
Yaşamı tek bir hücrenin sınırlarından başlayarak uzamsal boyutlara taşıyoruz. Bu etknlikte, hücresel düzeyde bilginin nasıl aktarıldığını, düzenlendiğini ve farklı mekânsal ölçeklerde nasıl organize olduğunu birlikte inceleyeceğiz.++
Reposted by Cenk Celik
Check out how 💪🏼Enterococci💪🏼 use lactic acid to suppress the inflammatory response and promote virulence. Project started by Brenda Tien during her PhD and brought home by the always excellent @ronni.bsky.social! 🥳
Enterococcus faecalis-derived lactic acid facilitates persistent and polymicrobial wound infections by suppressing macrophage activation https://www.biorxiv.org/content/10.1101/2025.01.31.635924v1
February 1, 2025 at 2:04 PM
Check out how 💪🏼Enterococci💪🏼 use lactic acid to suppress the inflammatory response and promote virulence. Project started by Brenda Tien during her PhD and brought home by the always excellent @ronni.bsky.social! 🥳
Reposted by Cenk Celik
Balancing tumour proliferation and sustained cell cycle arrest through proteostasis remodelling drives immune niche compartmentalisation in breast cancer https://www.biorxiv.org/content/10.1101/2025.01.08.632014v1
January 13, 2025 at 4:50 PM
Balancing tumour proliferation and sustained cell cycle arrest through proteostasis remodelling drives immune niche compartmentalisation in breast cancer https://www.biorxiv.org/content/10.1101/2025.01.08.632014v1
Reposted by Cenk Celik
New insights into the role of p21 in lung cancer from the fantastic @alexisbarr.bsky.social!
New Year, new paper! (Ok, it actually came out just before Christmas but who was working then?!)
Here we show that p21 promotes the survival of non-small cell lung cancer cells, under normal growth & after chemotherapy: rdcu.be/d4kvU
Here we show that p21 promotes the survival of non-small cell lung cancer cells, under normal growth & after chemotherapy: rdcu.be/d4kvU
Pro-survival roles for p21(Cip1/Waf1) in non-small cell lung cancer
British Journal of Cancer - Pro-survival roles for p21(Cip1/Waf1) in non-small cell lung cancer
rdcu.be
January 2, 2025 at 1:19 PM
New insights into the role of p21 in lung cancer from the fantastic @alexisbarr.bsky.social!
Reposted by Cenk Celik
1/🚀 Excited to share RegVelo, our new cell model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇
biorxiv.org/content/10.1101/2024.12.11.627935v1
biorxiv.org/content/10.1101/2024.12.11.627935v1
December 12, 2024 at 2:48 PM
1/🚀 Excited to share RegVelo, our new cell model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇
biorxiv.org/content/10.1101/2024.12.11.627935v1
biorxiv.org/content/10.1101/2024.12.11.627935v1